Inflammatory Bowel Disease

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New Advances in Inflammatory September 6-7, 2014 Hilton San Diego Resort San Diego, California conference highlights Plenary talks from industry leading experts Extended question and answer time with expert faculty Interactive case presentations and discussion Endoscopic video learning sessions Endorsed by the AGA Institute Endorsed by Nursing and patient education track A mobile app will provide you with access to conference course materials from the convenience of your mobile device or computer Visit www.scripps.org/ibdcme for conference updates! Follow the conversation on Twitter at #ScrippsUCSDIBD

course information overview Crohn s disease and ulcerative colitis, collectively known as Inflammatory (IBD), are considered chronic and lifelong conditions that are characterized by alternating periods of active symptomatic disease and periods of remission. IBD is one of the five most prevalent gastrointestinal disease burdens in the United States, with an overall health care cost of more than $1.7 billion and it is estimated that more than one million people in the United States are affected by the disease. Because IBD is a lifelong condition, the importance of establishing and maintaining symptom control and remission is critical to minimizing complications. The treatment of active IBD has improved considerably, but a high rate of relapse is still associated with the disease, and maintaining remission can prove challenging to providers. The New Advances in Inflammatory conference will highlight the latest concepts in the diagnosis and treatment of IBD. Disease complications, social and psychological side effects, special population considerations, and surgical options will also be discussed. The course will be taught by nationally known experts who are actively involved in clinical trials and studies related to the management of Crohn s and colitis. Physicians will be provided with the necessary context to integrate the relevant information into their practices to improve the quality of life for their afflicted patients. target audience This course is designed for gastroenterologists, gastroenterology nurses, internists, colorectal surgeons and allied health professionals involved in the care of patients with Inflammatory (IBD). educational objectives After attending this activity, participants should be able to: Summarize recent clinical trial data regarding the next generation of therapies in inflammatory bowel disease Incorporate new diagnostic methods into practice for inflammatory bowel disease Evaluate current and future treatment and therapy options for inflammatory bowel disease Assess surgical options for the treatment of inflammatory bowel disease Appraise the role of biologics in the treatment of inflammatory bowel disease Recognize the various social and psychological side effects of patients and utilize psychosocial tools in the management of inflammatory bowel disease accreditation & disclosure Accreditation Scripps Health is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Scripps Health designates this live activity for a maximum of 11.75 AMA PRA Category 1 Credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity. California State Board of Registered Nurses Provider approved by the California Board of Registered Nursing, Provider Number CEP15199, for up to 15.3 contact hours. Contact hours will be provided by Scripps Center for Learning & Innovation. American Academy of Physician Assistants (AAPA) The American Academy of Physician Assistants accepts Category 1 credit from AMA PRA Category 1 CME organizations accredited by ACCME. Commercial Support This course is supported, in part, by educational grants from industry, in accordance with ACCME accreditation Standards for Commercial Support. At the time of printing, a complete listing of commercial supporters was not available. Appropriate acknowledgement will be given to all supporters at the time of the educational activity. Cultural and Linguistic Competency This activity is in compliance with California Assembly Bill 1195 which requires that all CME activities comprising a patient care element include curriculum addressing the topic of cultural and linguistic competency. The intent of this bill is to ensure that health care professionals are able to meet the cultural and linguistic concerns of a diverse patient population through effective and appropriate professional development. Cultural and linguistic competency was incorporated into the planning of this activity. Exhibit and Support Opportunities For information on exhibit and support opportunities during this and many other Scripps educational conferences, please contact: Scripps Conference Services & CME 858-652-5400 med.edu@scrippshealth.org www.scripps.org/conferenceservices PATIENT EDUCATION TRACK This two hour comprehensive educational program for patients and families will provide you with the most current medical and surgical approaches to IBD, presented by leading experts. WHO SHOULD ATTEND THE PATIENT EDUCATION TRACK? This activity has been planned for patients and family members affected by inflammatory bowel disease as well as other persons in the healthcare community with an interest in the treatment and management of patients with IBD. To Register for the Patient Education track contact the CCFA Greater San Diego and Desert Area Chapter directly at: Onlinehttp://online.ccfa.org/sd-eduprogram Phone 619-497-1300 E-mail sandiego@ccfa.org about scripps Scripps Health, a nonprofit health care system based in San Diego, California, includes more than 2,600 affiliated physicians and over 13,000 employees at five acute-care hospital campuses, home health care services and a network of clinics, physician offices and outpatient centers. Scripps is committed to contributing to the future of medicine through its clinical research trials, graduate medical education and continuing medical education programs. More information can be found at www.scripps.org. Scripps Conference Services & CME, which offers nationally recognized live conferences in a variety of specialty areas, is committed to improving the quality of health care and advancing the practice of medicine by providing exceptional educational courses for physicians and other health care professionals. More information and conference brochure downloads are available at www.scripps.org/conferenceservices. about uc san diego health system-inflammatory bowel disease center The multidisciplinary specialists in our Inflammatory Center diagnose and treat people with inflammatory bowel disease (IBD) from around the world. Our vision is to continue building and improving our center of learning, while treating inflammatory bowel disease through clinical care, education, and clinical and laboratory research. Our leadership in IBD research means that you have access to clinical trials for the newest therapies and advanced surgical techniques for the treatment of this challenging condition. More information is available at www.health.ucsd.edu/ibd.

faculty COURSE DIRECTORS Walter J. Coyle, MD, FACG, FACP Gastroenterology Division Head Scripps Clinic Barrett G. Levesque, MD Assistant Professor of Clinical Medicine William J. Sandborn, MD, FACG Chief, Division of Gastroenterology Director of IBD Center M. Jonathan Worsey, MD, FRCS (eng.), FACS, FASCRS San Diego Colon and Rectal Surgeons La Jolla, CA HONORARY COURSE DIRECTOR David M. Roseman, MD, FACP, AGAF Former Chief of Staff Scripps Memorial Hospital La Jolla Faculty Disclosure: In accordance with the ACCME Standards for Commercial Support, course directors, planning committees, faculty and all others in control of the educational content of the CME activity must disclose all relevant financial relationships with any commercial interest that they or their spouse/partner may have had within the past 12 months. If an individual refuses to disclose relevant financial relationships, they will be disqualified from being a part of the planning and implementation of this CME activity. Employees of a commercial interest with business lines or products relating to the content of the CME activity will not participate in the planning or any accredited portion of the conference. Disclosure will be made to all participants at the conference location, prior to the educational activity commencement. GUEST FACULTY Ashish Atreja, MD, MPH, FACP Director, I-ROQ (Informatics for Research, Outcomes and Quality) Assistant Professor Division of Gastroenterology Icahn School of Medicine at Mount Sinai New York, New York Niels Vande Casteele, PharmD, PhD Postdoctoral Fellow Geert D Haens, MD, PhD, AGAF Director, Robarts Clinical Trials, Europe and Gastroenterology Inflammatory Centre Academic Medical Centre University of Amsterdam, Netherlands Amsterdam, Netherlands Elisabeth Evans, MSN, FNP-BC Nurse Practitioner William A. Faubion, MD Director, Pediatric IBD Center Associate Professor of Pediatrics & Immunology Associate Mayo Clinic Rochester, Minnesota Brian G. Feagan, MD, FRCPC Epidemiology & Biostatistics University of Western Ontario London, Ontario, Canada Sahil Khanna, MBBS Gastroenterologist Assistant Mayo Clinic Rochester, Minnesota Ralf Kiesslich, MD, PhD St. Mary s Hospital Frankfurt, Germany Gauree G. Konijeti, MD, MPH Gastroenterology & Hepatology Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts Jonathan A. Leighton, MD, FACG, AGAF Chair of the Division of Gastroenterology Mayo Clinic College of Medicine Scottsdale, Arizona James D. Lewis, MD, MSCE and Epidemiology Senior Fellow Leonard Davis Institute of Health Economics Senior Scholar Center for Clinical Epidemiology and Biostatistics Associate Director Inflammatory Program University of Pennsylvania Philadelphia, Pennsylvania Gary R. Lichtenstein, MD, FACG University of Pennsylvania School of Medicine Director, Center for Inflammatory Division of Gastroenterology Philadelphia, Pennsylvania Robert Madoff, MD, FACS, FASCRS Professor of Surgery Chief, Division of Colon & Rectal Surgeon University of Minnesota Minneapolis, Minnesota Marci Reiss, LCSW Founder & President IBD Support Foundation Los Angeles, California Florian Rieder, MD Department of Gastroenterology, Hepatology & Nutrition Digestive Disease Institute Cleveland Clinic Cleveland, Ohio Jesús Rivera-Nieves, MD Associate James T. Rosenbaum, MD Director of Inflammatory Research Division Chief of Arthritis and Rheumatic Diseases Oregon Health & Science University Portland, Oregon Cynthia Santillan, MD Associate Clinical Professor Vice Chief of Body Imaging Chief of Body CT William J. Tremaine, MD, FACG, AGAF Department of Gastroenterology and Hepatology Mayo Clinic Rochester, Minnesota conference location & hotel information HILTON SAN DIEGO RESORT 1775 E. Mission Bay Drive Reservations: 800-445-8667 San Diego, California 92109 Hotel Direct: 619-276-4010 The Hilton San Diego Resort offers impeccably appointed rooms on an 18-acre bay front park. Enjoy lush gardens, rolling lawns and sandy bay fronts just steps from your door. Conveniently located within easy access of popular attractions such as the San Diego Bay, historic Old Town, the bustling Gaslamp District downtown, the aquatic marvels of Sea World and the world renowned San Diego Zoo, the Hilton San Diego Resort offers visitors a perfect taste of San Diego. We are fortunate to have obtained special low rates at the hotel starting at $219 per night (plus tax). This low rate also includes: No resort fee Complimentary guestroom internet service Complimentary daytime parking Complimentary use of the fitness center Discounted overnight parking at the rate of $20 Make your reservations early! A block of rooms is being held for Scripps until Friday, August 15, 2014. After Friday, August 15, 2014 reservations will be accepted on a space and rate availability basis only. Please make your own reservations and be sure to mention the Scripps IBD conference to receive the reduced rate and conference amenities listed above. Please note: Attendees who book their room through an online, third-party service (Hotels.com, Expedia.com, Priceline.com, etc.) are not eligible to receive the amenities listed above.

program SATURDAY, SEPTEMBER 6, 2014 7 a.m. Registration, Breakfast & View Exhibits 7:55 a.m. Welcome & Introductions 8 a.m. Leukocyte Adhesion and Trafficking: Alpha 4 Integrin Science Jesús Rivera-Nieves, MD 8:30 a.m. Vedolizumab and Other Anti-Integrin Agents for the Treatment of Inflammatory Brian G. Feagan, MD, FRCPC 9 a.m. Treat to Target: What is it and How to do it? Barrett G. Levesque, MD 9:30 a.m. Q&A / Panel Discussion 9:45 a.m. Break & View Exhibits 10:15 a.m. TNF-Anatagonist Pharmacokinetics: Applying Theory to Clinical Practice Niels Vande Casteele, PharmD, PhD 10:45 a.m. Anti-TNF Therapy for Ulcerative Colitis: Which Drug for Which Patients, and What Can We Accomplish? William J. Sandborn MD, FACG 11:15 a.m. Biomarkers in IBD: Which Ones to Use in What Circumstances? Geert D Haens, MD, PhD, AGAF 11:45 a.m. Q&A / Panel Discussion Noon Lunch 1 p.m. Radiology Learning Session: Strictures in IBD Florian Rieder, MD Cynthia Santillan, MD 1:30 p.m. Inflammatory in Teenage Patients William A. Faubion, MD 2 p.m. Endoscopic Video Learning Session: Single and Double Balloon Endoscopy and Capsule Endoscopy Jonathan A. Leighton, MD, FACG, AGAF 2:30 p.m. Endoscopic Video Learning Session: Indeterminate Colitis William J. Tremaine, MD, FACG, AGAF 3 p.m. Break & View Exhibits 3:30 p.m. Eye Findings in Inflammatory : Uveitis, and Steroid Associated Cataracts and Glaucoma James T. Rosenbaum, MD 4 p.m. The Role of Psychosocial Care in Achieving ACA s Triple Aim Marci Reiss, LCSW 4:30 p.m. Case Presentations Walter Coyle, MD, FACG, FACP Robert D. Madoff, MD, FACS, FASCRS M. Jonathan Worsey, MD, FRCS (eng.), FACS 5:30 p.m. Adjourn Inflammatory Nursing Education Lunch 12 p.m. FAQ s for RNs in Inflammatory Elisabeth Evans, MSN, FNP-BC 12:30 p.m. Round Table Discussion Inflammatory Patient Education Track 1 p.m. What to do with Biomarkers? Geert D Haens, MD, PhD, AGAF 1:30 p.m. Testing in Inflammatory : When and How Gauree G. Konijeti, MD, MPH 2 p.m. New Approaches to Biologic Therapy in Inflammatory TBD 2:30 p.m. Q&A / Panel Discussion 3 p.m. Inflammatory Patient Education Track Adjournment SUNDAY, SEPTEMBER 7, 2014 7:30 a.m. Registration, Breakfast, & View Exhibits 8 a.m. Endoscopic Video Learning Session: Chromoendoscopy Ralf Kiesslich, MD, PhD 8:30 a.m. Replacement Therapies in Inflammatory Bowel Disease: What are the Options for Iron, Vitamin B12, and Vitamin D? Gary R. Lichtenstein, MD, FACG 9 a.m. Nutritional Therapy for Crohn s Disease James D. Lewis, MD, MSCE 9:30 a.m. Q&A / Panel Discussion 9:45 a.m. Break & View Exhibits 10 a.m. Electronic Health Record and Inflammatory Ashish Atreja, MD, MPH, FACP 10:30 a.m. Microscopic Colitis Sahil Khanna, MBBS 11 a.m. Surgery & Inflammatory Robert Madoff, MD 11:30 a.m. Gastroenterology/Colorectal Surgeon Case Presentations & Panel Walter Coyle, MD, FACG, FACP Gauree G. Konijeti, MD, MPH Robert D. Madoff, MD, FACS, FASCRS M. Jonathan Worsey, MD, FRCS (eng.), FACS 12:30 p.m. Final Adjournment

New Advances ininflammatory September 6 7, 2014 Hilton San Diego Resort San Diego, California CONFERENCE FEES Space is limited, so register early! Included: Course tuition, access to conference materials (via mobile app and conference website) breakfast, breaks and lunch (Saturday Only). Not Included: Travel costs, lodging, parking, and dinners 1. Main Conference Thru May 31 June 1 - Sept 3 On-site After Sept 3 Physicians $255 $280 $305 Nurses/Nurse Practitioners/ $195 $220 $245 Physician Assistants/ Allied Health Professionals Fellows & Residents $135 $160 $185 2. Nursing Education Lunch (Space is limited- no additional fee) Yes, I would like to attend the Nursing Education Lunch 3. Patient Education Track To register for the Patient Education track contact the $10 CCFA Greater San Diego and Desert Area Chapter directly at: Online http://online.ccfa.org/sd-eduprogram Phone 619-497-1300 E-mail sandiego@ccfa.org Please note: There are no day rates available for this conference. By completing this registration form and returning it to Scripps you are acknowledging compliance with all attendance policies. Would you like to receive the Scripps Conference Services & CME email newsletter? Yes No Please print clearly. Should we have any conference communications or updates please provide your direct contact information. FIRST, MI, LAST NAME AFFILIATION/HOSPITAL/COMPANY DIRECT MAILING ADDRESS CITY/STATE/ZIP CELL OFFICE PHONE 9 PLEASE INDICATE ANY SPECIAL NEEDS (INCLUDING DIETARY RESTRICTIONS): Special requests will be considered and accommodated in full compliance with the Americans with Disabilities Act (ADA). Office Use Only: Date Received Amount Check No. / Approval CD Confirmation Sent Initials PAYMENT METHOD Check Please make checks payable to Scripps (in U.S. dollars only). Visa MasterCard Amex Discover If paying by credit card, please complete the information below. C REDIT CARD NUMBER NAME ON CARD BILLING ADDRESS IF DIFFERENT FROM ABOVE FAX DEGREE (MD, DO, PHD, RN, ETC) SPECIALTY E-MAIL (THIS IS REQUIRED AND WILL BE YOUR USER NAME WHEN ACCESSING YOUR ONLINE ACCOUNT.) EXPIRATION DATE SECURITY CODE ON CARD (REQUIRED) Three Easy Ways to Register Online www.scripps.org/ibdcme Fax 858-652-5565 Mail Scripps Conference Services & CME IBD Conference 11025 North Torrey Pines Rd. Suite 200, Maildrop: SCRC 200 92037 Questions Contact Scripps Conference Services & CME Phone 858-652-5400 Email med.edu@scrippshealth.org Attendance Policies Registration Confirmation A confirmation letter will be e-mailed or mailed to you upon receipt of the conference registration form and payment. If you have not received it within two weeks, please contact the Scripps Conference Services & CME office. Attendee Cancellation, Substitution, Refund The course tuition is refundable, minus a $75 processing fee ($50 for Fellows/Residents), if your cancellation is received in writing no later than Friday, August 29, 2014. Attendee substitutions are allowed, but notification must be made in writing by Friday, August 29, 2014. After this date, under no circumstances will refunds, credits, or substitutions be granted. No refunds or credits will be given to no shows. Guest Attendance Policy All conference activities (including educational sessions, meal functions, exhibit hall, etc.) are exclusively reserved for conference attendees. Non-registered guests (including children, family members, colleagues, etc.) are not allowed in the conference areas. Badges provided at registration are required for entrance into all functions and will be strictly enforced. Scripps Conference Modification or Cancellation Scripps reserves the right to modify the course s schedule or program as necessary. Scripps also reserves the right to cancel this conference, in which case a full refund of the registration fee will be provided. We are unable to refund any travel costs (flight, hotel, etc.) in the case of Scripps cancellation. Recording and Photography Clause Scripps reserves exclusive rights to record (audio and video) and/or photograph all conference proceedings for use in marketing materials, presentations and course content sales. AUTHORIZED SIGNATURE

Scripps Conference Services & CME 11025 N. Torrey Pines Road Suite 200, Maildrop: SCRC 200 92037 New Advances in Inflammatory September 6-7, 2014 Hilton San Diego Resort San Diego, California f o l l o w u s! www.facebook.com/scrippscme www.twitter.com/scrippscme www.youtube.com/scrippshealth New Advances in Inflammatory DOWNLOAD THE SCRIPPS CME APP FOR YOUR SMART PHONE OR TABLET! All conference information including a detailed agenda, faculty listing, faculty disclosures, industry support, attendee list, and course materials can be found on the free Scripps CME conference app for iphone, ipad, Android, and BlackBerry. To download the app on your smart phone or other device visit the appropriate app store and search ScrippsCME (must be one word) or scan the appropriate QR code below. The app is free of charge and will be continuously updated during and after the course. Please note there will NOT be a printed syllabus available at the conference. All materials will be accessible through the conference app. SCAN THESE QR CODES Blackberry iphone Android Storm and Torch To access using your cell phone or computer s web browser: http://www.grupio.com/scrippscme