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Application summary Please note that this sample form is used for three Humanities & Social Science funding schemes: Research Fellowships, University Awards, and Research Awards for Health Professionals, and therefore displays all questions across these schemes. The online system will display only the questions relevant to the award type for which you are applying. Type of award requested Application title Proposed duration of funding (months) Proposed start date Name of administering organisation Lead applicant's address at administering organisation Department/Division Organisation Street City/Town Postcode/Zipcode Country Research funding area Please select the research funding area for your application Lead applicant Lead applicant details Full Name Page 1 of 19

Department Division Organisation Address Line 1 City/Town Postcode Country Telephone No. Email Address ORCID id ORCID id Career history (current/most recent first) From To Position Organisation Source(s) of personal salary support Current/last appropriate salary details Salary grade Basic salary (per annum) Currency Date of last increment Education/training From To Qualification Subject Organisation The following questions are for Research Fellowship and Research Award for Health Professionals applicants only. All applicants should complete the final part of this section from Career breaks onwards. Do you have a PhD? Page 2 of 19

PhD examiners 1 Name Position Organisation Email address External examiner 1 Name Position Organisation Email address Clinical status Do you have a medical/veterinary degree? Please specify Are you clinically active? What is your specialty? Page 3 of 19

Please specify Career breaks Have you had any career breaks or periods of part-time work, for example parental or long-term sick leave? Please provide details Do you wish to undertake this award part time? Professional recognition Please list: (i) Prizes, honours and awards received during your career, including invited talks during the last three years; (ii) Current memberships of funding agency advisory and/or journal editorial boards. Career contributions What are your most important research-related contributions to date? These may include contributions to health policy or practice, or to technology or product discovery and development. (350 words max.) Personal statement Describe how this Award will further your research and career aspirations, and its context in your longer-term vision. (300 words max.) Page 4 of 19

Research environment What considerations led you to choose this research environment and sponsor for your research? If you have already been based in this research environment for a year or more, please specify your reasons for remaining. (400 words max.) Peer-reviewed publications and other research outputs List up to 20 of your most significant peer-reviewed publications, preprints, or other scholarly research outputs, e.g. patents, policy guidelines or briefings. You may provide a summary of your contribution to, or your role in, the work associated with each (e.g. intellectually conceiving or conducting the research, supervising staff, writing the paper). For original research publications please indicate those arising from Trust-funded grants in bold, and provide the PubMed Central ID (PMCID) reference for each of these. Please refer to guidance notes. Publications should be in chronological order with the most recent first. Please give citation in full, including title of paper and all authors*. Citations to preprints should state Preprint, the repository name and the articles persistent identifier (e.g DOI). (*All authors, unless more than 10, in which case please use et al, ensuring that your position as author remains clear.) Total number of peer-reviewed publications which you have authored/coauthored. Please exclude abstracts and literature reviews. Are you a named author on any Wellcome Trust funded original peer-reviewed research papers, published from October 2009 onwards? Are all your Wellcome Trust funded original peer-reviewed research papers, published from October 2009 onwards, compliant with our open access policy? Current and recent research funding (including Wellcome Trust grants) Please list all held in the last five years and any key prior grants (list the most recent first). State the name of the awarding body, name(s) of grantholder(s), title of project, amounts awarded, your role in the project, and start and end dates of support. For all active grants, indicate the number of hours per week that are spent on each project. Page 5 of 19

Current academic or professional reference Please upload your current academic or professional reference (500 words maximum). The remainder of this section is for Research Award for Health Professionals applicants only: Do you have a medical/veterinary degree? Are you a nurse or other health professional? Please specify Are you clinically active? What is your specialty? Please specify Please state the number of hours per week that will be spent on routine clinical work or that will be needed for further training requirements. What level of clinical contract do you currently hold? Please specify Name of Health Authority or Hospital Trust. Date current contract expires What progress, if any, has been made towards accreditation in your chosen specialty? Page 6 of 19

What level of honorary clinical contract will be sought during this award? Please specify Please give your General Medical Council (GMC) or your General Dental Council (GDC) number Do you hold a National Training Number (NTN)? When do you intend to apply for an NTN? In which postgraduate deanery is your NTN held, or will be held? Do you hold a Certificate of Completion of Training (CCT)? State date awarded What date would you expect to qualify to receive your CCT, assuming your Research Award application is successful? Are you a member of the Royal College of Veterinary Surgeons (RCVS)? Please indicate your time and experience spent in clinical practice (100 words max.) Do you hold a professional qualification? Page 7 of 19

Please state the number of hours per week that will be spent on routine clinical work or that will be needed for further training requirements. Qualification title Year awarded Are you training for a professional qualification? Qualification title At what stage of professional qualification and/or training are you, and when do you expect to qualify? Supervisors This section is for Research Fellowship and Research Award for Health Professionals applicants only. Prospective supervisors/research mentors 1 Prospective supervisor/research mentor Full Name Department Division Organisation Address Line 1 City/Town Postcode Country Telephone No. Email Address Career history (current/most recent first) Page 8 of 19

From To Position Organisation Source(s) of personal salary support Recent publications List no more than five publications that you consider the most important and relevant to this application. Publications should be in chronological order with the most recent first. Please give citation in full, including title of paper and all authors*. (*All authors, unless more than 10, in which case please use et al, ensuring that your position as author remains clear.) Current and recent research funding (including Wellcome Trust grants) Please list all held in the last five years and any key prior grants (list the most recent first). State the name of the awarding body, name(s) of grantholder(s), title of project, amounts awarded, your role in the project, and start and end dates of support. For all active grants, indicate the number of hours per week that are spent on each project. Track record in research mentorship and training How many fellows/students have you supervised over the past five years? Please give their name, the funder, the year of award and where the individual is now, including current post if known. Please also indicate how long the PhD took to obtain, explaining any anomalies if necessary. Supervision of Fellow/Research Award holder Please indicate the amount of time that you intend to spend supervising the Fellow/Research Award holder (hours per week). Indicate how you will fulfil your mentorship responsibilities. (300 words max.) Page 9 of 19

Recommendation Please upload your letter of recommendation (500 words maximum). Sponsors Sponsor 1 Sponsor Full Name Department Division Organisation Address Line 1 City/Town Postcode Country Telephone No. Email Address Title of current post Date of appointment Expected date of termination Source(s) of personal salary support Relationship of current application to other work in the sponsor's department (500 words max.) Page 10 of 19

Current and recent research funding (including Wellcome Trust grants) Please list all held in the last five years and any key prior grants (list the most recent first). State the name of the awarding body, name(s) of grantholder(s), title of project, amounts awarded, your role in the project, and start and end dates of support. For all active grants, indicate the number of hours per week that are spent on each project. The Recommendation is only required for University Award applicants Recommendation Please outline your support for the proposal, including a) how the applicant s work fits into the departmental or institutional strategy, b) how the applicant will be supported throughout their award, and c) confirmation that the offer of a permanent position will be upheld at the conclusion of the grant (500 words maximum). Collaborators Will you require any key collaborators for this proposal? Please list any key collaborators* (name and organisation) and provide a very brief outline of their role in the proposed research. *The collaborators named may be replaced with suitable alternatives should it be necessary or appropriate to do so. I confirm that the collaborators named above have agreed to be involved, as described, in the proposed research and are willing for their details to be included as part of this application. Related applications Page 11 of 19

Is this or a similar application for funding currently under consideration elsewhere? Please provide name(s) of funding organisation(s) and decision date(s) Is this a resubmission of an application submitted to the Wellcome Trust within the last 24 months? Please describe how this application differs from the original (200 words max.) Research summary Please provide a summary of your proposed research, including key goals (200 words max.) Archival research Will the research project require access to archives? Please provide a list of archives Page 12 of 19

Have the intended archives been catalogued? Is access guaranteed? Details of research project Detail (a) research focus and/or question(s) to be addressed, (b) why the idea is important, (c) work which has led up to the project, (d) methodology to be used, (e) plan of research including brief timetable and milestones, and (f) relevance of the project to scholarship, policy and/or practice. No more than 3,000 words should be used to describe the research project. Please note, this is an example structure. It is intended as a guide and is by no means prescriptive. (3000 words max.) You may submit up to two A4 pages of additional information (such as graphs, figures, tables and essential unpublished data). Bibliographical references You should give the citation in full, including title of paper and all authors, in alphabetical order, and include any primary sources to be consulted. Are there any papers listed in your 'References' section as being "in press" that you wish to submit to us? Upload papers "in press" Dissemination of research findings How do you intend to disseminate the findings and/or outputs of your research to the audience(s) you have identified? Please give details of those audiences. (250 words max.) Page 13 of 19

Data management and data sharing Will the proposed research generate data or software outputs that hold significant value as a resource for the wider research community? Please provide a data management and sharing plan (700 words max.) Public engagement Do you have plans for engaging with the non-academic public about your work? Do you wish to apply for a provision of funds for public engagement as part of your research proposal? Please refer to guidance for further information. Please provide a brief outline of your public engagement plans (250 words max.) Please note that we provide support for Wellcome Trust funded researchers to engage with the non-academic public. Do you wish to receive information about training, funding and other public engagement opportunities? Please note that we provide support for Wellcome Trust funded researchers to engage with the non-academic public. Do you wish to receive information about training, funding and other public engagement opportunities? Please provide details of your proposal This should include: Page 14 of 19

(i) the vision for your programme, including aims, target audiences, activities and outputs; (ii) public engagement experience of staff and external partners; (iii) how your programme will be monitored and evaluated, including success indicators; (iv) host organisation support for the programme; (v) a high-level budget breakdown. (850 words max.) Total amount requested Please refer to guidance for allowable costs Details of Wellcome Trust engaging science awards held and applied for by the applicant(s) over the last five years. Please include the name of grantholder(s), grant number (if known), the title of the project, the amount and period of award. Please also briefly describe any commissioned work funded by the Wellcome Trust. Location of activity Will the funded activity take place at more than one location? For each location, select the country and, where applicable, state the organisation (please include the administering organisation). Country Organisation Will the funds awarded be allocated to more than one location? For each location, please select the country, state the organisation and enter the value and currency of funds to be allocated. Please include the administering organisation. Country Organisation Value of funds Currency - Costs requested and justification Page 15 of 19

Please select the currency in which you wish to apply. Is the selected currency your local currency? What is your local currency? Please state clearly the reasons for requesting costs in the selected currency (100 words max.) Salaries Are you requesting salaries? Please refer to guidance notes and definition of terms for further details Salaries / Stipends Staff category Name (if known) Basic starting salary (p.a.) Salary grade / scale Period on project (months) % time Total Studentship fees Are you requesting studentship fees? Materials and consumables Are you requesting materials and consumables? Materials and consumables Description Total Equipment Are you requesting equipment? Equipment Page 16 of 19

Type of equipment No. of items Cost per item Cost of maintenance contract Contribution from other sources Total Travel and subsistence Are you requesting travel and subsistence? Travel and subsistence Description Total Miscellaneous costs Are you requesting miscellaneous costs? Miscellaneous other Type Description Total Are you requesting research management costs under the miscellaneous costs heading? (for applicants from low- and middle-income countries only) Please upload a letter from the Finance Director of the host organisation confirming that your request for research management costs is a true representation of the costs incurred. Justification for resources requested Please provide a complete justification for all the resources requested, ensuring that you present this information according to the cost headings requested above. (700 words max.) Full economic costing Is your organisation based in the UK? Is your organisation calculating the full economic cost of this proposal? Page 17 of 19

What is the total full economic cost ( )? Research involving human participants, human biological material and identifiable data Does your project involve human participants, human biological material, or identifiable/potentially identifiable data? Please confirm that you have read the Trust s guidance on the feedback of health-related findings in research and that you are in the process of considering your approach to this. Please state by whom and when the ethics of the project has been, or will be, reviewed and specify any other regulatory approvals that have been obtained, or will be sought. We reserve the right to see relevant approval documents at any point during the lifetime of the grant, in accordance with our policy position on research involving human participants. In the course of your project, do you propose to use facilities within the National Health Service (NHS) or to involve patients being cared for by the NHS? Is a formal sponsor required for the project, for example under the Medicines for Human Use (Clinical Trials) Regulations or the Research Governance Framework for Health and Social Care and equivalent guidance? Please indicate which organisation(s) has/have agreed to fulfil this role. Please note that the Wellcome Trust cannot act as sponsor. Risks of research misuse Please confirm that you have considered whether your proposed research could generate outcomes that could be misused for harmful purposes. Page 18 of 19

Have you identified any tangible risks of this type? Please briefly describe these risks and the steps that you and your organisation will take to manage them (250 words max.) Freedom to operate/conflicts of interest Describe any freedom to operate issues or potential conflicts of interest that have been identified or that might arise and how these will be or have been addressed. In particular, please consider the following: Do any of the individuals involved in the project hold any consultancies or equities in, or directorships of, companies or other organisations that might have an interest in the results of the proposed research? Will the proposed research use technology, materials or other inventions that are subject to any patents or other form of intellectual property protection? Will any element of the research be subject to agreements with commercial, academic or other organisations, including arrangements with collaborators named in the grant application, that might lead to intellectual property issues or restrictions? (350 words max.) Wellcome Trust supported facilities Will the project be based in one of the following Wellcome Trust supported facilities: the Wellcome Trust Sanger Institute a Wellcome Trust Centre a Major Overseas Programme the Francis Crick Institute? Please specify Page 19 of 19