Registration Form. Important Dates 3 WAYS TO LEARN March 2010 Luxembourg, Luxembourg

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Registration Form FAMILY NAME GIVEN NAME MI MD PhD PharmD RN Other SPECIALTY: Hematology Infectious disease Internal medicine Medical oncology Nursing/Supportive care Other: CONGRESS REGISTRATION (A135-01) EMAIL ADDRESS TELEPHONE FAX INSTITUTE DEPARTMENT ADDRESS CITY STATE / PROVINCE ZIP / POSTAL CODE COUNTRY Check if you require special facilities or assistance and attach a note with specific details and requirements. REGISTRATION FEES 550 Discounted If payment received by 10 December 2009 625 Regular If payment received by 4 March 2010 695 Full/Onsite If payment received after 4 March 2010 200 Nurses/Residents/Students* *proof of eligibility must accompany registration Important Dates 12 th International 12-13 March 2010 Discounted Registration Deadline 10 December 2009 Abstract Submission Deadline 15 December 2009 Abstract Notifications Mailed 6 January 2010 Abstract Presenter Registration Deadline 28 January 2010 Regular Registration Deadline 4 March 2010 Presentation Dates 12 13 March 2010 PAYMENT METHOD American Express MasterCard Visa Check or Wire in the amount of: Card No. : Expiration Date: / Cardholder s Name: Signature: NOTE: After 4 March 2010 only credit card payments will be accepted for pre-registration. To pre-register, registration and payment must be received no later than 4 March 2010. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure that the program is being held as scheduled and to confirm that the meeting is not full. For registration fees to be refunded, written notice of cancellation must be received at meetings@imedex.com no later than 4 March 2010. The amount of registration fees remitted, minus a 90 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after 4 March 2010. Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this program should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda content is subject to change without notice. 3 WAYS TO LEARN PRINT materials are produced by Imedex for your reference needs ONLINE products are produced by Imedex in 6 user-friendly formats LIVE meetings are produced by Imedex in 15 countries Visit www.imedex.com to learn more 4325 Alexander Drive Alpharetta, Georgia 30022-3740, USA Imedex is committed to environmental excellence. This publication is printed on FSC-certified paper, which is acid-free, and contains 10% post-consumer recycled content.

12th International 12-13 March 2010 Chair Brussels, Belgium Local Chair Mario Dicato, MD Luxembourg Medical Center Session Chairs: J. Peter Donnelly, PhD University Medical Center St. Radboud Nijmegen, The Netherlands Miguel A. Sanz, MD, PhD University Hospital La Fe Valencia, Spain John R. Wingard, MD University of Florida Shands Cancer Center Gainesville, Florida, United States 2ND ANNOUNCEMENT AND C A L L F O R A B S T R AC TS W W W. I M E D E X. C O M

12 th International 12-13 March 2010 Who Should Attend/ Target Audience This educational activity is designed for medical oncologists, infectious disease specialists, hematologists, hospitalists, and other physicians, physicians-in-training, and healthcare professionals interested and/or involved in the care of patients with febrile neutropenia. Learning Objectives Upon completion of this activity, participants should be able to: Discuss and evaluate the clinical use of prophylactic versus empiric or preemptive therapy of fungal infections in febrile neutropenic patients Discuss the appropriate selection and practical utilization of replacement antibiotics for therapy of infections caused by resistant bacteria in febrile neutropenic patients Describe the role of native immunity on susceptibility and severity of infection in patients with febrile neutropenia Identify and assess management strategies for infections in patients undergoing stem cell transplant from alternative sources and donors Compare current and emerging therapies in the prevention and management of patients with febrile neutropenia Letter from the Chair Dear Colleagues, It is my pleasure to invite you to the 12th International Febrile Neutropenia. For this winter s meeting, we are delighted to be gathering in the capital city of the Grand Duchy of Luxembourg - a small country of great attractions at the very heart of Europe. We hope you will be able to join us for what is sure to be a rewarding and dynamic experience, as your perspectives and contributions add immeasurable value to this international symposium. This scientific meeting is designed to provide medical oncologists, infectious disease specialists, and other interested healthcare professionals with the most salient aspects of the etiology, diagnosis, and state-of-the-art management of febrile neutropenia. Topics are selected each year from recent developments in the field, current controversies and complicated cases. The highly interactive format includes 4 sessions; each comprised of a state of the art presentationlecture, followed by a cutting-edge research presentations relating to the topic, a case discussion focusing on the practical application of the topic, and a summary. There is always opportunity for extensive discussion of the presented data. We will again be accepting abstracts for both oral and poster presentations and encourage you to submit your work by the 15 December deadline. We look forward to reviewing and sharing your research findings with the community. Attendees have offered high praise for the quality of the scientific program and the international panel of experts in the faculty, and they have stated that participation in this conference significantly enhances their knowledge of the implications and management of febrile neutropenia. We hope you will plan to join us this year. Warmly, Comments from your colleagues: This is one of the best conferences I ve been to in terms of educational value and scientific rigor This conference is excellent and difficult to improve! Important consensus on management of febrile neutropenia The case presentations were interesting and excellent!! Very well organized with an excellent format. The interaction was excellent. The symposium was very impressive-best Regards and Thank You. Very, very good and useful Imedex is a brand and assumed name used by Imedex, LLC (hereby referred to as Imedex). Imedex is solely responsible for this agenda s content. Although Imedex attempts to ensure that the information in our program is accurate and timely, matters and opinions discussed and/or presented with respect to clinical matters are those of the discussion participants only, and not necessarily those of Imedex. Moreover, although Imedex attempts to identify and integrate the most qualified medical professionals in our program, TO THE FULLEST EXTENT PERMITTED BY LAW, IMEDEX EXPRESSLY DISCLAIM ALL WARRANTIES, EITHER EXPRESS OR IMPLIED, STATUTORY OR OTHERWISE, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OF MERCHANTABILITY, NON-INFRINGEMENT OF THIRD PARTIES RIGHTS, AND FITNESS FOR A PARTICULAR PURPOSE, WITH RESPECT TO THE CONTENT PRESENTED. IMEDEX FURTHER MAKES NO REPRESENTATIONS OR WARRANTIES ABOUT THE ACCURACY, RELIABILITY, COMPLETENESS OR TIMELINESS OF THE CONTENT OR ANY MATERIAL PRESENTED. In addition, the material presented and related discussions are not intended to be medical advice, and the presentation or discussion of such material is not intended to create and does not establish a physician-patient relationship. Medical advice of any nature should be sought from an individual s own physician. Neither Imedex nor any of its subsidiaries or affiliates is affiliated with or formally endorsed by a medical society. Copyright 2009 Imedex, LLC. All rights reserved. Reproduction in whole or part is prohibited without prior written consent from Imedex and contributing faculty.

Faculty 12 th International 12-13 March 2010 Elias Anaissie, MD University of Arkansas School of Medical Sciences Little Rock, Arkansas, United States Mickael Aoun, MD Brussels, Belgium Nicole Blijlevens, MD St. Raboud University Medical Center Nijmegen, The Netherlands Catherine Cordonnier, MD Hôpital Henri Mondor Créteil, France Mario Dicato, MD Luxembourg Medical Center J. Peter Donnelly, PhD St. Raboud University Medical Center Nijmegen, The Netherlands Aspasia Georgala, MD Brussels Belgium Brussels, Belgium Ofer Levy, MD, PhD Harvard Medical School Boston, Massachusetts, United States Louis B. Rice, MD Louis Stokes Cleveland VA Medical Center Cleveland, Ohio, United States Jaime Sanz, MD University Hospital La Fe Valencia, Spain Miguel A. Sanz, MD, PhD University Hospital La Fe Valencia, Spain Wilfried A. M. Schroyens MD, PhD University Hospital Antwerp Antwerp, Belgium Thomas J. Walsh, MD National Cancer Institute Bethesda, Maryland, United States John R. Wingard, MD University of Florida Gainesville, Florida, United States Call for Abstracts Participants interested in presenting data should submit abstracts online at www.imedex.com by 15 December 2009. Abstracts are subject to acceptance by the Scientific Committee Acceptance notifications and guidelines for poster presentation will be sent on 6 January 2010. Authors of accepted abstracts who have not registered will have until 28 January 2010 to do so at the rate of 550. After this date, abstracts without registered presenters will be disregarded. Abstract Guidelines Follow the online instructions Abstracts must be written in English Accepted format: Word document format, 9 point Arial font, 500 word count limit Use a concise title List affiliations of author(s) as briefly as possible, with city, state and country Place an asterisk (*) before the name of the presenting author Use standard and well-accepted abbreviations When using references, use standard and well-accepted formats Abstract content should be single-spaced, typed in lower case and contain: Purpose of the study Summarized description of the project Results and conclusions Submission Deadline 15 December 2009 Submission Instructions Go to www.imedex.com, select this Congress and follow instructions in the Abstracts section. Corporate Support Several options are available to companies interested in supporting this symposium. For more information, please contact Imedex at +1 (770) 751 7332 or by email at cme@imedex.com. Congress Organizer 4325 Alexander Drive Alpharetta, Georgia 30022-3740, USA Tel.: +1 (770) 751 7332 Fax: +1 (770) 751 7334 Email: meetings@imedex.com www.imedex.com

Scientific Agenda Friday, 12 March 2010 Saturday, 13 March 2010 8:00 8:00 Introduction Session I: Prophylactic versus empiric or preemptive therapy of fungal infections Chair: J. Peter Donnelly, PhD Co-Chair: Nicole Blijlevens, MD 8:10 State-of-the art lecture: Pre-emptive versus empirical anti-fungal therapy in neutropenic cancer patients Catherine Cordonnier, MD Welcome and introduction to day two Mario Dicato, MD Session III: The role of native immunity on susceptibility and severity of infection Chair: John R. Wingard, MD Co-Chair: Mario Dicato, MD 8:10 State-of-the art lecture: Why do some neutropenic patients get sick and others do not? The role of innate immunity polymorphisms Elias Anaissie, MD 8:55 9:10 8:55 9:30 9:10 10:20 Case presentation Thomas J. Walsh, MD 9:30 10:20 11:10 J. Peter Donnelly, PhD Case presentation Ofer Levy, MD, PhD 11:10 11:15 Lunch break John R. Wingard, MD 11:15 Lunch break Session II: Replacement antibiotics for therapy of infections caused by resistant bacteria Chair: Co-Chair: Wilfried A. M. Schroyens MD, PhD Session IV: Infections related to alternative transplant procedures 13:30 Chair: Miguel A. Sanz, MD, PhD Co-Chair: John R. Wingard, MD State-of-the art lecture: Treatment of antibioticresistant bacteria: A major challenge for the next decade Louis B. Rice, MD 13:30 State-of-the art lecture: Infections in patients undergoing stem cell transplant from alternative sources and donors 14:15 14:30 14:15 14:30 14:50 14:50 15:40 Case presentation: Mickael Aoun, MD and Aspasia Georgala, MD 15:40 Case presentation: Jaime Sanz, MD 16:30 Miguel A. Sanz, MD, PhD 16:40 Adjourn with summary by chair and local chair and Mario Dicato, MD 16:30 16:40 Adjourn Visit www.imedex.com for the most up-to-date agenda and to register.

Registration Fees Discounted 550 If payment received by 10 December 2009 Regular 625 If payment received by 4 March 2010 Full 695 If payment received after 4 March 2010 Nurses/Residents/Students* 200 *proof of eligibility must accompany registration Registration Procedures To Register: You may register online by 4 March 2010 at www.imedex.com, by calling Imedex at +1 (678) 242 0906 or by returning the registration form in this program by mail or fax. If you mail the form, please keep a copy for your records. Registration confirmations will be issued before the meeting. To qualify for special registration fees, registration and full payment must be received by Imedex by the dates specified. Payment: To pre-register, registration and payment must be received no later than 4 March 2010. Please register onsite after this date. Contact Imedex at +1 (678) 242 0906 or visit our website at www.imedex.com to ensure the course is being held as scheduled and to confirm that the meeting is not full. Registration fees must be remitted by credit card or check. Checks should be payable to Imedex. Attendee is not registered until full payment is received. Registration Fee Inclusions: Registration fees include admittance to all scientific sessions, congress materials, processing of certificates of attendance or continuing medical education, and all event functions as specified in the program. Cancellation: For registration fees to be refunded, written notice of cancellation must be received at meetings@imedex.com no later than 4 March 2010. The amount of registration fees remitted, minus a 90 administrative charge, will be refunded after the conference. Substitutions are accepted with written notification. No refunds will be made if notice is received after 4 March 2010. Imedex does not accept responsibility for covering travel, accommodation or any other costs incurred by registrants in the rare event that this program should be canceled for any reason. Every effort will be made to give reasonable notice in the event of cancellation. The event agenda is subject to change without notice. Italian Participants Alijet & Fargo International SRL has been appointed as the official agency for government authorization for Italian participants. You may contact them directly at: Alijet & Fargo International SRL Via Pietro Maroncelli 44/66, 50137 Firenze, Italy Tel.: +39 055 600 555 Fax: +39 055 609 078 4 EASY ways to register: ONLINE... www.imedex.com FAX US... +1 (678) 242 0920 Hotel Accommodations CALL US... The Registrar will take your registration over the phone. +1 (678) 242 0906 MAIL US... Imedex 4325 Alexander Dr. Alpharetta, GA 30022-3740, USA Le Royal Luxembourg 12, boulevard Royal L-2449 Tel.: +352 24 16 16 1 Fax: + 352 22 59 48 www.hotelroyal.lu Following the lines of the purest hotel traditions, the hotel «Le Royal» welcomes you to its 210 rooms and suites, all of which are spacious, elegant and entirely air-conditioned. Their layout has been arranged to respond to the needs and comfort of an international business and tourist clientele. For the convenience of attendees, a limited number of rooms have been reserved until 12 February 2010 at a discounted rate of 200.00 for single occupancy or 227.00 for double occupancy. These rates include buffet breakfast, city tax, service and V.A.T. This rate is not guaranteed outside the Congress dates or after 12 February 2010. To reserve your room please contact the Le Royal Luxembourg reservations department at +352 24 16 16 1 or visit the Imedex s website for hotel reservation links. To receive the group rate, callers must identify themselves as being with the 12th International Febrile Neutropenia group. Reservation requests received after 12 February 2010 may not be guaranteed the group rate.