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Grant Application Package Opportunity Title: Offering Agency: CFDA Number: CFDA Description: Opportunity Number: Competition ID: Opportunity Open Date: Opportunity Close Date: Agency Contact: Methodology and Measurement in the National Institutes of Health PAR-16-261 FORMS-D Behavioral and Socia 09/16/2016 09/07/2019 era Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ This opportunity is only open to organizations, applicants who are submitting grant applications on behalf of a company, state, local or tribal government, academia, or other type of organization. Application Filing Name: PI LastName Title of Proposal Select Forms to Complete Mandatory SF424 (R & R) PHS 398 Cover Page Supplement Research And Related Other Project Information Project/Performance Site Location(s) Research and Related Senior/Key Person Profile (Expanded) PHS 398 Research Plan Optional Research & Related Budget R& RSubaward Budget Attachment(s) Form 5 YR 30 ATT PHS 398 Modular Budget PHS 398 Inclusion Enrollment Report PHS Assignment Request Form Instructions Show Instructions >> This electronic grants application is intended to be used to apply for the specific Federal funding opportunity referenced here. If the Federal funding opportunity listed is not the opportunity for which you want to apply, close this application package by clicking on the "Cancel" button at the top of this screen. You will then need to locate the correct Federal funding opportunity, download its application and then apply.

APPLICATION FOR FEDERAL ASSISTANCE SF 424 (R&R) 3. DATE RECEIVED BY STATE State Application Identifier OMB Number: 4040-0001 Expiration Date: 6/30/2016 1. TYPE OF SUBMISSION 4. a. Federal Identifier Pre-application Application Changed/Corrected Application b. Agency Routing Identifier 2. DATE SUBMITTED Applicant Identifier c. Previous Grants.gov Tracking ID 5. APPLICANT INFORMATION Organizational DUNS: Legal Name: Department: University of Louisiana at Lafayette Division: 799451273 Street1: 104 University Circle Ste. 338 City: Lafayette County / Parish: State: Country: USA: UNITED STATES ZIP / Postal Code: 70503-2014 Person to be contacted on matters involving this application Prefix: Mrs. First Name: Abby Last Name: Guillory Middle Name: Suffix: Position/Title: Associate Director, ORSP Street1: 104 University Circle Ste. 338 City: Lafayette State: Country: Phone Number: County / Parish: USA: UNITED STATES ZIP / Postal Code: 70503-2014 3374825811 Fax Number: 3374825102 Email: orsp@louisiana.edu 6. EMPLOYER IDENTIFICATION (EIN) or (TIN): 7. TYPE OF APPLICANT: Other (Specify): 726000820 H: Public/State Controlled Institution of Higher Education Small Business Organization Type Women Owned Socially and Economically Disadvantaged 8. TYPE OF APPLICATION: New Resubmission Renewal Continuation Revision If Revision, mark appropriate box(es). A. Increase Award B. Decrease Award C. Increase Duration D. Decrease Duration E. Other (specify): Is this application being submitted to other agencies? What other Agencies? 9. NAME OF FEDERAL AGENCY: National Institutes of Health 10. CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBER: TITLE: 11. DESCRIPTIVE TITLE OF APPLICANT'S PROJECT: This is the title of your proposal. 12. PROPOSED PROJECT: Start Date Ending Date 08/01/2016 07/31/2021 LA-003 13. CONGRESSIONAL DISTRICT OF APPLICANT

SF 424 (R&R) APPLICATION FOR FEDERAL ASSISTANCE Page 2 14. PROJECT DIRECTOR/PRINCIPAL INVESTIGATOR CONTACT INFORMATION Prefix: Dr. First Name: PI First Name Last Name: PI Last Name Position/Title: Organization Name: Department: University of Louisiana at Lafayette Division: Street1: City: 104 University Circle Ste. 338 Lafayette County / Parish: State: Country: Phone Number: Email: 15. ESTIMATED PROJECT FUNDING a. Total Federal Funds Requested b. Total n-federal Funds c. Total Federal & n-federal Funds d. Estimated Program Income 17. By signing this application, I certify (1) to the statements contained in the list of certifications* and (2) that the statements herein are true, complete and accurate to the best of my knowledge. I also provide the required assurances * and agree to comply with any resulting terms if I accept an award. I am aware that any false, fictitious. or fraudulent statements or claims may subject me to criminal, civil, or administrative penalties. (U.S. Code, Title 18, Section 1001) I agree *The list of certifications and assurances, or an Internet site where you may obtain this list, is contained in the announcement or agency specific instructions. 18. SFLLL (Disclosure of Lobbying Activities) or other Explanatory Documentation 19. Authorized Representative Middle Name: Suffix: USA: UNITED STATES ZIP / Postal Code: 70503-2014 PI Phone Number Fax Number: PI Fax Number PI email@louisiana.edu 133,006.00 0.00 0.00 0.00 16. IS APPLICATION SUBJECT TO REVIEW BY STATE EXECUTIVE ORDER 12372 PROCESS? a. YES THIS PREAPPLICATION/APPLICATION WAS MADE AVAILABLE TO THE STATE EXECUTIVE ORDER 12372 PROCESS FOR REVIEW ON: DATE: b. NO PROGRAM IS NOT COVERED BY E.O. 12372; OR PROGRAM HAS NOT BEEN SELECTED BY STATE FOR REVIEW Prefix: Dr. First Name: Ramesh Last Name: Kolluru Position/Title: Vice President for Research Organization: University of Louisiana at Lafayette Department: Division: Middle Name: Suffix: Street1: 104 University Cirlce Ste. 338 City: Lafayette County / Parish: State: Country: USA: UNITED STATES ZIP / Postal Code: 70503-2014 Phone Number: 3374825811 Fax Number: 3374825102 Email: research@louisiana.edu Signature of Authorized Representative Date Signed Completed on submission to Grants.gov Completed on submission to Grants.gov 20. Pre-application 21. Cover Letter Attachment

PHS 398 Cover Page Supplement OMB Number: 0925-0001 Expiration Date: 10/31/2018 1. Human Subjects Section Clinical Trial? *Agency-Defined Phase III Clinical Trial? 2. Vertebrate Animals Section Are vertebrate animals euthanized? If "" to euthanasia Is method consistent with American Veterinary Medical Association (AVMA) guidelines? If "" to AVMA guidelines, describe method and provide scientific justification 3. *Program Income Section *Is program income anticipated during the periods for which the grant support is requested? If you checked "yes" above (indicating that program income is anticipated), then use the format below to reflect the amount and source(s). Otherwise, leave this section blank. *Budget Period *Anticipated Amount ($) *Source(s) 4. Human Embryonic Stem Cells Section *Does the proposed project involve human embryonic stem cells? If the proposed project involves human embryonic stem cells, list below the registration number of the specific cell line(s) from the following list: http://stemcells.nih.gov/research/registry/. Or, if a specific stem cell line cannot be referenced at this time, please check the box indicating that one from the registry will be used: Specific stem cell line cannot be referenced at this time. One from the registry will be used. Cell Line(s) (Example: 0004):

PHS 398 Cover Page Supplement 5. Inventions and Patents Section (RENEWAL) *Inventions and Patents: If "" then answer the following: *Previously Reported: 6. Change of Investigator / Change of Institution Section Change of Project Director / Principal Investigator Name of former Project Director/Principal Investigator: Prefix: *First Name: Middle Name: *Last Name: Suffix: Change of Grantee Institution *Name of former institution:

RESEARCH & RELATED Other Project Information OMB Number: 4040-0001 Expiration Date: 6/30/2016 1. Are Human Subjects Involved? 1.a. If YES to Human Subjects Is the Project Exempt from Federal regulations? If yes, check appropriate exemption number. If no, is the IRB review Pending? IRB Approval Date: 1 2 3 4 5 6 Human Subject Assurance Number: 2. Are Vertebrate Animals Used? 2.a. If YES to Vertebrate Animals Is the IACUC review Pending? IACUC Approval Date: Animal Welfare Assurance Number: 3. Is proprietary/privileged information included in the application? 4.a. Does this Project Have an Actual or Potential Impact - positive or negative - on the environment? 4.b. If yes, please explain: 4.c. If this project has an actual or potential impact on the environment, has an exemption been authorized or an environmental assessment (EA) or environmental impact statement (EIS) been performed? 4.d. If yes, please explain: 5. Is the research performance site designated, or eligible to be designated, as a historic place? 5.a. If yes, please explain: 6. Does this project involve activities outside of the United States or partnerships with international collaborators? 6.a. If yes, identify countries: 6.b. Optional Explanation: 7. Project Summary/Abstract ProjectAbstract.pdf 8. Project Narrative ProjectNarrative.pdf 9. Bibliography & References Cited 10. Facilities & Other Resources 11. Equipment 12. Other Attachments s s s

Project/Performance Site Location(s) OMB Number: 4040-0010 Expiration Date: 9/30/2016 Project/Performance Site Primary Location I am submitting an application as an individual, and not on behalf of a company, state, local or tribal government, academia, or other type of organization. Organization Name: DUNS Number: University of Louisiana at Lafayette 7994512730000 * Street1: Address of Project Site * City: City of Project Site County: * State: * Country: USA: UNITED STATES * ZIP / Postal Code: Zip of Project Site * Project/ Performance Site Congressional District: LA-003 Project/Performance Site Location Organization Name: 1 I am submitting an application as an individual, and not on behalf of a company, state, local or tribal government, academia, or other type of organization. DUNS Number: * Street1: * City: County: * State: * Country: USA: UNITED STATES * ZIP / Postal Code: * Project/ Performance Site Congressional District: Additional Location(s)

RESEARCH & RELATED Senior/Key Person Profile (Expanded) OMB Number: 4040-0001 Expiration Date: 6/30/2016 PROFILE - Project Director/Principal Investigator Prefix: Dr. * First Name: PI First Name Middle Name: * Last Name: PI Last Name Suffix: Position/Title: Department: Organization Name: University of Louisiana at Lafayette Division: * Street1: * City: 104 University Circle Ste. 338 Lafayette County/ Parish: * State: * Country: USA: UNITED STATES * Zip / Postal Code: 70503-2014 * Phone Number: PI Phone Number Fax Number: PI Fax Number * E-Mail: PI email@louisiana.edu Credential, e.g., agency login: PI era Commons username * Project Role: PD/PI Other Project Role Category: Degree Type: Degree Year: *Attach Biographical Sketch Attach Current & Pending Support PIBiosketch.pdf PROFILE - Senior/Key Person 1 Prefix: Dr. * First Name: Co-PI First Name Middle Name: * Last Name: Co-PI Last Name Suffix: Position/Title: Department: Organization Name: Co-PI Organization Name Division: * Street1: Co-PI Street Address * City: Co-PI City County/ Parish: * State: * Country: USA: UNITED STATES * Zip / Postal Code: Co-PI Zip Code + 4 * Phone Number: Co-PI Phone Number Fax Number: * E-Mail: Co-PI email@organization.com Credential, e.g., agency login: Co-PI era Commons username * Project Role: Co-PD/PI Other Project Role Category: Degree Type: Degree Year: Attach Biographical Sketch Attach Current & Pending Support CoPIBiosketch.pdf Delete Entry Next Person To ensure proper performance of this form; after adding 20 additional Senior/ Key Persons; please save your application, close the Adobe Reader, and reopen it.

PHS 398 Research Plan OMB Number: 0925-0001 Expiration Date: 10/31/2018 Introduction 1. Introduction to Application (Resubmission and Revision) Research Plan Section 2. Specific Aims 3. *Research Strategy 4. Progress Report Publication List ResearchStrategy.pdf Human Subjects Section 5. Protection of Human Subjects 6. Data Safety Monitoring Plan 7. Inclusion of Women and Minorities 8. Inclusion of Children Other Research Plan Section 9. Vertebrate Animals 10. Select Agent Research 11. Multiple PD/PI Leadership Plan 12. Consortium/Contractual Arrangements 13. Letters of Support 14. Resource Sharing Plan(s) 15. Authentication of Key Biological and/or Chemical Resources Appendix 16. Appendix s s s

RESEARCH & RELATED BUDGET - Budget Period 1 OMB Number: 4040-0001 Expiration Date: 6/30/2016 ORGANIZATIONAL DUNS: 7994512730000 Enter name of Organization: University of Louisiana at Lafayette Budget Type: Project Subaward/Consortium Budget Period: 1 Start Date: 08/01/2016 End Date: 07/31/2017 A. Senior/Key Person Prefix First Middle Last Suffix Base Salary ($) Dr. PI First Name Months Cal. Acad. Sum. Requested Salary ($) Fringe Benefits ($) Funds Requested ($) PI Last Name 58,000.00 2.00 12,889.00 6,167.00 19,056.00 Project Role: PD/PI Dr. Co-PI First Name Co-PI Last Name 56,000.00 2.00 12,444.00 5,954.00 18,398.00 Project Role: Co-PI/PD Additional Senior Key Persons: Total Funds requested for all Senior Key Persons in the attached file Total Senior/Key Person 37,454.00 B. Other Personnel Number of Personnel Project Role Cal. Months Acad. Sum. Requested Salary ($) Fringe Benefits ($) Funds Requested ($) Post Doctoral Associates 2 Graduate Students Undergraduate Students Secretarial/Clerical 9.00 3.00 28,800.00 551.00 29,351.00 2 Total Number Other Personnel Total Other Personnel 29,351.00 Total Salary, Wages and Fringe Benefits (A+B) 66,805.00

C. Equipment Description List items and dollar amount for each item exceeding $5,000 Equipment item Funds Requested ($) Additional Equipment: Total funds requested for all equipment listed in the attached file Total Equipment D. Travel 1. Domestic Travel Costs ( Incl. Canada, Mexico and U.S. Possessions) 2. Foreign Travel Costs Funds Requested ($) 2,000.00 4,000.00 Total Travel Cost 6,000.00 E. Participant/Trainee Support Costs 1. Tuition/Fees/Health Insurance 2. Stipends 3. Travel 4. Subsistence 5. Other Funds Requested ($) Number of Participants/Trainees Total Participant/Trainee Support Costs

F. Other Direct Costs Funds Requested ($) 1. Materials and Supplies 6,000.00 2. Publication Costs 1,500.00 3. Consultant Services 4. ADP/Computer Services 5. Subawards/Consortium/Contractual Costs 6. Equipment or Facility Rental/User Fees 7. Alterations and Renovations 8. 9. 10. Tuition 16,564.00 Total Other Direct Costs 24,064.00 G. Direct Costs Funds Requested ($) Total Direct Costs (A thru F) 96,869.00 H. Indirect Costs Indirect Cost Type Indirect Cost Rate (%) Indirect Cost Base ($) Funds Requested ($) Modified Total Direct Costs 45.00 80,305.00 36,137.00 Total Indirect Costs 36,137.00 Cognizant Federal Agency (Agency Name, POC Name, and POC Phone Number) DHHS, Ernest Kinneer, 214-767-3529 I. Total Direct and Indirect Costs Funds Requested ($) Total Direct and Indirect Institutional Costs (G + H) 133,006.00 J. Fee Funds Requested ($) K. Budget Justification (Only attach one file.) BudgetJustification.pdf

RESEARCH & RELATED BUDGET - Cumulative Budget Section A, Senior/Key Person Section B, Other Personnel Total Number Other Personnel Total Salary, Wages and Fringe Benefits (A+B) Section C, Equipment Section D, Travel 1. Domestic 2. Foreign Section E, Participant/Trainee Support Costs 1. Tuition/Fees/Health Insurance 2. Stipends 3. Travel 4. Subsistence 5. Other 6. Number of Participants/Trainees Section F, Other Direct Costs 1. Materials and Supplies 2. Publication Costs 3. Consultant Services 4. ADP/Computer Services 5. Subawards/Consortium/Contractual Costs 6. Equipment or Facility Rental/User Fees 7. Alterations and Renovations 8. Other 1 9. Other 2 10. Other 3 Section G, Direct Costs (A thru F) Section H, Indirect Costs Section I, Total Direct and Indirect Costs (G + H) Section J, Fee Totals ($) 2 2,000.00 4,000.00 6,000.00 1,500.00 16,564.00 37,454.00 29,351.00 66,805.00 6,000.00 24,064.00 96,869.00 36,137.00 133,006.00