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Grant Application Package Opportunity Title: Offering Agency: CFDA Number: CFDA Description: Opportunity Number: Competition ID: Opportunity Open Date: Opportunity Close Date: Agency Contact: Ruth L. Kirschstein National Research Service Award (NRS National Institutes of Health PA-14-147 FORMS-C 03/08/2014 01/07/2017 era Commons Help Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ This opportunity is only open to organizations, applicants who are submitting grant applications on behalf of a company, state, local or tribal government, academia, or other type of organization. Application Filing Name: Studentlast, FI_NRSA Select Forms to Complete Mandatory SF424 (R & R) PHS Fellowship Supplemental Form Research and Related Senior/Key Person Profile (Expanded) Research And Related Other Project Information Project/Performance Site Location(s) Optional Planned Enrollment Report PHS 398 Cumulative Inclusion Enrollment Report Instructions Show Instructions >> This electronic grants application is intended to be used to apply for the specific Federal funding opportunity referenced here. If the Federal funding opportunity listed is not the opportunity for which you want to apply, close this application package by clicking on the "Cancel" button at the top of this screen. You will then need to locate the correct Federal funding opportunity, download its application and then apply.

APPLICATION FOR FEDERAL ASSISTANCE SF 424 (R&R) 3. DATE RECEIVED BY STATE State Application Identifier OMB Number: 4040-0001 Expiration Date: 6/30/2016 1. TYPE OF SUBMISSION 4. a. Federal Identifier IC123456(Resubmissions only) Pre-application Application Changed/Corrected Application b. Agency Routing Identifier 2. DATE SUBMITTED Applicant Identifier Studentlast, FI_NRSA c. Previous Grants.gov Tracking ID GRANT12345678 5. APPLICANT INFORMATION Organizational DUNS: Legal Name: The Regents of the Univ. of Calif., U.C. San Diego Department: Division: Graduate Division 804355790 Street1: 9500 Gilman Drive MC 0003 City: La Jolla County / Parish: San Diego State: CA: California Country: USA: UNITED STATES ZIP / Postal Code: 92093-0003 Person to be contacted on matters involving this application Prefix: First Name: Michelle Middle Name: Ballesteros Last Name: Monroy Suffix: Position/Title: Graduate Fellowship Advisor Street1: 9500 Gilman Drive MC 0003 City: La Jolla County / Parish: San Diego State: CA: California Country: USA: UNITED STATES ZIP / Postal Code: 92093-0003 Phone Number: (858) 822-2938 Fax Number: (858) 534-4304 Email: gradadvisor@ucsd.edu 6. EMPLOYER IDENTIFICATION (EIN) or (TIN): 7. TYPE OF APPLICANT: Other (Specify): 1956006144A1 H: Public/State Controlled Institution of Higher Education Small Business Organization Type Women Owned Socially and Economically Disadvantaged 8. TYPE OF APPLICATION: New Resubmission Renewal Continuation Revision If Revision, mark appropriate box(es). A. Increase Award B. Decrease Award C. Increase Duration D. Decrease Duration E. Other (specify): Is this application being submitted to other agencies? What other Agencies? 9. NAME OF FEDERAL AGENCY: National Institutes of Health 10. CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBER: TITLE: 11. DESCRIPTIVE TITLE OF APPLICANT'S PROJECT: As of May 2014, there is no character limit for this field, and Greek characters are allowed. 12. PROPOSED PROJECT: 13. CONGRESSIONAL DISTRICT OF APPLICANT Start Date Ending Date 09/01/2016 08/31/2021 CA-049

SF 424 (R&R) APPLICATION FOR FEDERAL ASSISTANCE Page 2 14. PROJECT DIRECTOR/PRINCIPAL INVESTIGATOR CONTACT INFORMATION Prefix: First Name: Studentfirst Middle Name: Last Name: Studentlast Suffix: Position/Title: Graduate Student Reseacher Organization Name: The Regents of the Univ. of Calif., U.C. San Diego Department: Studentdepartment Division: General Campus orsom or Skaggs Street1: City: 9500 Gilman Drive MC XXXX(Student department mail code) La Jolla County / Parish: San Diego State: CA: California Country: Phone Number: Email: 15. ESTIMATED PROJECT FUNDING a. Total Federal Funds Requested b. Total n-federal Funds USA: UNITED STATES (858) XXX-XXXX Fax Number: studentemail@ucsd.edu c. Total Federal & n-federal Funds d. Estimated Program Income 17. By signing this application, I certify (1) to the statements contained in the list of certifications* and (2) that the statements herein are true, complete and accurate to the best of my knowledge. I also provide the required assurances * and agree to comply with any resulting terms if I accept an award. I am aware that any false, fictitious. or fraudulent statements or claims may subject me to criminal, civil, or administrative penalties. (U.S. Code, Title 18, Section 1001) I agree *The list of certifications and assurances, or an Internet site where you may obtain this list, is contained in the announcement or agency specific instructions. 18. SFLLL (Disclosure of Lobbying Activities) or other Explanatory Documentation 19. Authorized Representative Prefix: Dr. First Name: Kim Middle Name: Elaine Last Name: Barrett Suffix: Position/Title: Organization: Dean of the Graduate Division The Regents of the Univ. of Calif., U.C. San Diego Department: Division: Graduate Division Street1: 9500 Gilman Drive MC 0003 City: La Jolla County / Parish: San Diego State: CA: California Country: USA: UNITED STATES ZIP / Postal Code: 92093-0003 Phone Number: (858) 534-6655 Fax Number: (858) 534-4304 Email: graduatedean@ucsd.edu Signature of Authorized Representative ZIP / Postal Code: 92093-XXXX (studentdepartment) 16. IS APPLICATION SUBJECT TO REVIEW BY STATE EXECUTIVE ORDER 12372 PROCESS? a. YES THIS PREAPPLICATION/APPLICATION WAS MADE AVAILABLE TO THE STATE EXECUTIVE ORDER 12372 PROCESS FOR REVIEW ON: DATE: b. NO PROGRAM IS NOT COVERED BY E.O. 12372; OR PROGRAM HAS NOT BEEN SELECTED BY STATE FOR REVIEW Date Signed Completed on submission to Grants.gov Completed on submission to Grants.gov 20. Pre-application 21. Cover Letter Attachment

PHS Fellowship Supplemental Form OMB Number: 0925-0001 A. Application Type: From SF424 (R&R) Cover Page. The response provided on that page, regarding the type of application being submitted, is repeated here for your reference as you provide the responses that are appropriate for this Fellowship application. New Resubmission Renewal Continuation Revision B. Research Training Plan 1. Introduction to Application (for RESUBMISSION applications only) 2. * Specific Aims 3. * Research Strategy 4. Progress Report Publication List (for RENEWAL applications only) Human Subjects Please note. The following item is taken from the Research & Related Other Project Information form. The response provided on that page, regarding the involvement of human subjects, is repeated here for your reference as you provide related responses for this Fellowship application. If you wish to change the answer to the item shown below, please do so on the Research & Related Other Project Information form; you will not be able to edit the response here. Are Human Subjects Involved? 5. Human Subjects Involvement Indefinite? 6. Clinical Trial? 7. Agency-Defined Phase III Clinical Trial? 8. Protection of Human Subjects 9. Inclusion of Women and Minorities 10. Inclusion of Children Other Research Training Plan Sections Please note. The following item is taken from the Research & Related Other Project Information form. The response provided on that page, regarding the use of vertebrate animals, is repeated here for your reference as you provide related responses for this Fellowship application. If you wish to change the answer to the item shown below, please do so on the Research & Related Other Project Information form; you will not be able to edit the response here. Are Vertebrate Animals Used? 11. Vertebrate Animals Use Indefinite? 12. Vertebrate Animals 13. Select Agent Research 14. Resource Sharing Plan 15. * Respective Contributions 16. * Selection of Sponsor and Institution 17. * Responsible Conduct of Research

PHS Fellowship Supplemental Form C. Additional Information Human Embryonic Stem Cells 1. * Does the proposed project involve human embryonic stem cells? If the proposed project involves human embryonic stem cells, list below the registration number of the specific cell line(s) from the following list: http://stemcells.nih.gov/research/registry/. Or, if a specific stem cell line cannot be referenced at this time, please check the box indicating that one from the registry will be used: Specific stem cell line cannot be referenced at this time. One from the registry will be used. Cell Line(s): Fellowship Applicant 2. Alternate Phone Number: 3. Degree Sought During Proposed Award: Degree: If "other", please indicate degree type: Expected Completion Date (month/year): Reset Entry 4. * Field of Training for Current Proposal: 5. * Current Or Prior Kirschstein-NRSA Support? If yes, please identify current and prior Kirschstein-NRSA support below: * Level * Type Start Date (if known) End Date (if known) Grant Number (if known) Reset Entry Reset Entry Reset Entry Reset Entry 6. * Applications for Concurrent Support? If yes, please describe in an attached file: 7. * Goals for Fellowship Training and Career 8. * Activities Planned Under This Award 9. Doctoral Dissertation and Other Research Experience 10. * Citizenship: U.S. Citizen or noncitizen national Permanent Resident of U.S. (If a permanent resident of the U.S., a notarized statement must be provided by the time of award) Permanent Resident of U.S. Pending n-u.s. Citizen with temporary U.S. visa

PHS Fellowship Supplemental Form C. Additional Information (continued) Institution 11. Change of Sponsoring Institution Name of Former Institution: D. Sponsor(s) and Co-Sponsor(s) * Sponsor(s) and Co-Sponsor(s) Information E. Budget All Fellowship Applicants: 1. * Tuition and Fees: ne Requested Funds Requested: Year 1 Year 2 Year 3 Year 4 Year 5 14,323.00 15,755.00 17,330.00 19,064.00 20,970.00 Year 6 (when applicable) Total Funds Requested: 87,442.00 Senior Fellowship Applicants Only: Amount Academic Period Number of Months 2. Present Institutional Base Salary: Reset Entry 3. Stipends/Salary During First Year of Proposed Fellowship: Amount a. Federal Stipend Requested: Number of Months b. Supplementation from other sources: Amount Number of Months Type (sabbatical leave, salary, etc.) Source F. Appendix s s s

RESEARCH & RELATED Senior/Key Person Profile (Expanded) OMB Number: 4040-0001 Expiration Date: 6/30/2016 PROFILE - Project Director/Principal Investigator Prefix: * First Name: Studentfirst Middle Name: * Last Name: Studentlast Suffix: Position/Title: Graduate Student Reseacher Department: Studentdepartment Organization Name: The Regents of the Univ. of Calif., U.C. San Diego Division: General Campus orsom or Skaggs * Street1: * City: 9500 Gilman Drive MC XXXX(Student department mail code) La Jolla County/ Parish: San Diego * State: CA: California * Country: USA: UNITED STATES * Zip / Postal Code: 92093-XXXX (studentdepartment) * Phone Number: (858) XXX-XXXX Fax Number: * E-Mail: studentemail@ucsd.edu Credential, e.g., agency login: * Project Role: PD/PI Other Project Role Category: Degree Type: Degree Year: *Attach Biographical Sketch Attach Current & Pending Support PROFILE - Senior/Key Person 1 Prefix: * First Name: Middle Name: * Last Name: Suffix: Position/Title: Department: Organization Name: Division: * Street1: * City: County/ Parish: * State: * Country: USA: UNITED STATES * Zip / Postal Code: * Phone Number: Fax Number: * E-Mail: Credential, e.g., agency login: * Project Role: Other Project Role Category: Degree Type: Degree Year: Attach Biographical Sketch Attach Current & Pending Support Delete Entry Next Person To ensure proper performance of this form; after adding 20 additional Senior/ Key Persons; please save your application, close the Adobe Reader, and reopen it.

RESEARCH & RELATED Other Project Information OMB Number: 4040-0001 Expiration Date: 6/30/2016 1. Are Human Subjects Involved? 1.a. If YES to Human Subjects Is the Project Exempt from Federal regulations? If yes, check appropriate exemption number. If no, is the IRB review Pending? IRB Approval Date: 1 2 3 4 5 6 Human Subject Assurance Number: 2. Are Vertebrate Animals Used? 2.a. If YES to Vertebrate Animals Is the IACUC review Pending? IACUC Approval Date: Animal Welfare Assurance Number: 3. Is proprietary/privileged information included in the application? 4.a. Does this Project Have an Actual or Potential Impact - positive or negative - on the environment? 4.b. If yes, please explain: 4.c. If this project has an actual or potential impact on the environment, has an exemption been authorized or an environmental assessment (EA) or environmental impact statement (EIS) been performed? 4.d. If yes, please explain: 5. Is the research performance site designated, or eligible to be designated, as a historic place? 5.a. If yes, please explain: 6. Does this project involve activities outside of the United States or partnerships with international collaborators? 6.a. If yes, identify countries: 6.b. Optional Explanation: 7. Project Summary/Abstract 8. Project Narrative 9. Bibliography & References Cited 10. Facilities & Other Resources 11. Equipment 12. Other Attachments s s s

Project/Performance Site Location(s) OMB Number: 4040-0010 Expiration Date: 9/30/2016 Project/Performance Site Primary Location I am submitting an application as an individual, and not on behalf of a company, state, local or tribal government, academia, or other type of organization. Organization Name: DUNS Number: * Street1: * City: County: * State: * Country: USA: UNITED STATES * ZIP / Postal Code: * Project/ Performance Site Congressional District: Project/Performance Site Location Organization Name: 1 I am submitting an application as an individual, and not on behalf of a company, state, local or tribal government, academia, or other type of organization. DUNS Number: * Street1: * City: County: * State: * Country: USA: UNITED STATES * ZIP / Postal Code: * Project/ Performance Site Congressional District: Additional Location(s)

OMB Number: 0925-0002 Title of Proposed Application (Item 11, SF424 (R&R)) Domestic Optional t Hispanic or Latino Hispanic or Latino American Indian/ Alaska Native 0 0 0 0 0 Asian 0 0 0 0 0 Native Hawaiian or Other Pacific Islander Black or African American 0 0 0 0 0 0 0 0 0 0 White 0 0 0 0 0 More than One Race 0 0 0 0 0 0 0 0 0 0

OMB Number: 0925-0002 Title of Proposed Application (Item 11, SF424 (R&R)) Optional t Hispanic or Latino Hispanic or Latino Unknown/t Reported Ethnicity American Indian/ Alaska Native 0 0 0 0 0 0 0 0 0 0 Asian 0 0 0 0 0 0 0 0 0 0 Native Hawaiian or Other Pacific Islander Black or African American 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 White 0 0 0 0 0 0 0 0 0 0 More than One Race 0 0 0 0 0 0 0 0 0 0 Unknown or t Reported 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0