TITLE Skeletal Muscle Satellite Cells and Regeneration Steamboat Springs, CO Organizers: Robert Krauss Icahn School of Medicine at Mount Sinai New York, NY Andrew Brack University of California San Francisco San Francisco, CA Tom Cheung Hong Kong University of Science and Technology Hong Kong Sunday, July 8, 2018 Time 4:00 p.m. 9:00 p.m. 6:00 p.m. 7:00 p.m. Welcome Reception 7:00 p.m. 8:00 p.m. DINNER 8:00 p.m. 9:00 p.m. Keynote Speaker The role of muscle cells in orchestrating planarian regeneration 9:00 p.m. 9:20 p.m. An anniversary: twenty years of muscle satellite cell meetings Peter Reddien, MIT/HHMI Judy Anderson/Ron Allen Monday, July 9, 2018 Time 9:00 a.m. 9:15 a.m. Welcome from FASEB 9:15 a.m. 12:00 p.m. Session 1: Transcriptional and Epigenetic Regulation of Satellite Cells Chair: Andrew Brack
9:15 a.m. 9:45 a.m. 9:45 a.m. 10:15 a.m. 10:15 a.m. 10:30 a.m. 10:30 a.m. 11:00 a.m. 11:30 a.m. 12:00 p.m. Genetic and epigenetic regulation of satellite cells during aging Manipulation of epigenetic pathways in muscle stem cells to improve skeletal muscle disorders FASEB Sponsored Coffee Break Differential mrna processing during Satellite Cell Activation Shahrigim Tajbakhsh, Pasteur Institute Thomas Braun, Max Planck Institute Tom Cheung, HKUST 1:15 p.m. 3:00 p.m. Free Time and/or 1:30 p.m 2:30 p.m. Meet the Experts 3:00 p.m. 6:00 p.m. Session 2: Satellite Cell-Niche Interactions 3:00 p.m. 3:30 p.m. Niche Regulation of Satellite Cell Quiescence by Adhesion Molecules Chair: D Cornelison Robert Krauss, Mount Sinai 3:30 p.m. 4:00 p.m. 4:00 p.m. 4:15 p.m. 4:15 p.m. 4:45 p.m. 4:45 p.m. 5:15 p.m. 5:15 p.m. 5:45 p.m. 5:45 p.m. 6:00 p.m. Niche mechanics and satellite cell spatiotemporal control Coffee Break Syndecan-3 in myogenesis: a tale of many functions Extrinsic regulation of muscle stem cell specification Penney Gilbert, University of Toronto Dada Pisconti, University of Liverpool Florian Bentzinger, University of Sherbrooke 6:00 p.m. 7:00 p.m. 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 9:00 p.m. Poster Session 1 Tuesday, July 10, 2018 Time
9:00 a.m. 12:00 p.m. Session 3: Satellite Cells in Disease and Aging Chair: Tom Cheung 9:00 a.m. 9:30 a.m. 9:30 a.m. 10:00 a.m. 10:00 a.m. 10:15 a.m. 10:15 a.m. 11:00 a.m. 11:30 a.m. 12:00 a.m. Unravelling the causes of oxidative stress sensitivity in satellite cells in facioscapulohumeral muscular dystrophy Approaches to delay the progression of Muscular Dystrophy FASEB Sponsored Coffee Break and *Group Photo Understanding muscle stem cell regenerative decline with aging Pluripotent Stem Cell-Derived Myogenic Progenitors: Potential for Gene Correction andtherapeutic Application in Muscular Dystrophies Peter Zammit, University of London Graziella Messina, University of Milan Pura Munoz-Canoves, Pompeu Fabra University Rita Perlingeiro, University of Minnesota 1:15 p.m. 3:00 p.m. Free Time and/or 1:30 p.m 2:30 p.m. Career Development Workshop 3:00 p.m. 6:00 p.m. Session 4: Satellite Cell Polarity and Heterogeneity 3:00 p.m. 3:30 p.m. Molecular regulation of muscle stem cell function Chair: Dada Pisconti Michael Rudnicki, Ottawa Hospital Research Institute 3:30 p.m. 4:00 p.m. 4:00 p.m. 4:15 p.m. 4:15 p.m. 4:45 p.m. 4:45 p.m. 5:15 p.m. 5:15 p.m. 5:45 p.m. 5:45 p.m. 6:00 p.m. Muscle regeneration: no pain, no gain! Coffee Break Functional heterogeneity of muscle satellite cells Helen Blau, Stanford University Yusuke Ono, Nagasaki University Brad Olwin, University of Colorado 6:00 p.m. 7:00 p.m. 6:00 p.m. 7:00 p.m. DINNER
7:00 p.m. 9:00 p.m. Poster Session 2 Wednesday, July 11, 2018 Time a.m. Time p.m. 9:00 a.m. 12:00 p.m. Session 5: Satellite Cell Quiescence and Activation Chair: Robert Krauss 9:00 a.m. 9:30 a.m. Selective translation of mrna regulating the self-renewal of skeletal muscle stem cells Colin Crist, McGill University 9:30 a.m. 10:00 a.m. 10:00 a.m. 10:15 a.m. 10:30 a.m. 11:00 a.m. 11:30 a.m. 12:00 p.m. Quiescence and stem cell function FASEB Sponsored Coffee Break Regulation of satellite cell quiescence and activation Regulation of skeletal muscle satellite cell early activation Jyotsna Dhawan, Institute for Stem Cell Biology and Regenerative Medicine Tom Rando, Stanford University Fred Relaix, Paris Est-Creteil University 12:00 p.m. 12:30 p.m. Business Meeting 1:15 p.m. 4:00 p.m. Free time and/or Group Activity Session 6: Satellite Cell Regulation During Regeneration Chair: Pura Munoz-Canoves 4:00 p.m. 4:30 p.m. 4:30 p.m. 5:00 p.m. 5:00 p.m. 5:30 p.m. 5:30 p.m. 5:45 p.m. Regulation of muscle stem cell function during tissue repair Restorative macrophages secrete factors that boost myogenic fusion during skeletal muscle regeneration Alessandra Sacco, Sanford Burnham Prebys Institute Benedicte Chazaud, Universite Claude Bernard
5:45 p.m. 6:00 p.m. 6:00 p.m. 6:30 p.m. Business Meeting 6:30 p.m. 7:30 p.m. DINNER 7:30 p.m. 9:30 p.m. Poster Session 3 Thursday, Month, Day, Year Time a.m. Time p.m. 9:00 a.m. 12:00 p.m. Session 7: Satellite Cell Metabolism and Adaptation Chair: Benedicte Chazaud 9:00 a.m. 9:30 a.m. 9:30 a.m. 10:00 a.m. 10:00 a.m. 10:15 a.m. 10:30 a.m. 11:00 a.m. 11:30 a.m. 12:00 p.m. The role of damaged myofibers and muscle connective tissue fibroblasts in mediating muscle regeneration Novel roles for satellite cells in muscle adaptation FASEB Sponsored Coffee Break Satellite cell heterogeneity and metabolic bias Metabolic control of satellite cell function Gabrielle Kardon, University of Utah Charlotte Peterson, University of Kentucky Andrew Brack, UC San Francisco Vittorio Sartorelli, NIH 1:15 p.m. 3:00 p.m. Free Time 3:00 p.m. 6:00 p.m. Session 8: Emerging Themes Chair: Brad Olwin 3:00 p.m. 3:30 p.m. 3:30 p.m. 4:00 p.m. In vivo cell dynamics of muscle stem cell behaviours during muscle regeneration in zebrafish A pillar of the community (effect): EphA7 promotes collective myoblast differentiation Peter Currie, Monash University D Cornelison, University of Missouri 4:00 p.m. 4:15 p.m. 4:15 p.m. 4:45 p.m. Coffee Break
4:45 p.m. 5:15 p.m. 5:15 p.m. 5:45 p.m. 5:45 p.m. 6:00 p.m. NF-kB regulation of neonatal muscle growth Denis Guttridge, Ohio State University David Glass, Novartis Institute for Biomedical Research 7:30 p.m. 10:30 p.m. Banquet and Awards Friday, July 13, 2018 Time a.m. Time p.m. 9:00 a.m. Boxed Snacks to Go and DEPARTURES END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 www.faseb.org/src