The University Connection

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The University Connection Partnerships to Leverage SBIR/STTR for Regional Growth Presentation to The National Academies: SBIR/STTR & the Role of State Programs Glendowlyn Thames Director of Small Business Innovation, Connecticut Innovations October 7, 2014

Connecticut Innovations At A Glance Quasi-public organization formed 25 years ago to: Promote innovation and help promising, early-stage, high-tech companies start and grow Create and retain high-quality jobs; build economic value We Invest using private sector principles to achieve a public purpose Provide more than money Fill gaps Leverage capital 2

Stages of Company Development How does CI help? CTNext Entrepreneurial Ecosystem, Networks and Partnerships Grants for technology acceleration Grants for product innovation Grants for STEM internships Loans Venture debt Research and Development Proof of concept Product Development Launch and early customer traction Scaling and adoption Business expansion Bioscience Innovation Fund Regenerative Medicine Research Fund Pre-seed, seed and growth equity funds Angel Investor Tax Credit 3

CI Today June 2014 Stats More than $200 million in assets 520 portfolio companies More than 19,000 jobs (current) Annual Activity Bioscience Commercialization $17 million Equity $25 million $76 million for investments and programs $60 million non-cash assistance Support more than 150 companies and 40 scientists $3 million for angel investor tax credits Bioscience Research $10 million Entrepreneurial Ecosystem $4 million Innovation Grants $4 million Loans $16 million Average Annual Investment 4

Small Business Innovation Growing a vibrant innovation ecosystem that incorporates networks of business support and resources Promote and provide support to Connecticut entrepreneurs and companies through programs and initiatives such as: SBIR/STTR grant support Assessment reports: technology and market Interns: talent access and funding -Technology Talent Bridge Internship Grant Program Grants for innovative manufacturing Small Business Innovation and Diversification Program - $25K grants Making connections matching programs CTNext (Connecticut s entrepreneurial ecosystem) Accelerate company development Improve entrepreneur connections Provide grants for entrepreneur-focused programs i.e. accelerators, co-working space, 10K competitive grants for startups 5

CI Engaging Universities 6

Connecticut s SBIR Program - Overview Started in 2004 Counseled hundreds of companies Hosted two national SBIR/STTR conferences Hosted several regional conferences, workshops and webinars Recent initiatives: Acceleration and Commercialization Program One-on-one outreach to students, faculty and small businesses FAST outreach dedicated consultant to educate minority-owned, womanowned and veteran-owned small businesses Outreach throughout the state including community colleges 7

Engaging Universities - CI Office hours on site began late 2013 at Yale and mid-2014 at UCONN SBIR Acceleration and Commercialization Program/federal leveraging Internship program Reimbursement to attend SBIR conferences Accounting support for proposals Technology Assessment Reports and Market Assessment Reports One-on-one support proposal reviews and strategy sessions Funding to UCONN - Third Bridge Funding to Yale - YEI Innovation Fund Prototype Fund Manufacturing Innovation Fund Bioscience Innovation Fund Angel Tax Credit Program 8

SBIR/STTR University Engagement Office Hours Spend three days per month at UCONN and Yale University In-depth one-on-one overviews, mentoring and proposal strategies Presentations and one-on-one sessions involving university incubators Access to technology assessment and market assessment reports University startups access to interns Workshops, webinars Proposal reviews Strategic Focus: Leverage academic grants that have technologies that are ripe for SBIR/STTR commercialization 9

Technology Transfer Problem Solving Tech Transfer Issues Working with UCONN to solve tech transfer stumbling blocks IP ownership/sharing Facilitating partnerships with small businesses that wish to pursue STTRs Future collaborative sessions with researchers and targeted small businesses Changing university venture model structure New University Venture Model 10

SBIR Acceleration and Commercialization Highlights Since 2012 we have provided more than $2.3 million to SBIR/STTR winners at 57 companies and have leveraged more than $22 million in federal dollars and private investment We have site visits with all of our companies and track quarterly metrics They know and trust us Additional planned outreach: $100,000 including $30K to UCONN and $30K to Yale to host 2-day intense educational workshops focused on DOD and NIH using SBIR consultants. One-on-one support for proposal writing, editing and strategy 11

SBIR Acceleration and Commercialization Success Royalty-Based Agreement Biorasis Biorasis developing a tiny implantable sensor for continuous diabetes monitoring Needed a cash match for a Phase IIB SBIR NSF Royalty-based partner agreement is now a state model 12

Internship Program Providing Student Interns with Real-World Experience Mission is to provide experiential learning to students at small businesses in CT--experience that leads to jobs For the past two years our team has funded 78 grants to companies to hire 145 interns at a total cost of $1 million 22 participating colleges/universities in Connecticut 70% job offer rate as of April 30, 2014 with more in progress 13

UCONN Third Bridge Partnering with UCONN s School of Engineering CI -$575,000 School of Engineering match-$150,000 Grant support for commercially viable student- and faculty-led startups. Six companies funded: 3 bioscience 1 bioinformatics 2 advanced product development 14

UCONN Third Bridge Success Highlight - SmplBiO University, Industry, Government Partnering Originally funded $30k through Third Bridge partnership Spin-off: IP generated from UCONN Bioinformatics software toolkit $150k award from CI Innovation Challenge $150k company match $150k match from industry partner (Fluidigm) Estimate three years to commercialization 15

YEI Innovation Fund Started early 2014 Partnering with Yale s Entrepreneurial Institute (YEI) The Fund has $3 million - $1.25M CI, $1.25 million match from Yale and $500K from First Niagara Bank Matching funds from the School of Engineering as grant support for commercially-viable student- and faculty-led startups. Results: So far 2 out of the 3 investments have received follow on $1M+ investments Isoplexis received a $1.25 Series A round including $300K from CI for a single cell immunoassay device and software that provides in-depth understanding of immune and cancer cell activity. They submitted an SBIR proposal in August. 16

Federal Leveraging - ZetrOZ Federal Leveraging Cornell with NASA Attracted to CT s ecosystem Developed wearable ultrasound device targeting back pain Won SBIR $2.5 million of CI VC funding and leveraged additional $250K to win $250K NASA grant $55K from other CI programs Additional $100K from Dept. of Economic & Community Development $30K grant in progress through SBIR A&C 17

Summary - Still Reaching! We re Still Trying New Things Collaboration is key to success We would like to expand our programs to engage other universities such as Wesleyan University and the University of Hartford We added about a dozen new companies to our SBIR pipeline in FY 2013 At least 1/3 of our SBIR winners collaborate with universities We re always open to new ideas and best practices 18

Questions? Glendowlyn L.H. Thames Director of Small Business Innovation Glendowlyn.Thames@ctinnovations.com direct: 860.257.2332 fax: 860.536.4877 web: ctinnovations.com 865 Brook Street, Rocky Hill, CT 06067 19