Manu Thakral, PhD, ARNP

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Manu Thakral, PhD, ARNP CONTACT INFORMATION Kaiser Permanente Washington Health Institute Metropolitan Park East 1730 Minor Avenue, Suite 1619b Seattle, WA 98101 Phone: 206-287-2108 Email: thakral.m@ghc.org EDUCATION University of Massachusetts Boston 2010-2015 College of Nursing and Health Sciences Doctor of Philosophy Nursing (Population Health track) Dissertation: Pain Qualities and Their Persistence in the Elder Population Chairperson: Suzanne G. Leveille, PhD, RN Massachusetts General Hospital Institute of Health Professions, Charlestown, MA 2005-2008 Master of Science in Nursing Direct Entry Program, Specialty: Adult/Women s Health Tufts University, Medford, MA 1998-2002 Bachelor of Arts Major: Child Development, Community Health Certificate Program LICENSURE/ CERTIFICATION WA Licensed Advanced Practice Registered Nurse (APRN) ANCC certified Adult Nurse Practitioner (ANP-BC) NCC certified Women s Health Nurse Practitioner (WHNP-BC) POSTDOCTORAL TRAINING Kaiser Permanente Washington Health Research Institute 2015-current T-32 Postdoctoral Fellowship, Women and Aging Mentors: Andrea LaCroix, PhD, Michael Von Korff, ScD Research Associate: Multisite collaboration on projects throughout all phases of study design and implementation with an emphasis on comparative effectiveness of opioid risk reduction strategies, chronic pain epidemiology, cognitive-behavioral therapy for insomnia and aging, and health disparities in those with long term physical disabilities M. Thakral Page 1

DOCTORAL TRAINING University of Massachusetts Boston, 2011-2013 College of Nursing and Health Sciences Mentors: Suzanne Leveille, PhD, RN; Ling Shi, PhD Research Assistant: Performed SAS statistical analyses, manuscript preparation, and research presentations for the Maintenance of Balance, Independent Living, Intellect and Zest in the Elderly (MOBILIZE) Boston Study, an NIH-funded population-based prospective cohort study of novel risk factors for fall in an older population. Specific focus of research was in the functional consequences of musculoskeletal pain and stiffness in older adults. Prepared grant proposals to support dissertation research (unfunded). University of Massachusetts Boston 2010-2011 College of Nursing and Health Sciences Mentor: Suzanne Leveille, PhD, RN Study Coordinator: An Enhanced Medication Monitoring System, an NIH-funded (SBIR) randomized controlled trial to measure the effectiveness of a program which combined individualized personal interventions and a novel electronic pillbox with a web-based adherence tracking service. Outcomes were on medication adherence and hypertension control in older persons. ACADEMIC/PROFESSIONAL EXPERIENCE MGH Institute of Health Professions, Charlestown, MA 2006-2007 Supervisor: Ursula Kelly, PhD, ANP-BC, PMHNP-BC Research Assistant: Conducted (translator-assisted) surveys targeting immigrant non-english speaking female victims of intimate partner abuse to examine health care utilization, overall health status, and barriers to health care access, using both objective and subjective measurement tools. Tufts University School of Medicine, Boston MA 2002-2005 Department of Public Health Supervisor: Jeffrey Griffiths, MD, MPH Senior Research Technician: Performed laboratory techniques including plasma protein and cellular immunoassays on a cohort study of infants and their families by monitoring infection status to cryptosporidium parvum. Massachusetts General Hospital, Harvard Medical School, Boston, MA 2002-2003 Department of Radiation Oncology Supervisor: Simon Powell, MD, PhD, FRCP Research Technician: Assayed the effects of Tirapazamine (phase III anti-cancer agent) on survival of human tumor cells using cell survival experiments and protein assays. TEACHING EXPERIENCE University of Massachusetts Boston, College of Nursing and Health Sciences 2012-2014 NU212 Health Promotion and Teaching (Undergraduate Intermediate Writing Seminar) Course Instructor: Summer 2012, Spring 2014 M. Thakral Page 2

University of Massachusetts Boston, College of Nursing and Health Sciences 2012-2013 NS 668The Nurse Educator in the Academic Setting Advisor: JoAnn Mulready-Schick, EdD. MSN, RN, CNE Teaching Practicum: Spring 2012 CLINICAL EXPERIENCE Harborview Medical Center, Medical Respite, Edward Jefferson House 2017- current Group Health Research Institute, Immunization Program, Clinical Trials 2015-2016 Boston Health Care for the Homeless Program, Barbara McInnis House Respite Care 2012-2015 Massachusetts General Hospital Chelsea Healthcare Center, Urgent Care 2009-2012 Preventive Medicine Associates, Quincy International Health Center 2008-2010 Nurse Practitioner Boston Medical Center, Women s Health Outpatient Clinic 2007-2008 Four Women, Women's Health Services, Attleboro, MA 2007-2008 Registered Nurse PEER-REVIEWED PUBLICATIONS. Thakral, M., Walker, R. L., Saunders, K., Shortreed, S. M., Parchman, M., Hansen, R. N., Dublin, S., Von Korff, M. V. (2017). Impact of opioid dose reduction initiatives on chronic opioid therapy patients at higher risk for opioid-related adverse outcomes. (under review). Thakral, M., Walker, R. L., Saunders, K., Shortreed, S. M., Parchman, M., Hansen, R. N., Dublin, S., Von Korff, M. V. (2017). Comparing pain and depressive symptoms of chronic opioid therapy patients receiving dose reduction and risk mitigation initiatives to usual care. (under review). Thakral, M., Shi, L., Foust, J.B., Patel, K.V., Shmerling, R. H., Bean, J. F., Leveille, S. G (2017). Persistent pain quality as a novel risk factor for disability in community-dwelling elders with chronic pain. (under review). Thakral, M., Shi, L., Foust, J.B., Patel, K.V., Shmerling, R. H., Bean, J. F., Leveille, S. G (2016). Pain quality descriptors in community-dwelling older adults with nonmalignant pain. PAIN, 157(12), 2834 2842. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2014). A stiff price to pay: Joint stiffness predicts disability in an older population: The MOBILIZE Boston Study. Journal of the American Geriatric Society, 62(10), 1891-1899 Von Korff, M. V., Shortreed, S. M., LeResche, L. Saunders, K., Thielke, S., Thakral, M., Rosenberg, D., Turner, J. A. (2016). A longitudinal study of depression among middle-aged and senior patients initiating chronic opioid therapy. Journal of Affective Disorders, 211, 136-143. Von Korff, M., Walker, R. L., Saunders, K., Shortreed, S. M., Thakral, M., Parchman, M., Hansen, R. N., Dublin, S. (2016) Prevalence of prescription opioid use disorder among chronic opioid M. Thakral Page 3

therapy patients after health plan opioid dose and risk reduction initiatives. International Journal of Drug Policy, (in press). RESEARCH PRESENTATIONS Thakral, M., Walker, R. L., Saunders, K., Shortreed, S. M., Parchman, M., Hansen, R. N., Dublin, S., Von Korff, M. V. (2017). Impact of opioid safety initiatives on chronic opioid therapy patients at higher risk for opioid-related problems. (Paper presentation) Western Institute of Nursing Annual Meeting, Denver, CO. Thakral, M., LaCroix, A., Molton, I. R. (2016) Sex Differences in Health and Functioning of Individuals with Physical Disabilities. (Paper presentation). Western Institute of Nursing Annual Meeting, Anaheim, CA. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2015) Are Pain Quality Descriptors Associated with Disability in the Older Population? (Paper presentation) Eastern Nursing Research Society Annual Meeting, Washington, DC. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2014) Persistence of pain using pain quality descriptors in the elder population: The MOBILIZE Boston Study. (Poster) Gerontological Society of America Annual Meeting, Washington, DC. Thakral, M., Leveille, S. G., Stuart-Shor, E. M. (2014) A critical analysis of multidimensional pain instruments. (Paper presentation) Eastern Nursing Research Society Annual Meeting, Philadelphia, PA. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2013) Pain quality descriptors in the elder population: The MOBILIZE Boston Study. (Symposium presentation) Gerontological Society of America Annual Meeting, New Orleans, LA. Thakral, M., Shi, L., Shmerling, R. H., Bean, J. F., Leveille, S. G. (2013) Prevalence and characteristics of pain qualities in older adults with chronic pain. (Poster) Eastern Nursing Research Society Annual Meeting, Boston, MA. Thakral, M., Shmerling, R. H., Bean, J. F., and Leveille, S. G. (2012). A stiff price to pay: Joint stiffness and disability in an older population. (Poster) Eastern Nursing Research Society Annual Meeting, New Haven, CT. Thakral, M., Shmerling, R. H., Bean, J. F., and Leveille, S. G. (2012). A stiff price to pay: Does joint stiffness predict disability in an older population? (Poster) Gerontological Society of America Annual Meeting, San Diego, CA. CLINICAL PRESENTATIONS Thakral, M. & Kishore, P. (2010). The Massachusetts model: Primary care nurse practitioners as the M. Thakral Page 4

agent of change in treatment of alcohol and drug dependence. (Poster) National Conference of Nurse Practitioners, Chicago, IL. Thakral, M. & Plummer, P. (2011). Sexuality and intimacy. (Symposium presentation) New England Spina Bifida Conference, Sturbridge, MA. Thakral, M. & Plummer, P. (2009-2011). Transition issues for youth with disabilities and their families. (Symposium presentation) Annual Disabilities Interclerkship, at the University of MA Medical School. Thakral, M., (2009). Common medical problems of the addicted patient. Medical Grand Rounds Presentation, University of Massachusetts Memorial Medical Center, Worcester, MA. Thakral, M., (2008). Commencement Address for the Leadership Education in Neurodevelopmental and Related Disabilities Fellowship Program at the University of Massachusetts Medical School, Waltham, MA. Thakral, M. & Plummer, P. (2007). Health and healthy living for transitioning adolescents with disabilities. (Symposium presentation) Massachusetts Consortium for Children with Special Health Care Needs Annual Meeting. Thakral, M. (2007). Sharing their story: How to help youth with special healthcare needs manage healthcare, education, employment and independent living. (Symposium presentation) MA and NH Regional Medical Home Learning Session, sponsored by Central MA Medical Home Network Initiative. Thakral, M. (2006) Living and learning with a disability. Kenneth B. Schwartz Center Educational Rounds, MGH Institute of Health Professions, Charlestown, MA. HONORS Carol A. Lindeman Award for New Researchers 2017 Anne Kibrick Award for Scholarly and Scientific Achievement 2015 Association on Higher Education and Disability Scholarship 2008 Professional Nurse Traineeship Award 2007-2008 Sigma Theta Tau Nursing Honor Society 2006-current Judith Fong Bressler Nursing Scholarship 2006 PROFESSIONAL AFFILIATIONS American Nurses Association Sigma Theta Tau International American Academy of Nurse Practitioners Gerontological Society of America National Organization of Nurses with Disabilities Western Institute of Nursing M. Thakral Page 5

Member of the Executive Board of Directors for Partners for Youth with Disabilities, Boston, MA M. Thakral Page 6