Reducing preventable maternal, newborn, and child deaths at scale by improving care effectiveness and efficiency

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ASSIST Legacy Webinar Series Strengthening Health Systems to Achieve Better Outcomes Reducing preventable maternal, newborn, and child deaths at scale by improving care effectiveness and efficiency July 25, 2018 The webinar will begin momentarily; during the webinar, please type your questions for the speakers in the Chat box. 1

Reducing preventable maternal, newborn, and child deaths at scale by improving care effectiveness and efficiency Webinar Moderator Lynne Miller Franco Vice President, Technical Assistance and Evaluation EnCompass LLC 2

Today s speakers Nigel Livesley Regional Director for South Asia USAID ASSIST Project, URC Tamar Chitashvili Senior Quality Improvement Advisor for MNCH, USAID ASSIST Project, URC Troy Jacobs Senior Medical Advisor, Office of Maternal Child Health and Nutrition, USAID 3

Reducing preventable maternal, newborn, and child deaths at scale in India Nigel Livesley MD, MPH Regional Director USAID ASSIST Project University Research Co., LLC 4

Improving care effectiveness and efficiency To reduce preventable deaths At scale 5

Improving care efficiency and effectiveness To reduce preventable deaths At scale 30% of health care resources are wasted 6

Assessing women for complications after delivery 7

0.16% of women were identified with complications 8

Women with complications are now 12 times more likely to be identified early New system of care Observation room 9

Sustained improvement and NO MATERNAL DEATHS in post partum ward 9 3.0% 8 7 number of times women were assessed in first 6 hours 2.5% 6 2.0% 5 4 3 2 1 % of women identified with complications and managed appropriately 1.5% 1.0% 0.5% 0 Jan Feb March April May June July Aug Sept Oct 0.0% 10

What can be scaled up? The specific change? 11

What can be scaled up? The specific change? - What level of detail? - Use the room to the right of the nurses station as an observation room and put all equipment in the SW corner of the room - Organize things efficiently 12

What can be scaled up? The specific change? - What level of detail? - Use the room to the right of the nurses station as an observation room and put all equipment in the SW corner of the room - Organize things efficiently - What if inefficiency in finding women and equipment is not the main problem? - Assessment may be poor because at lack of equipment or lack of skills. 13

What can be scaled up? The general method to diagnose and fix unit level problems 14

What can be scaled up? The general method to diagnose and fix unit level problems How to prioritize improvement goals How to work in a multi-disciplinary team How to use different tools to diagnose problems How to develop possible solutions How to adjust these solutions to work in a specific setting 15

Only 27% of newborns admitted to NICU had a normal temperature (73% were cold) 100.00% Percentage (%) of babies admitted to the NICU with normothermia 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% 0.00% 1 Jul 1 Aug 1 Sep 1 Oct 1 Nov 1 Dec 1 Jan 1 Feb 1 Mar 1 Apr 16

Only 27% of newborns admitted to NICU had a normal temperature (73% were cold) Percentage (%) of babies admitted to the NICU with normothermia 100.00% 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% Changes: Installing thermometer in labor rooms to encourage staff to increase ambient temperature Keeping a supply of pre-warmed linen to receive the baby Tell orderlies to keep battery in transport incubator charged 17 0.00% 1-Jul 1-Aug 1-Sep 1-Oct 1-Nov 1-Dec 1-Jan 1-Feb 1-Mar 1-Apr

Improvement but sustainability is questionable? 100.00% Percentage (%) of babies admitted to the NICU with normothermia 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% 0.00% 1-Jul 1-Aug 1-Sep 1-Oct 1-Nov 1-Dec 1-Jan 1-Feb 1-Mar 1-Apr 18

Make it easier to keep the transport incubator batteries charged Percentage (%) of babies admitted to the NICU with normothermia 100.00% 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% Changes Tape charger leads to incubator Set up dedicated charging stations around the hospital 0.00% 1-Jul 1-Aug 1-Sep 1-Oct 1-Nov 1-Dec 1-Jan 1-Feb 1-Mar 1-Apr 19

Improvement, but batteries are old and no longer holding a charge Percentage (%) of babies admitted to the NICU with normothermia 100.00% 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% Changes Get new batteries for transport incubator Transport baby with pre-warmed linen as redundancy 0.00% 1-Jul 1-Aug 1-Sep 1-Oct 1-Nov 1-Dec 1-Jan 1-Feb 1-Mar 1-Apr 20

Continued improvement 100.00% Percentage (%) of babies admitted to the NICU with normothermia 90.00% 80.00% 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% 0.00% 1-Jul 1-Aug 1-Sep 1-Oct 1-Nov 1-Dec 1-Jan 1-Feb 1-Mar 1-Apr 21

More warm babies 22

was associated with fewer deaths 23

39% reduction in all cause mortality (c-chart) 12.0 10.0 8.0 6.0 4.0 2.0 0.0 Dec Feb Apr Jun Aug Oct Dec Feb Apr Cbar UL deaths 24

39% reduction in all cause mortality 85 more babies per year survive 25

39% reduction in all cause mortality 85 lives saved per year Equivalent to ELIMINATING infant deaths in Vermont plus Rhode Island plus 20% of Wyoming 26

What can be scaled up? The specific change? - What if problems with keeping the incubator charged are not the main problem? 27

What can be scaled up? The general method to diagnose and fix unit level problems How to prioritize improvement goals How to work in a multi-disciplinary team How to use different tools to diagnose problems How to develop possible solutions How to adjust these solutions to work in a specific setting 28

Improved standard of health 29

Improved standard of health Improved interaction between provider and patient 30

Improved standard of health Improved interaction between provider and patient Correct resources Correct clinical skills Good organization of care 31

Scaling up new ideas Organization New ideas 32

Scaling up new ideas Organization People believe they have freedom to try new things Communication between different parts of the organization are good There are administrative resources to support adaptation of new ideas 33

Scaling up new ideas New idea Relative advantage Compatible Simple Adaptable Organization People believe they have freedom to try new things Communication between different parts of the organization are good There are administrative resources to support adaptation of new ideas 34

Scaling up new ideas QI methods Indian healthcare organizations 35

Relative advantage Compatibility Simplicity Adaptability Focus on outcomes Show results Highlight successes in fixing problems that resource provision and clinical training cannot fix Work with individuals and organizations who do see this approach as compatible Remove jargon Start with fundamentals presented in practical ways Avoid standardization Encourage adaptation at all levels 36

Organizations All India Institute for Medical Sciences Partnership with WHO SEARO Point of Care Quality Improvement Training materials Coaching training Program management guide Supporting QI programs in various states and nearby countries www.pocqi.org 37

Organizations Nationwide Quality of Care Network Doctors and nurses from academia and private sector Supporting QI programs in various states Often in partnership with private sector and professional organizations http://www.qoc.net.in/ 38

ASSIST India 27 districts in 6 states 32 million catchment population 435 QI teams ~ 15 000 deliveries per month 39

Reduced perinatal mortality in supported sites 3.00% 2.50% 2.00% 1.50% 1.00% 0.50% 0.00% Jul-13 Oct-13 Jan-14 Apr-14 Jul-14 Oct-14 Jan-15 Apr-15 Jul-15 Oct-15 40

Perinatal deaths/1000 births Jul-Nov 2013-2015 41

Reducing preventable maternal, newborn, and child deaths by improving care effectiveness and efficiency Tamar Chitashvili MD Senior Quality Improvement Advisor for MNCH USAID ASSIST Project University Research Co., LLC 42

ASSIST activities at global level to improve quality of care (QoC) in MNCH Global QI initiatives and TWGs Participating in Implementation and Monitoring TWGs of the WHO-led Quality of Care Network Prioritization and field testing of pediatric QoC measures Sick Inpatient Newborn Care Situational Analysis Contribute to global learning in the field of improvement Develop and implement tools/approaches to assess and improve QoC Generate new knowledge to increase the effectiveness and efficiency of applications of improvement science in LMICs 43

Illustrative QI activities at different levels in Uganda 2 nd HSQISF 3 Annual National QI conferences 1. HCWs QI Manual 44 1 National QI reporting Format

Illustrative activities: Establishing MPDSR structures, processes and guidelines across all levels in Uganda Sr. Susan Akwanga, MPDSR focal person Anaka Hospital, Nwoya district : MPDSR saves lives, I ve have seen it work and I call upon my colleagues to embrace it. 45 Developed Maternal and Perinatal Death Surveillance and Response (MPDSR) guidelines Revised maternal death audit forms Set up MPDSR structures: focal person in every facility and district. Support Implementation Schedules for MPDSR meetings (facility and district levels). MPD review by facility teams and coaches Action plan and follow up to address gaps Presentation/discussion the work at district quarterly MPDSR meetings

Lessons Learned QI enables teams to find innovative local solutions and address gaps with existing resources 46

QI enables teams to address gaps with existing resources Results of direct observation of pediatric outpatient visits in intervention facilities in Uganda Indicators Baseline N=212 Endline N=293 0% 45% Children assessed for 3 general danger signs Assessment of three main symptoms Temperature measured Weight measured 22% 33% 21% 93% 97% 100% 47 GAPS IN ESSENTIAL SEVERITY ASSESSMENT PRACTICES Limited availability of scales and thermometers Limited time of care providers CHANGES MADE BY QI TEAMS TO CLOSE THE GAPS Establishing the triage places for sick children Involve village health workers in assessment of vital and danger signs

Better documentation and data quality essential to inform continuous QI Baseline % 0 Assessment of Nutrition status Assessment of % 82 Current 0 0 Vaccination status Assessment of Vital signs 72 60 0 Assessment of Danger signs 56 Improved assessment and documentation of children at OPD in Northern Uganda 48

Embedding M&E in improvement design is critical for learning 100% 90% 80% 70% Percentage of children 2mo 5yrs with documented assessment of nutritional status in 10 facilities in Uganda, July, 2015 March 2017 Improvement in intervention sites compared to control sites +63%, P < 0.0001 83% 100% 90% 80% 70% % of children under 5yrs with vaccination status documented in OPD in 10 facilities in Uganda, July, 2015 March, 2017 Improvement in intervention sites compared to control sites +80%, P < 0.0001 80% 60% 60% 50% 40% 30% 20% 10% 0% 0% J 15 S 15 N 15 J 16 M 16 M 16 J 16 S 16 N 16 J 17 M 17 Denominator = 300 per month based on random sample of 30 records per facility 50% 40% 30% 20% 10% 0% 0% J 15 S 15 N 15 J 16 M 16 M 16 J 16 S 16 N 16 J 17 M 17 Denominator = 300 per month based on random sample of 30 records per facility Results of routine monitoring compared with evaluation of effectiveness of IMNCI improvement intervention in Northern Uganda 49

Documenting and sharing learning across teams allows rapid scale-up of improvement 50

Improving MNCH processes scale: Saving Mothers Giving Life (SMGL) in Uganda 51

Measurable impact on perinatal outcomes at scale: illustrative results from Uganda and Mali Indicators Perinatal mortality rate/ 1000 birth Pre-discharge neonatal mortality/1000 LB Neonatal Case Fatality- Newborn Asphyxia Institutional maternal mortality ratio/ 100,000 deliveries % change Country, Scale, Timeline -25% Uganda, 9 districts, Jan Jan 16-Jan 16-17 17-25% Uganda, 7 districts, Dec Dec 14-Dec 14-1616 -26% Uganda, 9 districts, Jan 16-Jan 17-30% Uganda, 7 districts, Dec 14-Dec16-73% Mali, 4 regions, 206 sites, Nov16-Aug 17-21% Uganda, 7 districts, Dec Dec 14-Dec16 14-16 -21% Uganda, 9 districts, Jan16-Jan17 Jan 16-17 -52% Mali, 4 regions/306 sites, Dec16-Jun 17 Case Fatality-PPH -71% Mali, 4 regions/306 sites, Dec16-Jun 17 52

QI can be effective in improving not only care effectiveness but also access to lifesaving services and medications 53

Rationalized prescription practices for treatment of common childhood conditions, Uganda 100% % of children 2mo 5yrs with pneumonia to whom first line antibiotic was prescribed 10 sites, n=300 % of children 2 mo 5yrs with a classification of cough or cold to whom an antibiotics is prescribed % of children 2mo under 5 years with malaria, treated with concurrent unjustified antibiotics therapy % of children under 5yrs with a diagnosis of diarrhea, where antibiotics or other non EB treatment is prescribed 80% Antibiotic for cough or cold 60% 1st line antibiotic for pneumonia Antiobiotics for malaria 40% Non EB treatment for diarrhea 20% 0% Jul 15 Aug 15 Sep 15 Oct 15 Nov 15 Dec 15 Jan 16 Feb 16 Mar 16 Apr 16 May 16 Jun 16 Jul 16 Aug 16 Sep 16 Oct 16 Nov 16 Dec 16 54

Improved access to essential medications though rational antibiotic use 12.0 10.0 8.0 Average number of stock-out days (no Cotrimoxazole of any dose 120mg, 240mg, or 480mg) per month in 9 facilities in Northern Uganda Intervention begins Non EB use of Cotrimoxazole reduced across all common childhood conditions. Attributable improvement (P<0.0001 for all results): 1) cough or cold: -42% 2) Pneumonia -23%, 3) Malaria -26% 4) Diarroea -35% 6.0 4.0 Baseline median = 3.7 days 2.0 0.0 Shift of six points below the median Sep-15 Oct-15 Nov-15 Dec-15 Jan-16 Feb-16 Mar-16 Apr-16 May-16 Jun-16 Jul-16 Aug-16 Sep-16 Oct-16 Nov-16 Dec-16 Jan-17 Feb-17 55 Baseline period

Improved access to lifesaving services: outpatient treatment of young infants with PSBI 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Evidence-based treatment of young infants with possible severe bacterial infection (PSBI) 0% 20% 0% 6% +68% improvement attributable to QI, P<0.0001 Intervention Baseline Control Baseline Intervention Endline Control Endline 63% 32% 0% 13% Full outpatient treatment for those patients who can not access referral Initial treatment and referral 56

Improved equitable access to health services: Reducing gender gap in infant vaccination in Mali 44 sites, 2 districts of Mopti Region (Dec 2016-Jun 2017) 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 1200 900 600 300 0 0% 57 41% 18% Complete immunization schedule for girls enrolled in the immunization program Complete immunization schedule for boys enrolled in the immunization program 23% Oct 16 Nov 16 Dec 16 Jan 17 Feb 17 Mar 17 Apr 17 May 17 Number of girls <1year Number of boys <1year First coaching visit Oct 16 Nov 16 Dec 16 Jan 17 Feb 17 Mar 17 Apr 17 May 17 11% 76% 65%

QI is not a luxury: it can save the cost of care Economic evaluation of child care improvement interventions in Georgia and Uganda Country Georgia Clinical conditions Respiratory tract infection (RTI) at ambulatory level Pneumonia at # of patients Total cost of project in USD incremental cost-saving per patient Total incremental cost saving in USD 26236 22,484 4.9 127,802 1544 14,989 12.1 18,614 hospital level Subtotal 37,473 146,416 Uganda Cough/ cold/rti 45,621 2,146 0.13 5820 Pneumonia 10,841 2146 0.03 302 Malaria 120,768 2,146 0.02 3006 Diarrhea 16,502 2,146 0.05 823 Subtotal 8,584 9,951 58

QI is the critical path to reach effective universal health coverage Without quality health services, UHC can remain an empty promise. 59

Commentary and Discussion Lynne Franco EnCompass Troy Jacobs USAID Nigel Livesley URC Tamar Chitashvili URC Participants should use the chat function to post questions (send to All panelists ). Responses to questions not addressed during the webinar will be posted afterwards on the ASSIST website. 60

Closing Remarks Lynne Miller Franco Vice President, Technical Assistance and Evaluation EnCompass LLC 61

Resources to learn more: https://www.usaidassist.org/content/legacy-webinar-series-reducingpreventable-maternal-newborn-and-child-deaths 62

ASSIST Legacy Webinar Series Strengthening Health Systems to Achieve Better Outcomes Upcoming webinar: Leading health care improvement: What leaders need to know to act. Lessons from East and West Africa Wednesday, September 12, 2018 9:00-10:00am Register at: https://zoom.us/webinar/register/wn_da99ng27sj6uamgudwd-pw 63