Performance of Tikur Anbessa Specialised Hospital: Cross sectional Study Dawit Teshome, AAU Aynoshe Adio, AAU Nov 16, 206 Dare es Salaam, Tanzania

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Performance of Tikur Anbessa Specialised Hospital: Cross sectional Study Dawit Teshome, AAU Aynoshe Adio, AAU Nov 16, 206 Dare es Salaam, Tanzania [DATE]

Thanks to our generous sponsors 12/27/2016 2

Outlines Introduction Statement of the problem Objective Method Results and Discussions Conclusion and Recommendation References 12/27/2016 3

Introduction Medicines are integral part to any healthcare system. They account 23.3% 33.2% of the total health spending countries globally. (WHO, 2010) Up to 90% of the population in developing countries purchase medicines out-of-pocket. This makes medicines the largest family expenditure item following food. (WHO and HAI, 2008) 12/27/2016 4

Introduction.cont d Limited access to essential medicines: undermines health systems objectives of equity, efficiency and better health service provision. aggravates irrational use of medicines which is a common problem in developing countries including Ethiopia. Proper management of pharmaceutical SC Improves access to essential medicines Minimizes wastage and ensures effective utilization of limited resources 12/27/2016 Increases program impact and enhances quality of care 5

Statement of the problems Evidences in Ethiopia shows that the pharmaceutical supply chain is not performing well Improving Supply Chain and Logistic Management is Strategic Objectives of FMOH in its Health Sector and Transformation Plan (2015/16-2019/20) Performance measures: 1. Increase availability of essential drugs for primary, secondary and tertiary healthcare to 100% 2. Reduce wastage rate to less than 2% 3. Increase proportion of essential drugs procured from local manufacturers from 25% to 60% 4. Reduce procurement lead-time from 240 days to 120 days 12/27/2016 6

Objective General Objective To assess pharmaceutical SCM performance of Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa, Ethiopia. Specific Objectives To explore how the pharmaceutical SCM operates in TASH To determine pharmaceutical SCM performance of TASH 12/27/2016 7

Method - Study Setting Tikur Anbessa Specialised Hospital (TASH), CHS, AAU 12/27/2016 8

TASH University Teaching Hospital Established in 1972 Provide Services to 700,000 patients per year through 77 case teams organized Outpatients (adult vs pediatrics) Emergency (adult vs pediatrics) In patients Surgery Professionals Number % Medical Doctors - Specialist 360 10.3% Medical Doctors - Sub - Specialist 92 2.6% Medical Doctors General practitioner 90 2.6% Residents 500 14.3% Intern 99 2.8% Medical students 1396 40.0% Midwifes 38 1.1% Nurse 730 20.9% Pharmacist 65 1.9% Other health professionals 124 3.5% 12/27/2016 9

Methods-Study Design and Data Collection Survey was conducted using qualitative and quantitative data collection Data was collected in May, 2016 In-depth interview was also held with Pharmacy Service Directorate Director; Medical Store Manager and Supply Chain Coordinator of the Hospital A Delphi technique was used to select medicines which indicate pharmaceutical supply chain performance of the Hospital 12/27/2016 10

Methods-Study Design and Data Collection The SC performance was assessed based on tools developed by USAID DELIVER project for public health managers. (Aronovich et al., 2010) Direct Observation was made at the main store of the Hospital Data were abstracted from Bin Cards, Report and Requisition Form, HIMS report and IFRR 12/27/2016 11

Methods- Data Analysis and Ethical Clearance Quantitative data were analysed by using simple descriptive statistics (mean, percentage and proportion) Qualitative data were also analysed by theme. Ethical approval was obtained from SoP, Addis Ababa University and management of the hospital. 12/27/2016 12

Results - Qualitative I. Qualitative Findings Description of Interviewee All respondents were Profession: Pharmacists (B. Pharm - M. Pharm) Age: 27-36 years Average work experience: 8.3 [6-11] years of work in the hospital 12/27/2016 13

Results - Qualitative cont d Pharmaceutical SCM operation of TASH Selections of Pharmaceuticals Medicines were selected by pharmacists based on TASH s list medicines (developed in 2012) Nevertheless, the list of medicines has not been updated for so long and it also considers almost all medicines as vital and essential.pharmaceutical SC coordinator Director of Pharmacy Service Directorate and DSM case team coordinator also prepare annual budget breakdown for different category of products last year we requested 134 million but we obtained ~ 22, million from the university. In the middle of the year, extra budget was mobilized from Ministry of Finance and stakeholders and procurement was made effective. This kind of budget shortage makes you unplanned. Director of Pharmacy 12/27/2016 14

Results- Qualitative cont d Pharmaceutical quantifications Drug and Supply Chain Management case team quantify pharmaceuticals mainly by using consumption method. However, this has lead the hospital to overlook new drugs and dosage forms that should have been included in the procurement list 12/27/2016 15

Results- Qualitative cont d Pharmaceutical Procurement DSM case team select, prepare specification and determine quantity of medicines to be procured. Procurement practice is initiated from the hospital after the securing approval from Clinical service Director Medicines are directly procured from PFSA. However, when there is stock out, the hospital rarely uses open procurement method and Request for Quotations The procurement is made by DSM procurement officer (pharmacist) and procurement officer (purchasing 12/27/2016 16 professionals)

Results- Qualitative cont d Transportation While Products for vertical program delivered directly by PFSA, products purchased through Revolving Drug Fund (RDF) delivered by the hospital vehicle. Absence of dedicated vehicle for the Hospital was major gap. 12/27/2016 17

Results- Qualitative cont d Pharmaceutical Distribution within the Hospital Distribution to each dispensing units was made every two weeks using IFRR Sometimes this schedule may not be functional when medications are unavailable in central medical store...store manager The hospital sends Report and Requisition Form (RRF) to PFSA monthly but they complained for not getting the requested type and amount of medicines. we always send report but we are not getting the requested amount and types of medicines from PFSA. This, in turn, is making our staff reckless in estimating quantities.sc coordinator 12/27/2016 18

Results- Qualitative cont d Table: Medical store operation of TASH, May 2015/16 Description Bin Cards are used & updated regularly Yes No X Labels, expiry dates, and/or manufacturing dates are visible. Products are stored & organized in a manner which hospital uses of FEFO Products are protected from direct sunlight at the of the SURVEY The storeroom is maintained in good condition (clean, no trash, sturdy shelves, and boxes well-organized). Storage area is secured with a lock and key Store manager is available during normal working hours Cartons and products are in good condition 12/27/2016 19 X X X X X X X

Results- Qualitative cont d How the hospital measure its Pharmaceutical SCM performance? No objective indicator was used to measure performance We measure our performance by comparing with the past. For instance, availability of medicines for this year has increased in both variety and quantity compared to last year. Improvement in inventory record keeping and implementing IPLS was also done. Moreover, we managed to reduce expire of medicines significantly SC coordinator 12/27/2016 20

S. No. S.No. 1 Acyclovir 200mg tab 18 Mannitol 20% 2 Adrenaline 0.1%/ml 19 Methyldopa 250mg x200 tabs 3 Amoxicilline 125mg/5ml susp. 20 Metoformine 500mgX100 tab 4 Atropine sulphate 1mg/ml 21 Metronidazole 5mg/ml ini. 5 Ceftriaxone 1gm inj. 22 Morphine 10mg/ml inj. 6 Cimetidine 200mg/2ml 23 NPH insulin 7 Dextrose 40% 24 ORS 8 Diazepam 5mg/ml inj. 25 Oxytocin 10IU inj 9 Dopamine 40mg/ml 26 Parcetamole 125mg supp. 10 Enalpril 10 mg x100 tabs 27 Phenobarbitone 30mg x100tabs 11 Furosemide 10mg /ml inj. 28 Plasil 5mg/2ml 12 Heparine 25,000IU/5ml 29 Regular insulin 13 Hydralazine 20mg/ml 30 salbutamol inhaler 12/27/201614 Hydrocortisone 100mg inj 31 Sodium Chloride 0.9% 21 (NS)

Results- Availability of Medicines 12/27/2016 22

Results- Order Fill Rate cont d Regular insulin X= 9(30%) of the medicines NPH insulin Amoxicillin 125mg/5ml susp. Dextrose 40% amp Phenobarbitone 30mg tabs, Hydrocortisone 100mg inj. Metronidazole 5mg/ml Morphine 10mg/ml inj. ini., TTC eye ointment; N/S 100ML Ceftriaxone 1gm inj., Adrenaline 0.1%/ml, Metoclopramide 5mg/2ml inj Parcetamol 125mg supp. Warfarin 5mg tab Diazepam 5mg/ml amp, X Enalpril 10 mg tabs 4 10 10 11 15.5 24 Average OFR= 62.2% ±35.8) Min OFR= 4% Max OFR= 100 30 38 45.5 52.6 54.4 60 67 75 75 85 100 0 20 40 60 80 100 Order Fill Rate (%) 12/27/2016 23

Results- Order Frequency 6 5 4 3 2 1 0 Order Frequency Ideal Frequency for 6 months 12/27/2016 24

Results- Order Frequency cont d 12/27/2016 25

Results- Stock out Stock out during 6 months (N=30 medicines) Stockout 33% Availible 67% 12/27/2016 26

Results- Stock out---cont d Frequency of stock out during 6 months 128 103 83 55 49 30 23 19 15 2 1 1 1 1 1 1 1 1 3 1 Metformin 500mg tab Morphine 10mg/ml inj. Cimetidine 200mg/2ml Days of stock out during 6 months Manitol 20% Regular insulin Atropine sulphate Plasil 5mg/2ml Hydrocortisone 100mg Adrenaline 0.1%/ml TTC eye ointment 12/27/2016 27

Results- Expire of Medicines 1600 1400 1450 Expired Medicines 1200 1000 1000 800 wastage due to expire 600 400 200 100 0 Adrenaline 0.1%/ml Morphine 10mg/ml TTC eye ointment 12/27/2016 28

Conclusion Pharmaceutical SC performance of TASH was found to be encouraging but not performing as desired level but. It received 62.2% of its medicines request. Long and frequent stock out of medicines was still a challenge. In addition, lack of efficient utilization of pharmaceutical budgets; weak evidence based selection and quantifications of pharmaceuticals were also reported as challenges of the supply chain. 12/27/2016 29

Recommendations Provide training to DSM case team of the hospital pharmacy and managers of the Hospital on how to measure and interpret results of pharmaceutical SCM performance. Also, diversify the involvement of various expertise across the supply chain as appropriate to leverage coordinate Involve stakeholders and partners in the program planning and budgeting of the hospital and mobilize funding for commodity procurement Enter long term agreement with carefully selected private supplier(s) to supply medicines which are frequently stockout or not supplied by PFSA 12/27/2016 30

References Aronovich, Dana, Marie Tien, Ethan Collins, Adriano Sommerlatte, and Linda Allain. 2010. Measuring Supply Chain Performance: Guide to Key Performance Indicators for Public Health Managers. Arlington, Va.: USAID DELIVER PROJECT, Task Order 1. FMOH 2015. Health Sector Transformation Plan (2015/16-2019/20 ). TADEG, H., EJIGU, E., GEREMEW, E. & A., A. 2014. Auditable Pharmaceutical Transactions and Services (APTS): Findings of the Baseline Assessment at Federal, Addis Ababa, and Teaching Hospitals. Arlington, VA: Submitted to the US Agency for International Development by the Systems for Improved Access to Pharmaceuticals and Services (SIAPS) Program. Shewarega, Abiy, Paul Dowling, WelelawNecho, Sami Tewfik, and YaredYiegezu (2015). Ethiopia: National Survey of the Integrated Pharmaceutical Logistics System. Arlington, Va.: USAID DELIVER PROJECT, Task Order 4, and Pharmaceuticals Fund and Supply Agency. 12/27/2016 31

Thank you!!! 12/27/2016 32