CIHR: The Changing Landscape University of Toronto Grant Writing Workshop June 18, 2015

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CIHR: The Changing Landscape University of Toronto Grant Writing Workshop June 18, 2015 Philip M. Sherman, MD, FRCPC Scientific Director CIHR Institute of Nutrition, Metabolism and Diabetes

CIHR Virtual Institutes

CIHR Approach: Problem-based, Multidisciplinary, Results-Oriented CIHR efforts are underpinned by excellence funding decisions are all made through peer review CIHR takes a problem-based and multidisciplinary approach to the health challenges facing Canadians Multi-faceted approach encompasses research in across the research continuum: Biomedical (Theme 1) Clinical (Theme 2) Health systems and services (Theme 3) Population and public health (Theme 4) CIHR is committed to facilitating research results into action and to working collaboratively with partners

Applying to CIHR Funding Opportunities Open Operating Grants Program (OOGP) Investigator-initiated research proposals Any area of health research ~ 70% total funding Strategic Funding Opportunities Priority areas identified by Institutes, Branches ~ 30% total funding e.g. operating grants from the open competition (OOGP) e.g. Programmatic Grants in Food & Health and Environments, Genes and Chronic Disease

Open Program: Rationale for Proposed Changes A number of challenges have been identified: CIHR believes that re-designing the Open Suite of Programs and Peer Review System will help address these challenges

A New Open Suite of Programs To address these challenges, the existing suite of open funding programs is being reorganized into two new schemes: Open Operating Grant Program Partnerships for Health System Improvement Knowledge Synthesis Knowledge to Action Proof-of-Principle I & II Industry-Partnered Collaborative Research New Investigator Program Project Scheme: projects with a specific purpose and defined endpoint Foundation Scheme: innovative, highimpact programs of research To support the implementation of the new funding schemes, CIHR will also establish a College of Reviewers that will support excellent peer review across the spectrum of health research. 6

What will be achieved through the Reforms? The objectives of the reform to CIHR s investigator-initiated programs and peer review processes are to: Capture excellence across all four research pillars, from knowledge creation to knowledge translation Capture innovative, original and breakthrough research Integrate new talent to sustain Canada s pipeline of health researchers Improve sustainability of the long-term research enterprise In meeting these objectives, the Reforms are also meant to address a number of current operational challenges: Workload and costs for applicants Peer review burden Lack of consistency and efficiency of peer review process Growing discrepancy between research evolution and committee structure Program complexity

Transition Plan The transition to the new Open Suite of Programs is a multi-year process that includes gradually phasing-out existing Open programs, phasing-in new programs and piloting key elements of the new design. Piloting is an important step to allow CIHR to adjust and refine processes and systems in order to best support applicants and reviewers. CIHR is using a number of existing competitions to run the pilots so that we can properly train applicants, orient reviewers, and monitor outcomes in a managed fashion. Fellowships program Knowledge Synthesis (KRS) Partnerships for Health System Improvement (PHSI) Knowledge to Action (KAL) 8

Design Elements Multi-stage competition process Effective screening of applications Decrease applicant burden and reviewer burden Focus reviewer attention on specific criteria at each stage Application- Focused Review Avoid force fitting applications into standing committees Assign appropriate expertise to each application Structured Review Criteria Minimize inconsistent application of review criteria Improve transparency of review process Decrease peer review burden Remote (virtual) Screening/Review Facilitate access to expertise, including international Improve cost-effectiveness of the process Minimize group dynamics and committee culture biases 9

Transition timeline The transition to the new Open Suite of Programs and peer review processes will occur over a number of years Course corrections and adjustments may be required along the way as we learn from the results of the pilots 10

The Foundation Scheme The Foundation Scheme is designed to contribute to a sustainable foundation of health research leaders. It is expected to: Support a broad base of research leaders across career stages, areas and disciplines relevant to health; Develop and maintain Canadian capacity; Provide flexibility to pursue new, innovative lines of inquiry as part of an overall program of research; Contribute to the creation and use of health-related knowledge. The Foundation Scheme will have one competition a year.

A separate stream for New investigators New/early-career investigators are eligible to apply to the Foundation Scheme competition as a Program Leader. CIHR defines a new/early career investigator as: Researchers who at the Stage 1 application deadline are independent researchers and have held a maximum of 5 years of full-time independent research appointment New investigators will be assessed with other applicants in Stages 1 and 2. Reviewers will be asked to consider career stage when assessing the application against the specified criteria. At Stage 3, new/early-career investigators will be assessed and ranked against other new/early career investigators.

Who was successful in Stage 1 of the Foundation Scheme? CIHR invited 467 (34%) applicants to submit a Stage 2 application Anticipated that between 150-210 applications will be funded in the first Pilot Total Distribution of Applications Standard Deviation Consolidated Rank Invited to Stage 2 Not Invited to Stage 2 + + New Investigator Invited to Stage 2 New Investigator Not Invited to Stage 2

Pillar distribution for Stage 1 of the Foundation Scheme Distribution of Applications by Pillar Percent of Applications (%) Historical OOGP Data (% of Successful Applications) % of Submitted Applications % of Successful Applications Biomedical Clinical Health Systems/ Services Social/Cultural/ Environmental/ Population Health

How did New Investigators do in Stage 1 of the Foundation Scheme? The first Foundation Scheme competition received more applications from new/early career investigators than originally expected (41% of applications). Peer reviewers expressed some concern about their ability to rank new investigators. Almost 20% of applications (87 of 467) that were brought forward to Stage 2 were submitted by new investigators (comparable to what is typically seen in the OOGP; ~15%). CIHR is committed to a minimum of 15% of funded Foundation grants will be awarded to new investigators. Percent of Applications within Pillar (%) Distribution of Applications submitted by New/Early Career Investigators by Pillar Biomedical Clinical Health Systems/ Services % Submitted % Successful Social/Cultural/ Environmental/ Population Health

What are competition timelines for the Foundation Scheme? Decisions for the 2014 first Foundation Scheme pilot will occur in July 2015 Competition timelines for the 2015 2 nd Foundation Scheme pilot are: Registration Deadline July 27, 2015 Stage 1 Application Deadline September 15, 2015 Anticipated Stage 1 Notice of Decision December 1, 2015 Stage 2 Application Deadline February 5, 2016 Anticipated Stage 2 Notice of Decision May 16, 2016 Anticipated Stage 3 Notice of Decision July 15, 2016 Funding Start Date July 1, 2016 16

The Project Scheme The Project Scheme is designed to capture ideas with the greatest potential for important advances It is expected to: Support a diverse portfolio of health-related research and knowledge translation projects at any stage, from discovery to application, including commercialization; Promote relevant collaborations across disciplines, professions and sectors; Contribute to the creation and use of health-related knowledge. The Project Scheme will have two competitions per year

When is the Project Scheme being launched? Funding opportunity for the 2016 Project Scheme live pilot competition was posted in March 2015 to provide the community with time to prepare Key dates include: Registration Deadline January 18, 2016 Application Deadline March 1, 2016 Anticipated Stage 1 Notice of Decision May 16, 2016 Anticipated Stage 2 Notice of Decision July 15, 2016 Funding Start Date July 1, 2016 Project Scheme is designed to capture ideas with the greatest potential for important advances. 18

Project Scheme: Supporting Materials Resources available on the Reforms website: Funding opportunity Application requirements Project Biosketch CV Quick Reference Guide Project Co-Applicant CV Quick Reference Guide Qs and As Additional materials to be posted: ResearchNet application instructions Peer Reviewer manual Interpretation guidelines Training materials

Strategic Funding Changes to the OOGP do not affect strategic funding!

Strategic Funding: Research Priorities and Roadmap Signature Initiatives CIHR Research Priority Areas Enhance Patient-Oriented Care and Improve Clinical Results through Scientific and Technological Innovations Support a High-Quality, Accessible and Sustainable Health-Care System Reduce Health Inequities of Aboriginal Peoples and other Vulnerable Populations Prepare For and Respond To Existing and Emerging Threats to Health Promote Health and Reduce the Burden of Chronic Disease and Mental Illness Roadmap Signature Initiatives are now at varying stages of development and implementation: Evidence Informed Healthcare Renewal Canadian Epigenetics, Environment and Health Research Consortium Community Based Primary Health Care Personalized Medicine Pathways to Health Equity for Aboriginal Peoples Inflammation in Chronic Disease Strategy on Patient-Oriented Research: Networks and SUPPORT Units International Collaborative Research Strategy for Alzheimer s Disease Environments and Health Work and Health Integrated Health Services

CIHR Virtual Institutes Newsletters as sources of information

INMD Partners

Grant Writing: What won t change YOUR GOALS re: REVIEWERS CONCERNS 1. Get the panel excited about the project - the question is interesting/important/novel and this proposal is so terrific, it just has to be funded 2. Demonstrate that the project is built on a great foundation - progress/published work (yours/others) - preliminary data; feasibility of what is proposed 3. Convince the panel that you can do the work - your track record - your research team - resources available (environment) - how well you ve written your story in the grant

Tips for Success 1. Set up an Internal Peer Review Panel #1 thing to set up Key: try for 3 reviewers and have them meet with you They should critically assess the scientific content and presentation This gives experience in reviewing grants and fosters collegiality It always vastly improves your grant 2. Start writing early 3. Write daily 4. Do the Junk in the first month (but not only the junk)

More tips for success Ask Who s the audience? Give the BIG picture. Make the reader care. Don t drown the reader in detail (the reader doesn t want to know). State Why a study needs to be done Make it enjoyable for the reviewer! an order for grant writing: Level 1 Level 2 Level 3 Summary of Research Plan Research Plan ~1/2 the allotted pages Background/Preliminary Results ~1/2 the allotted pages Level 4 Significance

Tips for Success (cont d) Place yourself in a strong position Productivity (number and quality of papers) Number of other grants The independence issue Your research team: each member has a clearlystated and appropriate role and the expertise required

Thank you for your attention!! Questions regarding the Foundation and Project Scheme Competitions can be directed to: Roadmap-Plan.Strategique@cihr-irsc.gc.ca