Nutritional Immunology and the Microbiota: Rules of Engagement in Health & Disease June 24 29, Leesburg, VA

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Nutritional Immunology and the Microbiota: Rules of Engagement in Health & Disease June 24 29, 2018 Leesburg, VA Organizers: Margherita T. Cantorna, Ph.D., Distinguished Professor of Molecular Immunology Department of Veterinary and Biomedical Sciences, Pennsylvania State University University Park, PA Charles B. Stephensen, Ph.D., Research Leader and Adjunct Professor Immunity and Disease Prevention Research Unit, USDA Western Human Nutrition Research Center; and Nutrition Department, University of California, Davis Davis, CA Sunday, June 24, 2018 Time 4:00 p.m. 9:00 p.m. Conference Registration 5:00 p.m. 6:00 p.m. Welcome Reception 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 8:00 p.m. Keynote Speaker Yasmine Belkaid, NIAID/DIR, Mucosal Immunology Section. Control of tissue immunity by nutritional microbiota cross talk. 8:00 p.m. 9:30 p.m. Meet the Experts Roundtable To Include several Program Officers Chair, Charles Stephenson and Margherita Cantorna Monday, June 25, 2018 Time 7:30 a.m. 1:00 p.m., Conference Registration 4:00 p.m. 6:00 p.m. 9:00 a.m. 12:00 p.m. Scientific Session SESSION 1: DIET, MICROBIOTA AND IMMUNITY IN INFANCY Speaker 1 and Chair Sharon Donovan, University of Illinois, Champaign Urbana, IL USA Impact of early gut microbiota on immune development Speaker 2 David A. Mills, University of

10:00 a.m. 10:15 a.m. FASEB Sponsored Coffee Break California, Davis, CA, USA Breast milk and the establishment of the infant microbial community Speaker 3 Andreas Baumler, University of California, Davis, CA USA Host mediated sugar oxidation promotes post antibiotic pathogen expansion Speaker 4 Michael Zimmermann Swiss Federal Institute of Technology, Zurich Switzerland TBD

12:00 p.m. 1:00 p.m. LUNCH and Networking session #1 at lunch Meet the Experts Session 1:00 p.m. 4:00 p.m. Free time 4:00 p.m. 6:00 p.m. Scientific Session SESSION 2: NUTRITIONAL CONTROL OF TOLERANCE Chair Sarah Comstack, Michigan State University Early Stage investigator Speaker 1 Philip Calder, University of Southampton, Southampton England UK Omega 3 fatty acids and immune programming Speaker 2 Charles Stephensen, University of California, Davis, California USA Gut microbiota and the vaccine responses in healthy infants in Dhaka, Bangladesh Speaker 3 Cathryn Nagler, University of Chicago, Chicago, IL USA Microbial control of food allergy Speaker 4 William DePaolo, Univeristy of Washington, Seattle WA USA 6:00 p.m. 7:00 p.m. Conference Registration 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 9:00 p.m. Poster Session Tuesday, June 26, 2018 Time 7:30 a.m. 1:00 p.m., Conference Registration 4:00 p.m. 6:00 p.m. Scientific Session SESSION 3: DIET, PROBIOTICS, MICROBIOTA AND IMMUNITY Chair Margherita T. Cantorna, Pennsylvania State University, University Park, PA USA. Nutrient regulation of the microbiome and immunity to maintain gastrointestinal homeostasis Speaker 1 Xin Luo, Virgina Tech, Blackburn, VA USA Probiotics, the microbiota and lupus Speaker 2 Prosper Boyaka, Ohio State University, Columbus, OH USA. TBD abstracts: Travel awardee Speaker 3 Charles Mackay, Monash University,

Victoria, Australia Dietary fiber, bacterial short chain fatty acids and immune function Speaker 4 Bobbi Langkamp Henken, University of Florida, Gainesville, FL USA Probiotics and allergy related quality of life? 10:00 a.m. 10:30 a.m. FASEB Sponsored Coffee Break and *Group Photo 12:00 p.m. 1:00 p.m. LUNCH and Networking session #2 Meet the Experts Session 1:00 p.m. 4:00 p.m. Free time 4:00 p.m. 6:00 p.m. Scientific Session SESSION 4: NUTRIENT REGULATION OF IMMUNE FUNCTION Chair Connie Rogers, Pennsylvania State University, University Park, PA USA. Speaker 1 Lothar Rink, RWTH Aachen University, Aachen Germany TBD Speaker 2 Simin Nikbin Meydani, Tufts University, Boston MA USA Vitamin E, ceramides and T cell signaling abstracts: Travel awardee Speaker 3 Robert Chapkin, Texas A&M Omega 3 fatty acids, lipid rafts, and T cell signaling Speaker 4 Connie Rogers, Pennsylvania State University, University Park, PA USA. Role of weight maintenance achieved through calorie restriction and exercise on antigen specific responses 6:00 p.m. 7:00 p.m. Conference Registration 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 9:00 p.m. Poster Session Wednesday, June 27, 2018 Time a.m. Time p.m. 7:30 a.m. 1:00 p.m., Conference Registration 4:00 p.m. 6:00 p.m. 9:00 a.m. 12:00 p.m. Scientific Session SESSION 5: NUTRIENT SENSING IN THE IMMUNE SYSTEM VIA NUCLEAR RECEPTORS Chair Simin Nikbin Meydani, Tufts University, Boston, MA USA Speaker 1 Margherita T Cantorna, Pennsylvania State University, PA USA Vitamin D regulation of

gastrointestinal homeostasis Speaker 2 Adrian Martineau, Barts and the London School of Medicine, London England, UK Immunomodulatory effects of vitamin D on respiratory infection Speaker 3 TBD Speaker 4 Francisco Javier Quintana, Harvard Boston, MA USA AHR regulation of tolerance 10:00 a.m. 10:15 a.m. FASEB Sponsored Coffee Break 12:00 p.m. 12:30 p.m. Business Meeting 12:30 p.m. 1:30 p.m. LUNCH and Networking session #3 Meet the Experts Session 1:30 p.m. 4:00 p.m. Free time 4:00 p.m. 6:00 p.m. Scientific Session SESSION 6: IMMUNOMETABOLISM Chair Brandt Pence, University of Memphis, Memphis, TN USA. Early stage investigator Speaker 1 Peter Murray, Max Planck, Munich, Germany Metabolism and sensing of essential amino acids in immunity Speaker 2 Bali Pulendran, Emory University, Atlanta GA USA Metabolic phenotypes of response to vaccination in humans Speaker 3 Francesca Fallarino, University of Perugia, Perugia, Italy Tryptophan metabolism and regulation of immunity Speaker 4 Tom A Wynn, Pfizer, Boston MA USA Type 2 immunity is protective in metabolic disease 6:00 p.m. 7:00 p.m. Conference Registration 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 9:00 p.m. Poster Session *(confirm the actual day with your Conference Manager)

Thursday, June 28, 2018 Time a.m. Time p.m. 7:30 a.m. 1:00 p.m., Conference Registration 4:00 p.m. 6:00 p.m. 9:00 a.m. 12:00 p.m. Scientific Session SESSION 7: OBESITY, METABOLIC SYNDROME AND INFLAMMATION Chair and Speaker 1 Melinda Beck, University of North Carolina, Chapel Hill, NC USA. Nutrient metabolism and regulation of immunity Speaker 2 Matam Vijay Kumar, Pennsylvania State University, University Park, PA USA. Early stage investigator Interplay between dietary fiber and gut microbiota in metabolic disease Speaker 3 S. Raz Shaikh, University of North Carolina, Chapel Hill, NC USA Obesity impairs B cell responses due to defects in production of n 3 fatty acid derived mediators Speaker 4 Sarah Comstock, Michigan State University, East Lansing MI USA TBD 10:00 a.m. 10:15 a.m. FASEB Sponsored Coffee Break 11:30 a.m. 12:00 p.m. Business Meeting 12:00 p.m. 1:00 p.m. LUNCH and Lunch: Networking session #4 Meet the Experts Session 1:00 p.m. 4:00 p.m. Group Activity (optional) 4:00 p.m. 6:00 p.m. Scientific Session SESSION 8: NUTRIENTS AS COFACTORS IN INFECTION AND IMMUNITY Chair Philip Calder, University of Southampton, Southampton, England, UK. Speaker 1 Sandeep Prabhu, Pennsylvania State University, University Park, PA USA. Selenoproteins and prostaglandins as regulators of immunity Speaker 2 Thomas Ganz, University of California, Los Angeles Hepcidin protects against bacterial infections by preventing the generation of non transferrin bound iron

6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 9:00 p.m. Poster Session (optional) Speaker 3 Miguel Sorres, Gubenkian Institute, Lisbon, Portugal Controlling iron metabolism in disease tolerance Speaker 4 Shipra Vaishnava, Brown University, RI USA Early stage investigator Retinoid and zinc metabolism, and resistance to infection Friday, June 29, 2018 Option 1 Time a.m. Time p.m. 7:30 a.m. 9:00 a.m. Conference Registration 7:30 a.m. 900 a.m. Conference Registration 9:00 a.m. Boxed Snacks to Go and DEPARTURES Option 2 Time a.m. Time p.m. 9:00 a.m. 11:30 a.m. Scientific Session SESSION 9: NUTRITIONAL COST OF INFECTION AND INFLAMMATION Chair and Speaker 1 Kirk Klassing, University of California, Davis, CA USA Nutrition, inflammation and energy metabolism following infection Speaker 2 Rodney Johnson, University of Illinois, Urbana Champaign, IL USA Energy intake during an active immune response: What is the cost? Speaker 3 Lynn B Martin, University of South Florida, Tampa FA USA Nutrient investment strategies in vertebrate evolution: The immune system versus everything else Speaker 4 William Petri, University of Virginia, Charlottesville, VA The effect of childhood infections and intestinal dysbiosis and inflammation on nutritional status and

10:00 a.m. 10:15 a.m. FASEB Sponsored Coffee Break 12:00 p.m. LUNCH to Go and DEPARTURES neurodevelopment in infants or young children END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 www.faseb.org/src