Job Title: Clinical Research Fellow in Dermatology/Skin Scarring Grade: Clinical Job reference: MBP01635 Department: Molecular and Cell Biology Post Responsible To: Principal Investigator Job Purpose: You will be involved in investigating a treatment for scar prevention/reduction in healthy human volunteers and/or laboratory work depending on progress. All work will sought to be published in peer-reviewed journals. You will have the opportunity to undertake work contributing to a higher degree (MD or PhD). Principal Accountabilities: Research You will participate in a clinical research study in the laboratory of Professor Pullar to study the underpinning mechanisms that play a role in skin scarring and fibrosis. % Time 75 Duties will include: Prepare ethics applications Prepare grant applications Recruit healthy volunteers in order to recruit to the study Take informed consent from these volunteers Assessment of patient inclusion/ exclusion criteria Take a medical history and determine Fitzpatrick skin type Perform a medical examination and take blood and urine samples Make 2 cm linear incisions on the inner aspect of each upper arm Treat the incisions with the study drug gel and close with interrupted sutures Photograph the wound and dress it appropriately Take blood samples for PK analysis Record adverse events Assess local tolerability and redose/rephotograph the sites to day 14, then each week to day 28 and monthly thereafter Assess scarring from day 21, day 28 and monthly, thereafter using a range of probes and scar score scales Maintain subject database, liaise with the Leicester Clinical Trials Unit and produce high quality data suitable for publication Data analysis Cell biology and physiology laboratory work depending on progress Write scientific papers, for publication in peer-reviewed journals Version Number: 1 Page 1 of 5 Date of Issue: 12/12/2014
Clinical duties You will be given the opportunity to act up as a dermatology StR. In addition you will be offered a post-graduate training session comprising a weekly ward round, skin cancer MDT, dermatopathology meeting journal club and combined clinic and will have time available for clinical audit linking into the on-going departmental audit programme of CASE approved projects. No on call work will be required. Clinical duties will be negotiated according to level of expertise and interest of the candidate. Dermatological surgery training and service sessions will be made available if required Teaching 20 5 You will also assist in training undergraduates at the University of Leicester Medical School, including the popular and heavily oversubscribed Leicester Medical School Special Study Modules in dermatology and skin cancer. Resources Managed: You will work on high level innovative research projects of great value to the University in terms of financial value, publication in high-impact journals and impact. Internal and External Relationships: The ability to work well in a multidisciplinary team is essential to this post as the post requires frequent and close collaboration with the following: Internal: Members of University staff, including those in the Department of Molecular and Cell Biology The UHL staff including the Dermatology clinical research team, medical and nursing staff, administrative and clerical staff UHL Clinical Research Unit run by Mrs S Batham The Leicester Clinical Trials Unit External: Volunteers attending the University Hospitals of Leicester NHS Trust (including students and staff from the University of Leicester) Members of other Universities/Trusts including collaborative partners NHS patients Planning and Organising: Responsible for directing and managing own work-load to meet the Department s long and short-term objectives and deadlines imposed. Ensure timely analyses for study reports. Recruit volunteers and undertake clinical research studies Plan and perform research on a day to day basis under the supervision of the Principal Investigators Opportunity to register for an MD/PhD, including completion of annual reports and presentation to the higher degrees committee. Version Number: 1 Page 2 of 5 Date of Issue: 12/12/2014
Planning research publications and presentations incorporating own data and that of others up to one year ahead. Qualifications, Knowledge and Experience: Essential MB ChB or equivalent* Full GMC registration* Licence to practice* Completed Core Medical or Surgical Training with evidence of satisfactory outcomes (ARCP level 1) * Demonstrate plans to undertake a future clinical career with an interest in dermatology eg dermatologist, plastic surgeon* Satisfactory enhanced adult DBS disclosure upon appointment Satisfactory OH clearance including Hep B status certificates Good Clinical Practice certificate or ability to obtain IT literate including the ability to use Microsoft Office including Word & Excel, competently, evidenced by previous experience or qualification* Desirable Previous commitment to research evidenced by previous publications, prizes, etc.* Previous research experience e.g. intercalated BSc MRCP (UK) or MRCS or equivalent * Ability to safely perform unsupervised skin biopsies Work to highest standards of probity and good medical practice Dermatological experience clinical or surgical Clinical research experience Experience of writing scientific papers* Previous laboratory experience* Skills, Abilities and Competencies: Essential Must be able to demonstrate behaviours consistent with the University s and Trust s values and behaviours Ability to plan, prioritise and work on own initiative Excellent, fluent oral and written communication skills Desire to learn Motivation and desire to undertake a higher degree Willingness and aptitude to present work at international and national meetings Exceptional organisational, planning and time management skills with the ability to complete work on time and to work to deadlines Self-motivation The ability to interact well intellectually and personally with colleagues and those involved in the research study Statistical knowledge and understanding Enjoyment of working with the general public Enthusiasm for research Version Number: 1 Page 3 of 5 Date of Issue: 12/12/2014
Flexible attitude to work Exceptional analytical and judgement skills Excellent team working skills *Criteria to be used in shortlisting candidates for interview Contract Information: This is a fixed-term contract for two years and will terminate without further notice from the University on the date stated. This post is required on a temporary basis for a short-term project/piece of work as per the Job Summary. Working hours: This is a full-time appointment. Additional Information: Disclosure and Barring Service This post is exempt from the Rehabilitation of Offenders Act 1974 because you will have substantial access to young people and/or vulnerable adults. An appointment to this post will be subject to checking through the Disclosure and Barring Service (DBS). You will be required to give consent for the University to check with the DBS for the existence and content of any criminal record in the form of an Enhanced Disclosure. Information received from the DBS and the police will be kept in strict confidence and will be destroyed once the University is satisfied in this regard. Further information about the DBS is available at: http://www.homeoffice.gov.uk/agencies-public-bodies/dbs/ Athena Swan: We are proud holders of the Athena Swan Bronze Award which recognises and celebrates good employment practice for the advancement of gender equality in higher education and research. The award reflects our commitment to the advancement and promotion of diversity and equality. We are actively seeking Silver and Gold awards. http://www.athenaswan.org.uk Appointment will normally be at the bottom of the scale unless justified otherwise. Version Number: 1 Page 4 of 5 Date of Issue: 12/12/2014
Applications: We use a web based, e-recruitment system, which allows you to apply on-line at: www.le.ac.uk/joinus As part of the online application process, you will be asked to supply contact details for your referees. Please ensure that one of these is your current or most recent employer. You will also be asked to supply a CV and covering letter to support your application. Candidates short-listed for interview will be contacted by the University. If you do not receive a communication from the University within 4 weeks of the closing date, please assume that your application has been unsuccessful. Version Number: 1 Page 5 of 5 Date of Issue: 12/12/2014