and Enterprise Successes and Challenges From IHL perspective From Polytechnic perspective

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Outline Transformation f off the Singapore g p Economy National N ti l FFrameworkk ffor IInnovation ti and Enterprise p Successes and Challenges From IHL perspective From Polytechnic perspective

Transformation of the Singapore Economy Prime Minister s s National Rally Speech, 2005...two major thrusts that would characterise Singapore's economy in the next 15 to 20 years. One is to foster innovation and enterprise and the other to exploit research and development.........human imagination i and enterprise were what ht Singapore would need to stay ahead

National Framework for Innovation and Enterprise Knowledge Creation Knowledge Diffusion Knowledge Usage Good Science Strategic Research Program, Competitive Research Program, Research Center of Excellence, Fellowship Award CREATE Academic Entrepreneurship Programs Innovation Funding NUS($9 million) NTU($6.5 million) SMU($6.5 million) Management Support Enterprise Board Effective Tech Transfer Processes National IP Policy Translational Grants for Polytechnics Innovation Vouchers for SMEs Enterprise Support Proof of Concept f Technology Incubation Scheme Early Stage Venture Funds Entrepreneurial Students Entrepreneurial Education Programs Strong Faculty Industry t Links Entrepreneur in residence Industry outreach programs Existing firms Start ups Firms Innovation Policy Center Strengthening links between Research & Industry Singapore Government encourages nexus between R&D and business as well as develop Singapore innovation capacities in downstream, problem solving research Singapore Universities/Research Institutes/Polytechnics maintain strong links with ih industry to ensure research outputs will translate into products or services to benefit society

Source: Exploit Technologies Pte Ltd Smart tagging, that is, the use of radio frequency identification (RFID) is creating waves in the way products could be tracked and traced in real time at any location. Leveraging on the extensive RFID development expertise and experience of Singapore, gp Exploit Technologies will invest $10 million over three years to execute solicited proof of concept (POC) proposals for A*STAR's comprehensive suite of RFID technologies with industry partners. The POCs are aimed at helping at local companies and end users in deploying and implementing RFID solutions quickly. Virus Detectives ti Veredus aim was to make one of the world s first commercially available Avian Influenza diagnostic kit. In July 2005, Veredus achieved its goal and announced that it was ready with a Kit that detects a gene specific to the H5N1 strain within four hours. Veredus utilized the proprietary nucleic acid diagnostic primers developed by the Genome Institute of Singapore (GIS). The kit has been tested in avian samples in Vietnam and Malaysia with excellent results showing no cross reactivity to other pathogens. Source: Exploit Technologies Pte Ltd

From NTU... Amaranth Medical Inc. is a Delaware C corporation incorporated in August 2006 to commercialize biodegradable stents to treat peripheral p p vascular disease ((PVD). ) The company p y is a research and development stage firm with offices in Palo Alto, California and in Singapore. Amaranth has obtained US$ 7.5M of financing through a Series A investment led by Charter Life Sciences of P l Alt Palo Alto, and d Bi Bio*One *O C Capital it l off Singapore. Si Th The ffunds d will ill b be used to advance the technology into proof of concept studies in man. Amaranth's core technology was developed in Singapore, at the Nanyang Technological University's School of Material Science & g g The Dean of the School of Material Science & Engineering. Engineering, Prof Freddy Boey, and the school's Vice Dean, Prof Subbu Venkatraman, have worked together over the last decade on novel materials. Amaranth is now focused on progressing its stents to the preclinical/clinical stages in the United States.«Less States Less Source: Singapore Straits Times

NUS Start-ups as a Pull for Industry Partnerships NUS Spin off Software to tackle mobile phone thefts WaveSecure locks phone by remote control, backs up personal data to secure server and wipe out sensitive data on the phone Industry partnership with Nokia (symbian phones) and Windows (mobile phones) Launched in India and Pakistan through telcos 11 MOZAT PTE LTD won the Red Herring 100 Asia Award in 2008

Classic licensing Pioneer Fibredrain Over the last 20 years, about 15 million metres of Fibredrain have been used in soil improvement projects in East and Southeast Asia, generating about $600,000 in royalites. Emeritus Prof Lee Seng Lip and colleagues From IHL perspective Some of the Challenges... Limited patent budget $$ need to identify & build value asap Evaluating more complex early stage technologies Recruiting, i motivating i and retaining i good technology transfer officers Managing Conflict of Interest Skepticism in Home grown technologies from spin offs or startups Nurturing more spin offs into successful SMEs for Singapore Managing expectations of stakeholders; khld Researchers, Management, Govt Agencies & Industry

NRF s Translational R&D (TRD) Fund Industry Developed IP Technology Translation IP Creation IP Recognition IP Development IHL,RI and Funding Agencies Upstream IP Polytechnics $$ The Polytechnics in Singapore Five Polytechnics same but dff different! Republic p Polytechnic is Singapore s gp newest polytechnic (Formed August 2002) 30 diploma programmes; 13,000 students (rising) Problem Based Learning (PBL) curriculum Applied R&D for capability development, to assist local industry and to enrich curriculum Use upstream IP from Universities or A*STAR, or create new IP, so IP Management is a necessity.

Polytechnics have Different Challenges Main purpose is to teach and develop workforce May have R&D Centres, but no Profs Almost all research is done part time Very well equipped, good links to Industry and Business, as well as to IHLs and RIs Many PhD and Masters level staff Time is the main challenge Perceived P i d value of applied research Translational R&D Example TRD Fund provides $$ for manpower New Project with NUS patent on producing enhanced silk (stronger technical textiles) Great G t interest t from Industry but too far away from market...need more proof on scale up, applications and specifications RP s s New Materials TDC work on scale up, R&D on yarn and fabric, new composite materials and rigorous testing

Book Vending Kiosk Electronic Control System Developed in conjunction with a local SME IP mostly know how captured as circuit diagrams, component lay outs, calibration and operations manuals, etc (copyright) Licensed to the SME for a one off off fee Retained rights to continue to develop similar (but not identical systems) Branding and recognition ii for RP High End IP (pharma) Active Early Engagement from OTD is key! New IP created in house patentable Possible new drug candidate Surfaces from TDC projects OTD monitors and guides IP management OTD advise on publication, patent search and commercialisation Decision from RP to pursue OTD perform IP evaluation

IP Policy IP Ownership: IP developed d by staff tff will be owned by RP when: as part of his duties; in fulfillment of his contract of employment; through the course of his participation in a research project of RP; or with the use of RP s Resources. Revenue Sharing for Staff Members:1/3 revenue share for inventors Recently reviewed and revised with assistance of IPOS / SPRING Singapore SCOPE IP initiative Thank You For Your Attention ti Dr Peter Kew, National University of Singapore E mail: peterkew@nus.edu.sg Dr Ian Law, Republic Polytechnic, Singapore E Mail Mil ian_law@rp.sg