Training Courses on BioPAT MFCS/win 3.0 and DCU 2012

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Training Courses on BioPAT MFCS/win 3.0 and DCU 2012 turning science into solutions

Basic Course BioPAT MFCS/win 3.0 User Training Basic Course BioPAT MFCS/win 3.0 User Training This training is primarily directed towards persons starting with a new BioPAT MFCS/win system or using BioPAT MFCS/win for their daily work. The target of the training is to convey handling with the Batch-Management, Sample-Management, Plots and creation of fermentation documentation. Furthermore training for creation of calculations, profiles and using of recipes will be provided. The participants will have notebooks for hands on training. Topics included: Introduction into SCADA-System BioPAT MFCS/win Shell, Service Control Program Data storing and Batch Management Process Visualization with Operator Service Program Off-line Data Management Evaluation by Plotting Reporting of Batches and Data export Configuration of Variables, Controllers and Calculations Update Configuration and Backup Copy Using S88 Recipes Help-Documentation Course duration 3 days 27 29 March 2012 (German) 26 28 June 2012 (English) 25 27 September 2012 (German) 27 29 November 2012 (English) 1800 plus VAT Maximum of 8 trainees per training

Advanced Course BioPAT MFCS/win 3.0 Manager Training This training is primarily directed towards administrators and experienced users of existing BioPAT MFCS/win systems. The focus of this advanced training is on extended functionality of the software, e. g. creation of event dependent processes by using the S88 recipe approach. Furthermore comprehensive configuration of the system including integration into network environments is provided. The participants will have notebooks for hands on training. Topics included: Overview about BioPAT MFCS/win and its basic functions (Operator Service Program, Data Management, Configuration options) Configuration of Process Units and Control Units PID Control and Applications User Management, 21 CFR Part 11 and Audit Trail Configuration Reports Update Configuration and Backup Copy Maintenance, System Recovery and System Utilities Processes automation with S88 Recipes Installation and Uninstallation of MFCS/win Server Workstation MFCS/win Network Structure and Settings Security Settings Help-Documentation Advanced Course BioPAT MFCS/win 3.0 Manager Training Course duration: 4 days 16 19 April 2012 (German) 22 25 October 2012 (English) 2600 plus VAT Maximum of 6 trainees per training

Advanced Course BioPAT MFCS/win 3.0 Application Training Advanced Course BioPAT MFCS/win 3.0 Application Training This advanced training is primarily directed towards power users who want to create own control and feeding strategies inside BioPAT MFCS/win with recipes and calculations. The target of the training is focused on extended and individualized functionality of BioPAT MFCS/win, e. g. creation of event dependent processes by using the S88 recipe together with complex calculations in BioPAT MFCS/win. Topics included: Integration, Differentiation MIN, MAX Determination Moving Average, Timers If then Else Structures OUR, CER, RQ Calculation Exponential Feed PID Controllers and MFCS PID Control po 2 Cascade Control (DO Control) PD Gravimetric Flow Control Fedbatch Fermentation with Gravimetric Flow Controllers Continuous Fermentation with Gravimetric Flow Controllers DO-Stat ph-stat k L a Determination of k L a Course duration: 3 days 12 14 June 2012 (German) 6 8 November 2012 (English) 2600 plus VAT Maximum of 4 trainees per training

Basic Course MFCS/win 3.0 Crossflow This training is primarily directed towards persons starting with a new MFCS/win system or using MFCS/win for their daily work with Crossflow systems. The target of the training is to convey handling with the Batch-Management, Sample-Management, Plots and creation of filtration documentation. Furthermore training for creation of calculations, profiles and using of recipes will be provided. For practical exercises the participants will have training notebooks for direct use. Topics included: Crossflow filtration, filtration parameters Transmembrane pressure, Reynolds number, yield Introduction into SCADA-System MFCS/win Shell, Service Control Program Data storing and batch management Process visualization with Operator Service Program Off-line data management Evaluation by plotting Reporting of batches and data export Configuration of variables, controllers and calculations DCU sequences for filtration processes Configuration of equipment phases Update configuration und backup copy Automatization of filtration processes with S88 recipes Basic Course MFCS/win 3.0 Crossflow Course duration: 3 days 3 5 July 2012 (German) 1800 plus VAT Maximum of 8 participants per training

Basic Course DCU User Training Basic Course DCU User Training This training is primarily directed towards persons starting with a new DCU fermenter system or using DCU fermenter systems for their daily work. The target of the training is to convey handling with the Main-Operation, Calibration-Operation, Controller-Operation and other System-Operation. The participants will have notebooks for hands on training and also will have training with fermenter systems. Topics included: Start-Menu "Main Calibration (probes, flow, balances) Control Loops Parametrisation of Control loops Setpoint Profiles Gravimetric Dosing po 2 Cascade Control po 2 -Gasmix Controller, po 2 -Gasflow Ratio Controller, Oxygen Enrichment Phases (Sequences) Alarms User Management Trend Display Logbook Functionality System Management (Network, Manual Operation) Course duration: 2 days on demand 1400 plus VAT Maximum of 8 trainees per training

Basic Course ICE (Integrated Configuration Environment) This training is primarily directed towards power users who want to update and modify own configurations or to create own configurations. With part 1 the target of the training is to convey handling with updating on site and modifications for project installation. Part 2 and 3 trains the creation of new functions for system depending configurations. The participants will have notebooks for hands on training. Please note that we will provide separate trainings für DCU3 or DCU4 respectively. Part 1: Basics Update & Modification Overview of the System Firmware and Configuration Update Program and Database Handling Easy Work An Easy Example Modification for a Project Part 2: Advanced Functionality I Functional Specification I/O Definition Function Blocks Visualization Part 3: Advanced Functionality II Phases (Basic Sequences) Documentation Password System Basic Application Basic Course ICE Course duration: 3 days on demand 1800 plus VAT Maximum of 8 trainees per training

Registration Form Fax +49.551.308.1293 Basic Course MFCS/win 3.0 User Training Advanced Course MFCS/win 3.0 Manager Training Advanced Course MFCS/win 3.0 Application Training Basic Course MFCS/win 3.0 Crossflow Basic Course DCU User Training Basic Course ICE Secure yourself the new EXPAND Training and Seminar Catalog 2012! Please send me a copy of the EXPAND Training and Seminar Catalog 2012. Name First Name Title Company Department Company Address Phone Fax E-mail Hotel Accommodation Arrival Date Departure Date Non-smoking room preferred Date Signature

Organization and Information Services The participants will have notebooks for hands on training. Documents, refreshments and daily lunch included. Venue Sartorius College Otto-Brenner-Str. 37079 Goettingen Hotel Accommodation On request, we will be happy to reserve your hotel accommodations. Transfer All courses start at 9 am. Transfer to training-site and back to the preferred hotel is included. Our shuttle service from the hotel starts at 8:45 am. Contact Dr. Claudia Goldmann Training Center Sartorius Stedim Biotech GmbH 37079 Goettingen, Germany Phone +49.551.308.1234 Fax +49.551.308.1293 claudia.goldmann@sartorius-stedim.com Cancellations must be in writing and received 20 working days prior to training courses and workshops. If a registered person cannot attend a course the full registration fee is due and payable, they may appoint a substitute to attend.

Sartorius Stedim Biotech GmbH August-Spindler-Strasse 11 37079 Goettingen, Allemagne Tél. +49.551.308.0 Fax +49.551.308.3289 www.sartorius-stedim.com Specifications subject to change without notice. Printed in Germany on paper that has been bleached without any use of chlorine. W Publication No.: ST-1009-e11103 Order No.: 85032-535-87 Ver. 10 2011