PPI Deprescribing: Ascension

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PPI Deprescribing: Ascension Tonya Thomas, PharmD Clinical Pharmacist Saint Thomas West Hospital Nashville, TN, USA #derx2018 Session resources will be available at deprescribing.org/resources

Learning Objectives Describe the necessary support structure for a deprescribing initiative Identify strategies for successful implementation of a deprescribing initiative Explain the key learning points in the implementation process

Deprescribing Initiative: Process Map Determine team leaders and stakeholders Define AIM statement Create Driver Diagram Identify Intervention Strategies Measure Outcomes

Ascension PPI Deprescribing: Key System Stakeholders David Pryor, MD John Pirolo, MD Executive Vice President Senior Vice President Chief Clinical Officer, Ascension Chief Medical Information Officer, Ascension Local Stakeholders engaged for each site: Physician Champion Pharmacist Champion Informatics Champion

Ascension PPI Deprescribing: Team Leaders Day-to-Day Leader Patrick Leinauer, PMP Program Manager Senior Leader/Sponsor Clinical Champion(s) Ann Hendrich, PhD, RN, FAAN Karen Smethers, PharmD Senior Vice President of Quality and Safety Executive Director of the Ascension Health Patient Safety Organization (PSO) Chief Nursing Officer Director, Clinical Services Kevin Grady, MD Chief Medical Officer St John Providence Medical Center Said Soubra, MD Chief Medical Officer Seton Medical Center, Williamson Gregory James, MD Chief Clinical Officer Saint Thomas Health Informatics Team Lead Dan Leffler, DPh, MS Senior Director, Pharmacy Information Systems

Ascension PPI Deprescribing: Team Leaders On Site Leaders Leanne Phillips PharmD, BCPS Clinical Pharmacy Coordinator, St. Vincent s East Ascension Tamara Knight PharmD, BCPS Network Clinical Pharmacy Specialist Internal Medicine Seton Healthcare Family DeeDee Hu PharmD, BCPS Network Clinical Pharmacy Specialist Critical Care Seton Healthcare Family Tonya Thomas PharmD Clinical Pharmacist Saint Thomas West Hospital

Ascension PPI Deprescribing: AIM Statement By July 2018, reduce the use of Proton Pump Inhibitors by 50% in adult patients at three Ascension pilot sites.

PPI Deprescribing: Ascension Proton Pump Inhibitor Therapy De-Prescribing In the inpatient health-system setting St. Thomas West Seton Healthcare Family St. Vincent s East Nashville, TN Austin, TX Birmingham, AL Three pilot sites that joined the initiative in June 2017

Ascension PPI Deprescribing: Driver Diagram Primary Drivers Secondary Drivers Change Ideas Identification of people (patients) receiving targeted medication(s) Use of EB algorithm in development of deprescribing Clinical decision support tools on admission transfer and discharge to identify eligible patients (Programming of electronic alerts to identify patients through E.H.R. and Sentri7 application), CPOE, RPh on rounds, Med rec vs dlc Approach derx'g as reduce or stop Evidence based protocols and algorithms for de-rx and weaning Standard and simplified work aids Team approach (MD, RPh, RN, RN Educators,Informatics specialists) Develop single page algorithm work aids for derx'g By July 2018, reduce the use of Proton Pump Inhibitors by 50% in adult patients at three Ascension pilot sites. Clinician and Patient and family engagement Programming, CDS Identify indication for use for PPI Patient/Family Education Designate physician and clinical pharmacist as team leaders Use multiprofessional team to develop project and work with families on derx'g Listen to patients and family to ascertain values and preferences on medications in their life and derx'g Confirm team's understanding of derx'g goals with family and patients. Engage front line staff and trusted staff to discuss derx'g with family and patient Routine Monitoring and Reflection among Teams and Sites Frank discussions of how things are going and what needs improvement Stress safety and advantages of approach to stop and/or de-escalation Use teach back and motivational interviewing techniques Offer safety and key learning points as handouts to support Coaching Calls Provider Education Review outcomes with unified metrics Monitor data routinely together (standardize and compare) Ask and reflect on how the process is going: what is moving along as planned, where are our predictions different from what is emerging; what are we learning; what surprises us? What are uniquely situated constraints to process?

Ascension PPI Deprescribing: Implementation Strategies Healthcare Professional Education Indications Criteria for Use Adverse Effects Removal of PPI from order sets Clinical Decision Support Sentri 7 monitoring Order entry Alert PRN order frequency

Ascension PPI Deprescribing: Sentri 7 Alert Identification of all PPI orders Intravenous PO

Ascension PPI Deprescribing: Order Alert Requires documentation of medical indication for PPI therapy

Ascension PPI Deprescribing Strategy Timeline TX Edu TN CDS Re education -- ALL TX CDS IHI LS3 -- ALL TN Edu AL CDS AL Edu Nov-16 Mar-17 Jun-17 Sep-17 Dec-17 Apr-18 Jul-18

Days of Therapy Per 1000 Patient Days Days of Therapy Per 1000 Patient Days Ascension 2000 1800 1600 1400 1200 1000 800 600 400 200 0 JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC JAN Month Seton Saint Thomas

Ascension: Implementation Strategies Successes Order Entry Alert Sentri 7 Alert Deprescribing as a culture Setbacks PRN PPI indication Pilot sites within a health system Conversion of Electronic Medical Records (Upgrade) Prescriptive habits perpetual education Key Learning Points Identification of key stakeholders and leadership for support and success Consistent measure and communication of current status to maintain engagement Education as a foundation for change