Managing your Research Career. Basic Sciences

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Faculty Development Day 2015 Managing your Research Career Basic Sciences Learn about setting up a basic science lab, regulatory issues, staffing your research team, publishing your research, and balancing research with other academic demands (teaching and service).

Mike Evans setting up a basic science lab, regulatory issues Tamara Alliston staffing your research team Sabrina Ronen publishing your research Tejal Desai balancing research with other academic demands (teaching and service) addressing your questions and concerns

Setting up a Basic Sciences Lab

Authorizations: Starting up Your Lab BUA: Biological Use Authorization IACUC: Animal Protocol CSA: Controlled Substance Authorization CUA: Chemical Use Authorization RUA: Radioactivity Use Authorization Meet the officers personally to establish a rapport and review the submission process Consult established investigators for boilerplate language Prioritize the submissions (i.e. BUA first, then more esoteric authorizations) Do it yourself the first time, then delegate

Starting up Your Lab Hiring: Consult HR to understand the rules regarding each category of employee at UCSF (SRA, postdoc, graduate student, specialist, etc) Thoroughly vet the terms of employment, reappointment, and separation For academic hires, solicit applications from your peers in the field first, then list advertisements online. Call all of the candidate s references, and be direct with your questions Be patient

Managing personnel: Starting up Your Lab Establish your expectations about performance before hiring Be detailed about expectations and overall job description in the offer letter Maintain consistent contact, either with regular individual meetings or group meetings Document performance (good and bad) in emails If notable performance concerns arise, consult HR immediately

Starting up Your Lab Purchasing: Develop a rapport with your post-award analyst Establish regular meetings with the post-award analyst, and/or study your monthly BSRs Contact sales representatives to learn of discounts for new investigators (Fisher, Thermo) Reach out to your peers to identify partners for purchasing medium sized equipment Utilize RAP to partially subsidize equipment purchases

Starting up Your Lab Grant-writing: Familiarize yourself with PIVOT to identify public and private funding mechanisms Enroll in the LSO listserv to get advanced notice about Young investigator opportunities Identify the YI awards that do not limit the number of submissions per institution (NIH DPs, NSF CAREER, DOD Exploratory or Idea Development Awards) Utilize RAP (high success rate for pilot awards) Ask your pre-award analyst to get redacted copies of successful applications from other UCSF investigators

Starting up Your Lab Grant-writing: Avoid NIH R21s unless you have a large body of preliminary data Solicit several letters of support for public RFAs Get to know your scientific and program officers-call them for advice before submitting an application, and after receiving your score/summary statement for resubmissions

Staffing a Basic Sciences Lab

Matushiq Sotak.

Others: Med/Dental Students Residents Fellows Volunteers Summer Students Lab Helper Matushiq Sotak.

Match Needs to the Person you Hire - Creativity vs. work - Stage of project development - Risk - Intellectual leadership - Project duration - Funding opportunities

Staffing Considerations for New Faculty Capacity: Access to Talent: Time Investment: Costs: Flexibility: Project Leadership: Post-doc >> Tech > Student* Student > Post-doc Student > Post-doc > Tech Similar, except fellowship Technician Post-doc > Student > Tech

Hiring a Technician Key Considerations: Service Provider vs. Project Ownership, Independence, Culture Career Tech: Experienced, Seeks success in this role 2 Year Tech : Recent graduate, aims to pursue advanced degree, etc. CAREER TECH 2 YEAR TECH PRO CON PRO CON Technical Expertise In the system Motivated Training Required Maturity Education Maturity Managerial Experience Open-minded Stability Short-term Turnover Divided Focus (MCAT, Interviews)

Publishing your Research

When to publish? Show productivity steady stream of publications Show high impact probably requires a long term study probably with a larger team Consider priorities of co-authors - first author (student who needs to graduate?) and other members of the team and collaborators Consider competition will you be scooped? Consider needs of an upcoming grant do you want to show peer reviewed expertise, do you need to show productivity on a renewal?

Authorship? Order of authorship in your lab: you are the senior author but if there is any question around order of authorship within your team resolve this quickly and avoid tensions. Also try to make clear who is driving the project (and be generous). Order of authorship in a collaborations: as much as possible try to discuss and decide upfront. Manuscript with a previous mentor: a transition period and/or continued collaborations are ok but make sure to have enough publications to show independence (new field or clear break)

Where to publish Open access versus traditional journals? Open access - now available through UC s escholarship website for all publications and is required by NIH after one year Cost - Open access journals always require payment, traditional journals may or may not Speed - now probably comparable since most journals publish online ahead of print Impact - variable in both cases

Balancing research with other academic demands

Balancing research with other academic demands (teaching and service) Balance will depend on series (outstanding in all or some categories) Balance will evolve over time with rank and step Balance will (initially) depend on department Discuss and take advice from: Chair UCSF mentor Outside mentors Colleagues

Balancing research with other academic demands (teaching and service) During the early steps of the Assistant rank consider whether the contribution to teaching and service can be slightly more limited while the major focus is on establishing a solid well funded research program. Consider: Time commitment (remember prep time) Benefits Examples: a few lectures in class; recruiting new students CME accredited courses; build reputation organizing dep. seminars; exposure to new research review seed grants; exposure to research and review

Balancing Other Aspects How much to travel? Being present on campus and at home but building national reputation and visibility Are all grants created equal? Individual grants versus larger collaborative or center grants Federal vs. Industry or Foundation LAST BUT NOT LEAST, WORK-LIFE BALANCE

Mike Evans setting up a basic science lab, regulatory issues Tamara Alliston staffing your research team Sabrina Ronen publishing your research Tejal Desai balancing research with other academic demands (teaching and service) addressing your questions and concerns