Yeast Chromosome Biology & Cell Cycle July 15-July 20, 2018 Steamboat Grand, Steamboat Springs, Colorado

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Yeast Chromosome Biology & Cell Cycle July 15-July 20, 2018 Steamboat Grand, Steamboat Springs, Colorado Organizers: Jennifer Gerton, Investigator Stowers Institute for Medical Research Kansas City, Missouri M. K. Raghuraman (Raghu), Research Professor University of Washington Seattle, Washington Sunday, July 15, 2018 4:00 p.m. 9:00 p.m. Conference Registration 6:00 p.m. 7:00 p.m. Welcome Reception, open bar 7:00 p.m. 8:30 p.m. DINNER 8:45 p.m. 10:00 p.m. Keynote Address David Morgan, University of California San Francisco Regulatory enzymes that govern chromosome segregation in mitosis Monday, July 16, 2018 7:30 a.m. 12:00 p.m. Conference Registration 9:00 a.m. 12:15 p.m. GENERAL SESSION 1: Chromosome Structure Chair: Frank Uhlmann, The Francis Crick Institute 9:15 a.m. 9:45 a.m. Xiaolan Zhao, Memorial Sloan Kettering Cancer Center SUMO and Smc5/6 regulation of genome duplication 9:45 a.m. 10:15 a.m. Christian Haering, European Molecular Biology Laboratory Chromosome organisation by condensin complexes

10:15 a.m. 10:30 a.m. Short Talk Selected From Submitted Abstracts 10:30 a.m. 11:00 a.m. MORNING COFFEE BREAK & GROUP PHOTO 11:00 a.m. 11:30 a.m. Kerry Bloom, University of North Carolina at Chapel Hill Role of DNA loops in centromere organization 11:30 a.m. 12:00 p.m. Doug Koshland, University of California Berkeley 12:00 a.m. 12:15 p.m. Short Talk Selected From Submitted Abstracts 12:15 p.m. 1:15 p.m. LUNCH 1:15 p.m. 4:00 p.m. Free 4:00 p.m. 7:15 p.m. GENERAL SESSION 2: DNA Replication Session Chair: Steve Bell, MIT, HHMI 4:00 p.m. 4:30 p.m. Bonny Brewer, University of Washington 4:30 p.m. 5:00 p.m. Karim Labib, University of Dundee The end of chromosome replication 5:00 p.m. 5:30 p.m. John Diffley, The Francis Crick Institute How the replication helicase is loaded and activated 5:30 p.m. 5:45 p.m. Break 5:45 p.m. 6:15 p.m. Dirk Remus, Memorial Sloan Kettering Cancer Center Reconstituting budding yeast chromosome replication with purified proteins 6:15 p.m. 6:45 p.m. Nick Rhind, University of Massachusetts Medical School Regulation of Replication Timing 6:45 p.m. 7:15 p.m. Tony Carr, University of Sussex Mechanisms of recombination-dependent DNA replication 7:15 p.m. 8:15 p.m. Dinner 8:15 p.m. 10:15 p.m. Poster Session 1: Odd Numbers Tuesday, July 17, 2018 9:00 a.m. 12:15 p.m. GENERAL SESSION 3: Meiosis and Recombination Session Chair: Michael Lichten, NIH 9:00 a.m. 9:30 a.m. Sarah Zanders, Stowers Institute for Medical Research Meiotic Drive via a Gamete-Killing Poison and Antidote Encoded by a wtf Gene 9:30 a.m. 10:00 a.m. Rodney Rothstein, Columbia University Yeast chromosome mobility and genetic recombination 10:00 a.m. 10:15 a.m. Short Talk Selected From Submitted Abstracts 10:45 a.m. 11:15 a.m. Jim Haber, Brandeis University Checkpoint responses and repair of a broken chromosome 11:15 a.m. 11:45 a.m. Ted Weinert, University of Arizona Cancer Center

11:45 a.m. 12:15 a.m. Soni Lacefield, Indiana University Spindle checkpoint regulation of meiosis 12:15 p.m. 2:15 p.m. LUNCH and Meet the experts 2:15 p.m. 4:00 p.m. FREE TIME/ Meet the Experts 4:00 p.m. 6:45 p.m. GENERAL SESSION 4: Telomeres Session Chair: M. K. Raghuraman, University of Washington 4:00 p.m. 4:30 p.m. Julie Cooper, National Institutes of Health The How and Why of functional overlap between telomeres and centromere 4:30 p.m. 5:00 p.m. Songtao Jia, Columbia University Functional analyses of oncogenic histone mutations 5:00 p.m. 5:30 p.m. Kathy Friedman, Vanderbilt University Mechanisms of DNA double-strand break repair and tolerance 5:30-5:45 BREAK 5:45 p.m. 6:15 p.m. Raymund Wellinger, Université de Sherbrooke An RNA-centric view of telomerase action at telomeres 6:15 p.m. 6:45 p.m. Ginger Zakian, Princeton University Using Mass Spectrometry to identify new regulators of budding yeast telomerase 6:45 p.m. 7:45 p.m. DINNER 7:45 p.m. 10:00 p.m. POSTER SESSION 2 Even Numbers Wednesday, July 18, 2018 9:00 a.m. 12:00 p.m. GENERAL SESSION 5: Kinetochores and Spindles Session Chair: Jennifer Gerton, Stowers Institute for Medical Research 9:00 a.m. 9:30 a.m. Tomo Tanaka, University of Dundee Kinetochore-microtubule interaction in budding yeast 9:30 a.m. 9:45 a.m. Short Talk Selected From Submitted Abstracts 9:45 a.m.- 10:00 a.m. Short Talk Selected From Submitted Abstracts 10:00 a.m. 10:15 a.m. Short Talk Selected From Submitted Abstracts 10:45 a.m. 11:00 a.m. Short Talk Selected From Submitted Abstracts 11:00 a.m. 11:30 a.m. Stefan Westermann, University of Duisburg-Essen Biochemical and genetic analysis of the Budding Yeast Kinetochore 11:30 a.m. 12:00 p.m. Sue Jaspersen, Stowers Institute for Medical Research Yeast centrosome structure and function 12:00 p.m. 1:00 p.m. LUNCH 1:00 p.m. 6:00 p.m. FREE TIME Optional Group Activity 6:00 p.m. 7:00 p.m. DINNER 7:00 p.m. 10:00 p.m. GENERAL SESSION 6: Mitosis Chair: Kathy Gould, Vanderbilt University 7:00 p.m. 7:30 p.m. Liam Holt, NYU Langone Medical Center A polyglutamine domain in SWI/SNF enables transcriptional reprogramming in response to a transient ph change 7:30 p.m. 8:00 p.m. Jan Skotheim, Stanford University The biosynthetic basis of cell size control

8:00 p.m. 8:30 p.m. Doug Kellogg, University of California - Santa Cruz Control of cell growth and size 8:30 p.m. 8:45 p.m. BREAK 8:45 p.m. 9:00 p.m. Short Talk Selected From Submitted Abstracts 9:00 p.m. 9:30 p.m. David Pellman, Harvard Medical School, HHMI A mechanism controlling microtubule length and spindle size 9:30 p.m. 10:00 p.m. Eduardo Torres, University of Massachusetts Medical School Serine-dependent synthesis of lipids regulate the proliferation of aneuploid cells Thursday, July 19, 2018 9:00 a.m. 11:30 p.m. GENERAL SESSION 7: Chromatin and Nuclear Organization Chair: Anne Donaldson, Aberdeen University 9:00 a.m. 9:30 a.m. Toshi Tsukiyama, NIH Molecular mechanisms of chromatin compaction in quiescent cells 9:30 a.m. 10:00 a.m. Lorraine Pillus, UCSD Chromatin modifications influencing the cell cycle and dynamic cell aging 10:00 a.m. 10:15 a.m. Short talk From Submitted Abstracts 10:45 a.m. 11:00 a.m. Short Talk From Submitted Abstracts 11:00 a.m. 11:15 a.m. Short Talk From Submitted Abstracts 11:15 a.m. 11:30 a.m. Short Talk From Submitted Abstracts 11:30 p.m. 12:00 p.m. Business Meeting 12:00 p.m. 1:00 p.m. LUNCH 1:15 p.m. 3:15 p.m. Flash Talks 4:00 p.m. 7:00 p.m. GENERAL SESSION 8: Cell Cycle Control Chair: Brenda Andrews, University of Toronto 4:00 p.m. 4:30 p.m. Silke Hauf, Virginia Tech Robustness of chromosome segregation 4:30 p.m. 5:00 p.m. Eric Weiss, Northwestern University 5:00 p.m. 5:15 p.m. Dave Toczyski, University of California San Francisco Regulation of cellular biology by ubiquitin 5:15 p.m. 5:45 p.m. COFFEE BREAK 5:45 p.m. 6:00 p.m. Short Talk Selected From Submitted Abstracts 6:00 p.m. 6:30 p.m. Adam Rudner, University of Ottawa 6:30 p.m. 6:45 p.m. Short Talk From Submitted Abstracts 7:00 p.m. 8:00 p.m. DINNER 8:00 p.m. 10:00 p.m. POSTER SESSION 3 Catch-up poster session: all posters presented

Friday, July 20, 2018 9:00 a.m. Boxed Snacks to Go and DEPARTURES END OF CONFERENCE For additional information contact: FASEB Science Research Conferences 9650 Rockville Pike Bethesda, MD 20814 www.faseb.org/src