Strategic Planning and Septic Shock: What Code blues and Cardiac arrest can t tell you about your MET

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Strategic Planning and Septic Shock: What Code blues and Cardiac arrest can t tell you about your MET J Gilleland MD, FRCP(C) Assistant Professor, Department of Pediatrics Division of Pediatric Critical Care McMaster Children's Hospital Hamilton, Ontario, Canada

Approaches to Planning Contextual Long-range Strategic Proactive, focus on values, mission, organizational culture, themes and visions Responsive, works within mission/directive, focus on specific goals, objectives Adaptive, focus on program and resource allocation, review and improvement

Contextual Strategic Mission Statement Longrange Evaluation Performance indicators Research Goals Objectives Plan / Budget Implementation

Rapid Response Structure * Adapted from Baldisseri, 2006 MET conference proceedings Afferent arm Efferent arm Case detection Trigger Evolving critical illness MET Response Patient stabilization Controlled escalation of care -Code blue -PCCU admit -OR Data collection, evaluation, strategic planning Education Patient safety issues

Processes that influence strategy 1) Individual cognitive processes A project lead s understanding of particular issues 2) Social and organizational processes Existing policies and procedures, labour issues, staff turnover, job satisfaction 3) Political processes that may shift power to influence purpose and resources Funding

PMET: Closing the loop Have we met our goals and objectives? Are the results consistent with our mission? Are their new processes at work that require adaptation of our current strategy? Can we do better even in the face of success? How can future resource needs be prioritized?

PMET Performance Indicators Current currency of success for a MET Decreased mortality rates Decreased codes Decreased cardiac arrests Indicators of global team functioning Difficult to attribute benefit to a specific area of the RRS structure Difficult to monitor in real time

5 4 3 2 1 Code Blue Activations at McMaster Children s Hospital 0 Apr Jul Oct Jan-06 Apr Jul Oct Jan-07 Apr Jul Oct Jan-08 Apr Jul Oct 9-Jan Oct Jan-05 Month / Year Introduction of PMET Jul Apr Jan-04

PCCU Mortality

Questions How to differentiate and evaluate afferent and efferent effects of the team? Can we measure if the team is improving the quality of health care delivery in an objective way?

What to target?

Adherence to best practice guidelines for septic shock Well known, international guidelines for septic shock High mortality if untreated Significantly improved survival associated with adherence to best practice guidelines 25 % of patients triggering PMET for sepsis /infection Can assess response times as well as therapeutic endpoints

Onset of Septic Shock 1 st fluid bolus PCCU or PMET consult Hospital Admission time PCCU Admission

Results Patients admitted to PCCU with septic shock identified from PCCU and PMET databases and PCCU logbooks n = 36 Pre PMET n = 21 Post PMET n = 15 Excluded if not admitted from a PMET Zone: ED, OR, other institution PMET called in 87% Deaths n = 8 (38%) Survivors n = 13 Deaths n = 4 (27%) Survivors n = 11

Onset of shock to PMET / PCCU consult Total Pre- PMET Post-PMET Mean (SD) 11.0 (-7.1 29.1) Median (IQR) 3.6 (2.0 8.0) Survivors 9.7 (-10.4 29.8) 1.6 (0.0 9.6) Median (IQR) 2.4 (1.7 4.3) 3.6 (0.4 9.9) Deaths Median (IQR) 23.6 (4.9 30.7) -0.1 (-0.2 2.6) *p = 0.009 NS

Onset of shock to first fluid bolus Total Pre- PMET Post-PMET Mean (SD) Median (IQR) 8.5 (-7.5 24.5) 2.5 (0.6 5.1) 5.5 (-11.1 22.1) 0.0 (-0.7 2.8) Survivors Median (IQR) 1.9 (0.3 2.9) 0.0 (-1.0 0.5) Deaths Median (IQR) 13.6 (1.8 28.7) 4.1 (0.0 9.2) *p = 0.026 NS

Volume of fluid within 1 hour of shock diagnosis Total Pre- PMET Post-PMET Mean (SD) Median (IQR) 18.7 (8.8 28.6) 19.3 (11.1 21.9) 26.9 (5.9 47.9) 21.0 (20.0 35.8) Survivors Median (IQR) 19.7 (15.4 21.1) 21.0 (20.0-40.0) Deaths Median (IQR) 14.0 (11.1 21.9) 22.5 (17.5 26.6) NS NS

Conclusions Improved response times between survivors and non-survivors of septic shock suggests institutional culture change and acceptance of PMET Patients admitted to PCCU for septic shock still under-resuscitated: why?

Consider these activation criteria: 11 year-old

PMET Activation Criteria *Adapted from Tibballs, et al. Arch Dis. Child. 2005:90; 1148-1152

PMET trigger Vs.Goldstein, et al: 11 year old PMET Criteria (Tibballs, et al) HR > 140 SBP < 80 Goldstein HR > 130 SBP < 105

Back to the mission PMET designed to prevent code blue and cardiac arrest not for early detection of evolving illness Patients may have very abnormal vital signs without meeting activation criteria thresholds

Where to invest future resources? Afferent arm Efferent arm Case detection Trigger Evolving critical illness MET Response Patient stabilization Controlled escalation of care -Code blue -PCCU admit -OR Data collection, evaluation, strategic planning Education Patient safety issues

Discussion High thresholds for PMET activation require frontline staff to recognize septic shock and need for early aggressive fluid resuscitation and initiation of antibiotics Increase focus on afferent case detection, knowledge translation of best practice guidelines and importance of early and aggressive therapy for septic shock

Intervention Multidisciplinary PMET rounds Brown-bag noon-hour sessions for frontline staff Development of an intranet website to post presentations and guidelines for access by educators and staff working off hours Review of afferent triggers: PEWS?

References Presley, M.W. Leslie, D.W. Understanding Strategy: An Assessment of Theory and Practice. Higher Education Handbook of Theory and Practice, Vol 14, 1999, Agathon Press Peterson, M.W. Using Contextual Planning to Transform Institutions, Planning and Management for a Changing Environment, 1997. Jossey-Bass Publishers Inc. Lang, Daniel. Lecture: Mission based planning. Project planning and management course. University of Toronto, Department of Continuing Medical Education. October 12, 2007. Carcillo, JA, et al. Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Patients in Septic Shock. Crit Care Med. 2002; 30: 1365-1378 Han, YY, et al. Early Reversal of Pediatric-Neonatal Septic Shock by Community Physicians is Associated with Improved Outcome. Pediatrics. 2003; 112: 793-799 Goldstein, B, et al. International Pediatric Sepsis Consensus Conference: Definitions for Sepsis and Organ Dysfunction in Pediatrics. Pediatr Crit Care Med. 2005; 6: 2-8 Tibballs, J, et al. Reduction of paediatric in-patient cardiac arrest and death with a medical emergency team: preliminary results. Arch Dis Child. 2005; 90; 1148-1152

Thank you Acknowledgments: Jennifer Watson, RN, BSc.N, CNCCP PCCU Clinical Leader Wendy Seidltiz, RN, BSc.N, MSc., Data Management Specialist