Kaiser Permanente Research A Very Brief Introduction Michael Horberg, MD MAS FACP FIDSA Executive Director Research, Community Benefit, and Medicaid Strategy; Mid- Atlantic Permanente Medical Group
Kaiser Permanente (KP) Our Mission: To provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. Integrated delivery system (hospitals, clinicians, pharmacies, lab and x-ray, etc.) and financing scheme Operates like a mini- national health system Single funding stream with global budget Accountable for total health of a population KP defines the integrated model of health care financing and delivery through its unique partnership among three entities: contractual and exclusive Our Hospitals or Hospital Partners Permanente Medical Groups Health Plan Members Our Patients Kaiser Foundation Health Plan Non profit Prepaid Integrated 7 regions Colorado Hawaii Georgia Mid Atlantic (DMV) Northern California Northwest (OR, WA) Southern California
KP Research Was Part of Our Learning Health Care Organization From the Beginning Early research at KP leveraged Morrie Collen s Multiphasic Health Screening Exam and the storage of data for clinical care and research Built on a systems engineering model, research and clinical care were tightly integrated, as was care delivery Education and coverage 3 Research Care Delivery & Coverage
>140 Investigators Come From a Wide Variety of Disciplines In 2012, External Sources Constituted 75% of Kaiser Permanente Research Funding ($>200 Million)
KP Research Has Advanced Knowledge in Multiple Clinical Areas Just a Few Examples Immunizations Serve as primary data source & key analytic team for the CDC s national vaccine safety surveillance system Conducted large-scale effectiveness studies of new childhood vaccines Colorectal Cancer (CRC) National CRC screening guidelines were shaped by KP research Research found that almost half of CRC deaths could have been prevented through appropriate screening Contributed to implementing a robust CRC screening program that has eliminated CRC mortality disparities Cardiovascular/Stroke Implemented the KP ALL protocol effectively in community health centers Developed effective methods to increase adherence to cardiovascular medications Determined that relative risk for myocardial infarction is declining among HIV+ patients Genomics Designed high-throughput genotyping arrays optimized for East Asian, African American, and Latino race/ethnicity Developed framework for evaluating translation of genomic tests to practice Identified under-utilization of Lynch Syndrome testing 5
KP Strives to Embody A Learning Health Care System Research & Analytics Information rich, member focused enterprises Data Evidence is continually refined as a byproduct of assessing ourselves 21 st Century Health Care Information and evidence enable effective design and delivery of care Point of Interaction Tools Actionable information available to decision makers just in time Research & Analytics
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Kaiser Permanente Publications Continue to Increase Annually Number of publications Areas of Focus To Name a Few Disease Epidemiology Prevention, Diagnosis & Treatment of Major Chronic Diseases Cardiovascular Diabetes Cancer HIV/AIDS Mental Health Substance Abuse Safety of Health Care Interventions Vaccines Medications Devices Health Services Quality Improvement/Measurement
Range of Design and Study Methods Used Surveillance Predictive Analytics Epidemiologic and Observational Studies retrospective and longitudinal Intervention Studies Pharmaceutical, device, process trials Genomics Implementation Science
Mid-Atlantic Permanente Research Institute Research enterprise of MAPMG with strong support from KPMAS At present, 4+ research scientists, 8+ clinical research nurses Plus full support staff including: Programmers/analysts Administrative staff Project Managers, Research Associates, etc Grants and contracts administration Legal and Accounting support Areas of emphasis (but not limited to!): Clinical Trials (especially Oncology, Hepatitis, CVD, Neurology) Health Equity (disparities) Health Informatics Health Services, including economics and comparative health systems HIV/AIDS and Viral Hepatitis Oncology Cardiovascular and Metabolic (Diabetes) Neurology September 23, 2015 10 Our mission is to advance medical knowledge and improve the quality of care and health of our patients and communities we serve by conducting innovative scientific and clinical research.
Development of KPMAS Data Warehouse: Example in Effort; Each Region has Own Data Warehouse