Care Coordination Panel Discussion JANSSEN CONNECT

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Care Coordination Panel Discussion JANSSEN CONNECT Jeremy Mann May 5, 2014 #NatCon14 Disclaimer The content of this presentation is the personal views of the presenter, Jeremy Mann, and does not necessarily represent the views of Janssen Pharmaceuticals, Inc. #NatCon14 1 1

Disclaimer Analytics about the program as of the date noted may not be representative of future analytics or your patients or practice. Please consider appropriate use of JANSSEN CONNECT information and assistance in light of your practice and individual patients clinical needs and applicable payer requirements. Information and assistance (e.g., information regarding access and reimbursement, the inpatient/outpatient appointment gap, medication shipment, additional Injection Center options, and follow-through of HCP-directed treatment plan) are provided by United BioSource Corporation ( UBC ), under contract for Janssen Pharmaceuticals, Inc. ( JPI ). A Patient Enrollment Form ( PEF ), with sections completed for requested information regarding assistance, must be submitted to UBC by the healthcare professional ( HCP ) in order to activate any JANSSEN CONNECT assistance. No other forms for request for access to JANSSEN CONNECT will be accepted. Assistance cannot be directly requested by the patient. JANSSEN CONNECT is not available to patients participating in a Patient Assistance Program ( PAP ). The availability of information and assistance may vary based on geography. UBC provides information to healthcare professionals ( HCPs ) regarding whether the treatment is covered by the applicable third-party payer, based on the payer s coverage guidelines and the patient information provided by the HCP. This information and assistance are made available as a convenience to patients, and there is no requirement that patients or HCPs use any JPI or other Johnson & Johnson product in exchange for this information or assistance. JPI assumes no responsibility for and does not guarantee the quality, scope, or availability of the information and assistance provided (e.g., information regarding access and reimbursement, the inpatient/outpatient appointment gap, medication shipment, additional Injection Center options, and follow-through of HCP-directed treatment plan). UBC, not JPI, is responsible for the information and assistance it provides under this program. Each HCP and patient is responsible for verifying or confirming any information provided by UBC or JPI. All claims and other submissions to payers should be in compliance with all applicable requirements. #NatCon14 2 Care Coordination Is the deliberate organization of patient care activities between two or more participants involved in a patient s care to facilitate the appropriate delivery of healthcare services. 1 Reference: 1. McDonald KM, Sundaram V, Bravata DM, et al. Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies, Volume 7 Care Coordination. Rockville, MD: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services; June 2007. #NatCon14 3 2

Janssen Connect does not directly provide care coordination. The Janssen Connect program supports patients by supporting healthcare professional initiatives in care coordination. Janssen Connect offers comprehensive information and assistance to help patients stay on their Janssen long-acting injectable atypical antipsychotic after a healthcare professional has determined it to be the most clinically appropriate treatment option to prescribe. #NatCon14 4 The Need for JANSSEN CONNECT : Gaps in Mental Health Treatment in America Reduced number of state psychiatric beds due to decades of cuts in state and federal mental healthcare funding 1 According to a retrospective longitudinal cohort analysis, 41% of patients received no psychiatric follow-up 1 month after hospital discharge 2 If we are going to help support care coordination, more needs to be done to help patients in taking their healthcare professional-ordered medication. References: 1. The National Alliance on Mental Illness. State Mental Health Cuts: A National Crisis. Chicago; 2011. 2. Olfson M, Marcus SC, Doshi JA. Continuity of care after inpatient discharge of patients with schizophrenia in the Medicaid program: a retrospective longitudinal cohort analysis. J Clin Psychiatry. 2010;71:831-838. #NatCon14 5 3

Patient Barriers* & Treatment Challenges Patients may face healthcare system-related challenges after a long-acting injectable antipsychotic is prescribed: Access and reimbursement understanding The inpatient/outpatient appointment gap Ensuring product is on hand Additional injection center options Follow-through of healthcare professional-directed treatment plan *Derived from market research. #NatCon14 6 Information and Assistance to Help Patients AIDING access and reimbursement understanding Research about your patients Janssen long-acting therapy coverage status #NatCon14 7 4

Information and Assistance to Help Patients BRIDGING the inpatient/outpatient appointment gap Information and assistance to help transition between care settings #NatCon14 8 Information and Assistance to Help Patients COORDINATING medication shipment Assistance coordinating shipment of patient medication to physician offices #NatCon14 9 5

Information and Assistance to Help Patients DETERMINING additional injection center options Patients can receive healthcare professional-ordered injections at a location that may be more conveniently located for them #NatCon14 10 Information and Assistance to Help Patients ENCOURAGING follow-through of a healthcare professional-directed treatment plan Ongoing communication to patients and healthcare professionals regarding treatment follow-through #NatCon14 11 6

#NatCon14 12 Key Facts 16,000+ patients received information and assistance since 2011 1 ~150 patients per week requesting information and assistance 1 Over 2,700+ healthcare professionals 1 and 30,000+ injections administered 1 85% of JANSSEN CONNECT patients returned to an injection center after their first injection 1,2 92% of answered JANSSEN CONNECT reminder calls resulted in an injection 1,3 More than 60% of patients received a successful injection post-discharge as ordered by their healthcare professional 4 This percentage represents hospitalized patients who scheduled a JANSSEN CONNECT Injection Center appointment who went on to receive a successful injection as ordered by their healthcare professional once they left the hospital. Successful injection indicates that the patient attended an appointment to receive his or her healthcare professional-ordered injection and does not refer to clinical outcome. References: 1. Data derived from monthly analytics from JANSSEN CONNECT program. As of 3/31/14. 2. Number of patients who received more than one injection/number of patients who received injections. (2355/2764)*100%=85.20%. 3. Number of answered reminder calls resulting in an injection/number of answered reminder calls (12588/13593)*100%=92.61%. 4. Number of patients with inpatient facility on PEF who scheduled and completed an injection center appointment/number of patients with inpatient facility on PEF who scheduled an injection center appointment (367/530 = 69.25%). As of 04/14. #NatCon14 13 7

2014 Expansion In 2014, JANSSEN CONNECT has expanded nationally: 21 states with full JANSSEN CONNECT model All states with some level of JANSSEN CONNECT information and assistance #NatCon14 14 In Summary The JANSSEN CONNECT program supports patients by supporting healthcare professional initiatives in care coordination: Addresses gaps in mental health treatment in America Focuses on healthcare system-related challenges after a Janssen long-acting injectable antipsychotic is prescribed Offers comprehensive information and assistance to help patients stay on their Janssen long-acting injectable atypical antipsychotic after a healthcare professional has determined it to be the most clinically appropriate treatment option Since 2011, JANSSEN CONNECT has provided information and assistance to 16,000+ patients 1 at the direction of 2,700+ healthcare professionals 1 Administered 30,000+ injections 1 with 85% of patients 2 returning after their first injection In 2014, JANSSEN CONNECT has expanded nationally to bring some level of information and assistance to all states Many unmet needs remain in care coordination for patients. Janssen Connect is one program that can support patients by supporting healthcare professional initiatives in care coordination. References: 1. Data derived from monthly analytics from JANSSEN CONNECT program. As of 3/31/14. 2. Number of patients who received more than one injection/number of patients who received injections. (2355/2764)*100%=85.20%. #NatCon14 15 8