Biosafety in Liberia 1

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Biosafety in Liberia 1

THE LONG ROAD TO ZERO No NEW CONFIRMED CASES IN LIBERIA The Ebola Virus Disease was first confirmed in Liberia in March 2014. The first case was identified in Foya Lofa County border with Guinea. The EVD epidemic started with imported case from Guinea in March 2014 and in May 2014 from Sierra Leone. Liberia remains the worst affected country in terms of the highest number of EVD reported cases and deaths out of the current 6 affected countries in West Africa. Declared EVD Free 4

The journey to zero was difficult and took many lives The total cumulative cases and deaths as of the week of May 9, 2015 : confirmed EVD cases: 3,150 Deaths : 4,785 378 healthcare workers were infected with EVD, and 192 deaths All counties in Liberia reported EVD cases at different times within the outbreak period We adjusted and adopted various strategies across the thematic areas to get to Zero 5

Laboratory Hurdles Lab technicians abandoned their posts Staff at the NPHRL were stretched thin in numbers No formal sample transportation system No standard operating procedure or written communication strategy. No training in labeling samples and sample collection procedures. Lack of Triple packaging system Disconnect in reporting results 2 analysis site conducting DNA analysis. No training on post-mortem sample collection Minimum coordination and supervision of various diagnostics EVD laboratory to ensure biosecurity of samples

CoordinaLon, Control and Command NaLonal ConsultaLve Group President Inter- Ministerial Group Montserrado - IMS PACE Incident Management System (IMS) Chair and Deputy IMS Medical Response/Planning IMS Support Laboratory Epi- Surveillance Social Mobilisa<on Contact Tracing Case Management Logis<cs Opera<ons Finance/ Procurement M and E Planning Psychosocial CommiCee Dead Body Management UN CLUSTER SYSTEM 7

EXPANDED TESTING FOR SUSPECTED CASES AND DEAD BODIES Ruling Out EVD THE FEW LABORATORY TECHNICIANS OVER STRETCH WITH TESTING The <ming for specimen collec<on, tes<ng and disclosure of Lab results improved with the establish of mobile labs at strategic loca<ons in the country Prompt isola<on,management of cases,burial and contact tracing was made possible with tes<ng results delivered on <me. The staffs were trained to manage tes<ng 8

INFECTION PREVENTION AND CONTROL Monitor, regulate, and enforce IPC standards in all public and private facili<es Con<nue training staff in schools and maintaining supply chains for hand washing equipment, thermometers, and other screening and preven<on tools Ensure <mely referral of all febrile cases for tes<ng and treatment DEEPENED COMMUNITY ENGAGEMENT Strategies for Maintaining Zero Con<nue community involvement efforts (near and across borders ) to sustain gains and minimize resistance Prevent new cases and support health- seeking behaviors Use social mobiliza<on strategies to encourage ongoing vigilance 9

Labs Pre and Post Ebola (N=6) BIOSAFETY ISSUES Before AVer Biosafety Hoods 5/6 5/6, 1 opera<onal, 0 cer<fied Biosafety Manual None None Inventory Management Logs None None Sharps Containers Scanty Scanty Biosafety Officer None None Sample Storage Space 2/6 2/6 Biosafety Training 1/6 1/6

Biological Hazard MiLgaLon Elimina<on or Subs<tu<on of Hazard Highest Priority Engineering Controls Training Personal Protec<ve Equipment Mi<ga<on steps against EXPOSURE. Mi<ga<on steps against DISEASE ONSET. Occupa<onal Health Surveillance Vaccina<on (If available)

Issues to Address - Needs to consider high vs low risk (Does it include lab techs?) - Health workers responsible for best judgment for PPE u<liza<on - In a resource- limited segng, how do we address con<nued access to inventory - Baseline requirements for governments to meet in ensuring safety

Overarching Issues Senior management support Safety culture Inventory Management Legislation and Regulation Education and competency Oversight