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Continuing Medical Education Presents: 2013 NEPHROLOGY UPDATE: Journey through the Stages of CKD for the Primary Care Team In Cooperation with the National Kidney Foundation Friday, March 22, 2013 Ambassador Center 7794 Peach Street Erie, PA Course Director

GOAL The patient with acute kidney injury (AKI) remains at a high risk for increased in-hospital and outpatient morbidity and mortality. Emerging data show that a patient who had AKI remains at risk for CKD and patients with CKD have a higher mortality than the general population. The goal of this intense, full-day conference is to provide updated information on all the stages of chronic kidney disease and the primary care team s role in managing the care of these patients. Join your colleagues and gain the latest updates and practice guidelines in kidney care! Didactic presentations will be combined with panel sessions to best meet individual learning gaps. Electronic handouts will be made available to conference attendees. TARGET AUDIENCE Family practice physicians, hospitalists, intensivists, nurses, and other allied health care professionals involved in the care of patients with chronic kidney disease will benefit from participation in this activity. ACCREDITATION The is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. DESIGNATION The University of Pittsburgh designates this live activity for a maximum of 7.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded 0.7 continuing education units (CEUs), which are equal to 7.5 contact hours. NURSING ACCREDITATION is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center s Commission on Accreditation. NURSING CREDIT HOURS A maximum of 7.5 nursing contact hours will be awarded. Participants will be able to claim credit commensurate with the extent of their participation in the program. Accreditation refers to recognition of continuing nursing education activities only and does not imply or Commission on Accreditation approval or endorsement of any commercial product. DISCLOSURE Faculty for this activity have been required to disclose all relationships with any proprietary entity producing health care goods or services, with the exemption of non-profit or government organizations and non-health-care-related companies. CANCELLATION POLICY Tuition for cancellations postmarked or date stamped before March 8, 2013 will be completely refunded. After March 8, 2013 a $24 administration fee will be assessed. No refunds will be made after March 21, 2013. However, substitutes are welcome. Please notify s CME Department of substitutions and cancellations, via email to ham_cme@upmc.edu or by telephone at 814-877-4011, or via USPS mail to: CME Department, 201 State St., Erie, PA 16550. COMMERCIAL SUPPORT A complete list of supporters will be available as part of the program syllabus. SPECIAL NEEDS Participation by all individuals is encouraged. Advance notification of any special needs will help us provide better service. Please notify us of your needs at least two weeks in advance of the program by calling s CME office at 800-352-2553 or 814-877-4011.

NEPHROLOGY UPDATE SCHEDULE 7:30 to 8 a.m. Registration/Continental Breakfast 8 to 8:15 a.m. Introduction 8:15 to 9 a.m. Acute Kidney Injury Prevention: What is Your Role? Paul Palevsky, MD 9 to 9:45 a.m. Stage I CKD: Why Should You Care About Any Stage CKD? Chester Fox, MD 9:45 to 10:15 a.m. Stage II CKD: Your Time to Shine The Erie VA Experience 10:15 to 10:30 a.m. Refreshment Break 10:30 to 11:15 a.m. Stage III CKD: Kidney Versus Patient Death Someone Needs to Deal with It Martin Schreiber, Jr., MD 11:15 to 11:45 a.m. Morning Panel 11:45 a.m. to 12:30 p.m. Lunch and Networking 12:30 to 1:15 p.m. Stage IV CKD: Coordinating Primary Care with Kidney Care Beth Marie Piraino, MD 1:15 to 2 p.m. Stage V CKD: Primary Care s Role in Co-Management of a Dialysis Patient Kevin Ho, MD 2 to 2:15 p.m. Refreshment Break 2:15 to 3 p.m. Stage VI CKD: Answers to Your Questions About Kidney Transplantation Ron Shapiro, MD 3 to 3:45 p.m. Role of Primary Care in the Treatment of the Post-Transplant Patient Sundaram Hariharan, MD 3:45 to 4:30 p.m. Cardiorenal Syndrome(s): Perspectives from the Heart David Strasser, MD 4:30 to 5 p.m. Afternoon Panel with Reception 5 p.m. Adjournment

COURSE DIRECTORS Bayview Nephrology, Inc. Division of Nephrology Physician Quality Coordinator Vice President, Medical Staff PLANNING COMMITTEE Christopher Conn, CRNP Shannon Flynn UPMC Transplantation Services Donna Irish, RN Janet Parks, RN Cherie Peters National Kidney Foundation Margaret Pett Maggie Pratt National Kidney Foundation ATTIRE Attire for the conference is business casual. Since meeting room temperatures and personal comfort levels vary, it is recommended that you bring a sweater or jacket to the conference. LOCATION The conference is being held at the Ambassador Center behind the Courtyard by Marriott at 7794 Peach St., Erie, Pa. Peach St. Exit 24 AMBASSADOR CENTER FACULTY Chester Fox, MD Professor of Family Medicine Department of Family Medicine University at Buffalo The State University of New York Bayview Nephrology, Inc. Division of Nephrology Sundaram Hariharan, MD Medical Director of Kidney and Pancreas Transplantation UPMC Montefiore Professor of Medicine and Surgery Kevin Ho, MD Associate Professor of Medicine Renal-Electrolyte Division UPMC Paul Palevsky, MD Professor of Medicine Renal-Electrolyte Division Chief, Renal Section VA Pittsburgh Healthcare System Beth Marie Piraino, MD Professor of Medicine President, National Kidney Foundation Associate Dean, Admissions and Financial Aid Renal-Electrolyte Division UPMC Martin Schreiber, Jr., MD Chairman, Department of Nephrology and Hypertension Glickman Urological and Kidney Institute Cleveland Clinic Foundation Ron Shapiro, MD Professor of Surgery Robert J. Corry Chair in Transplantation Surgery Thomas E. Starzl Transplantation Institute David Strasser, MD Medicor Associates Division of Cardiology

OBJECTIVES At the conclusion of this activity, the participant should be able to: Outline the long-term clinical consequences of a patient who experiences AKI. Recognize the risk factors for development of AKI in the community and in the hospital settings. Describe the fundamental pathology of AKI. List tests available and in development to diagnose AKI. Outline what steps the PCP can take to avoid AKI in his/her patient. Outline the clinical burden of CKD as comorbidity and what it means clinically to the patient diagnosed with CKD. Review risk factors for the development of CKD. List measures of kidney function: serum creatinine, egfr, and proteinuria; discuss limitations on the use of egfr as a screening test for CKD in the general population. Discuss the National Kidney Foundation definition of CKD, its stages and clinical action step for each stage. Summarize the PCP s role in care of the patient with stage I CKD. Describe the relationship between serum creatinine, creatinine clearance, and glomerular filtration rate. Discuss why a valid 24-hour urine collection where GFR is calculated out is better than checking 24-hour urine for only creatinine clearance. Discuss why it is important to catch a patient in stage II CKD rather than stage V CKD. Outline how the Erie VA experience can be applied to any patient population. Discuss the limitation of stage III CKD nomenclature and the clinical need to distinguish the patient with stage CKD IIIA versus CKD IIIB. Identify, diagnose, and describe the medical management of complications of stage III CKD. Review the interventions to prevent the progression from stage III CKD. Describe why reversibility of kidney function is unlikely by the time a patient reaches stage IV CKD. Describe the signs, symptoms, and laboratory parameters of advancing CKD and outline indications for initiating renal replacement therapy. Discuss the importance of timely discussion about renal replacement therapy with a patient with stage IV CKD. Describe options of dialysis modalities. Review the fundamentals of various types of hemodialysis and peritoneal dialysis. Outline strategies that can be implemented by both the primary care team and the nephrologist in caring for a patient receiving dialysis. Outline steps to refer a patient for pre-emptive renal transplant in the state of Pennsylvania. Describe the renal transplantation process from patient candidacy, work-up, and evaluation for acceptability. Outline the basics of renal transplant surgery and post-op care. Review the steps for a person showing interest in being an organ donor. Discuss the role of the primary team in the management of a kidney transplant recipient. Outline how the primary team and the nephrology team can coordinate the medical care of a patient with a transplanted kidney. Define cardiorenal syndrome. Outline the clinical manifestations of a patient with cardiorenal syndrome. Describe current management strategies of cardiorenal syndrome and their limitations. JOIN OUR EMAIL LIST: To receive links to electronic brochures in the future and join our email list, please be sure to provide your email address on the registration form. Your email address will not be sold or used for any purpose other than to inform you about CME opportunities at.

2013 NEPHROLOGY UPDATE REGISTRATION The registration fee includes the seminar, electronic educational materials, continental breakfast, refreshment breaks, and lunch. If you have any questions, please contact the CME Office at 800-352-2553 or 814-877-3948. FEES: Physicians...$130 Nurses/Allied Health Professionals/Other... $60 Resident Physicians/Students...$25 ONLINE REGISTRATION: Registering online is the quickest and easiest way to reserve your space at conferences. Visit our online registration site at https://ccehs.upmc.com. Click the link for Upcoming Events and scroll down to the 2013 Nephrology Update: Journey through the Stages of CKD for the Primary Care Team section on the web page. Click the registration button and enter all the requested information. After registering, an electronic confirmation will be sent to you. Online registration is complete upon receipt of a confirmation email. If you do not receive this letter within 5 7 days of registration, please contact the CME Department at 814-877-4011. To assure participation, registration and payment are expected by March 8, 2013.

2013 NEPHROLOGY UPDATE Friday, March 22, 2013 Ambassador Center Erie, PA Other registration Methods Please fill out the form below: Name Circle Title: MD DO NP RN PA Other: Specialty Institution/Organization Street Address City, State, ZIP Daytime Phone Number Email Address My payment by check is enclosed. Return this form with payment to:, CME Department, 201 State Street, Erie, PA 16550 Checks should be made payable to. My payment by check will be mailed separately. Fax this completed form to CME Department: 814-877-4010. Mail payment with a copy of the completed registration form. I authorize the following credit card payment: $130 $60 $25 Visa MasterCard American Express Discover Card Number: Expiration Date (Month/Year): Signature: UPMC Journal Entry Transfer If you are a UPMC employee and your department will be responsible for payment, we can charge your department directly. DO NOT SUBMIT a disbursement to UPMC Accounts Payable. Complete the following: Business Unit: Account Number: Department ID Number: Name of Department Manager/Director: Authorized Department Signature: