INFORMATION & INVITATION TO PARTNER

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INFORMATION & INVITATION TO PARTNER The ISN offers a substantial portfolio of visibility opportunities, but we are happy to discuss with potential partners about other visibility opportunity that might be of more interest. ISN Frontiers Meeting Information & Invitation to Partner - V3 1

2019 ISN Frontiers Meeting ISN Frontiers Concept ISN Frontiers Meeting is our new and exciting ISN meeting concept and offers a unique setting where we will bring together basic, translational & clinical researchers, medical and other scientists, clinicians and allied healthcare practitioners all of whom are interested in a specific scientific area. The meeting will provide excellent in-depth discussions and learning opportunities, created with the intention of fostering collaboration, and challenging colleague an opportunity not to be missed. This new event format will make available cutting-edge science to the global community while breaking down cross-regional barriers and providing access to the latest knowledge and expertise. The ISN Frontiers provide excellent opportunity for high-level scientific discussions, debate, interactive sessions and career discovery opportunities. ISN Frontiers meetings are aimed at a global audience from established researchers and clinicians, as well as early career professionals who are in the process of developing a network and collaborations. Young researchers and clinicians will be provided with opportunities to present and discuss their work during the meeting as well as interact, learn, and network with more established professional in the field. ISN Frontiers will provide an opportunity for high level publications to be generated from this meeting, in order to ensure dissemination of the results and summarize the unique outputs from such a meeting. CPR - Cardio-Pulmonary-Renal interactions and their interdependence in disease The 2019 meeting will be the second meeting in our new and exciting ISN meeting concept and it will a true cross-disciplinary event, bringing together clinicians, scientists and epidemiologists working in nephrology, cardiovascular and respiratory medicine. Cardio-renal syndrome describes and classifies the various interrelationships between the heart and the kidneys; however, the link between diseases involving the heart, the lungs, and the kidneys requires investigation to unravel potentially novel and common pathophysiological mechanisms. Through an interactive and high-quality scientific program, the ISN Frontiers meeting will: - Present the latest cutting-edge science and innovation in kidney-heart-lung function and disease - Increase awareness and recognize the interactions among the kidneys, the heart, and the lungs that can impact the development of systemic disease and co-morbidities. - Cultivate and develop novel concepts in the pathogenesis of kidney disease and its related complications associated with chronic kidney disease and transplantation in a wider context - Provide a unique platform for active interactions among the three disciplines and foster cross-disciplinary research collaborations to further our understanding of the important connections between the kidneys, the heart, and lungs. - Stimulate new hypotheses for translational research and identify opportunities and targets for developing new therapies. - Promote collaborative clinical trials across the three clinical disciplines and encourage a more holistic view and approach to diseases affecting the three organs systems. Through a better understanding of the underlying pathophysiological mechanisms linking the kidneys, heart, and lungs, ISN Frontiers Gothenburg 2019 hopes to shift the disease paradigm to identify new disease pathways, and potentially novel treatment targets for more effective therapies in renal disease, and its frequent cardiac and pulmonary co-morbidities. ISN Frontiers Meeting Information & Invitation to Partner - V3 2

Key dates Location Audience Committee The 2019 ISN Frontiers organizing and scientific program committee includes: Jenny Nyström, University of Gothenburg Sweden (Chair) Angela Yee Moon Wang, University of Hong Kong Queen Mary Hospital, Hong Kong (Co-Chair) Boye L. Jensen, University of Southern Denmark (Co-Chair) We are aiming to attract 500 participants working within the Cardiac, Pulmonary and Kidney research communities who will, together, discuss, update, debate and learn about research within CPR Interactions. The program will be of special interest to cardiovascular, pulmonary and renal physiologists, pharmacologists, cell biologists and immunologists; cardiologists, critical care and respiratory physicians, and nephrologists; PhD students, post-doctoral and clinical research fellows. Gothia Towers Mässans gata 24 412 51, Gothenburg Sweden Website: www.gothiatowers.com Tel: +46 31 750 88 00 February 2019 June 2019 Registration and hotel reservation live Call for abstracts submissions opens Abstract submission deadline Early bird registration deadline ISN Frontiers Meeting Information & Invitation to Partner - V3 3

Invitation to partners ISN offers partners a format of meetings that allows for maximum interaction and networking with a highly-focused target audience to avoid having to compete for their attention with hundreds of other companies with possibly bigger budgets and different interests. ISN is committed to providing equal exposure and visibility to its partners by offering comprehensive packages that allow them maximum recognition and exclusive interaction with a highly-focused target audience. It also helps partners to actively participate in creating new insights, knowledge and applications. We hope that the meeting will raise your interest and you will be interested in supporting it. The ISN offers a substantial portfolio of visibility opportunities, but we are happy to discuss with potential partners about other visibility opportunity that might be of more interest. For more information about the ISN Frontiers meeting on CPR - Cardio-Pulmonary-Renal interactions and their interdependence in disease and the available sponsorship opportunities, please contact: Mr. Matthieu Van der Straten ISN Meetings and Events Director International Society of Nephrology 1 Rue des Fabriques 1000 Brussels, Belgium Tel. +32 2 808 04 20 Fax. +32 2 808 44 54 Email: mvanderstraten@theisn.org www.theisn.org ISN Frontiers Meeting Information & Invitation to Partner - V3 4

SPONSORSHIP OPPORTUNITIES SPONSORSHIP PACKAGES Gold 60.000 EUR Pag. 6 Silver 45.000 EUR Pag. 6 Bronze 25.000 EUR Pag. 6 SPONSORSHIP OPTIONS Choose one or more items from the list below and create your customized sponsorship package Lunch and Evening Symposia 30.000 EUR Pag. 7 Advisory Board meeting 25.000 EUR Pag. 8 ISN Frontiers lanyards 9.000 EUR Pag. 8 Water Station 7.500 EUR Pag. 8 Coffee break sponsorship 5.000 EUR Pag. 8 Charging station 5.000 EUR Pag. 9 Exhibition Space From 4.950 EUR Pag. 9 Hanging Banners 2.500 EUR Pag. 9 Fellowship grants 2.000 EUR Pag. 10 Frontiers Meeting news advertisement 1.500/2.000 EUR Pag. 10 Advertisement Opportunity (1/2 page A4) 2.500 EUR Pag. 10 ISN Frontiers Meeting Information & Invitation to Partner - V3 5

Gold sponsorship 70.000 EUR This package is available to maximum of three partners chosen on a first-come, first-served basis. A) Choose between two options: 1) One Industry Lunch symposium (please see page 7 for more details) or 2) A 90 minutes Advisory Board meeting with Key Opinion Leaders (please see page 8 for more details) B) The following items are included in your package 27m² of exhibition space Five complimentary full registrations Complimentary hospitality suite for 10 people to include basic audio-visual equipment. Any catering and additional audio-visual equipment is charged at the sponsor s expense. Recognition on intermission slides and on site prominent signage Visibility on the ISN Frontiers website including company profile and contact information Option to promote the meeting announcing the partnership with ISN Hanging Banner (1) Frontiers Meeting news advertisement Advertisement Opportunity (1 page A4) Silver sponsorship 45.000 EUR Sponsors booking sponsorship for a total of EUR 45.000 will be acknowledged as SILVER sponsors and will have their company logo visible on the ISN Frontiers website. X. Silver sponsorship excludes registrations. Bronze sponsorship 25.000 EUR Sponsors booking sponsorship for a total of EUR 25.000 will be acknowledged as BRONZE sponsors and will have their company logo visible on the ISN Frontiers website. X. Bronze sponsorship excludes registrations. ISN Frontiers Meeting Information & Invitation to Partner - V3 6

Industry Lunch and Evening Symposia- 30.000 EUR Industry Lunch Symposia are commercially supported educational activities held during the ISN Frontiers Meeting. They are offered in slots according to the following schedule DATE TIME MEETING ROOM NAME RATE Friday Oct 4 13h00 14h30 Congress Hall EUR 30.000 Saturday Oct 5 13h00 14h30 Congress Hall EUR 30.000 Friday Oct 4 18h30 20h00 Congress Hall EUR 30.000 Saturday Oct 5 18h30 20h00 Congress Hall EUR 30.000 The scientific part of the symposium is limited to maximum 60 minutes. The remaining time is to be used for lunch/dinner serv ice. Symposia organizers are required to serve (box) lunch/dinner as part of the symposium program, at their own cost. The rental fee includes: Room rental Standard setup: in theatre style with stage, lectern and speaker table(s) Basic AV equipment & services: amplification data projection technician Publication for the symposium program on the Frontiers Program Book (1/2 page) * Use of official Frontiers logo on invitations and promotional documentation One time use of the pre-registration e-mailing list on month prior to the Frontiers meeting Sponsor will supply the content of email, ISN will send it out to delegate database Submission Industry symposia will only be accepted after final approval by the Frontier s scientific program committee. Program proposal s should be received no later than March 2019. More details on the submission process will be made available on due time. Acceptance and Confirmation Once the program drafts have been evaluated and accepted a confirmation letter will be sent. Final Program The final program should be sent to the Congress office (IPASTORINO@THEISN.ORG) no later than June 03, 2019 to be included in the Congress material. This final program should include all details of speakers and chairpersons. * Info to be provided at the latest by June 3, 2019 to be published on the program book ISN Frontiers Meeting Information & Invitation to Partner - V3 7

Advisory Board meeting 25.000 EUR ISN offers the following Advisory Board meeting package on a first-come, first served basis. A 90-minute meeting with Key Opinion Leaders (KOLs) chosen by the sponsor from a list provided by the ISN. Only KOLs invited by ISN in conjunction with the Frontiers meeting can be approached. The number of KOLs invited is defined with the sponsor (5 KOLs maximum). A meeting room is provided, with audio-visual equipment, refreshments and light snacks. All logistics (invitations and meeting room) are managed by ISN. ISN Frontiers lanyards 9.000 EUR* Opportunity for one company to have its corporate logo printed on the symposium lanyards. Only corporate company information, no specific product information is allowed on the lanyards (estimated print run: 650 lanyards) Acknowledgement on the ISN Frontiers website (*) includes production costs of the lanyards Water Stations 7.500 EUR* Water stations (3 stations) will be placed throughout the congress facilities providing participants with complimentary access to fresh drinking water. Sponsor benefits: Acknowledgment on the congress website Logo recognition at each station (*) includes costs water and cups (*) option not exclusive Coffee break sponsorship 5.000 EUR (per day) Support the networking moments during ISN Frontiers meeting and take advantages of the following visibility Company logo exposure during the sponsored food and beverage functions (logo on tables and two roll-up banners* in the coffee break area) Acknowledgement on the ISN Frontiers website and program book Recognition on intermission slides (*) roll-up banners to be provided by sponsors ISN Frontiers Meeting Information & Invitation to Partner - V3 8

Exhibition space Take advantage of the nephrology, cardio and pulmonary research community s presence at the ISN Frontiers meeting and showcase your products and services. The exhibition space options include: Two complimentary passes for the symposium Acknowledgement on the ISN Frontiers website and program book Space only rate (minimum 9m²) 550 EUR per m². Space only rate cover floor space only. It does not include the construction of a modular booth, carpet, electricity, mandatory insurance or any other extras. Shell stand package at 5.500 EUR (includes surface of 9m²) A special package including the shell scheme structure and basic furniture for 9m² Schell scheme spaces larger than 9m² can be quoted upon request The package includes: 1 counter; 1 brochure stand, 1 high table (white), 3 bar stool (white) 1 folding door (1 m), 1 carpet to rent (blue), 1 spotlight system (white) 1 fascia (white with black text), 1 power point 10A, 240 V (2000 W) Hanging Banners 2.500 EUR Several banner locations are available for added branding exposure in high traffic areas of the venue, mainly the registration foyer. Design must be submitted in digital format and requires ISN s approval. The banner sizes are 90cm wide and 3meters length. Price per banner and includes production, installation and dismantle. Fellowship grants 2.000 EUR Support the meeting and support ISN mission! Allow as many delegates as possible from low-income and low-middle-income countries to attend the Frontiers Meeting. Fellowship grants will help us cover the cost of inviting young and deserving nephrologists who will strongly benefit from attending this cutting-edge event. The price is per grant. In return for this generous support, a special mention of our supporters and contributors will be published on the website and ISN Frontiers program book. The grant covers: Registration to Frontiers Meeting Economy return flight to Gothenburg Accommodation ISN Frontiers Meeting Information & Invitation to Partner - V3 2

Frontiers Meeting news advertisement The Frontiers meeting newsletter is circulated to registered delegates. It features the program highlights and useful information about travel and accommodation. This is a great opportunity to relay your message and promote your activities and presence at the Frontiers Meeting. Rates: Newsletter July 2019 Newsletter August 2019 Newsletter September 2019 1,500 EUR 1,500 EUR 2,000 EUR Please note that sponsorship is allocated on a first-come first served basis. Due to the popularity of the meeting, we ask sponsors to order their items of choice as soon as possible to avoid disappointment. Advertisement Opportunity (1/2 page A4) - 2.500 EUR Opportunity for companies to provide a half page (A4) full color advertisement to be placed in the symposium final program book. ISN Frontiers Meeting Information & Invitation to Partner - V3 2

ISN FRONTIERS MEETING SPONSORSHIP ORDER FORM Company name: Click here to enter text. Sponsoring organization: contact information Contact person: Click here to enter text. Address 1: Click here to enter text. Address 2: Click here to enter text. City: Click here to enter text. Country: Click here to enter text. Telephone: Click here to enter text. Zip code: Click here to enter text. VAT no. (if applicable): Click here to enter text. Email: Click here to enter text. Types of sponsorship and sponsorship items (please tick ) Gold sponsorship package at 70.000 EUR Advertisement Opportunity (1/2 page A4) Industry Lunch and Evening Symposia at 30.000 EUR Exhibition Friday October 4, 13:00-14:30 18:30-20:00 Exhibition space only at 550 EUR per m² Saturday October 5, 13:00-14:30 18:30-20:00 Shell stand package at 5.500 EUR n. of m². Advisory board at 25.000 EUR Hanging Banners at 2.500 EUR ISN Frontiers Lanyards 9.000 EUR Fellowship grant at 2.000 EUR Water Station 7.500 EUR Fellowship grant at 2.000 EUR n. of grants:. Coffee break sponsorship at 5.000 EUR (per day) Friday October 4, 13:00-14:30 Saturday October 5, 13:00-14:30 Advertisement Opportunity (1/2 page A4) Frontiers Meeting news advertisement Newsletter July 2019 at 1.500 EUR Newsletter August 2019 at 1.500 EUR Newsletter September 2019 at 2.000 EUR Subtotal amount sponsorship: EUR: Total amount due: EUR: ISN Frontiers Meeting Information & Invitation to Partner - V3 3

Payment information We prefer to pay via following payment method Total Amount:. Bank transfer within 30 days of receiving the invoice Credit card (VISA/AMEX/Master/EU) Credit card number: Name on card: Expiry date: CSV Code: Cancellation policy A full refund can be made if the cancellation request is received in writing by October 15, 2018, baring 100 EUR administration fees A 50% refund can be made, if the cancellation request is received in writing before January 14, 2019 100% of the sponsorship amount, if the cancellation request is received after 14 January 2019. Unexpected cancellation The organizer reserves the right to cancel the meeting without prior notice or compensation in the unfortunate event of a strike, fire, terrorist attack, damages or other fatalities. The organizer cannot be hold responsible in such circumstances. Limits of liability In the unfortunate event that the organizer has to cancel the congress due to a major incident, such as a strike, fire, terrorist attack, damages or other fatalities, as long as these arise from a cause beyond ISN's control, payment will be reimbursed subject to a deduction of any costs incurred in preparing the event. Please complete and return the forms by email to: ipastorino@theisn.org Date Signature ISN Frontiers Meeting Information & Invitation to Partner - V3 4