GSA Strategic Goals

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2 GSA Strategic Goals WHA/WHO: WSD needs to be mandated by a resolution on sepsis of the WHA/WHO 2. World Health Organization (WHO): Acknowledging that sepsis is the most common pathway to death following an infection 3. Raising public awareness and stimulate QI initiatives: Improve the knowledge on prevention and early signs of sepsisz 4. Global Burden of Disease Report (GBDR): Adequate recognition of the burden of sepsis 5. Adequate coding of sepsis in the WHO ICD-coding system: To achieve adequate representation of sepsis in the global and national disease reports

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4 The majority of poeple have not heard the term sepsis in 2013

5 Increase in Sepsis Awareness

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8 Report by the National Confidential Enquiry into Patient Outcome and Death 2015 in UK

9 Between percent of patients admitted to hospitals in the UK are diagnosed and treated too late National Confidential Enquiry into Patient Outcome and Death (2015)

10 Antimicrobials were delayed in 44% of patients National Confidential Enquiry into Patient Outcome and Death (2015) National Confidential Enquiry into Patient Outcome and Death (2015)

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13 CDC Launches Report & Awareness Initiative

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15 SEPSIS KILLS program: reduce preventable harm to patients with sepsis RECOGNISE: Risk factors, signs and symptoms of sepsis and inform senior clinician RESUSCITATE: With rapid antibiotics and IV fluids within one hour REFER: To specialist care and initiate retrieval if needed

16 Development of Sepsis Mortality Australia: from 35% to 18.5% England: from 45.5% to 32.1% USA: from 37 % to 29% Germany: from 47,8% to 43,6%

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18 Dec 2012 Sep 2013 Sep 2014 Sep 2015 Sep 2016 Hospital & Health Care Services 1,237 2,600 3,053 3,286 3,651 Non-Profit Organizations Health Care Professionals 1,529 1,478 2,071 2,214 2,417 Private Individuals ,092 1,256 Total 2,959 4,835 6,348 6,912 7,667

19 Dec 2012 Sep 2013 Sep 2014 Sep 2015 Sep 2016 Facebook 1,387 2,523 3,834 5,200 7,873 Twitter 422 1,048 1,976 3,225 4,676 Instagram

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25 Global estimates of hospital treated sepsis cases/year 30.7 million

26 Fleischmann et al DÄB 2016 Früh- und Neugeborene sowie Ältere sind besonders stark betroffen

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29 In Some Countries Sepsis Mortality decreased Australia: % auf 18.5% England: % auf 32.1% USA: % auf 29% Germany: ,8% auf 43,6%

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31 The German- speaking MoHs advocate a resolution on sepsis by the World Health Assembly Assembly

32 Ambassador for World Sepsis Day

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35 The proposed resolution shares the concerns of the World Sepsis Day movement and the GSA Concerned that sepsis continues to cause every year approximately six million deaths worldwide, most of which are preventable; Recognizing that sepsis as a syndromic response to infection is the final common pathway to death from most infectious diseases worldwide; Considering that sepsis has a unique and time-critical clinical course which in the early stages is highly amenable to treatment through early diagnosis and timely and appropriate clinical management

36 The proposed resolution shares the concerns of the World Sepsis Day movement and the GSA

37 (1) to include prevention, diagnosis and treatment of sepsis in national health system strengthening policies and processes, in the community and in healthcare settings according to international guidelines; (4) to develop and implement standard and optimal care and strengthen medical counter measures for diagnosing and managing sepsis in health emergencies, including outbreaks, through appropriate guidelines with a multisectoral approach; (5) to increase public awareness of the risk of progression to sepsis from infectious diseases, through health education, including on patient safety, in order to ensure prompt initial contact between affected persons and the health care system;

38 (6) using the term sepsis in order to enhance public awareness; (7) to promote research aimed at innovative means of diagnosing and treating sepsis across the lifespan, including research for new antimicrobial and alternative medicines, rapid diagnostic tests, vaccines and other important technologies, interventions and therapies; (8) to apply and improve the use of the International Classification of Diseases system to establish the prevalence and profile of sepsis and antimicrobial resistance, and.

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43 GSA Strategic Goals WHA/WHO: WSD needs to be mandated by a resolution on sepsis of the WHA/WHO 2. World Health Organization (WHO): Acknowleding that sepsis is the most common pathway to death following an infection 3. Global Burden of Disease Report (GBDR): Adequate recognition of the burden of sepsis 4. Adequate coding of sepsis in the WHO ICD-coding system: To achieve adequate representation of sepsis in the global and national disease reports 5. Raising public awareness and stimulate QI initiatives: Improve the knowledge on prevention and early signs of sepsis

44 We Thank Our Sponsors for Making the 1st World Sepsis Congress Possible

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47 Global Deaths from Infectious Diseases mostly occur in ressource poor countries

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49 Sessions 71, , ,207 Users 52,421 90, ,168 Page Views 220, , ,410 New Visitors 28,4 % 26,1 % 21,1 % Returning Visitors 71,6 % 73,9 % 78,9 %

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