Innovations in Cardiovascular Care

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C A R D I O L O G Y P H I L A D E L P H I A 2016 Innovations in Cardiovascular Care with Illustrative Live Patient Presentations for Cardiologists, Primary Care Physicians, Advanced Care Practitioners, and Nurses Sheraton Philadelphia Downtown Hotel 201 North 17th Street 19103 FORMERLY CARDIOLOGY UPDATE In Conjunction with PROGRAM DIRECTORS Terry D. Friedman, MD John J. Ross, Jr., RDCS, RVS, RCS Harvey L. Waxman, MD Penn Medicine,

COURSE OVERVIEW AND TARGET AUDIENCE This conference is designed for cardiologists, primary care physicians, advanced nurse practitioners, and nurses who have a special interest in cardiology. It will focus on practical and clinical issues faced on a daily basis by the health care professional. There will be a combination of case presentations and didactic lectures, which will be used to provide an academically sound and clinically relevant cardiology review. Presentations will be provided by nationally recognized experts in their fields. The guest faculty will be joined by members from The University of Pennsylvania School of Medicine. The program will include live clinical case presentations throughout the day as well as real time echocardiography performed on multiple patients. Additionally, there will be a detailed discussion of each case. LEARNING OBJECTIVES Upon completion of the activity, participants should be able to: Review the expanding indication for transaortic valve replacement surgery (TAVR) Discuss use of cardiac pacemakers including the leadless device Review the newer medications used for heart failure Explain the appropriate cardiac screening options for athletes Review the acceptable hemoglobin level recommended for patients with cardiac disease Discuss the appropriate treatment for abdominal aortic aneurysm: endovascular vs surgery Describe the current management of hyperlipidemia including the use of PCSK9 inhibitors Manage stroke prevention in patients with atrial fibrillation: drugs and left atrial closure devices Review the current approach to patients with carotid artery disease Discuss surgical options in severe secondary mitral valve regurgitation Review the wearable cardioverter-defibrillator and its role in preventing sudden cardiac death Assess the ways of reducing cardiac complications in patients undergoing major non cardiac surgery Review potential cardiac deleterious effects of long-term endurance exercise Discuss the modern treatments of acute pulmonary embolism HOSTING ORGANIZATIONS Cardiology Philadelphia 2016: Innovations in Cardiovascular Care is hosted by the Philadelphia Heart Institute of and the Heart Institute of Southern New Jersey. ACCREDITATION Physicians: The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Nurses: Penn Medicine Nursing is an approved provider of continuing nursing education by the Pennsylvania State Nurses Association, an accredited approver by the American Nurses Credentialing Center s Commission on Accreditation. Approval # 124-3-H-15

DESIGNATION OF CREDIT Physicians: The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 7.75 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurses: The program will award 7.5 contact hours. AAPA: AAPA accepts certificates of participation for educational activities certified for Category I credit from AOACCME, Prescribed credit from AAFP, and AMA PRA Category 1 Credits from organization accredited by ACCME or a recognized state medical society. Certificates and Transcripts: A few days prior to the symposium, pre-registered participants will receive an email containing directions, additional symposium information and a link to the symposium pre-test, a short questionnaire that will be used to gauge participant knowledge. After the symposium has concluded, all participants will receive a follow-up email containing a link to the post-test, symposium evaluation and credit request. Once participants submit the request for credit, the credit can be viewed on a transcript or a certificate can be printed by logging onto www.penncmeonline.com. DISCLOSURES Perelman School of Medicine at the University of Pennsylvania, Office of Continuing Medical Education, adheres to the ACCME Standards for Commercial Support. Faculty disclosure information will be made available in the conference materials and syllabi. Faculty members are also expected to disclose to participants any discussions of off-label and/or investigational uses of pharmaceutical products within their presentations. REGISTRATION FEES The registration fees for Cardiology Philadelphia 2016: Innovations in Cardiovascular Care are $150.00 for physicians or industry and $100.00 for nurses and other healthcare professionals, residents and fellows. Penn Medicine employees, faculty, staff and students will receive a 10% discount. A valid Penn Medicine ID is required to receive the special rate. The registration fee includes attendance to the conference, a course booklet and a link to view the presentations online, continental breakfast, mid-morning and afternoon refreshments, lunch, and post-symposium reception. If you are registering with a credit card, please register online at www.penncmeonline.com, then clicking on CME Activities/Live Events. To pay by check, complete the registration form and mail it in with your check. We cannot accept faxed or mailed registration forms with credit card information. Please see the top of the registration form for mailing information. Please note: mailed registrations can take up to 5-10 business days before they are received. All registrations will be confirmed by email as long as your registration is received no later than September 30, 2016. MEETING LOCATION Cardiology Philadelphia 2016: Innovations in Cardiovascular Care will take place on Saturday, October 15, 2016 at the Sheraton Philadelphia Downtown Hotel, 201 North 17th Street, 19103. The hotel s main number is 215-448-2000. OVERNIGHT RESERVATIONS A block of rooms has been reserved at the Sheraton Philadelphia Downtown Hotel at a special group rate of $209 per night single/ double occupancy. Taxes are 15.5% per room per night and are subject to change. We recommend you make a reservation as soon as possible because there are a limited number of rooms available. Please call the Sheraton Philadelphia Downtown Hotel reservations directly at 215-448-2000 or 1-800-325-3535. Identify yourself as a Cardiology Philadelphia 2016 participant. This room block is available until September 13, 2016 or until the block is full. Parking: The Sheraton Philadelphia Downtown Hotel offers valet parking services ($44 daily rate) and self-parking in their garage ($38 daily rate). An additional parking option is at The Philadelphia Gateway parking garage, which is located one block from the Sheraton at 1540 Vine Street between 15th and 16th street ($7 daily rate). For information on additional overnight accommodations or what to do or see while you re in Philadelphia, please go to www.gophila.com.

COURSE DIRECTORS Terry D. Friedman, MD Medical Director, Penn Cardiology, Cherry Hill John J. Ross, Jr., RDCS, RVS, RCS Director, Out Patient Non Invasive Cardiovascular Network Harvey L. Waxman, MD Chief of Cardiology COURSE FACULTY Anelechi Anyanwu, MD Professor, Cardiothoracic Surgery Mount Sinai Medical Center New York, NY Joshua A. Beckman, MD Director, Section of Vascular Medicine Vanderbilt University Medical Center Nashville, TN Philip J. Devereaux, MD Professor, Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton, Ontario, Canada Benjamin A. D Souza, MD Lee R. Goldberg, MD, MPH Medical Director of Heart Failure and Transplantation Program Hospital of The University of Pennsylvania Douglas S. Jacoby, MD Director, Preventive Care Sameer Khandhar, MD Clinical Assistant Professor of Medicine Paul D. Thompson, MD Director of Cardiology Hartford Hospital Hartford, CT Robert M. Bunting, RDCS, RVS Jeffrey L. Carson, MD Provost-Rutgers Biomedical and Health Sciences Professor of Medicine Rutgers Robert Wood Johnson Medical School New Brunswick, NJ Larry A. Chinitz, MD Professor of Medicine NYU Langone Medical Center New York, NY

P R O G R A M A G E N D A Live Case Presentations Throughout the Day with Live Echocardiograms 7:00 AM Registration and Continental Breakfast 7:45 AM Welcome Remarks/Moderator Terry D. Friedman, MD 8:00 AM Expanding the Indications for TAVR in 2016 and Beyond This presentation will review a surgeon s perspective on the future of TAVR in patients with aortic stenosis Anelechi Anyanwu, MD 8:35 AM The Future of Cardiac Pacing This presentation will review cardiac pacemaker therapy including the use of the leadless pacemaker Larry A. Chinitz, MD 9:10 AM Be Careful What You Wish For New Drugs for the Treatment of Heart Failure This presentation will review the recently introduced medications used in the treatment for heart failure Lee R. Goldberg, MD 9:40 AM Break 9:55 AM Does Mandatory ECG Screening of Athletes Save Lives This presentation will review current guidelines and the literature regarding appropriate cardiac screening for athletes Paul D. Thompson, MD 10:25 AM Blood Transfusion in Anemic Cardiac Patients: How Low Can We Go? This presentation will discuss the level of acceptable hemoglobin in patients with cardiac disease Jeffrey L. Carson, MD 10:55 AM Abdominal Aortic Aneurysm This presentation will review endovascular repair and open surgical repair: What is best for your patient? Joshua A. Beckman, MD 11:25 AM Current Approaches to Lipid Management and the Practical Use of PCSK9 Inhibitors This presentation will review an up-to-date approach of managing patients with lipid abnormalities Douglas S. Jacoby, MD 12:00 PM Lunch 1:00 PM Stroke Prevention for Atrial Fibrillation: Medications and Devices This presentation will discuss the options available to prevent stroke in patients with atrial fibrillation including left atrial closure devices Larry A. Chinitz, MD 1:30 PM Carotid Stent or Carotid Endardarectomy: What is Best for your Patient? This presentation will review the recent literature regarding the approach to the patient with carotid artery disease Joshua A. Beckman, MD 2:10 PM Secondary Mitral Valve Regurgitation: When and How to Intervene This presentation will review one surgeon s approach to secondary mitral valve regurgitation Anelechi Anyanwu, MD 2:40 PM Wearable Cardioverter-Defibrillator This presentation will review the data regarding the use of this device in preventing sudden cardiac death Benjamin D Souza, MD 3:00 PM Break 3:15 PM Cardiac Complications in Patients Undergoing Major Non-Cardiac Surgery The presentation will discuss new concepts in preoperative evaluation and recommendations for detecting postoperative complications Philip J. Devereaux, MD 4:00 PM Are There Deleterious Cardiac Effects from Life Long Endurance Exercise? This presentation will review the long-term cardiac risks of life long exercise Paul D. Thompson, MD 4:30 PM Modern Treatment of Acute Pulmonary Embolism This presentation will review the concept of minor, submassive, and massive pulmonary embolism and there will be discussion of treatments including anticoagulation, thrombolytics, and catheter intervention Sameer Khandhar, MD 5:00 PM Adjournment 5:00 PM Cocktail Reception Services for the Disabled If special arrangements are required for an individual with a disability to attend this meeting, please contact the Office of Continuing Medical Education no later than September 30, 2016 at 215-898-6400. Nondiscrimination Statement The University of Pennsylvania values diversity and seeks talented students, faculty, and staff from diverse backgrounds. The University of Pennsylvania does not discriminate on the basis of race, sex, sexual orientation, gender identity, religion, color, national or ethnic origin, age, disability, or status as a Vietnam Era Veteran or disabled veteran in the administration of educational policies, programs or activities; admissions policies; scholarship and loan awards; athletic, or other University administered programs or employment. Questions or complaints regarding this policy should be directed to Executive Director, Office of Affirmative Action and Equal Opportunity Programs, 3600 Chestnut Street, Sansom Place East Suite 228, Philadelphia PA 19104-6106 or 215-898-6993 (Voice) or 215-898-7803 (TDD). www.upenn.edu/affirm-action.

CARDIOLOGY PHILADELPHIA Innovations in Cardiovascular Care REGISTRATION FORM If you are registering using your credit card, please register online at: www.penncmeonline.com and click on CME Activities/Live Events. Questions? Contact us at: Phone: 215-898-6400 or 215-898-8005 penncme@mail.med.upenn.edu Please note we are unable to accept faxed registration forms. PLEASE PRINT OR TYPE Name (First) (Last) Academic Degree Medical Specialty Affiliation (Hospital, Office, or Company) Address ( Affiliation or Home) City State Zip Phone Fax E-mail Registration Fees (pre-payment is required to be officially registered) $150 for Practicing Physicians $100 for Residents, Fellows, Nurses, and Allied Health Professionals $135 for UPHS Physicians (with valid ID) $90 for UPHS House Staff, Nurses, and Allied Health Professionals (with valid ID) Penn Medical ID # Payment Method If you are paying by credit card, please register online at www.penncmeonline.com and click on CME Activities/Live Events. If you are paying by check, you may mail your completed registration form and check made payable to The Trustees of the University of Pennsylvania/CME to: Conference Coordinator, Perelman School of Medicine at the University of Pennsylvania, Office of Continuing Medical Education 150 Anatomy/Chemistry Building, 3620 Hamilton Walk, 19104-6061 Do not include any credit card information on the registration form or email any credit card information Please Note: Walk-in registrants must bring payment to the program. Seating may be limited for walk-in registrants.

150 Anatomy/Chemistry Building 3620 Hamilton Walk 19104-6061 CARDIOLOGY PHILADELPHIA Innovations in Cardiovascular Care Sheraton Philadelphia Downtown Hotel 201 North 17th Street 19103 FORMERLY CARDIOLOGY UPDATE Non-Profit Org. U.S. Postage P A I D Permit No. 2563 Phila., PA 19104