18 th Annual St. Louis Critical Care Update Advances in the Management of the Critically Ill Patient

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1 18 th Annual St. Louis Critical Care Update Advances in the Management of the Critically Ill Patient Saturday, September 9, 2017 St. Louis College of Pharmacy Academic Research Building St. Louis, Missouri Course Chair Presented By The Division of Pulmonary & Critical Care Medicine at Credit Provided By Continuing Medical Education

2 8:00am Registration & Continental Breakfast 8:20 Introduction & Welcome 8:30 How Do We Stop Bleeding in Patients Receiving Anticoagulants/Antiplatelet Drugs? Scott T. Micek, PharmD, BCPS 9:00 Should I Be Worried About Zika Virus, Bird Flu Virus, Dengue Virus and Chikungunya Fever? Steven J. Lawrence, MD, MSc 9:30 How to Use Ultrasound in the Initial Evaluation of Respiratory Failure Warren Isakow, MD 10:00 Refreshment Break 10:15 Acute Kidney Injury in the ICU, is it Preventable? Anitha Vijayan, MD, FASN 10:45 An Update on the Management of Septic Shock 11:15 When Should I Consider Use of Plasmapharesis in the ICU? Vladimir N.Despotovic, MD 11:45 Ketamine and Dexmedetomidin, How and When Do I Use these Agents in the ICU? Paul Juang, PharmD, BCPS 12:15pm Adjourn AGENDA Question & Answer session to follow each lecture.

3 ACCREDITATION In support of improving patient care, Washington University School of Medicine in St. Louis is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. AMA designates this live activity for a maximum of 3.5 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. ANCC (American Nurses Credentialing Center) designates this live activity for a maximum of 3.5 contact hours. ACPE (Accreditation Council for Pharmacy Education) ACPE credit will be awarded for this activity. Disclosure Policy It is the policy of, Continuing Medical Education, that planners, faculty and other persons who may influence content of this CME activity disclose all relevant financial relationships with commercial interests in order for CME staff to identify and resolve any potential conflicts of interest prior to the educational activity. Faculty must also disclose any planned discussion of unlabeled/unapproved uses of drugs or devices during their presentation. Detailed disclosures will be made in activity handout materials. Funding This activity is supported in part by various commercial organizations. A complete list of commercial supporters and contributors will be available at the time of the conference. Some companies may also exhibit.

4 ACTIVITY FACULTY Vladimir N. Despotovic, MD Assistant Professor of Medicine Division of Pulmonary and Critical Care Medicine Warren Isakow, MD Associate Professor of Medicine Division of Pulmonary and Critical Care Medicine Medical Director, Medical Intensive Care Unit Steven J. Lawrence, MD, MSc Associate Professor of Medicine Division of Pulmonary and Critical Care Medicine Paul Juang, PharmD, BCPS Associate Professor of Pharmacy Practice St. Louis College of Pharmacy Professor of Medicine Division of Pulmonary and Critical Care Medicine Director, Medical Critical Care, Barnes-Jewish Hospital Scott T. Micek, PharmD, BCPS Associate Professor of Pharmacy Practice St. Louis College of Pharmacy Anitha Vijayan, MD, FASN Professor of Medicine Division of Nephrology Medical Director, Acute Dialysis Unit, Barnes-Jewish Hospital Planning Committee Paul Juang, PharmD, BCPS Donna Prentice, RN, AMSN(R), ACNS-BC, Clinical Nurse Specialist Barnes Jewish Hospital, St Louis, MO

5 LEARNING AND PERFORMANCE OBJECTIVES An increasing number of studies have demonstrated that outcomes with new diagnostics and therapeutics applied in critically ill patients in regards to sedation, renal replacement therapy and ultrasonography, this course will review the research results. It has become imperative to update clinicians on these and other advances in critical care medicine. Multiple organ failure can be improved if evidence-based practices are followed; moreover, updated guidelines from the Society of Critical Care Medicine, the American College of Chest Physicians, the American Thoracic Society and the Infectious Diseases Society of America have been published to help direct clinical practices in this important population. This course is designed for critical care specialists, pulmonologists, general surgeons, anesthesiologists, hospitalists, internists, family practice and emergency medicine physicians, as well as, pharmacists, physician assistants, nurse practitioners, and nurses in these fields. The intended result of this live activity is increased knowledge, competence and performance in the delivery of critical care to adult patient. After completion of this seminar the participant should be able to: List factors contributing to poor outcomes in patients admitted to the intensive care unit setting. Prioritize the management and interventions for adults with serious infections, renal injury, and respiratory failure requiring intensive care unit admission. Analyze the risks and benefits underlying perioperative management of antiplatelet and anticoagulant medications. Describe the etiology and spread of the Zika virus. Identify symptoms that may be present in patients infected with the Zika virus and how often they appear. Discuss key concepts related to the transmission, symptoms, diagnosis, and treatment of Bird FluVirus, Dengue Virus and Chikungunya Fever. Identify the importance of kidney health on clinical outcomes. Define severe sepsis and septic shock. Describe initial management of severe sepsis and septic shock. Review current clinical indications for therapeutic plasmapheresis, photopheresis and other cytapheresis procedures. Discuss options for vascular access, anticoagulation, and prescription for the various apheresis techniques and their associated complications. Review the pharmacology and neuropharmacology of dexmedetomidine. Recognize the indications and available evidence for ketamine administration in the critical care setting. Assess when stress dose steroids are indicated and manage other endocrine medications in the perioperative period. Utilize ultrasound to assist with diagnosis of common conditions and facilitate common bedside procedures and to optimize cardiac function.

6 GENERAL INFORMATION Location: St. Louis College of Pharmacy, Academic Research Building, Room 111, 4588 Parkview Place, St. Louis, MO Since meeting room temperatures are difficult to regulate to everyone's appeal, bringing a jacket or sweater is recommended. Parking: Courtesy parking for paid registrants at the BJH North Garage only (Forest Park Pkwy to Euclid Ave., 224 S. Euclid Ave.). Validation for other medical center parking garages is not available. Overnight parking cannot be validated. Hotel Accommodations: To receive special rates when available, please indicate that you are attending a Washington University activity. The Parkway Hotel [on the medical center campus] (314) toll free (866) Forest Park Avenue, St. Louis, MO Transportation/MetroLink: The Central West End MetroLink Station is conveniently located at the medical center on Euclid Ave, 1½ block south of STLCOP, one block from The Parkway Hotel. The MetroLink trip from the station at the airport to the medical center takes approximately 20 minutes and costs $5.00 ( Taxis from the airport cost approximately $45. Please Note: Washington University is not responsible for airline, hotel reservations, or any other travel expenses. Please confirm registration acceptance prior to purchase of non-refundable or penalty airline tickets. Cancellations: Seminar registration fee less $25 administrative charge is refundable if cancellation is received in writing by September 4, Special Needs: Continuing Medical Education at Washington University School of Medicine fully complies with the legal requirements of the Americans with Disabilities Act rules and regulations thereof. If any participant of this meeting is in need of accommodations, please submit written requests at least one month prior to seminar date. Day of Seminar Only Telephone Number: (314) Callers should ask for the Washington University Critical Care seminar. For Further Seminar Information Continuing Medical Education, Washington University School of Medicine (314) (800) Fax (314) CME@wustl.edu Website: cme.wustl.edu Minimum and Maximum Enrollments Have Been Established.

7 REGISTRATION 18th Annual St. Louis Critical Care Update Saturday, Septmeber 9, 2017 To ensure proper spelling of your name, please print clearly. First Name Initial Last Name Degree Address City/ State/ Zip Office Phone Fax (required) Specialty: REGISTRATION FEES By Sep 1 After Sep 1 $95 $120 Fees include enrollment, continuing education credits (AMA, ANCC and ACPE) educational materials, continental breakfast, and North Garage parking. Ways to Register ONLINE Secure online registration available at: Will receive immediate payment confirmation via . MAIL this completed form with your check payable to Washington University CSRB 2214, CB S Euclid Ave. St. Louis, MO Registration/Payment Policy: Your full payment in advance completes your registration and ensures your enrollment in this course. Opportunities for on-site registration are limited and may be unavailable. To inquire about the availability to register on-site, please contact the CME office.

8 CONTINUING MEDICAL EDUCATION CSRB 2214, CB South Euclid Ave St. Louis, Missouri Critical Care Update September 9, 2017 More CME credit available ONLINE at Visit our website for other CME activities:

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