Canada s Strategy for Patient- Oriented Research (SPOR) SPOR Networks in Chronic Disease

Canada s Strategy for Patient- Oriented Research (SPOR) SPOR Networks in Chronic Disease

CORE ELEMENTS OF SPOR Support for People and Patient-Oriented Research and Trials (SUPPORT) Units SPOR Networks Capacity development Improving the clinical trials environment Patient engagement

SPOR Networks National collaborations of patients, health professionals, decision makers, health researchers and other stakeholders to generate evidence and innovations designed to improve patient health and health care systems

SPOR Networks in Chronic Disease This funding opportunity will provide support for the development and implementation of SPOR Networks in noncommunicable Chronic Diseases. For the purpose of this opportunity, non-communicable chronic disease is defined as a long-term disease that is not passed from one person to another; it evolves over time, often progressing in severity. Although a non-communicable chronic disease may be prevented and can often be controlled, it is rarely cured.

Focus of the Networks Anchored on the challenges in Valley 1 research as it bridges to Valley 2. First-in-human and beyond research in non-communicable chronic diseases that have resulted in areas of high disease burden. Networks are strongly encouraged to explore the opportunities for impact across multiple non-communicable chronic diseases. No more than one network will be funded in any particular focus area. Successful networks are expected to include relevant international collaborations.

Objectives The primary objective of the opportunity will be to translate existing and new knowledge generated by basic biomedical, clinical, and population health research into testing of innovations that can improve clinical science and practice and foster policy changes, leading to transformative and measureable improvements in patient health outcomes, and in efficiency and effectiveness healthcare delivery within five years.

Objectives Network applicants will be expected to show that the planned program of research and knowledge translation will have a significant impact on non-communicable chronic diseases and their co-morbidities by: Addressing patient-oriented research priorities and developing an interdisciplinary nation-wide agenda of outcomes-oriented research. Accelerating the translation of existing and new knowledge generated by basic biomedical, clinical, and population health research into clinical science and practice and policy applications. Strengthening the capacity to conduct patient-oriented research through an integrated multidisciplinary program that provides unique and innovative training and mentoring opportunities. Fostering the development and implementation of evidenceinformed and gender-responsive practices, policies, services, products and programs to improve patient outcomes, access to care and quality, please efficiency dial 1-877-413-4788, and effectiveness of health care.

Process and Timeline Phase Major Step Key Points Timeline Phase Important I Registration dates: Administrative only and will be used to facilitate reviewer recruitment December 2014 (Deadline 2014-12-02) Letter of Intent Reviewed by an international panel of experts Top 20 in the fundable range will be provided with a $50K development grant and will be invited to a strengthening workshop January March 2015 (Deadline 2015-01-13) Phase II Strengthening Workshop(s) Mandatory for all successful LOIs Workshop to help strengthen applications and encourage dialogue between applicants Spring 2015 Phase III Full Application Full applications submitted and reviewed Four distinct chronic disease networks are funded October 2015 January 2016 (Deadline 2015-10-15)

Funds Available Each successful network will receive up to $12,500,000 over five years from CIHR. Up to 20 Development Grants will be funded through the Letter of Intent stage. Each Development Grant will have a maximum value of $50,000. Partner funds are NOT required at this stage. Up to 4 Networks will be funded through the Full Application stage. CIHR will provide up to $12.45M over five years per Network. Funds must be matched 1:1 with non-federal sources of funding.

Funds Available Funding from an international source that does not flow or is not made accessible to a Canadian component of the network is not eligible to be counted toward the 1:1 matching requirement. Clinical trials are welcomed as a component of a network s proposed program of research.

Eligibility The Nominated Principal Applicant must be one of the following: An independent researcher affiliated with a CIHR eligible institution. A knowledge user affiliated with a CIHR eligible institution. Each network must include distinct representatives from each of the following groups (i.e., one individual representing one group or discipline a minimum of six individuals, including the Nominated Principal Applicant): Researchers (minimum of three and each from a different discipline) Health care professionals Patients/family representatives/informal care providers Health policy makers

Eligibility The network must demonstrate that it will be pan-canadian in scope, i.e., that it includes Principal Applicants (key members), from a minimum of one province or territory in three of the following four regions: East includes Newfoundland and Labrador, Nova Scotia, Prince Edward Island and New Brunswick Central includes Quebec, Ontario and Manitoba West includes Saskatchewan, Alberta and British Columbia North includes Nunavut, Northwest Territories and Yukon

Performance Measurement Each network will be expected to be outcomes driven, with clearly defined goals and associated metrics to measure progress. CIHR will require funded networks to provide annual reporting on agreed upon performance measures. The network will be required to participate in any other evaluation or performance measurement activities deemed necessary by CIHR.

LOI Evaluation Criteria Categories 1. Vision, rationale, priorities and added-value 2. Potential for transformative impact 3. Patient-oriented research program 4. Strength of the team 5. Patient-oriented research training and mentoring strategy 6. Knowledge translation plan 7. Partnership plan 8. Governance

Application Process Step 1 - Registration: by email to lisa.lemieux@cihr-irsc.gc.ca Names and institutions of all applicants known at the time of registration. Chronic disease(s) that will be the focus of the research and known objectives of research. Keywords that will inform the areas of expertise needed to recruit reviewers. Registration is mandatory to be able to submit a Letter of Intent.

Application Process Step 2 - Letter of Intent: on ResearchNet Please note: A maximum of five (5) Canadian Academic Common CVs or Knowledge User CVs will be accepted Key participants that fall in the Patient/family representatives/informal care providers stakeholder group are required to provide testimonials (max 2 pages each) describing their relevant lived experiences in the context of the application Further details on the Strengthening Workshop and the Full Application process will be released in the coming months.

For more information: For more information, the full funding opportunity can be found on the Funding Opportunity Database For questions on CIHR funding guidelines, how to apply, and the peer review process contact: Lisa Lemieux, Program Delivery Coordinator Telephone: 613-948-2398 Email: lisa.lemieux@cihr-irsc.gc.ca For questions about this initiative and research objectives contact: Erica Dobson, Associate Telephone: 613-946-7656 Email: erica.dobson@cihr-irsc.gc.ca