South West Chemotherapy Meeting 22 April Notes - draft

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South West Chemotherapy Meeting 22 April 2014 Notes - draft 1 Welcome & Apologies See Appendix 1 2 Terms of reference Next Meeting to have webex or videoconferencing available It was suggested that a GP be asked to be a member. HT to consider this Actions HT Patient Engagement National Chemotherapy Patient Experience Survey to be discussed at next meeting. Decision on Patient engagement to be taken then. Patients may register as a stakeholder with the National Chemotherapy Clinical Reference Group (CRG) Research Oncology Pharmacy Group This Group will meet on same day as Chemotherapy Group Chemotherapy Nurse Group This Group will meet on same day as Chemotherapy Group 3 National algorithms Draft Policy Liz Toy reported that there are productivity plans being developed by the CRG. This include the use of chemotherapy after disease progression These will be discussed the next meeting The response to the Draft policy by the SW Cancer Network raised the issue of access to drugs for patients, where there is no national policy, but the request represents a cohort decision. It is the view of the Group that the national policy creates a loop whereby some patients are denied a decision. (details in the Network response) Breast & myeloma algorithms There was broad agreement that these algorithms are reasonable but it would be better to include known alterations for certain patients groups (such as those with impaired organ function). Liz Toy has raised this issues with the CRG Liz Toy also reported that more algorithms will be circulated in the next few months. The process should be complete within a year. Oncologists can register as a stakeholder with the CRG.

4 SW Network Protocols Jon Miller noted that some of the requirements for protocols (drugs, dosage, days and routes) are included in the draft national algorithms. This means that the additional information required locally is about tests, dose modifications and supportive therapy. Sue Mulvenna reported that the review of local governance was positive. Sue will collate the responses and share with the Group. The site specialisations of local oncologists will be collated. These Groups will be asked to identify protocols that need to be revised, and to sign off the revisions. SueM SarahM Network Support Sarah Murdoch is now supporting the Network one day a week. 5 Chemotherapy - Clinical Outcomes and Patient Experience The National Chemotherapy Patient Experience Survey will be discussed at the next meeting The group will agree a small number of clinical outcomes that can be reviewed using data from the National dataset. This will be also be informed by CRG productivity proposals and information on the use of drugs funded by the Cancer Drug Fund 6 Specific Therapy issues 1. KRAS Testing & cetuximab NHS England will fund RAS testing 2. Oncotype DX NHS England is reviewing its policy but at present this is not routinely funded. See discussion on national algorithm policy for comments on NHS England s policy, which is relevant to this decision 3. Denosumab There is some debate amongst clinicians as to the use of this drug. NICE may also be reviewing its decision in light of the comparator drug now being cheaper (the patent has expired). If this drug is used it is more suitable to be administered in the community (by subcutaneous injection) 4. Sub-cutaneous rituximab Providers will be switching to sub-cutaneous route for certain indications only (led by the where the sub-cutaneous route was tested in a trial). 5. Healthcare at Home The issues with this home chemotherapy provider were discussed. It was agreed that this needs to be resolved or providers will need to bring this chemotherapy back in-house. 7 Work Programme 1. National Chemotherapy Patient Survey 2. Identification of Chemotherapy Clinical Outcomes 3. Revision of local protocols 4. Review of practice against CRG productivity proposals

5. Development of process to move more drug administration into community (eg Denosumab). 8 Future Meetings confirmed dates: - 15 October 2014, South West House, Taunton @ 10.30am 1.30pm - 11 February 2015, South West House, Taunton @ 1pm 4pm

Appendix 1 Attendance and Apologies Name Position Organisation Present Jonathan Miller Cancer Network Manager South West Strategic Clinical Network Chair Alastair Whiteway Clinical Director - Cancer Northern Devon Healthcare NHST Yes Ali Snell Lead Chemotherapy Nurse Taunton & Somerset NHSFT Yes Alison Hatton Sister Weston Area Health NHST Yes Andrea Preston Divisional Pharmacist Haem-Onc University Hospitals Bristol NHSFT Yes Charlotte Overney Lead Cancer Nurse Northern Devon Healthcare NHST Yes Clare Barlow Head of Service Taunton & Somerset NHSFT Yes Elizabeth Toy Consultant Clinical Oncologist & South West representative on the National Royal Devon & Exeter NHSFT Yes Chemotherapy Clinical Reference Group Emma Thoms Chemotherapy Unit Manager Northern Devon Healthcare NHST Yes Geoff Cogill Consultant Clinical Oncologist Plymouth Hospitals NHST Yes Helen Thomas Clinical Director - Cancer South West Strategic Clinical Network Yes Jonathan Cullis Head of Service Salisbury NHSFT Yes Kate Scatchard Chemotherapy Lead Royal Devon & Exeter NHSFT Yes Kathy Beard Pharmacist Weston Area Health NHST Yes Libby Hardy Oncology Pharmacist Royal Devon & Exeter NHSFT Yes Maria Grosvenor Lead Chemotherapy Nurse Yeovil District Hospital NHSFT Yes Marjorie Tomlinson Head of Service Weston Area Health NHST Yes Nyasha Manomano Cancer Services Pharmacist Northern Devon Healthcare NHST Yes Philip Dunn Specialist Pharmacist Plymouth Hospitals NHST Yes Rebecca Toghill Lead Chemotherapy Nurse North Bristol NHST Yes Rufus Smith Lead Pharmacist Yeovil District Hospital NHSFT Yes Sam Brenton Lead Chemotherapy Nurse South Devon Healthcare NHST Yes Sarah Murdoch Senior Oncology Pharmacist University Hospitals Bristol NHSFT Yes Sue Mulvenna SCN Pharmacist South West Strategic Clinical Network Yes Tracey Williams Lead Pharmacist Specialised Commissioning SW Yes Alan Leach North Bristol NHST Apologies Becky Bagnell Haematology Pharmacist North Bristol NHST Apologies Belinda Mills Lead Chemotherapy Nurse Salisbury NHSFT Apologies Birgit Cloos Oncology Pharmacist Plymouth Hospitals NHST Apologies Clare Fox Haematology Nurse Specialist Royal Devon & Exeter NHSFT Apologies Debbie Hart Senior Service Specialist Specialised Commissioning SW Apologies

Deborah Turner Consultant Haematologist South Devon Healthcare NHST Apologies Debra Robertson Oncology Pharmacist Salisbury NHSFT Apologies Geoff Sparrow Oncologist Yeovil District Hospital NHSFT Apologies Helen Daggar Matron Royal Devon & Exeter NHSFT Apologies Jeremy Braybrooke Consultant Oncologist University Hospitals Bristol NHSFT Apologies Khalia Lancaster-Thomas Assistant Divisional Mgr - Planned Care Weston Area Health NHST Apologies Lyndel Moore Interim Lead Cancer & Chemotherapy Nurse Great Western Hospitals NHSFT Apologies Martyn Blundell Lead Oncology Pharmacist South Devon Healthcare NHST Apologies Neil Toghill Royal Devon & Exeter NHSFT Apologies Oonagh McGrath Pharmacy Manager University Hospitals Bristol NHSFT Apologies Rachael Herrington Chemotherapy Lead Nurse University Hospitals Bristol NHSFT Apologies Rachel Bryce Plymouth Hospitals NHST Apologies Sarah McGlue Lead Chemotherapy Pharmacist Great Western Hospitals NHSFT Apologies Sarah Wellington Chemotherapy Lead Plymouth Hospitals NHST Apologies Sue Watts Lead Pharmacist Gloucestershire Hospitals NHSFT Apologies Suzanne Wright Cancer Services Manager Gloucestershire Hospitals NHSFT Apologies Teresa Coombes Cancer Manager Yeovil District Hospital NHSFT Apologies Tina Grose Lead Cancer Nurse Royal Devon & Exeter NHSFT Apologies Tracey Cullerne Modern Matron / Lead Nurse Oncology Gloucestershire Hospitals NHSFT Apologies Cheryl Bradly Chemotherapy Sister United Hospitals Bath NHST Corrine Thomas Lead Nurse Weston Area Health NHST Fran Lowery Cancer Services Manager Royal Devon & Exeter NHSFT Ian Ingeldew Consultant Nurse Gloucestershire Hospitals NHSFT Jarrod Dunn Oncology Pharmacist Taunton & Somerset NHSFT Karen Skelley Senior Sister Royal United Hospital Bath NHST Lisa Nicholls Macmillan Chemotherapy CNS Royal Cornwall Hospitals NHST Nick Reed Consultant Clinical Oncologist Gloucestershire Hospitals NHSFT Steve Collings Modern Matron Plymouth Hospitals NHST