CIMIT CoLab Accelerating the Healthcare Innovation Cycle

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CIMIT CoLab Accelerating the Healthcare Innovation Cycle John Collins, CIMIT JCollins11@partners.org Vinit Nijhawan, Boston University Vinit@bu.edu

CIMIT: Mission Accelerate the healthcare innovation cycle by: Facilitating collaboration between: Clinicians, technologist, entrepreneurs & Co s in: Creating novel products, services and procedures to: Improve Patient Care Page - 2

3 of >600 Project Examples Operating Room of the Future Optical Coherence Tomography Seizure Detection Procedures & Systems Start-ups Licensing CIMIT s >14 + years as a living lab for innovation Page - 3

CIMIT Consortium A Center at VA Boston 1998 2000 2002 2004 2006 2008 2010 2012 Affiliates Page - 4

Boston University is The 4th largest private university in the United States, with: 16,000+ undergraduates 12,000+ graduate students 4000+ Faculty Made up of 17 colleges and schools, including: Medicine Law Management Engineering Public Health Education Communications One of the largest international student populations with 28% of students university -wide from more than 100 countries Page - 5

A research institution at the scientific forefront 2008 Nobel Prize winner (shared) in Chemistry Osamu Shimomura, Ph.D. Over 1,000 sponsored research grants (NIH, DOD, DOE, etc) in 2006 with a particular of biomedical research and extensive new facilities MIT $640M Harvard $480M BU $370M One of 10 University centers in the US to receive Phase 1 funding from the Wallace H. Coulter Foundation Translational Research Partnership in Biomedical Engineering Partner with Fraunhofer Gesellschaft to create the BU-Fraunhofer Alliance for Medical Devices Additional programs: Ignition Awards, NIH CTSA, Photonics Center, CIMIT Page - 6

Healthcare Innovation Cycle Impact (Commercialize) Products/ Services Implement Best Practices Impact (Disseminate) Actual Standard of Care Innovation: A process by which an unmet need is resolved by stimulating and then translating ideas and/or inventions into sustainable products or services. Proof of Value Improve Proof of Principle Insight & Ideas Challenges & Needs Invent Import Inform Enabling Technologies Page - 7

Healthcare Innovation Cycle Unaware, Don t See Relevance Too Expensive Products/ Services Regulatory Wall Lost IP, No FTO Best Practices Resistance to Change In reality, many innovations often get stalled or derailed for reasons that could have been anticipated and avoided Proof of Value No Appreciation Actual Standard of Care Proof of Principle NIH, Never Knew Too Busy, Too Good, Too Special Challenges & Needs Not Shared Missing Skills Enabling Technologies Page - 8

Healthcare Innovation Cycle Products/ Services Best Practices Actual Standard of Care CIMIT focuses on the process, helping uncover needs, form teams, then anticipate and navigate the innovation cycle to maximize & speed impact Proof of Value Proof of Principle Challenges & Needs Enabling Technologies Page - 9

OTD Interface Map Alumni CMLD Etc. Photonics Center Coulter Program CTSI Fraunhofer Development Finance HR Public Relations Investment Office Research Compliance Trainees Research Programs Internships ITEC Undergraduate Students Education Inventions VP Research/ Provosts OSP Ignition Awards Faculty Univ. Admin. OGC OTD Business Outreach Launch Awards Service Providers Law Firms Thickness of Line Indicates Level of Activity AUTM Professional Societies Licenses Incubation Database subscriptions Networking BioSquare Consultants Technology Transfer Society LES VC Industry Entrepreneurs Mentors NCET2 Page - 10

Need: Collaborative Teams Companies have long focused on processes to support collaborative teams and now on Open Innovation Academic investigators have long practiced Open Innovation, institutions must support them in dynamic teaming and navigating the innovation cycle Page - 11

CoLab: Collaboration Infrastructure Know-How Innovation Models CIMIT Model Open Innovation Lead Users Jobs-to-be-Done Knowledge in Processes (i.e. IP) Working content Publications Powered by: Scalable Technologies Available Data Bases Social Media Web 2.0 Etc. Enabling Configurable Workflows Dynamic Networks Smart Search Page - 12

Vision: Collaborative Network Boston Hub (CIMIT) UK Hub Catalan Hub Singapore Hub Thematic Networks Other Geo/Org Hubs Page - 13

CoLab: Product Architecture 1) Solutions: A suite of tools to facilitate and manage at least part of the innovation cycle for an organization or group Includes pre-configured Modules Allows users to reconfigure or create own Modules SaaS offering, fees base on functionality 2) Enterprise: Linking and coordinating collaboration and innovation activities for an organization Process, reporting and sharing requirements established Flexibility for each group to go beyond base req s Discounts based on number of Solutions 3) Hub or Network: CoLab Solutions and /or Enterprises can all coordinate, share and collaborate w/no additional fees Hub/ Network Page - 14

CoLab: Pre-Configured Modules Solicitation Manager Needs & Ideas Capture Proposal Process Manager Impact Planner Campaign Manager Portfolio & Impact Tracker Portfolio Manager Regulatory Master Filer Impact Tracker Knowledge Curator Workgroups Connector Content Curator Funding Finder IP Facilitator Intellectual Property Curator IP Bus. Dev. Manager IP Licensing & Ops Manager Innovation Disseminator Best Practices Curator Procurement Facilitator = Part of Base Solution Enterprise Director Report Generator Sharing Rules Manager Page - 15

Going Forward: Lead User Roll-out CoLab can help foundations, care providers and universities join us in creating the collaboration platform we all need! Page - 16