REQUEST FOR PROPOSALS

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REQUEST FOR PROPOSALS Review Draft Patent Applications derived from Workshops for the Accelerated Development of Patents in Panama Carried Out by CAF and SENACYT and Preparation and Submission of Applications through the National Intellectual Property Office (DIGERPI) and the PCT CAF development bank of Latin America is a regional multilateral development agency that promotes a sustainable development model through credit operations, grants and technical assistance, and provides financial structuring of projects in the public and private sector of Latin America and the Caribbean. CAF has proposed a disruptive approach, its Patents for Development Regional Initiative, in order to accelerate the development of patentable technologies in the region, especially aimed at increasing hightech exports and royalty s receipts derived from licensing its industrial property. During the implementation of its Patents for Development Regional Initiative, CAF has developed an effective training method or tool to accelerate technology conceptualization and corresponding patent application preparation: CAF s Method of Accelerated Patent Development. This method has been tested at several intensive training workshops in the Panama, Colombia (Medellin), Paraguay (Asunción), and Mexico (Monterrey). In Panama, the three workshops carried out by CAF and SENACYT the last 12 months have generated over 300 draft patent application. Of these, around 80 have been registered in through the National Patent Office (DIGERPI) and 51 of those through the PCT. CAF invite you to present a proposal for the registration of up to 114 patent applications through the National Patent Office (DIGERPI) and through the PCT. 1 GENERAL INFORMATION 1.1 Terms of Reference of the Service Required The terms of reference of the services required are in Annex 1. 1.2 Submission of Proposals

Proposals must be sent in digital format (PDF) by email to patentes@caf.com by July 31 th, 2017 5:00pm, Panama time. Furthermore, one (1) physical copy of the proposal with a digital copy (USB Memory, CD, or DVD) must be directed to CAF development bank of Latin America, to the following address: Boulevard Pacífica P.H. Oceanía Business Plaza Torre 2000 piso 27 Punta Pacífica Código postal 0832, Ciudad de Panamá. Please note that all proposals must be sent via email digital format (PDF) and must include a scanned copy of the shipping guide (voucher) (DHL, UPS and Fedex are recommended services). In case of direct delivery of the physical copy of the proposal, an acknowledgment receipt from the corresponding CAF office. 1.2 Funding Body The funds to carried out the work are from the Science and Technology Secretary of Panama (SENACYT) that are being administered by CAF. 1.3 Schedule for the Submission of Proposals June 30th, 2017 July 14th, 2017 July31th, 2017 August 1th -6th, 2017 August 7th, 2017 August 21th, 2017 (*tentative) Request for Proposals available to Intellectual Property Agents, Start date for IP agents inquiries Deadline for the reception of inquiries Deadline for the reception of proposals (all the material) Period for the evaluation of the proposals Communication of the results Estimated date for contract signature 1.4 Inquiries Related to the Submission of Proposals All inquiries related to the Request for Proposals shall be directed to the following email: patentes@caf.com. 1.5 Expected Profile of Consultants/IP Agent Experience in the preparation and submission of PCT applications for the private sector; Experience in the preparation and submission of PCT applications for public and private universities; Experience in the preparation and submission of PCT applications for public and/or private Latin American universities;

Experience in the review and preparation of patent applications in Spanish to be submitted through National Patent Offices in Latin America; Experience in the review and preparation of patent applications to be submitted through the PCT in English utilizing the USPTO as the International Searching Authority; Capacity of reviewing descriptive memory drafts and preparing up to 40/month patent applications in Spanish and/or in English; Capacity of communicating with draft patent owners in Spanish; Capacity of preparing patent applications in English; Experience of submitting patent applications through the Panamanian National Patent Office (DIGERPI); The IP agent to be retained must have an IP correspondent or agent in Panama in order to represent the patent owners (i.e., companies, universities and research centers) before the National Intellectual Property of Panama (DIGERPI) and to help in obtaining all necessary authorizations and powers of attorneys to carry out the registrations via PCT. 1.6 Estimated Budget and Time for Carry Out the Work The total budget for the service of registration of up to 114 patent applications through the National Patent Office (DIGERPI) and through the PCT is US$ 800.000 (approximately US$ 7.000 per application) (please see Annex 1 for more details). The work must be carried out within six (6) months starting from the date of signature of the contract. 2 PREPARATIONS OF PROPOSALS The proposals must include: 2.1 Legal and Administrative Documents a) Letter of Submission of the Proposal. According to Form B-1 (Annex 2) b) Curriculum Vitae of the proposed team. Accordance with Form B-2 (Annex 3) c) Letter of Presentation of the Economic Proposal Form B-3 (Annex 4) d) Supplier full registration form legal person (Annex 5) e) Copy of the document that constitutes of the company (main contractor), where is stated the legal responsibility of the company representative f) Copy of the passport of the legal responsible/representative of the company (main contractor)

g) Copy of the document where the current legal responsible/representative of the company (main contractor) is entitled or signed in h) Copy of the document where the Board is constituted and the current members are signed in In case that any change in the proposed personnel that will carried out the work is necessary, the replacement personnel must have the same or greater experience than originally proposed. Any personnel changes must be approved in advance by CAF. 2.2 Technical Proposal The technical proposal should include the requeriments established in the Terms of Reference attached to these guidelines (see Annex 1), as well as a detailed description of the work plan to be implemented, identifying the main milestones of the service. 2.3 Economic Proposal The total cost of the proposal must be presented in United States Dollars (USD), and the payments will be made in the same currency. The payment method will be made upon delivery of the products established in the Terms of Reference and the conditions stipulated in the contract, to be signed between CAF and the selected Consultant, once they have been approved by CAF. The economic proposal must be submitted according to Form B-3 and must be sent in a sealed envelope separate from the other components of the proposal. It must also be sent via email. 3 QUALIFICATION CRITERIA For the qualification of the technical proposal, a maximum of 100 points will be considered. The qualification will be assigned according to the proposal, as follows: 3.1 Technical Proposal and Work Team (100 Points) It refers to how the Consultant will develop the theme and will use the technical resources to obtain the products. We will evaluate how the Consultant will elaborate the methodological processes that it considers necessary for the development of the consultancy, including the quality insurance of the services plan.

The team of consultants should be composed by professionals who possess academic training and experience in the areas of knowledge applied to the work. In particular, the technical proposals will be evaluated as follows: Selection/Evaluation Criteria Top Score 1. Experience 50 1.1. Experience in the preparation and submission of PCT applications for the private sector 5 1.2. Experience in the preparation and submission of PCT applications for public and private universities 5 1.3.. Experience in the preparation and submission of PCT applications for public and/or private Latin American universities 5 1.4. Experience in the review and preparation of patent applications in Spanish to be submitted through National Patent Offices in Latin America 15 1.5. Experience in the review and preparation of patent applications to be submitted through the PCT in English utilizing the USPTO as the International Searching Authority; 10 1.6. Experience of submitting patent applications through the Panamanian National Patent Office (DIGERPI) 10 2. Resources 50 2.1. IP correspondent or agent in Panama 30 2.2. Professional and technical personnel proposed 20 Total 100

ANNEX 1 Terms of Reference Review Draft Patent Applications derived from Workshops for the Accelerated Development of Patents in Panama Carried Out by CAF and SENACYT and Preparation and Submission of Applications through the National Intellectual Property Office (DIGERPI) and the PCT (30/06/2017) 6

1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Millones de dólares Introduction Public (and private) research and development investments in Latin American and Caribbean countries in the last decades have not contributed to an increase in the following indicators associated with technology development: High technology exports Royalties receipts from the licensing of intellectual property Granted patents by the USPTO and EPO to Latin American and Caribbean countries nationals and residents Patent Applications through USPTO, EPO and PCT system by Latin American and Caribbean countries This can be appreciated in the following four figures. High Technology Exports by regions (in million US$) 1.200.000 1.000.000 800.000 600.000 Asia Europa Norteamérica América Latina y el Caribe 1.078.631 678.776 400.000 200.000 0 226.421 13.743 Años

1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 Número de patentes concedidas Millones de USD Royalties received in Regions from the licensing of intellectual property (in million US$) 160.000 140.000 120.000 100.000 80.000 60.000 40.000 20.000 0 Europa Norteamérica Asia América Latina y el Caribe 137.323 129.312 50.361 994 Años Granted patents by the USPTO by Regions 160.000 140.000 120.000 100.000 80.000 60.000 40.000 20.000 0 Norteamérica Asia Europa América Latina y el Caribe 147.943 83.799 47.138 578 Años

1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Número de solicitudes vía PCT 120.000 100.000 80.000 60.000 40.000 PCT Applications by Regions Asia Norteamérica Europa América Latina y el Caribe 106.709 59.058 58.054 20.000 0 1.481 Años In this context, CAF development bank of Latin America has proposed a disruptive approach, its Patents for Development Regional Initiative, in order to accelerate patentable technological development in the region, especially aimed at increasing high-tech exports and royalty s receipts derived from licensing its industrial property. The main objectives of CAF`s Regional Patent Initiative are: Contribute to an accelerated increase in the very short-term of the volume of patents generated by Latin American countries through PCT, USPTO, and EPO Establish patentable technology incubators/accelerators in the region Support governments and other institutions in member countries in defining strategies for accelerating the development of patentable technology Contribute to increase royalty receipts and high technology exports from the LAC region in the medium - long term CAF`s Initiative also has the following characteristics:

CAF s patent initiative is a regional program that is complementary to the science, technology and innovation programs of member countries The initiative aims to decouple scientific activities from technology development and innovation activities, allowing people without third and fourth educational level to participate in technological development The initiative proposes the generation of patent applications before engaging in research and development activities in laboratories The initiative proposes the generation of engineering and software technology patents that not necessarily require formal education, empowering more people to patent quickly Key elements of the Initiative are: 1. It proposes to divide the identification/conceptualization of patentable technologies in two areas: Development of patentable technological solutions to problems identified from now on; and Development of new markets through patented technologies 2. It proposes to lower the patent prosecution costs through a low bono program with IP agents that considers training the inventors, researchers and innovator to prepare well written patent applications 3. It considers that patent applications must have a minimum geographical coverage of one billion people (including always the US, and Europe) 4. It strongly recommends that before starting any patenting process, market research and technological prospecting should be done During the implementation of its Patents for Development Regional Initiative, CAF has developed an effective training method or tool to accelerate technology conceptualization and corresponding patent application preparation: CAF s Method of Accelerated Patent Development. CAF is in the

process of registering this method. This method has been tested at several intensive training workshops in the region and has achieved the following results: Between 2016 and 2017, ten intensive workshops were held for the accelerated development of patents in four countries: Panama, Colombia (Medellin), Mexico (Monterrey) and Paraguay (Asuncion) were 410 professionals were trained and 500 descriptive memories of technological concepts were obtained with the possibility of patenting. Over 80 patent applications have been submitted in Panama`s National Intellectual Property Office (DIGERPI) and 52 PCT patent applications submitted through the International Bureau of WIPO. In just in six months of intervention CAF helped a pilot Latin American public university to become the first Latin American university to be among the top 50 universities in the world generating applications via the PCT 1. Also within a year (2016), CAF has strengthened Panama s capacity for patent applications generation (both national and via PCT), converting Panama the first generator of patent applications via PCT per million inhabitants in Latin America (with over 15 PCT patent applications per million inhabitants) 1 51 patent applications were developed and submitted to PCT by the Universidad de Panama (UTP) between September-November 2016 including a request for early publication. These PCT applications were published by WIPO between January and March 2017. The Universidad Tecnologica de Panama (UTP) should be in the list of the top 50 universities that submit PCT applications in the Patent Cooperation Treaty Yearly Review of 2017 that will be published mid 2018

Solicitudes PCT por millón de hab. 16 Panamá Chile 15 14 12 México Brasil 10,9 10 8 6 4 2,8 2 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 Años 2,2 In 2016 CAF and the Science, Technology and Innovation Secretary of Panama (SENACYT) signed a MOU and a Specific Accord in order for CAF to help strengthening Panama`s capacity to generate patentable technologies and register them internationally, especially through PCT, the USPTO and EPO offices. The objective of the Specific Accord was that CAF would help to register both in Panama`s National Intellectual Property Office (DIGERPI) and through the PCT up to 114 draft patent applications generated in the Workshops for the Accelerated Development of Patents delivered in Panama by CAF and SENACYT during 2016-2017. For this objective, SENACYT transferred to CAF the amount of US$ 800,000. Objective of the Services to be retained The objective of the service is the registration of up to 114 patent applications generated during CAF`s Workshops for the Accelerated Development of Technological Patents through the National Intellectual Property of Panama (DIGERPI) and through the PCT. Description of the Services to be retained

The services to be retained would include the following: a) To review (in Spanish) of the descriptive memories of technological concepts (draft patent applications) provided by CAF including the summaries in the corresponding cases; b) For each draft patent application reviewed, to carry out a preliminary prior art search and to make an opinion about its novelty; c) For each draft patent application reviewed that it is considered novel, to write or reformulate the claims (minimum 5 claims) as appropriate. d) For each draft patent application reviewed that it is considered novel, to write the abstract; e) For each draft patent application reviewed considered novel, to review the drawings, generating regulatory drawings, if necessary; f) To prepare and submit (in Spanish) the reviewed patent applications through the National Intellectual Property of Panama (DIGERPI) were the draft patent application were generated; g) To translate into English the texts of the patent applications submitted through the National Intellectual Property of Panama (DIGERPI); and h) To prepare a PCT application based on the patent applications translated into English and deposit in the World Intellectual Property Organization (WIPO). For this step, consider the USPTO as the International Searching Authority i) For all the above steps and activities, work with the IP correspondent or agent in Panama in order to represent the patent owners (i.e., companies, universities and research centers) before the National Intellectual Property of Panama (DIGERPI) and to help in obtaining all necessary authorizations and powers of attorneys to carry out the registrations via PCT Additional Requirements of the Services to be retained Experience in the preparation and submission of PCT applications for the private sector;

Experience in the preparation and submission of PCT applications for public and private universities; Experience in the preparation and submission of PCT applications for public and/or private Latin American universities; Experience in the review and preparation of patent applications in Spanish to be submitted through National Patent Offices in Latin America; Experience in the review and preparation of patent applications to be submitted through the PCT in English utilizing the USPTO as the International Searching Authority; Capacity of reviewing descriptive memory drafts and preparing up to 40/month patent applications in Spanish and/or in English; Capacity of communicating with draft patent owners in Spanish; Capacity of preparing patent applications in English; Experience of submitting patent applications through the Panamanian National Patent Office (DIGERPI); The IP agent to be retained must have an IP correspondent or agent in Panama in order to represent the patent owners (i.e., companies, universities and research centers) before the National Intellectual Property of Panama (DIGERPI) and to help in obtaining all necessary authorizations and powers of attorneys to carry out the registrations via PCT. Cost of the Services to be retained The form of payment will be: 15% after the signing of the contract; and Up to six monthly payments reflecting the amount derived from: a) the number of previous art searches carried out the corresponding month; b) the number of reviews of draft applications that survived the previous art search carried out the corresponding month;

c) the number of applications submitted though the DIGERPI carried out the corresponding month; and d) the number of applications translated into English and submitted though the PCT carried out the corresponding month. CAF will cover: US$ 400 for the prior art search for each patent reviewed and the giving of an opinion about its novelty; US$ 6,600 for each patent reviewed considered novel and submitted through the National Intellectual Property of Panama and its translation into English and submitted through the PCT system. This unit cost per patent application (i.e., US$ 6,600) will cover, among others: 1) The fees to submit the application through the National Intellectual Property of Panama 2) The fees 2 to submit the patent application through the PCT 3) The fee for early publication in the PCT 4) The honorary to review the applications in Spanish, to translate into English the patent applications submitted through the National Intellectual Property of Panama In order to handle the uncertainty related to how many applications will be registered without knowing how many draft concepts will survive the prior art search, consider the following table: 2 Application fees, transmission fees and international search report fees. All patent applications are expected to be below 30 pages

Number of Draft Concepts to be reviewed Cost of prior art search per concept (US$/concept) Total Cost of prior art search (US$) Percentage of survival of prior art search Number of reviewed concepts that survive prior art search Unit cost of registration through DIGERPI and PCT of reviewed concepts that survive prior art search (US$/concept) Total cost of registration through DIGERPI and PCT of reviewed concepts that survive prior art search (US$) Total cost of prior art seach and registration through DIGERPI and PCT of reviewed concepts that survive prior art search (US$) 114 400 45,600 100 114 6,600 752,400 798,000 119 400 47,600 95 113 6,600 746,130 793,730 126 400 50,400 90 113 6,600 748,440 798,840 133 400 53,200 85 113 6,600 746,130 799,330 140 400 56,000 80 112 6,600 739,200 795,200 149 400 59,600 75 112 6,600 737,550 797,150 159 400 63,600 70 111 6,600 734,580 798,180 170 400 68,000 65 111 6,600 729,300 797,300 183 400 73,200 60 110 6,600 724,680 797,880 198 400 79,200 55 109 6,600 718,740 797,940 215 400 86,000 50 108 6,600 709,500 795,500 237 400 94,800 45 107 6,600 703,890 798,690 263 400 105,200 40 105 6,600 694,320 799,520 295 400 118,000 35 103 6,600 681,450 799,450 336 400 134,400 30 101 6,600 665,280 799,680 390 400 156,000 25 98 6,600 643,500 799,500 465 400 186,000 20 93 6,600 613,800 799,800 Schedule of the Services to be retained CAF preliminarily estimates the following time schedule per each draft patent application review: One week for the prior art search for each patent reviewed and the giving of an opinion about its novelty; One week for the review in Spanish each draft patent that is considered novel One week for preparing and submitting the patent application for each patent reviewed in Spanish through the National Intellectual Property of Panama One week to translate into English the patent application submitted through the National Intellectual Property of Panama

One week for preparing and submitting the patent application for each patent translated into English through the PCT system.

ANNEX 2 FORM B-1 LETTER OF SUBMISSION OF THE PROPOSAL (Date) Dear Corporación Andina de Fomento CAF Ref. (Indicate the subject of the contract) Dear Sirs: We declare and warrant having carefully examined the Guidelines for the Submission of Proposals with date [---], as well as the forms for the submission of the proposal and we hereby accept without reservation all the provisions of those documents. (Indicate name of the company) offers to execute the studies in the conditions required in the Guidelines for the Submission of Proposals and according to the forms of the proposal presented. This proposal has a 90 day validity period beginning from the date set for the Opening of Proposals. We declare the veracity of all the information provided and hereby authorize, in case of adjudication, any natural or legal person, to supply to the authorized representatives of CAF, all the information they deem necessary to verify the documentation that we present. In case of falsehood, we are notified that your entity has the right to disqualify our proposal. If our proposal is accepted, we commit ourselves to submit, within the deadline established in the Guidelines for the Submission of Proposals, the original documents or legalized photocopies of each and every one of the documents indicated in the proposal forms, as well as all documents we present in photocopy.

If we are selected to carry out the studies, this proposal will constitute a binding commitment until the contract is prepared and signed. (Signature of Legal Representative) (Name and Position of Legal Representative)

ANNEX 3 FORM B-2 CURRICULUM VITAE OF THE PROPOSED TEAM (Please fill one form per specialist) POSITION: Complete Name: Age: Nationality: Profession: Specialty: Activities that the specialist will perform in the study: EXECUTED SERVICES THAT CAN BE EVALUATED DESCRIPTION OF NAME OF POSITION EXECUTION PERIOD THE SERVICE CUSTOMER START END (MM/YY) (MM/YY) Note: Performed evaluable services are understood to be those works performed that have characteristics or are closely similar to the service that will be performed by the professional, performed in the last five (5) years.

The undersigned, (name of the professional), I undertake to carry out the proposed activities in the event that the Consultant (name of the Consultant) is awarded the Contract object of this call. (Signature of the Specialist) (Signature of Legal Representative)

ANNEX 4 FORM B-3 LETTER O FPRESENTATION OF THE ECONOMIC PROPOSAL Dear Corporación Andina de Fomento CAF (DATE) Ref.: (Name of the Study) Dear Sirs, In accordance with the Guidelines for the Submission of Proposals with date [---], and all the information contained therein, our company (name of company) offers the consultancy services to (indicate the subject of the consultancy) for the total amount of the Cost of Services, which is: (please write both in numbers and figures the total value). We declare and warrant that we have carefully examined the Guidelines for the Submission of Proposals as well as the forms for submitting the proposal and we hereby accept unreservedly all the provisions of those documents. Until the final Contract is processed, we will recognize as mandatory documents the proposal and the written acceptance by CAF. (Signature of the Legal Representative)

(Name and Position of Legal Representative)

ANNEX 5 SUPPLIER FULL REGISTRATION FORM LEGAL PERSON BASIC INFORMATION Name or Company name (*): Trade name (if different from Company name): Company Purpose (only for Companies) (*): Address (*): City (*): Zip code: Country (*): Telephone number (*): Email (*): Fax number: Website: TAX INFORMATION Tax ID number (legal person) (*): Mail address (if different from that mentioned above): CONTACT INFORMATION (only for Companies) Full name (*) Job title / Department (*) Email (*) Telephone Number (*) Mobil Number (*) PRODUCTS AND SERVICES PROVIDED (*) COUNTRIES OF OPERATION (if different from those mentioned above) (*) MAIN CLIENTS (*) Client s name (*) Country (*) Briefly describe the main criteria used when selecting clients (*): MAIN SUPPLIERS Supplier s name Country

Briefly describe the main criteria used when selecting suppliers (*): LEGAL REPRESENTATIVE, BOARD OF DIRECTORS AND SHAREHOLDERS DATA (who have direct or indirect control of 10% or more of the shares of the entity - only for Companies) Full Name (*) Nationality (*) Tax ID or Passport No. (*) Specify if Shareholder or otherwise indicate Job Title(*) % shares (*) Shareholde r since (specify date) (*) Government or Political Responsibilities Yes / No Duty Period CONTROLS AND / OR REGULATIS (only for Companies) (*) Is the company regulated by any organization? (*) Yes No If yes, indicate organization s name: Is the company audited by an independent company? (*) Yes No If yes, indicate name of auditor s firm:

ANNEX 6 Contract Table of Content Example AGREEMENT between Corporación Andina de Fomento ("CAF") and NAME OF COMPANY ("Consultant ) To carry out the following service Review Draft Patent Applications derived from Workshops for the Accelerated Development of Patents in Panama Carried Out by CAF and SENACYT and Preparation and Submission of Applications through the National Intellectual Property Office (DIGERPI) and the PCT

Contents First: Purpose Second: Term Third: Location of the Contract and Performance of Activities Fourth: Cost of Services Fifth: Conditions / Form of Payment Sixth: Taxes Seventh: Logistics Eight: Supervision Ninth: Modifications of the Consultant Tenth: Property and Reserve Eleventh: Independent Contractor Twelfth: Successors and Assignees Thirteenth: Conflict of Interest and Ethical Standards Fourteenth: Indemnity Fifteenth: Removal of Consultant Sixteenth: Notice Seventeenth: Reports Eighteen: Standard of Care Nineteenth: Representations and Warranties of the Consultant Twentieth: Amendment Twenty-First: Severability Twenty-Second: No waiver; Cumulative Remedies Twenty-Third: Validity and Dispute Resolution Twenty Fourth: Privileges and Immunities Twenty Fifth: Counterparts Twenty Sixth: Further Assurances Twenty Seventh: Destinations of the Funds Twenty-Eight: Other Agreements or Communications Twenty-Ninth: Limitation of Liability Thirty First: Force Majeure