Malaria surveillance, monitoring and evaluation manual

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Malaria surveillance, monitoring and evaluation manual Abdisalan M Noor, Team Leader, Surveillance Malaria Policy Advisory Committee (MPAC) meeting 22-24 March 2017, Geneva, Switzerland

Global Technical Strategy for Malaria 2016-30 Irrespective of where countries are on the path to elimination, surveillance of malaria should be upgraded to a core intervention in national and subnational malaria strategies. Global Technical Strategy for malaria 2016-2030

A framework for malaria elimination

Updated surveillance manual 1. Guidance from MPAC 2. Online approval in June or July 2017

What is new? the 2012 Control and Elimination operation manuals are combined into one document the revised manual is aligned with both the GTS 2016-2030 and the Elimination Framework 2017 the case and foci investigation forms will be automated and a section on foci mapping is included

What is new? new sections on surveillance in the private and community health sectors and migrant and mobile populations monitoring and evaluation of: national programmes the GTS surveillance systems

Chapter 1: Surveillance on the pathway to malaria elimination

Malaria surveillance across the continuum

Core principles of malaria surveillance 1. Integration of surveillance systems with HIS 2. Accurate diagnosis of malaria 3. Alignment of SoPs with WHO recommendation & regulation to make malaria notifiable 4. Stratified surveillance for heterogeneous epidemiology 5. Investments in surveillance prior to transition of epidemiology 6. Near real time reporting during elimination 7. Empowerment of frontline staff 8. Linking surveillance to response 9. Surveillance in all sectors (private, community, MMPs etc) 10. Continued efforts post elimination 11. Surveillance and innovation 12. Monitor the surveillance system s performance

Chapter 2: Concepts and practice of malaria surveillance systems 1. Case definitions 2. Case detection 3. Case investigation 4. Case classification 5. Foci investigation and mapping 6. Foci classification 7. Foci response

Case classification

Foci classification

Active case detection process

Chapter 3 Establishing surveillance systems

Health information cycle

Health information cycle Recording clearly defined essential indicators diagnosis Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) system for data recording - Patient and laboratory registers/forms/cards, tally sheets, pens, computers, databases software, printers training materials and SoPs

Health information cycle Recording Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) Reporting data compilation data quality and completeness verification data transmission data archiving system manuals and SoPs

Health information cycle Recording Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) Reporting Analysis relevant analytical skills and data quality checks hardware and software standard analytical plan and expected products e.g. charts, surveillance bulletin etc.

Health information cycle Recording Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) Presentation Reporting Analysis hardware and software for data display agreed format for data presentation targeted different audiences communication meetings etc

Health information cycle Recording completeness of data and reporting frequencies Interpretation and Evaluation Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) Reporting Analysis data quality checks system performance and bottlenecks performance of staff tasked with managing the system Presentation assessment of trends of key indicators

Health information cycle Dissemination and Use Interpretation and Evaluation Recording Human Resources (the patients and communities whose details are registered, the health facility staff who gather and/or use the data and decision-makers both inside and outside the health service who use data ) Presentation Reporting Analysis develop mechanisms of dissemination of data to stakeholders use data for decision making at country level use data for quantification and forecasting resource needs use data to respond to epidemics and other threats tracking progress towards elimination supervision and feedback

Surveillance for elimination

Chapter 4: Use of surveillance, surveys and other data for monitoring and evaluation of national programmes and the GTS

Monitoring and evaluation process

SME indicators High transmission Low transmission Elimination/ prevention of re-establishment Sub-Saharan Africa Outside sub-saharan Africa International National Sub-national Routine reporting system Health facility survey Household survey Applicability of Indicator Transmission intensity Geography Level Data source Indicator Indicator Inputs Financing 1.1 Malaria expenditure per capita for malaria control and elimination 1.2 Funding for malaria relevant research o o 1.3 Number of top-10 registered corporations that invest in malaria Outcome Vector control 2.1 Proportion of population at risk sleeping under an insecticide-treated o net (ITN) or living in house sprayed by IRS in the previous 12 months 2.2 Proportion of population at risk that slept under an ITN the previous o o night 2.3 Proportion of population with access to an ITN within their household o o 2.4 Proportion of households with at least one ITN for every two people o o 2.5 Proportion of households with at least one ITN o o 2.6 Proportion of available ITNs used the previous night o o 2.7 Proportion of population at risk potentially covered by ITNs distributed o 2.8 Proportion of targeted risk group receiving ITNs o 2.9 Proportion of population at risk protected by indoor residual spraying o o 2.10 Proportion of targeted risk group receiving IRS Indicator highly relevant to setting o Indicator potentially relevant to setting Requires data from both routine systems and household survey

SME indicators High transmission Low transmission Elimination/ prevention of re-establishment Sub-Saharan Africa Outside sub-saharan Africa International National Sub-national Routine reporting system Health facility survey Household survey Applicability of Indicator Transmission intensity Geography Level Data source Indicator Indicator Inputs Chemoprevention 3.1 Proportion of pregnant women who received 3 doses of intermittent preventive therapy (IPTp) 3.2 Proportion of pregnant women who received 2 doses of IPTp o 3.3 Proportion of pregnant women who received 1 dose of IPTp o 3.4 Proportion of pregnant women who attended antenatal care (ANC) at o least once 3.5 Proportion of children aged 3 59 months who received the full number of courses of SMC per transmission season Case detection 4.1 Proportion of children under 5 with fever in the previous 2 weeks for o o whom advice or treatment was sought 4.2 Proportion of detected cases contacting health services within 48 hours of developing symptoms Diagnostic 5.1 Proportion of patients with suspected malaria who received a o testing parasitological test 5.2 Proportion of children under 5 with fever in the previous 2 weeks who o o had a finger or heel stick 5.3 Proportion of health facilities without stockouts of key commodities o for diagnostic testing Treatment 6.1 Proportion of patients with confirmed malaria who received first-line antimalarial treatment according to national policy 6.2 Proportion of treatments with ACTs (or other appropriate treatment o o o according to national policy) among febrile children <5 6.3 Proportion of P. vivax and P. ovale patients who received radical cure o o treatment 6.4 Proportion of health facility months without stockouts of first-line o treatments

SME indicators Surveillance 7.1 Proportion of malaria cases detected by surveillance systems 7.2 Proportion of expected health facility reports received o 7.3 Annual blood examination rate 7.4 Proportion of cases investigated and classified 7.5 Proportion of foci investigated and classified 7.6 Percentage of case reports received <24 hours after detection Impact Prevalence 8.1 Parasite prevalence: proportion of population with evidence of o o infection with malaria parasites Incidence 9.1 Malaria case incidence: number of confirmed malaria cases per 1000 persons per year 9.2 Malaria admission rate: number of malaria admissions per 10 000 o o persons per year 9.3 Malaria test positivity rate o 9.4 Proportion of admissions due to malaria o o 9.5 Number of foci by classification Mortality 10.1 Malaria mortality rate: number of malaria deaths per 100 000 persons o o per year 10.2 Proportion of inpatient deaths due to malaria o o Elimination 11.1 Number of areas/ countries that have newly eliminated malaria since 2015 Prevention of reestablishment 12.1 Number of areas/ countries that were malaria-free in 2015 in which malaria has been re-established Indicator highly relevant to setting o Indicator potentially relevant to setting Requires data from both routine systems and household survey

SME indicators 20 15 1. Malaria incidence rates 4. Diagnostic effort 4% Confirmed cases per 1000 Annual blood examination rate Inpatients per 10 000 Deaths per 100 000 3% 10 2% 5 1% - 2013 2014 2015 2016 0% 2013 2014 2015 2016 2. Proportional malaria incidence 5. Quality of diagnosis and reporting 80% 60% Slide positivity rate % Inpatients due to malaria % Deaths due to malaria 100% 80% 60% 40% 40% 20% 0% 2013 2014 2015 2016 20% % Health facilities reporting % Suspected cases tested 0% 2013 2014 2015 2016 3. General patient attendance 6. % Cases due to P. falciparum 250 200 Outpatients per 1000 Inpatients per 10 000 Deaths per 100 000 50% 40% % Cases due to P. falciparum 150 30% 100 20% 50 10% - 2013 2014 2015 2016 0% 2013 2014 2015 2016

Pending or incomplete sections 1. Surveillance of Plasmodium vivax 2. Entomological surveillance in burden reduction and elimination 3. Routine information systems high burden countries 4. Improved approaches to data use electronic tutorials, forms, annexes 5. Mapped examples for foci mapping 6. Surveillance systems assessments - electronic check lists and a sample questionnaire 7. Accompanying DHIS 2 modules (burden reduction and elimination) 8. Expanded section on epidemics

SM-TEG members Name Nationality 1. Adam Bennett USA 2. Arantxa Roca-Feltrer (Chair) Spain 3. Arnaud Le Manech France 4. Chris Drakeley (co-chair) UK 5. Erin Eckert USA 6. Jian-wei Xu China 7. John A. Painter USA 8. Kes Herdiana Indonesia 9. Khalid Abdelmutalab Elmardi Sudan 10. Laurence Slutsker - MPAC USA 11. Ndiop Medoune Senegal 12. Paola Marchesini Brazil 13. Saute Franscisco Mozambique

SME Manual revision - process Selection of SME TEG members Draft 1 - First SME- TEG meeting to discuss SME manual Draft 2 - Presentation to MPAC and circulation of SME manual to TEG and Regional Advisors Draft 3 of SME Manual - circulation to SME- TEG, GMP, Regional Advisors Draft 4 of SME manual - circulation to regions and selected countries NMCPs, MPAC chair and selected MPAC members Final version of SME manual and online approval by MPAC Dec 2016 Feb 2017 Mar 2017 April 2017 May 2017 June 2017