Invest for Impact: Global Fund Session. 29 th Stop TB Partnership Coordinating Board Meeting Berlin 17 th May

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Invest for Impact: Global Fund Session 29 th Stop TB Partnership Coordinating Board Meeting Berlin 17 th May

Agenda 1 TRP Review Window 1 2 Absorption of TB grants 3 Catalytic Funding 1

Largest review window in Global Fund history The 91 funding requests represented almost US$4.8 billion, US$920 million PAAR, and $60.1 million in Matching Funds This is nearly 47% of the total allocation for the current period Funding request submission and allocation by application approach (window 1) Amount of allocation, out of $10.3 billion Other windows Full review Tailored Program continuation $2.3B $0.8B $1.6B $5.5B Funding requests submitted, out of 228* 72 7 12 137* *based on current projections 2

Summary of TRP recommendations 91 applications reviewed 95% of applications recommended for grant-making 19 in Full/Tailored Review 72 in Program Continuation All Application Approaches 11% 4% 5% 16 2 18 89% 96% 95% Grant-making Iteration Grant-making Iteration Grant-making Iteration The TRP notes that many Program Continuation requests were approved for grant-making with the expectation of an upcoming program review. This may lead to reprogramming during implementation. 3

TB and TB/HIV funding request submissions for window 1 14 TB applications ($.28 billion) 14 TB/HIV applications ($1.75 billion) 2 TB/HIV/malaria applications both program continuation ($.13 billion) TB Application Approach TB/HIV Application Approach 1 2 11 3 2 9 Program Continuation Tailored Full Program Continuation Tailored Full 4

General lessons learned Window 1 1. 1 Good quality of proposals in this funding window 2. 2 Differentiated application process positively received 3. 3 More boldness needed with matching funds applications 4. 4 Sustainability not yet sufficiently addressed 5. 5 Malaria resurgence concern in some countries in Central and Eastern Africa 5

TB Lessons learned Expansion of Xpert continuing quickly but optimization of use still needed Digital radiography: Efforts to expand access to the CXR, however operationalization issues and expected outcomes related to digital x-rays missing. Countries moving slowly on MDR-TB diagnosis (case finding targets not achieved). Most countries are moving to shortened regimen however a few holding back for lack of SLD DST. TRP encourages prioritizing short-course regimen as capacity for SLD DST is built for treatment optimization and better patient outcomes. TB prevalence surveys have confirmed large proportion of missing TB cases in many settings. Funding requests appropriately mention interventions to find these cases, but lack sufficient analysis of who is missing, where and why. Missing bold steps and significant innovation. Countries with big TB/HIV disease burdens making tremendous progress in bi-directional testing and ART coverage. Slow progress if at all in low TB/HIV burden countries. IPT: % of PLHIV on IPT is low overall. Human rights/gender issues broadly are not well addressed in TB applications.

TB grants 7

Absorption rates of the three diseases in the active grants TGF global active grants absorption rate 80% 70% 60% 50% 40% 30% 20% 10% 0% 76% 73% 68% 71% 44% HIV/AIDS Tuberculosis Malaria HIV/TB Total Source: Global Fund data Outcome of active grants reviewed till end of Q1 2017 8

TB active grants absorption rates compared to other disease components TB absorption rates compared to other disease components in regions Western Africa 72% 44% 72% 60% Southern and Eastern Africa 88% 32% 55% 73% South and East Asia 75% 69% 68% Middle east and north Africa 71% 52% 67% 75% LAC 73% 48% 62% 59% High Impact Asia 73% 69% 63% 81% High Impact Africa 2 80% 58% 67% 68% High Impact Africa 1 72% 24% 76% 69% Eastern Europe and Central Asia 67% 82% 52% Central Africa 47% 54% 59% 61% 0% 50% 100% 150% 200% 250% 300% HIV/AIDS HIV/TB Malaria Tuberculosis Source: Global Fund data 9

Active TB grants absorption rates by regions: Regional TB absorption rates (%) Eastern Europe and Central Asia 52% 184,283,315 LAC Western Africa Central Africa 59% 60% 61% 96,654,840 97,421,590 65,289,246 High Impact Africa 2 South and East Asia High Impact Africa 1 Southern and Eastern Africa Middle east and north Africa High Impact Asia 68% 68% 69% 73% 75% 81% 354,943,388 153,131,457 422,634,793 164,662,257 102,211,614 1,449,226,390 40% 45% 50% 55% 60% 65% 70% 75% 80% 85% Source: Global Fund Data Investments amounts in USD 10

Active HIV/TB grants absorption rates by regions: Regional HIV/TB absorption rates(%) High Impact Africa 1 Southern and Eastern Africa Western Africa LAC Middle east and north Africa Central Africa High Impact Africa 2 24% 32% 44% 48% 52% 54% 58% 311,944,551 399,489,595 36,168,352 77,924,323 8,622,877 59,099,621 206,654,066 High Impact Asia Eastern Europe and Central Asia 69% 82% 43,816,944 151,539,633 20% 30% 40% 50% 60% 70% 80% 90% Source: Global Fund data Investment amounts in USD 11

Top 5 and least 5 countries with TB absorption rates (HI) (%) TB absorption rates (%) in high impact countries 120% 100% 100% 89% 89% 84% 83% LEAST COUNTRIES WITH TB ABSORTION 80% 66% 64% 60% 56% 50% 40% 38% 20% 0% HIA.9 HIA.1 HIA.5 HIA1.6 HIA.7 HIA1.4 HIA1.2 HIA2.4 HIA2.8 HIA2.3 Source: Global Fund Data ¾ of the TB active investments are in the high impact countries 12

Comparing TB absorption with other disease components in least performing countries Absorption rates of disease components in 5 TB least performing countries 90% 80% 70% 60% 50% 40% 76% 78% 64% 68% 57% 38% 73% 66% 66% 60% 82% 56% 77% 63% 50% 30% 20% 10% 0% HIA1.2 HIA2.3 HIA1.4 HIA2.4 HIA2.8 HIV/AIDS Malaria Tuberculosis Source: Global Fund data 13

Permanent Secretaries and NTP Managers from HIA2; Nairobi, Feb,2017 14

Follow-up action tracker on absorption Country Grant Component Grant Amount signed HIA2.3 TB 40.6mill USD 33% 63% TB/HIV 63.7mill USD 42% 72% HIA2.4 TB 21.4mill USD 56% 86% TB/HIV 40.6mill USD 44% 74% HIA2.5 TB 21.7mill USD 39% 69% TB/HIV 21.4mill USD 42% 72% HIA2.6 TB/HIV 21.7mill USD 46% 76% HIA2.1 TB 58.2mill USD 63% 93% HIA2.2 TB 63.7mill USD 45% 75% HIA2.8 TB 38.8mill USD 48% 78% Percentage disbursed to signed amounts (%) Dec. 2016 Sept. 2017 target June 2017 Priority action points Planning Issues/Forecasting Issues Coordination/Process Funding Issues Infrastructure Partnership Issues 15

Catalytic Funding 16

Overview of Board-approved Catalytic Investments 2017-2019 HIV TB Malaria RSSH Broader Strategic $200m $190m $202m $166m $42m Key Populations; Human Rights; Adolescent Girls & Young Women Finding missing TB cases Malaria Elimination, Drug and LLIN Resistance, Piloting first Malaria Vaccine Program Sustainability, Service Delivery & Health Workforce; Supply Chain Strengthening; Data Systems & Use for Program Quality; Community Rights & Gender Prospective Country Evaluations; Emergency Fund Illustrative Modality Total Funding (US$ m) % of Funding Matching Funds 356 44.5% Multi-County Proposals 272 34.0% Strategic Initiatives 172 21.5% Total 800 ~ 80% directly to country programs

Matching Funds - Strategic Priorities HIV TB RSSH Malaria Scale-up of evidence-informed HIV programs for key populations Removing human rights barriers to access to HIV services Addressing HIV amongst adolescent girls and young women Finding missing TB and drug-resistant TB cases Integration of service delivery and improvement of health workforce Improving data systems, generation and use Catalyzing market entry of new long-lasting insecticidal nets Allocation letter specifies strategic priority area(s) and matching funds available 18

TB Catalytic Matching Funding No. Country Matching Funding (US$ million) Allocation (US$ million) Submission window 1Bangladesh 12 97.93 W1 2DRC 10 56.65 W1 3Indonesia 15 102.41 W2 4Myanmar 10 82.94 W2 5Nigeria 14 107.49 W2 6Pakistan 13 130.16 W2 7Philippines 10 78.54 W1 8South Africa 6 35.59 W4 9Tanzania 6 25.84 W2 10Ukraine 7 48.64 W2 11 Kenya 6 45.50 W2 12Mozambique 6 45.12 W2 Total 115 856.81 (47%) 19

TB Strategic Initiative-US$10 million The main objective of catalytic strategic initiative is to address barriers and apply innovative practical approaches and tools to accelerate progress towards finding the missed TB cases The focus is 12 catalytic matching funding countries with additional impact in priority 14 countries and support to a regional initiative in West and Central Africa Overall SI will catalyze impact in 26 countries with 83% of missing cases globally and expected XXX additional cases by 2019 Discussion on-going with WHO and Stop TB Partnership on specific activities, performance framework and measurable impact 20

Strategic Initiative: Global Impact Counties Incidence Cases Missing cases Allocation (US$ million) Submission 1 India 2,840,000 1,740,435 1,099,565 279.92 W2 2 Vietnam 128,000 102,676 25,324 47.28 W2 3 Thailand 117,000 66179 50,821 13.00 W2 4 Cambodia 59,000 35,638 23,362 13.81 W2 5 Ethiopia 191,000 137,960 53,040 51.59 W2 6 Uganda 79,000 43,736 35,264 21.10 W1 7 Zambia 63,000 41,588 21,412 10.00 W2 8 Zimbabwe 38,000 28,225 9,775 23.77 W1 9 Cote D'Ivoire 36,000 22,879 13,121 13.60 W1 10 Ghana 44,000 14,999 29,001 16.00 W2 11 Sudan 35,000 20,006 14,994 12.26 W1 12 Madagascar 57,000 29,939 27,061 9.30 W1 (F) 13 Malawi 33,000 17,104 15,896 9.00 W1 14 Cameroon 49,000 26,570 22,430 10.59 W3 1,441,066 531.22 21

Thank you! Questions? 22