Communicable Disease Control and Prevention in Action

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City and County of San Francisco DEPARTMENT OF PUBLIC HEALTH POPULATION HEALTH DIVISION Communicable Disease Control and Prevention in Action Drs. Cora Hoover and Susan Philip Disease Prevention and Control Branch Population Health Division Public Health Committee Meeting San Francisco Health Commission Tuesday, April 18, 2017 1

San Francisco Department of Public Health Health Commission Director of Health Finance Information Technology Human Resources Compliance Policy & Planning Public Information Interdivisional Initiatives San Francisco General Hospital Laguna Honda Hospital Managed Care Ambulatory Care Primary Care Behavioral Health Environmental Health Community Health Equity & Promotion Disease Prevention & Control Office of Equity and Quality Improvement Office of Ops., Finance & Grants Mgmt. Center for Learning & Innovation PHA Domain Categories Transitions Governance, Administration and System Management Assessment and Research Policy Development Maternal, Child and Adolescent Health Jail Health Public Health Emergency Preparedness & Response Emergency Medical Services Applied Research, Community Health Epidemiology & Surveillance Center for Public Health Research Bridge HIV Assurance 2

Disease Prevention and Control Branch Dr. Susan Philip Public Health Laboratory Dr. Godfred Masinde STD/HIV Prevention (Clinical and Biomedical) Dr. Stephanie Cohen Communicable Disease Control and Prevention Dr. Cora Hoover TB Prevention and Control Dr. Chris Keh Disease Intervention Teams Diane Portnoy

OUR MISSION Drawing upon community wisdom and science, we support, develop, and implement evidence-based policies, practices, and partnerships that protect and promote health, prevent disease and injury, and create sustainable environments and resilient communities. OUR VISION To be a community-centered leader in public health practice and innovation. STRATEGIC DIRECTIONS PHD STRATEGIES AND PERFORMANCEMEASURES 2012-2015 PUBLIC HEALTH ACCREDITATION (PHA) DOMAIN CATEGORIES ASSESSMENT / RESEARCH POLICY DEVELOPMENT ASSURANCE GOVERNANCE, ADMINISTRATION, AND SYSTEMS MANAGEMENT 1. Superb knowledge management systems and empowered users 2. Assessment and research aligned with our vision and priorities 3. Policy development with collective impact 4. Assurance of healthy places and healthy people 5. Sustainable funding and maximize collective resources 6. Learning organization with a culture of trust and innovation STRATEGY 1 : Build an integrated information and knowledge management infrastructure that enables us to monitor health, to inform and guide activities, and to improve staff and systems performance. PERFORMANCE MEASURES: 1.1.Build a strong, highly functional information technology (IT) and technical assistance infrastructure in alignment with Department of Public Health IT strategy. 1.2 Establish a highly functional, integrated infectious disease system to collect and report data and to deliver and monitor public health actions. STRATEGY 2: Integrate, innovate, improve, and expand efforts in community and environmental assessments, research, and translation. PERFORMANCE MEASURES: 2.1 Create an action plan that supports division priorities. 2.2 Build cross-section interdisciplinary teams to improve health outcomes and programmatic activities. STRATEGY 3: Conduct effective policy and planning that achieves collective impact to improve health and wellbeing for all San Franciscans. PERFORMANCE MEASURES: 3.1 Establish a division-wide Performance Management, Equity and Quality Improvement Program. 3.2 Establish systems and partnerships to achieve and maintain Public Health Accreditation. 3.3 Develop a prioritized legislative agenda and strategic implementation plan to address health status and inequities. STRATEGY 4: Lead public health systems efforts to ensure healthy people and healthy places PERFORMANCE MEASURES: 4.1 Establish community-centered approaches that address the social determinants of health and increase population well-being. 4.2 Sustain and improve the infrastructure and capacity to support core public health functions, including legally mandated public health activities. STRATEGY 5: Increase administrative, financial and human resources efficiencies within the division PERFORMANCE MEASURES: 5.1 Establish a centralized business office for the division. 5.2 Appropriately address the human resource issues regarding civil service and contract employees. 5.3 Establish a centralized grants management and development system for the division. STRATEGY 6: Build a division-wide learning environment that supports public health efforts. PERFORMANCE MEASURES: 6.1 Establish a division-wide Workforce Development Program. 4

Communicable Disease Control and Prevention (CDCP): Scope 70+ communicable diseases (and counting ) Emerging infections: preparedness and response Ebola traveler monitoring; Zika response; ruleouts of other diseases Enteric bacterial infections; Vector-borne diseases; Vaccine-preventable diseases Outbreaks (For example: Restaurantassociated outbreaks; Influenza and viral gastroenteritis outbreaks in Skilled Nursing Facilities)

What is the Role of CDCP? Prevent disease by promoting access to immunizations in San Francisco; distribute vaccines to safety net providers (>40K flu shots/year) Case management of pregnant patients with Hepatitis B infection AITC Immunization and Travel Clinic Full menu of adult and teen vaccines Travel vaccines TB testing Blood testing Receive communicable disease reports from labs and medical providers Investigate cases (medical records, interviews) Take action to interrupt transmission (depends on public health significance of the disease) Compile surveillance data; report to California Department of Public Health Act as liaison between medical community and CDPH/CDC

CDCP Team and Partners Director/CD Controller Medical Epidemiologist/AITC Immunization and Travel Clinic Medical Director Immunization Coordinator AITC nursing and clerical staff Disease Intervention Coordinator (cross- Branch) Program Coordinators Disease Investigators Public Health Nurse Epidemiologists Health Educator SFDPH partners Public Health Lab PHEPR Environmental Health Maternal, Child, Adolescent Health

Informing the public and medical providers http://www.sfcdcp.org/

CDCP Zika Response: Health Alerts http://www.sfcdcp.org/healthalerts.html

CDCP Zika response (MCAH collaboration): Health education materials http://www.sfcdcp.org/zika

Zika virus basics Transmitted to humans by Aedes mosquitos Sexual transmission is unique to Zika (among mosquito-borne viruses) Most infections are asymptomatic Symptoms are fever, rash, joint pain, conjunctivitis Can be transmitted in utero to the developing fetus Causes a spectrum of birth defects if infection occurs during pregnancy Stillbirth and miscarriage Microcephaly Other structural brain abnormalities Ocular abnormalities; hearing loss Limb contractures Zika Virus. Lyle R. Petersen, et al. N Engl J Med 2016; 374:1552-1563

Zika virus emergence Prior to 2007, circulated at a low level in Africa and Southeast Asia; scattered outbreaks 2007-2014 Likely spread to Latin America in 2014; first cases noted in Brazil in 2015 Current outbreaks in most countries or territories in Latin America and the Caribbean, including Puerto Rico and the U.S. Virgin Islands Local transmission in Florida and Texas https://wwwnc.cdc.gov/travel/page/zika-information

Potential risk of birth defects due to Zika US Zika Registry data analysis 6% of fetuses or infants had birth defects If infection occurred in the first trimester, 11% had birth defects Brazil analysis Bahia state (modeling) 1-13% risk of microcephaly if infection occurred in the first trimester More detailed understanding is emerging over time Honein et al. Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika during Pregnancy. JAMA. 2016 Dec 15. Johansson et al. Zika and the Risk of Microcephaly. NEJM. 2016 May 25.

United States Total (as of 3/22/17) 5,158 Pregnant (as of 3/14/17) 1,617 Live-born infants with birth defects 54/1,228 Zika by the numbers Sexually transmitted 45 Locally acquired (FL; TX) 222 California (as of 3/24/17) Total Zika cases 527 Pregnant 102 Live-born infants with birth defects 5 Sexually transmitted 6 San Francisco (as of 12/31/16) Zika testing requests tracked 849 San Francisco (as of 3/24/17) Total Zika cases 34 http://www.cdph.ca.gov/healthinfo/discond/documents/travelassociatedcasesofzikavirusinca.pdf http://www.cdc.gov/zika/geo/united-states.html http://www.cdc.gov/zika/geo/pregwomen-uscases.html http://www.cdc.gov/zika/geo/pregnancy-outcomes.html

SFDPH CDCP Zika response (1) Informing and supporting medical providers Health Advisories Respond to inquiries regarding travel and testing Tracking public health testing requests Act as liaison between providers and CDPH lab Receive testing results and forward them to providers with interpretation Case investigation; prevention of transmission Interview cases Counsel regarding prevention of sexual transmission and appropriate delay of conception Male cases were offered participation in the CDC Persistence of Zika Virus in Semen Study (now closed) Informing the public FAQs Zika webpage (http://www.sfcdcp.org/zika) Meeting with community groups

SFDPH CDCP Zika response (2) Pregnant patients and their infants are referred to Maternal, Child and Adolescent Health for public health nursing follow up Ensure enrollment of pregnant patients and their infants in the CDC Zika Pregnancy registry This month CDCP was awarded a Zika Response Grant from CDPH for $225,000. Planned enhanced activities: Public Health Nursing investigation and follow-up of cases, with focus on pregnancies Further education and outreach to medical providers Data quality and timeliness Mobile enabled online resources for providers and public

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