RESEARCH GRANT APPLICATION

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RESEARCH GRANT APPLICATION ALL APPLICATIONS SHOULD BE RECEIVED BY JANUARY 31, 2019

Page 2 of 7 General Guidelines and Policies for Grant Submission Introduction The National Pancreas Foundation (NPF) is a private, non-profit organization established to support the funding of research related to pancreatic diseases. It also provides support for the men, women, and children who are suffering from diseases of the pancreas. Grant Eligibility Criteria Applicant Criteria Applicants must be employed by an institution engaged in health related research. Be a physician or hold an advanced degree (MD, DO, PhDor international equivalent) working in any country within 10 years of obtaining his/her medical degree at the time of grant submission. In cases of a change in institutions while applying for, or utilizing funds from the NPF, applicants must notify the NPF, and will be subject to review based upon the change in circumstances. Collaborations with more senior scientists in an advisory or mentorship role during this project are viewed favorably during the review process. Research/Grant Criteria The research must be in the field of pancreatic diseases. Studies intended to advance knowledge in the areas of pancreatic carcinoma, and all forms of pancreatitis would be the closest to the areas of interest of the NPF. Grant research proposals should directly address questions in basic, experimental or translational pancreas disease research, including, but not limited to acute, chronic, & pediatric pancreatitis, pancreatic cysts, pancreatic insufficiency, early detection and pancreatic cancer. Investigators should be in the early stages of their career. Studies more closely related to diabetes will not be accepted. It should be clearly specified how the funds/research will be used to leverage additional funding The funding should be for a pilot project, where the results lead to valuable preliminary data that could lead to a larger grant that could be transformative. The scope of work must be commensurate with the funding amount (PI s should not be sending in RO1 type applications). Overlap with existing sources of funding should be clearly identified in the Other Support document Terms Grants will be made for one year only. The maximum award will be $50,000 for one year. Funding is to cover direct costs only, and costs should be reflected in the budget.

Page 3 of 7 Selection Criteria All proposals received and accepted for review will be reviewed by the Grant Review Council. The members of this committee are all physicians/researchers with special interests in the field of pancreatic diseases. They will review the proposals and make recommendations for funding based on the merit of the proposed research, including its relevance to the field of pancreatic diseases. The Committee will make a report to the Boards of Directors. Only by vote of the Board can proposals be accepted for funding. Applicants will be notified as to the actions of the Board soon after they meet. Non-Profit Statement The NPF is a non-profit organization under Section 501 (c)(3) of the Internal Revenue Code. Funding can only be granted to institutions that can attest to their similar non-profit status. Preparation Preparation and Submission of Application Applicants should complete the original Research Grant Application provided by the NPF and submit the application online using a single electronic file (Microsoft Word or Adobe PDF format). The application format should be as follows using the headings listed below. Title; Name and Affiliation of PI and all key investigators Abstract: limited to 300 words; The Abstract portion of the application should contain enough information to adequately explain the project and its relevance to the pancreas. This page should also contain 3-5 key words or phrases that best describes the application Grant Content to be restricted to 3 pages (1 margins and Arial or similar font with minimum 11 size) and organized as follows: Literature cited. Specific Aims, Background and Significance, Preliminary Data, Proposed Studies and Methods. Budget Justification: Not more than one page. Justification for salary support and supplies and equipment listed in the budget page should be detailed. Biosketch and Other Support (maximum of 5 pages) should be submitted in NIH format for the Principal Investigator and other investigators listed in the application. Potential overlap with other funding should be clearly detailed. Overlap with existing sources of funding should be clearly identified in the Other Support document.

Page 4 of 7 The Principal Investigator and the Institutional Representative must sign the application before it will be accepted for review. The budget should be inclusive and for direct costs only. Justification is needed for all equipment purchases over $ 500. The Attestation Statement must be read and signed by the Principal Investigator. Item number 8 refers to the Investigator s commitment that the research will be conducted under the supervision of an Institution at which appropriate standards and oversights are working. Submission The entire grant application should be submitted in a single electronic file in Microsoft Word or Adobe PDF format. It must be submitted from the NPF website at: http://www.pancreasfoundation.org/research/research-grant-application/. Notification The notification of the decision of the Board of Directors regarding funding will be mailed to the applicant and the Institutional Representative after the Board meets, usually in April. ALL APPLICATIONS SHOULD BE RECEIVED BY JANUARY 31, 2019 Date: Title of Project: Total Amount Requested: $

Page 5 of 7 Principal Investigator: Official of Institution: Last name, first name, initial, degree Last name, first name, initial, degree Title Title Name of Institution Name of Institution Department Department Number and Street Number and Street City, State, and Zip Code City, State, and Zip Code Telephone and Fax numbers Telephone and Fax numbers Email Address Email Address It is the responsibility of the institution to assure that the activities funded by this grant are properly carried out in accordance with the guidelines established by the U.S. Department of Health and Human Services. This assurance is verified by the signature of the Official signing below: Signature Signature of Official _ Date _ Date _

Page 6 of 7 Budget Personnel Salaries $ Benefits Equipment Supplies (group in categories) Miscellaneous (list specifics) TOTAL AMOUNT REQUESTED (MUST match amount on page one)

Page 7 of 7 Attestation Statement Regarding Indirect and Duplicate Costs 1. By affixing my signature below, I attest that I have read and will follow the following principles with regard to funding supplied to me by the National Pancreas Foundation (NPF). 2. The funds that I have applied for will be used to fund only the direct costs of the proposed research for which I am applying. I understand that at this time no funds are available for indirect costs. 3. I further understand that if duplicate funding for this project is obtained, at any time that I will immediately inform the NPF and withdraw my request for funding. In the event that any portion of the project is now being funded by, or in the future is funded, by another source, I will fully disclose that to the NPF. 4. Application shall be on the form provided by the Foundation. If the application is made by a research organization, such organization must be exempt from federal taxation under Section 501 (c)(3) of the Internal Revenue Code and must provide a copy of the determination letter issued by the Internal Revenue Service granting such exempt status. 5. The principle area of investigation shall be in the area of pancreatic disease and the proposed research shall serve to advance existing pancreatic disease research in accordance with Section 501 (c)(3) of the Internal Revenue Code. 6. The principal investigator s institution will be responsible for certifying to the Foundation that the research is conducting in accordance with current medical research standards and that is in compliance with the current guidelines of the U.S. Department of Health and Human Resources regarding Vertebrate Animals, Recombinant DNA, Research Misconduct, and Financial Conflict of Interest. The institution will further verify that any research involving human subjects or vertebrate animals has been approved by the necessary review boards and committees, in accordance with existing laws and regulations. 7. The Principal investigator shall submit a budget with the application and justification for budgetary items exceeding $500. 8. The Principal investigator shall be required to submit a final financial report as well as a written summary of research results listing all publications in which the findings have been published. Principal Investigator Date