FEBRUARY 4 TH, 2017 PROGRAM CHAIRS REAL INTERCONTINENTAL HOTEL, SAN JOSE, COSTA RICA RESERVE YOUR SPACE TODAY! PLEASE CONTACT:

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FEBRUARY 4 TH, 2017 REAL INTERCONTINENTAL HOTEL, SAN JOSE, COSTA RICA PROGRAM CHAIRS Dr. Carlos Eduardo Zúñiga Orlich Medical Oncologist President, Costa Rican Association of Medical Oncology (ACOMED) Faculty member, Hospital San Juan de Dios and Hospital Cima Dr. Joao Manuel Baptista Da Palma Medical Oncologist Hematologist University of Costa Rica Hospital San Juan de Dios, San Jose Costa Rica RESERVE YOUR SPACE TODAY! PLEASE CONTACT: Dr. Carlos Eduardo Zúñiga Orlich czuniga_orlich@hotmail.com Dr. Denis Landaverde Professor of Medicine/ Medical Oncology, University of Costa Rica Chief of Medical Oncology Service Mexico Hospital, San Jose Costa Rica

PO BOX 71083 Maplehurst, Burlington, ON Canada, L7T 4J8, info@oncologyeducation.com June 9, 2016 Past Event Sponsors Alexion Pharmaceuticals Amgen Canada Inc Astellas Pharma AstraZeneca Canada Inc Bayer Inc Boehringer Ingelheim GmbH Bristol-Myers Squibb Canada Celgene Inc Eisai Limited Eli Lilly Canada Inc Genomic Health, Inc Dear Industry Partner, On behalf of the Organizing Committee (Dr. Carlos Eduardo Zúñiga Orlich, Dr. Joao Manuel Baptista Da Palma and Dr. Denis Landaverde) and OncologyEducation.com, we would like to invite you to join us as a sponsor for the Best of SABCS 2017 Annual Meeting held in San Jose, Costa Rica on February 4th, 2017 at the Real Intercontinental Hotel. OncologyEducation.com s Best of the SABCS 2017 Annual Meeting will present a summary of the most significant treatment advances presented at the annual San Antonio Breast Cancer Symposium. Presentations will be given by international and local key opinion leaders and focus on the latest research with in-depth analysis and discussion to improve the current standard of cancer care. Please review our exhibitor prospectus and contact us to secure your sponsorship program, or a symposium spot. We value your partnership as a sponsor and we look forward to working with you. Don t hesitate to contact us if you have any questions. We look forward to seeing you in San Jose! Sincerely, Gilead Sciences, Inc Janssen Inc Leo Pharma Inc Dr. Carlos Eduardo Zúñiga Orlich Lundbeck Canada Inc Merck & Co., Inc Novartis AG Dr. Joao Manuel Baptista Da Palma Pfizer Canada Inc Hoffmann-La Roche Ltd Sanofi Pasteur Limited Dr. Denis Landaverde Takeda Canada Inc 2 PO BOX 71083 Maplehurst, Burlington, ON Canada, L7T 4J8, info@oncologyeducation.com facebook.com/oncologyeducation

Excellent speaker who synthesized the recent data, and in context, discussed side effects management very practical. Best of ASCO Attendee Well done, again. Love the quick moving, full of information format. Best of Oncology West Attendee Complicated [topic] with new, practical and changing data presented clearly. Best of Oncology East Attendee THE EDUCATIONAL RESOURCE FOR ONCOLOGY PROFESSIONALS OncologyEducation.com is a comprehensive resource providing evidence-based educational content exclusively developed and authored by a leading international Faculty of oncology physicians. All content focuses on presenting timely, unbiased information for the oncology community, including oncologists and other related specialists, physicians, nurses, pharmacists, students, residents and researchers. OncologyEducation.com resources are updated regularly and include reports on recent advances in literature and clinical trials, conference updates and presentations, and disease-specific information, all of which are delivered through integrated online and mobile platforms. Accredited Continuing Medical Education (CME) events are hosted several times a year throughout the world and online, and focus on the latest scientific information for improvements in standards of care in cancer management and treatment. OncologyEducation.com was envisioned and established by Dr. Sunil Verma and Dr. Scott Berry in 2007. Dr. Verma is professor and Head of the Department of Oncology at the University of Calgary and the medical director at the Tom Baker Cancer Centre. Dr. Berry, a medical oncologist, Chairs the Gastrointestinal Disease Site Group at the Sunnybrook Odette Cancer Centre and is an associate professor at the University of Toronto. Since its inception, the OncologyEducation.com audience has grown considerably, thanks to our growing social media network. OncologyEducation.com has over 8,000 registered members, more than 2,400 Facebook fans, over 2,500 Twitter followers, and more than 2,200 LinkedIn followers. We feature monthly online webinars with expert commentary which are then archived on our site and have received some of the most viewers of any resource on our site. These online events cover a wide range of tumour sites and meet the needs of our audience in Canada and internationally. twitter.com/onced linkedin.com/company/oncologyeducation-com 3

MEET THE ORGANIZING COMMITTEE Dr. Carlos Eduardo Zúñiga Orlich Medical Oncologist President, Costa Rican Association of Medical Oncology (ACOMED) Faculty member, Hospital San Juan de Dios and Hospital Cima Dr. Joao Manuel Baptista Da Palma Medical Oncologist Hematologist University of Costa Rica Hospital San Juan de Dios, San Jose Costa Rica Dr. Denis Landaverde Professor of Medicine/ Medical Oncology, University of Costa Rica Chief of Medical Oncology Service Mexico Hospital, San Jose Costa Rica 4 PO BOX 71083 Maplehurst, Burlington, ON Canada, L7T 4J8, info@oncologyeducation.com facebook.com/oncologyeducation

FEBRUARY 4 TH, 2017 8:00 a.m. to 6:00 p.m. Real Intercontinental Hotel San Jose, Costa Rica TENTATIVE AGENDA February 4th, 2017 7:00 a.m. - 7:30 a.m. REGISTRATION, EXHIBITS & BUFFET BREAKFAST 7:30 a.m. - 8:30 a.m. Breakfast Symposium 8:30 a.m. - 8:45 a.m. Welcome Address by Chairs 8:45 a.m. - 9:15 a.m. Advances in Early Breast Cancer: Endocrine Therapy 9:15 a.m. - 9:45 a.m. Advances in Early Breast Cancer: Chemotherapy and Targeted Therapy 9:45 a.m. - 10:15 a.m. Neoadjuvant Treatment of Breast Cancer 10:15 a.m. - 10:30 a.m. Panel Discussion 10:30 a.m. - 10:45 a.m. BREAK 10:45 a.m. - 11:15 a.m. Achievements in Breast Cancer Research 11:15 a.m. - 12:15 p.m. Radiation Oncology Highlights 12:15 p.m. - 1:45 p.m. Lunch Symposium 1:45 p.m. - 2:15 p.m. Surgical Oncology Highlights 2:15 p.m. - 2:45 p.m. Biology and Pathology Insights 2:45 p.m. - 3:00 p.m. Panel Discussion 3:00 p.m. - 3:15 p.m. BREAK 3:15 p.m. - 3:45 p.m. Metastatic Breast Cancer: ER Positive 3:45 p.m. - 4:15 p.m. Metastatic Breast Cancer: HER2 Positive 4:15 p.m. - 4:45 p.m. Metastatic Breast Cancer: Triple Negative 4:45 p.m. - 5:00 p.m. Panel Discussion 5:00 p.m. - 5:15 p.m. Concluding Remarks by Chairs 5:30 p.m. - 7:00 p.m. EVENING SYMPOSIUM Visit: www.oncologyeducation.com/events

BEST OF SABCS SAN JOSE SPONSORSHIP LEVELS Sponsorship Entitlements Platinum ($40,000) Gold ($26,000) Bronze ($20,000) Promotional Materials Conference Badges Delegate Exposure Acknowledgement of sponsorship level on conference Website Acknowledgement of sponsorship level on venue signage Acknowledgement of sponsorship level on all other documents 1 form of promotional material in delegate package 1 additional form of promotional material in delegate package 5 Complimentary full registrations 3 Complimentary full registrations 1 Complimentary full registrations Additional Sponsor Badges Up to 2 additional badges may be purchased by any support level sponsor for $750/each. Exhibit table (size to be confirmed by allowable venue space) Other Right of space for private chat. (Breakfast, Lunch or Dinner) BREAKFAST, LUNCH & DINNER SYMPOSIUM SPONSOR $10,000 (EACH) Symposia features include: Logo display on lectern in presentation rooms Opportunity for short address/presentation during meal Marketing services/collateral development Project/registration management Naming rights of the Symposia Archiving on OncologyEducation.com Sponsor signage at Symposia venue 5 additional full registrations Meals Audience response systems AV services *All symposia promotion material must be approved by OncologyEducation.com and contain both the OncologyEducation.com and event logo. Symposia attendance is only available to Best of SABCS San José event registrants. Two concurrent symposia on different topics possible. Please make all cheques payable to ACOMED: San Jose - Escazu Hospital Cima, Septimo Piso, Consultorio 18. PO BOX 71083 Maplehurst,Burlington, ON L7T 4J8, info@oncologyeducation.com facebook.com/oncologyeducation twitter.com/onced linkin.com/company/oncologyeducation-com

` APPLICATION FORM FOR SPONSORS BEST OF SABCS 2017 ANNUAL MEETING SAN JOSE FEBRUARY 4 TH, 2017 REAL INTERCONTINENTAL HOTEL, SAN JOSE, COSTA RICA Company Name: Company Address: State/Province: City: Zip/Postal Code: Exhibitor Contact & Title: Country: Phone: Ext. Email: EDUCATIONAL GRANTS Exhibitor Pricing* $40,000 Platinum $26,000 Gold $20,000 Bronze Symposia Packages: $10,000/ea* Breakfast Lunch Dinner Additional Sponsor Badge: $750/ea* 1 2 Other COMMERCIAL SPACE/SUPPORT Industry Badge-Only Sponsor: $1,500/ea* 1 2 3 (Max 3) PAYMENT OPTION Check Visa Mastercard Total Amount in US Funds: $, Please make checks payable to: CancerLink Ontario, Inc. Name as appears on Credit Card: Mail to: ACOMED San Jose - Escazu Hospital Cima, Septimo Piso, Consultorio 18. Account Number: Verification Code Expiry Date (MM-YR) Credit Card Billling Address: Same as Above State/Province: City: Zip/Postal Code: Country: Authorization Signature: The person signing certifies that he/she has the authority to sign this contract and has read and accepts the Terms & Conditions on the previous page of this prospectus. Email Address for payment Confirmation: Same as Above twitter.com/onced linkedin.com/company/oncologyeducation-com 7

TERMS AND CONDITIONS 1. ALLOCATION OF EXHIBIT SPACE: OncologyEducation.com (OE) intends to allocate the selection of exhibit space for exhibitors booths on a first-come, first-served basis. OE reserves the right to make changes to the floor plan. 2. PAYMENT: Exhibitors shall make payments via check or credit card, payable in full to ACOMED: Mail checks to: San Jose - Escazu Hospital Cima, Septimo Piso, Consultorio 18. Funds must be in US dollars. Full payment must be received at time of application. 3. CANCELLATION OF CONTRACT: If cancellation is received by December 20, 2016, a 50% refund will be credited. After that time, there shall be no refunds for cancellations. Exhibitor agrees that the total space rental fee for the cancelled space shall be retained or paid to ACOMED. 4. ELIGIBLE EXHIBITS: OE reserves the right to determine eligibility of any company or product to participate in the exhibit. OE can refuse or revoke rental of exhibitor booth space to any company whose display of goods or services is not, in the opinion of OE, compatible with the character and objectives of the exhibit. In such event, this agreement shall terminate and OE shall refund all funds paid to it. 5. SUBLETTING OF EXHIBIT SPACE: Exhibitors may not assign, sublet, or share their exhibitor booth space to or with another business or firm. Should an article of a nonexhibiting firm be required for operation or demonstration in an exhibitor s display, identification of such article shall be limited to the usual and regular nameplates, imprint, or trademark under which same is sold in the general course of business. 6. AGREEMENT TO INDEMNIFY, HOLD HARMLESS, AND WAIVE: (a) Exhibitor agrees to make no claim of any nature whatsoever against OE and its affiliates, their directors, officers, agents, servants, employees, subsidiaries, successors and assigns, or any of them, except for specified claims: (1) arising directly from the gross negligence of OE or its employees acting within the scope of their employment, and (2) caused by circumstances under the control of OE. This waiver shall include, without limitations: (i) loss, damage, or injury to any property of the exhibitor by fire, theft, destruction, vandalism, or any other cause, except that loss or damage directly attributable to the gross negligence of OE or its employees; (ii) any injury to the exhibitor, its agents, or employees by any cause, except for such injury directly attributable to the gross negligence of OE or its employees; (iii) loss, damage, or injury to the exhibitor s business by reason of space location or the failure to provide space for the exhibit, or by any failure to hold the exhibit as scheduled, and waiver as to such loss or injury shall here include claims arising from the gross negligence of OE, its employees or agents; (iv) loss, damage, or injury to the exhibitor s business caused by fire, electrical service interruption, or any other interruptive occurrence, and waiver as to such loss, damage, or injury shall here include claims arising from the gross negligence of OE, its employees, or agents; and (v) all consequential commercial damages arising out of any aspect of this agreement, including those damages resulting from the gross negligence of OE and its affiliates, their directors, officers, agents, servants, employees, subsidiaries, successors, and assigns, or any of them. (b) The exhibitor shall indemnify and hold OE and its affiliates, their directors, officers, agents, servants, employees, subsidiaries, successors, and assigns, or any of them, harmless from and against any and all claims, penalties, damages, losses, costs, charges, and expenses whatsoever, including reasonable attorney s fees and costs arising out of the exhibitor s participation in the exhibit, except where such claims are directly attributable to the gross negligence of OE or its employees, including without limitation the following: (i) damage or injury to any person, persons, or property arising from or by reason of the occupation and use of the exhibit space; (ii) acts done or caused to be done by Exhibitor, its agents, employees, guests, or invitees; (iii) any breach by the exhibitor of its obligations hereunder; (iv) any loss, damage, or destruction to property of the exhibit facilities caused by the exhibitors, its agents, employees, guests, or invitees; and (v) any loss, theft, misappropriation or otherwise, or damage or destruction of any property of the exhibitor or its employees brought into the exhibit facility. (c) Exhibitor hereby agrees to waive the right of subrogation by its insurance carriers to recover losses sustained under its insurance contract for real and personal property, when permitted by its contracts with its carriers. The exhibitor understands that OE does not maintain insurance covering the exhibitor s property and it is the responsibility of the exhibitor to obtain such insurance. 7. BADGES: Badges will be required for entry into the exhibit hall at all times. Business cards are not to be used in exhibit badge holders. OE has the right to limit the total number of exhibitor credentials that may be included with each booth. 8. SECURITY: Exhibitors are responsible for the security of their exhibit. Exhibitors are solely responsible for securing all sensitive or valuable items. If insurance to cover the above is desired, it must be placed and paid for by the individual exhibitor. 9. ACCEPTANCE: This agreement shall be deemed accepted by OE when received by an authorized representative of OE, either in person or upon receipt by Mail or other delivery method and confirmed by OE with an Exhibitor Space Contract acceptance form specifying booth assignment. 10. OTHER REGULATIONS: Any and all matters not specifically covered by preceding rules and regulations shall be subject solely to the decision of show management. 11. ENTIRE AGREEMENT: The provisions contained herein constitute the entire agreement and supersede all previous communications, representations, and agreements either verbal or written, between the parties hereto with respect to the subject matter hereof. *Sponsorship information may be changed by OncologyEducation.com without prior notice and the new rates will apply only to sponsors who have not yet committed to support for the event.

PO BOX 71083 Maplehurst Burlington, ON Canada, L7T 4J8 info@oncologyeducation.com facebook.com/oncologyeducation twitter.com/onced linkedin.com/company/oncologyeducation-com Download the Oncology Education ipad and iphone App. Now available on itunes!