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Grant Application Date Submitted: Proposal Type: If renewal, current grant: Resubmission? 1st or 2nd: TITLE OF PROJECT (Titles exceeding 81 characters, including spaces and punctuation, will be truncated.) Comm Code: APPLICANT NAME HIGHEST DEGREE(S) POSITION TITLE: ACADEMIC RANK: DIVISION: APPLICANT S CURRENT INSTITUTION MAILING ADDRESS (Street, city, state, postal code, country) DEPARTMENT: E-MAIL ADDRESS: Tel: Fax: PROGRAM ELIGIBILITY INFORMATION: (Responses to selected fields displayed below. For some grant programs this section may be blank.) Name Address DATES OF PROPOSED PROJECT (MM/DD/YYYY) From Through SIGNING OFFICIAL FOR Name Title Address Tel: Fax: Tel: Fax: EIN E-MAIL ADDRESS DUNS HUMAN SUBJECTS No Yes VERTEBRATE ANIMALS No Yes Human Subjects Assurance No. IRB Status: IRB Date: Animal welfare assurance no. IACUC Status: IACUC Date: ASSURANCE OF THOSE SIGNING THIS APPLICATION: I certify that the statements in this Application that pertain to me and my Institution are true, complete, and accurate to the best of my knowledge, and that I have provided all information required by this Application. I am aware that false, fictitious, or fraudulent statements or claims may result in criminal, civil, or administrative penalties. I agree that I will (and the Signing Official further represents that the institution will) comply with all Grant Policies of the Society, including reporting requirements, to the extent applicable. I understand that a failure to comply with such Policies, or the the terms of the Application, or any additional terms associated with a Grant, may result in the Society suspending or cancelling Grant funding, to be decided by the Society at its sole discretion. The Applicant certifies, and the Signing Official certifies that the Institution has verified, that the Applicant is legally eligible to work in the United States of America for the period of the award. SIGNATURE OF APPLICANT DATE SIGNATURE OF DEPARTMENT HEAD DATE. SIGNATURE OF SIGNGING OFFICIAL DATE

Applicant: Role Name Institution Title Division Dept Address Role Name Institution Title Division Dept Address Application Contacts Tel: Fax: Tel: Fax: E-mail E-mail Role Role Name Name Institution Institution Title Title Division Division Dept Dept Address Address Tel: Fax: Tel: Fax: E-mail E-mail Role Role Name Institution Title Division Dept Address Name Institution Title Division Dept Address Tel: Fax: Tel: Fax: E-mail E-mail Role Role Name Name Institution Institution Title Title Division Division Dept Address Dept Address Tel: Fax: Tel: Fax: E-mail E-mail

GENERAL AUDIENCE SUMMARY APPLICANT NAME DATE SUBMITTED TITLE OF PROJECT (Titles exceeding 81 characters, including spaces and punctuation, will be truncated.) This General Audience Summary will become public information; therefore, do not include proprietary/confidential information.

Principal Investigator: [Click here and type last name, first name] 1.1 TABLE OF CONTENTS Cover Pages (Signature Page, Contact Page, General Audience Summary) Table of Contents... 1.1 Reply to Previous Review (resubmitted and renewal applications)... 2.1 Previous Critiques (resubmitted and renewal applications) Description of the Program... 3.1 Career Development Activities for Beginning Investigators... 4.1 Composition of Local Institutional Research Grant Review Committee... 5.1 Biographical Information (Principal Investigator)... 6.1 Biographical Information (Committee Members)... 7.1 Documentation of Interaction with the Local American Cancer Society... 8.1 Procedure for Publicizing Availability of Funds... 9.1 How Allocations Are to be Made... 10.1 Justification for Funds Requested... 11.1 (New Applications Only) Documentation of Applicant Pool Size... 12.1 Examples of Research to be Supported and Biographical Information... 13.1 (Renewals Only) Summary Tables Table I -- Summary of Pilot Project Grants... 12.1 Table II -- Summary of Unfunded Applications... 13.1 Table III -- Summary of Publications Resulting from this Support... 14.1 Table IV -- Summary of Grants Resulting from this Support... 15.1 Table V -- Five Year Summary of Funding... 16.1 Table VI -- Summary of All Publications and Grants Obtained... 17.1 Current Pilot Project Grant Applications... 18.1 Pilot Project Progress Reports... 19.1 Appendix List:

Principal Investigator: [Click here and type last name, first name] 2.1 REPLY TO PREVIOUS REVIEW (NOT APPLICABLE TO NEW APPLICATIONS)

Principal Investigator: [Click here and type last name, first name] 3.1 DESCRIPTION OF THE PROGRAM (limit to 4 pages or less)

Principal Investigator: [Click here and type last name, first name] 4.1 CAREER DEVELOPMENT ACTIVITIES FOR BEGINNING INVESTIGATORS

Principal Investigator: [Click here and type last name, first name] 5.1 PRINCIPAL INVESTIGATOR AND INSTITUTIONAL RESEARCH GRANT REVIEW COMMITTEE Professor Associate Professor Assistant Professor Other Total Percentage Summary of Committee Composition Basic Research Clinical Research Cancer Control and Population Sciences Total

Principal Investigator: [Click here and type last name, first name] 5.2 MEMBERS OF LOCAL INSTITUTIONAL RESEARCH GRANT REVIEW COMMITTEE (Add lines as needed.) Name, Degree, Title Department, School Research Interest

Principal Investigator: [Click here and type last name, first name] [#].2 NAME BIOGRAPHICAL SKETCH Provide the following information for the Principal Investigator and each Committee Member. Follow this format for each person. DO NOT EXCEED THREE PAGES. POSITION TITLE EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) INSTITUTION AND LOCATION DEGREE (if applicable) YEAR(s) FIELD OF STUDY POSITIONS AND HONORS: PROFESSIONAL SOCIETY MEMBERSHIPS AND SERVICE

Principal Investigator: [Click here and type last name, first name] [#].2 GRANT FUNDING HISTORY: (Include current and previous funding related to cancer research.) PUBLICATIONS: (List in chronological order; if a partial list is given, indicate total number of publications)

Principal Investigator: [Click here and type last name, first name] 8.1 DOCUMENTATION OF INTERACTION WITH THE LOCAL AMERICAN CANCER SOCIETY A. IRG Awardees Interaction with the American Cancer Society B. All Other Interactions with the American Cancer Society

Principal Investigator: [Click here and type last name, first name] 9.1 PROCEDURE FOR PUBLICIZING AVAILABILITY OF FUNDS

Principal Investigator: [Click here and type last name, first name] 10.1 HOW ALLOCATIONS ARE TO BE MADE

Principal Investigator: [Click here and type last name, first name] 11.1 JUSTIFICATION FOR FUNDS REQUESTED CATEGORY Renewal applications only Current number of awards Current funding Requested number of awards Year 1 Year 2 Year 3 TOTALS Requested funding ($30,000 maximum per pilot project grant) Pilot projects Special interest pilot projects (limit 1 per year) TOTALS

Principal Investigator: [Click here and type last name, first name] 12.1 DOCUMENTATION OF APPLICANT POOL SIZE (NEW APPLICATIONS ONLY) Name, Degree, Academic Title Department, School Date Appointed Research Interest * Typically the number of proposed pilot projects to be awarded per year does not exceed 30% of the number of potential applicants listed on this table.

Principal Investigator: [Click here and type last name, first name] 13.1 BIOGRAPHICAL INFORMATION First Name, Last name, Degree(s) EXAMPLES OF RESEARCH TO BE SUPPORTED (NEW APPLICATIONS ONLY) Academic Title Department School Citizenship Status U.S. Non-U.S. citizen (temporary resident) *** Non-U.S. citizen (permanent resident) Non-U.S. citizen *** Year last degree conferred: Year of first independent position: Verification of Applicant Eligibility by Department Chair (applicants must be within six years of their first independent research or faculty appointment, must be salaried faculty with appropriate committed research facilities, and may not have competitive national funding active at the start date of the proposed IRG allocation) Name of Department Chair Signature Date: Education Degree/year conferred Institution/Location Field of study Training Title Mentor Institution/Location Dates *** any applicant for IRG pilot project funding who is not a U.S. citizen must hold a visa that will allow him or her to remain in the U.S. long enough to complete the IRG pilot project. It is the responsibility of the institution to determine and document the visa status of any non-citizen recipient of IRG funds. Continued on next page

Principal Investigator: [Click here and type last name, first name] 13.2 First Name, Last name, Degree(s) Appointments Title Institution/Location Dates Other Research Support: Publications (use continuation page if necessary) Continued on next page

Principal Investigator: [Click here and type last name, first name] 13.3 First Name, Last name, Degree(s) PROJECT TITLE: DESCRIPTION OF RESEARCH PROPOSED (including Background, Objective/Hypothesis, Specific Aim(s), Study Design, and Cancer Relevance.):

Principal Investigator: [Click here and type last name, first name] 12.1 TABLE I SEVEN YEAR SUMMARY OF PILOT PROJECT GRANTS 1 (Use continuation pages as needed.) Term of Award 2 (MM/YY MM/YY) Investigator Name, Degree Academic Title 3 Department, School Project Title 4 Priority Score Amount of Award 5 1 For seven years, starting with the most recent year (January December) and working backwards. This will be for fewer years if a first renewal 2 These dates should match those on Table V. 3 At time of award and currently, if known. 4 Use an asterisk (*) to indicate if a Special Interest Award. 5 If relevant, amount should also reflect any matching funds.

Principal Investigator: [Click here and type last name, first name] 13.1 TABLE II SEVEN YEAR SUMMARY OF UNFUNDED APPLICATIONS * (Use continuation pages as needed.) Review Dates (MM/YY) Investigator Name, Degree Academic Title Department, School Project Title Priority Score *For seven years starting with the most recent year (January-December). This will be for fewer years if a first renewal.

Principal Investigator: [Click here and type last name, first name] 14.1 Term of Award (MM/YY MM/YY) TABLE III SUMMARY OF PUBLICATIONS RESULTING FROM THIS SUPPORT Investigator Name, Degree Project Title Publications* * List only publications that include the required acknowledgement of ACS IRG funding support.

Principal Investigator: [Click here and type last name, first name] 15.1 Term of Award (MM/YY MM/YY) TABLE IV SUMMARY OF GRANTS RESULTING FROM THIS SUPPORT Investigator Name, Degree and Role on Grant Project Title Grant # (including agency) and Amount

Principal Investigator: [Click here and type last name, first name] 16.1 Year (MM/YY) TABLE V SEVEN-YEAR SUMMARY OF FUNDING* Number of Eligible Applications Reviewed (Table I and II data) Number of Applications Funded (Table I data) % Applications Funded Totals *Information here must be consistent with numbers on Tables I and II.

Principal Investigator: [Click here and type last name, first name] 17.1 TABLE VI SUMMARY OF ALL PUBLICATIONS AND GRANTS OBTAINED 1 Term of Award (MM/YY MM/YY) Investigator Name, Degree Resulting From ACS-IRG SUPPORT Grants Awarded Grants Pending Publications Resulting From OTHER FUNDING SOURCES Grants Awarded Grants Pending Publications SUBTOTAL Totals 2 : 1 Enumerate only national peer reviewed grants and published or in press peer reviewed publications that acknowledge ACS funding. 2 Provide subtotals for each year and an overall total in the space indicated.

Principal Investigator: [Click here and type last name, first name] 18.1 APPLICATION FOR A PILOT PROJECT GRANT FROM AMERICAN CANCER SOCIETY INSTITUTIONAL RESEARCH GRANT #IRG BIOGRAPHICAL INFORMATION First Name, Last name, Degree(s) Academic Title Department School Citizenship Status U.S. citizen Non-U.S. citizen (temporary resident) *** Non-U.S. citizen (permanent resident) Non-U.S. citizen *** Year last degree conferred: Year of first independent position: Verification of Applicant Eligibility by Department Chair (Applicants must be within six years of their first independent research or faculty appointment, must be salaried faculty with appropriate committed research facilities, and may not have competitive national funding active at the start date of the proposed IRG allocation.) Name of Department Chair Signature Date: Education Degree/year conferred Institution/Location Field of study Training Title Mentor Institution/Location Dates *** any applicant for IRG pilot project funding who is not a U.S. citizen must hold a visa that will allow him or her to remain in the U.S. long enough to complete the IRG pilot project. It is the responsibility of the institution to determine and document the visa status of any non-citizen recipient of IRG funds. Continued on next page

Principal Investigator: [Click here and type last name, first name] 18.2 First Name, Last name, Degree(s) Appointments Title Institution/Location Dates Other Research Support: Publications (use continuation page if necessary) Continued on next page

Principal Investigator: [Click here and type last name, first name] 18.3 First Name, Last name, Degree(s) PROJECT TITLE: ABSTRACT: Provide a brief (300-500 words) summary of the research, including Background, Objective/Hypothesis, Specific Aim(s), Study Design, and Cancer Relevance. The final sentence of the abstract should summarize the focus and cancer relevance of the project in non-scientific terms.

Principal Investigator: [Click here and type last name, first name] 18.4 First Name, Last name, Degree(s) PROJECT TITLE: DESCRIPTION OF RESEARCH PROPOSED (use up to four continuation pages as necessary):

Principal Investigator: [Click here and type last name, first name] 18.5 First Name, Last name, Degree(s) TOTAL AMOUNT REQUESTED: TERM: from to BUDGET PROPOSED: A. Personnel B. Permanent Equipment C. Supplies D. Miscellaneous BUDGET JUSTIFICATION:

Principal Investigator: [Click here and type last name, first name] 19.1 INSTITUTIONAL RESEARCH GRANT #IRG PILOT PROJECT PROGRESS REPORT (Revision date: ) Amount Term: from to Investigator (Name with degree(s), Title, Department, School) Project Title Results: Summarize the work accomplished under the grant and the results achieved. Please include the relevance of the work to cancer. Limit this portion of the report to one page.

Principal Investigator: [Click here and type last name, first name] 19.2 Investigator: PILOT PROJECT PROGRESS REPORT (2 of 3 pages) Peer reviewed publications resulting from this support (published or in press only). Attach a copy of the publication cover page(s) including the abstract and acknowledgement of ACS funding for each relevant publication. Abstracts, book chapters, and other publications (published or in press only) during or after this support National competitive grants obtained or pending as a result of this support, or currently pending Other grants obtained during or after this support Patents granted or applied for: Interactions with the local American Cancer Society: