Newsletter. Letter from the president. Spring Inside this issue: Yi Jin, PhD, DABT AACT President. Dear AACT Members,

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Dear AACT Members, We are quickly approaching the time of the year for AACT members to gather at the annual SOT conference. Sunshine in San Diego could not be a better excuse for each of us to take a break. In the last couple months, AACT board members have been actively working on several AACT Committees 5 agendas. The Award committee led by Sherwin Yan has completed the process of 4 th Annual Meeting of nomination, evaluation and finalization on various AACT awards, including Distinguished Drug Toxicology, China 5 Chinese Toxicologist Lectureship Award, Jean Lu Student Scholarship Award, and Best Abstract awards. Each of these awards represents the AACT objectives for recognizing outstanding Chinese toxicologists from all the toxicology fields. I invite you to attend the lectureship presentation to be held on Monday, March 23th, at 5:00 pm at the Marriott Hotel, which will then be followed by the annual AACT business meeting and reception Our sponsors 6 This year for the first time, we have planned two career workshops for our members: one focused on the US job market for toxicologists and the second on opportunities in China for toxicologists. Victoria Tu and Gene Hsu have led the effort. Career workshops have become a main attraction for our members in recent years. In the last three years, attendees for each of the three annual career workshops exceeded our expectations. Last year, we had more than 80 people attend the workshop, one of the most successful events for AACT. Attendees included not only graduates and young toxicologists but also many seasoned toxicologists. The workshop provided an ideal platform for exchanging job information and work experiences at different industries or different job levels. China has become a new emerging place attracting many returnees. I am included in this category, having returned to China last year. Many people eagerly want to know what is going on in China for toxicologists. This time, we are specifically holding a workshop focused on the China market. We have invited a few returnees who have been working at Chinese CROs or multinational pharmaceutical companies to share their experiences with us. We have just completed this annual AACT board election with newly elected President-elect, two new councilors, and one new student representative. AACT board members have been rotating yearly, which provides wonderful opportunities for our members to be involved with the organization and to serve members. The finance committee led by Ping Peng has been working very hard to seek sponsorships from various organizations. Last year, we made a record in fund-raising, making it challenging this year to match last year s amount. I encourage each of our members to promote AACT through your personal network and seek sponsorships from your company. It is crucial for AACT to obtain adequate funding in order to uphold its missions and objectives. Finally, I hope to see you all at our annual meeting and reception on Monday evening at 6:00-8:00PM. Let s have good time for fun and our friendship. This is a once a year gathering and celebration, don t miss it! Sincerely, Yi Jin, PhD, DABT AACT President Newsletter Spring 2015 Letter from the president Inside this issue: President letter 1 Announcements 2 2015 AACT awards 3 New AACT officers 4 Page 1

Page 2 See you in 2015 SOT Annual Meeting at San Diego, CA! 2015 AACT Distinguished Chinese Toxicologist Lectureship Presentation Dr. Qin M. Chen Professor of Pharmacology University of Arizona College of Medicine Lecture title: Translational Control of Oxidative Stress Time: Monday, March 23, 2015, 5:00 pm to 6:00 pm Location: Marriott Marquis, San Diego Ballroom B and C 2015 AACT Annual Business Meeting and Reception Time: Monday, March 23, 2015, 6:00 pm to 8:00 pm Location: Marriott Marquis, San Diego Ballroom B and C 2015 AACT/KTAA Career Workshop 1 Title Current US Job Market for Toxicologists Chair: Victoria Tu (Revlon, Inc) Speakers: Jack Yao (US FDA) Matt Liu (Regeneron Pharmaceuticals, Inc) Sophie Jia (Chevlon Philips Chemical Company) Time: Tuesday, March 24, 2015 7:30-9:00AM Location: Convention Center, Room 3 Breakfast will be served. 2015 AACT Career Workshop 2 Title Opportunities for Toxicologists in China Chair: Gene Hsu (HEC Pharma Group, China) Speakers: James Yan (Covance China) Yi Yang (Sanofi China) YZ Zhang (GSK China) Yi Jin (Wuxi AppTec) Time: Tuesday, March 24, 2015, 12:00-1:30PM Location: Convention Center, Room 3 A box of lunch will be provided.

Page 3 Congratulations to the 2015 AACT Award Recipients! Distinguished Chinese Toxicologist Lectureship Award Jean Lu Student Scholarship Award Dr. Qin M. Chen Professor of Pharmacology College of Medicine University of Arizona Marlene T. Kim Department of Chemistry Rutgers University Charles River Best Abstracts Award Winners 1st Place Heidi Hsieh University of Cincinnati 2nd Place Zhoumeng Lin Kansas State University 3rd Place Rui Yu University of North Carolina at Chapel Hill

Page 4 Congratulations to the Newly Elected AACT Officers! President-Elect Hannah Ng SRI Biosciences Councilor Robert Li Genentech Councilor Zemin Wang Indiana University Student Representative Jinpeng Li Michigan State University

Page 5 AACT Officers (2014-2015) President: Yi Jin President-Elect: Ching-Hung (Gene) Hsu Secretary: Sherwin Yan Treasurer: Ping Peng Immediate Past President: Edward Chow Councilor: Xuefeng Ren Councilor: Victoria Tu Postdoc Rep: Qiangen Wu (Newsletter editor) Student Rep: Kathy S. Xue (Newsletter editor) AACT Officers (2015-2016) President: Ching-Hung (Gene) Hsu President-Elect: Hanna Ng Secretary: Xuefeng Ren Treasurer: Victoria Tu Immediate Past President: Yi Jin Councilor: Zemin Wang Councilor: Robert Li Postdoc Rep: Qiangen Wu (Newsletter editor) Student Rep: Jinpeng Li (Newsletter editor) AACT Committees (2014-2015) Finance Committee: Ping Peng Program Committee: Gene and Victoria Nomination/Election Committee: Ed Chow Membership Committee: Gene Hsu ICTF: Ed and Gene Award Committee: Sherwin Yan The 4 th Annual Meeting of Drug Toxicology, China The 4 th Annual Meeting of Drug Toxicology was held last October at Kunming, China. Around 600 representatives came from a total of 51 various research institutions, companies and universities, with a total of 378 presentations and abstracts. During the first and the last half day, there were 18 plenary speeches covering topics including progress and the development of the new chemical drugs, risk management and control for traditional Chinese medicine and biotechnology drug development, research progress toxicity biomarkers, Chinese GLP laboratory situation, etc. During the 2 nd and 3 rd day, the meeting broke into four symposium sessions of general toxicity, safety pharmacology and drug pharmacokinetics, CMR and associated mechanisms and quality assurance. This meeting witnessed years of hardship and difficulty in development of drug toxicology in China, but more clearly seen was the tremendous progress in research in anticancer drugs targeted therapy, transgenic and humanized animal model, application of stem cells culture in vitro, toxicokinetics and pharmacokinetics, clinical biomarkers for liver, kidney and cardiac toxicity and GLP quality assurance. AACT representatives Yi Jin, Joe Zhang and Zhengyu Yin presented at the meeting. Yi gave a plenary speech on Application of transgenic animals in cancer studies. Other AACT members attending the meeting include Gene Hsu, Charles Wang, James Yan, Jack Xie etc. They had deep discussion and exchanged ideas with other toxicologists. The 5 th Annual Meeting of Drug Toxicology (China) will be held on June 29 to July 2 nd at Haikou, in Hainan Island. (by Zhengyu Yin)

Page 6 Many Thanks to Our AACT Sponsors! Please Support AACT! Through Individual/Company Sponsorship or Award Fund (SOT Endowment Fund) How to join AACT To join AACT and SOT, please go to: http://www.toxicology.org/isot/sig/aact/join.asp