Updates on NINR Strategic Plan and Funding Opportunities

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1 Updates on NINR Strategic Plan and Funding Opportunities Southern Nursing Research Society 2013 Paul A. Cotton, PhD, RD Health Paul Scientist A. Cotton, Administrator PhD, RD Office of Extramural Programs, National Institutes of Nursing Research Program Director, National Institute of Nursing Research

2 NIH Organizational Structure

3 National Institute of Nursing Research 1986 Established at the NIH as the National Center for Nursing Research (NCNR) 1993 Center elevated to an NIH Institute: National Institute of Nursing Research (NINR) 2011 NINR celebrated 25 year anniversary

4 NINR Director Dr. Patricia A. Grady April 3, Present

5 Overview: Mission New Strategic Plan: Bringing Science to Life 5 Areas of Focus Types of Grant Mechanisms New Funding Opportunity Announcements

6 NINR Mission To promote and improve health of individuals, families, communities, and populations. NINR supports and conducts clinical and basic research and research training on health and illness across the lifespan.

7 NINR Strategic Plan

The Science of Health Advancing Nursing Science by supporting research that: Focuses on promotion of health and quality of life Engages individuals as active participants in their own health

8 The Science of Health Advancing Nursing Science by supporting research that: Focuses on promotion of health and quality of life Engages individuals as active participants in their own health Includes interdisciplinary approaches; multiple health determinants Seeks innovative methods to optimize patient outcomes and contain costs Promotes health equity; eliminates health disparities

9 5 Areas of Focus Investing in: Health Promotion and Disease Prevention Advancing the Quality of Life: Symptom Management Palliative and End-of-Life Care Innovation Nurse Scientists

10 Health Promotion and Disease Prevention NINR will invest in research to discover new ways to promote health, prevent disease, and achieve long-term, positive health outcomes in individuals across the lifespan.

Health Promotion and Disease Prevention NINR will support research that: Develops innovative interventions to promote health and prevent illness,

11 Health Promotion and Disease Prevention NINR will support research that: Develops innovative interventions to promote health and prevent illness, particularly in minority and underserved populations Includes interdisciplinary, community, and other health care partnerships in the research process

12 Advancing Quality of Life NINR seeks to advance quality of life through a better understanding of symptoms, such as pain, fatigue, impaired sleep, and depression, in order to improve clinical- and self-management of illness.

13 Advancing Quality of Life NINR will support research that: Improves knowledge of biological and genomic mechanisms associated with symptoms Designs interventions to improve assessment and management of symptoms of acute and chronic illness for patients and caregivers

and address challenges faced by individuals

14 Palliative and End-of-Life Care NINR s palliative and end-of-life interdisciplinary research efforts apply behavioral, biological, and social science strategies: To understand and address challenges faced by individuals and caregivers Across care settings and cultural contexts

15 Palliative and End-of-Life Care NINR will support research to: Improve understanding of complex palliative and end-of-life care issues and choices Develop and test interventions that provide palliative care for individuals across the lifespan including those from diverse populations

16 Innovation NINR encourages the development of innovative strategies and new technologies to assist individuals, families, and providers in promoting health, preventing disease, and managing symptoms.

17 Innovation NINR will invest in research that: Develops new, and improves existing, health information technologies Encourages risk-taking, innovation, re-invention, and creativity, including high-risk and high-return concepts

meet current and future health challenges and to

18 Investing in Nurse Scientists NINR invests in the development of nurse scientists to enable them to meet current and future health challenges and to strengthen the scientific basis for clinical practice.

19 Investing in Nurse Scientists NINR will invest in training strategies and programs that: Support ongoing development of investigators at all career stages, including those from underrepresented communities Facilitate more rapid advancement from student to scientist

20 Overview of NINR Supported Activity Codes

21 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Senior Fellow Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

22 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Senior Fellow Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

23 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Senior Fellow Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

24 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Senior Fellow Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

25 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Senior Fellow Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

26 Training & Education Graduate Partnerships Program (GPP) NINR Summer Genetics Institute (SGI) Individual Post doc Awards (F32) Institutional Post doc Awards (T32) R01 support under PIs NINR SGI Pathway to Independence Awards (K99/R00) Career Development (K) Awards Individual Post-doc Awards (F33) NINR SGI Individual Pre doctoral Awards (F31) Institutional Pre doc Awards (T32) R01 support under PIs NINR SGI Career Development (K) Awards NIH Research Awards targeted to New Investigators NINR SGI Bachelor s Degree (senior year) Pre-Doctorate Post-Doctorate New Investigators Career Researchers

27 Pathways to Independence Award (K99/R00)

28 Independent Research Project Grants R01 R03 R15 P01 P20 P30 R41 and R42 R43 and R44

29 R01 - Research Project Grant Key Requirements: Supports discrete, specified projects Must have completed pilot work Application must tie together from theory to analysis Up to five years of support Budget Variable Modular

30 New Investigators/Early Stage Investigators New Investigator (NI) A PD/PI who has not obtained a substantial NIH research grant Early Stage Investigator (ESI) A New Investigator within 10 years of completing the terminal research degree or medical residency (or equivalent) Applies only to R01 applications New Investigators/Early Stage Investigators applications will be clustered together for review

31 Other R Series Grants R03: Small Research Grant Must show how it will lead to an R01 NINR only supports junior investigators for the R03 R15: Academic Research Enhancement Award Only eligible universities or colleges Includes students R21: Exploratory/Developmental Grant For innovative projects with high potential contribution to science

32 Small Business Opportunities R41, R42: Technology Transfer (STTR) Small business + research institution R43, R44: Innovative Research (SBIR) Research & development by small business

33 NINR Institutional Centers P01: Centers of Research of Critical Importance to NINR Established investigators Projects for innovative, high-impact, interdisciplinary research P20: Exploratory Relatively new programs of research Building of research expertise and teams for the future Administrative core + 3 research projects (2-3yrs duration) P30: Centers of Excellence Several years of demonstrated research success Administrative core + 3 research projects (2-3 yrs duration) Moving toward R01

34 NIH Common Fund Opportunities Stimulates highly innovative research ideas from new investigators of exceptional creativity, proposing research of very high potential impact Emphasis on innovation, preliminary data not required

NIH Common Fund Opportunities Provides a mechanism for exceptional, early career scientist to forgo traditional post-doctoral training Applicants

35 NIH Common Fund Opportunities Provides a mechanism for exceptional, early career scientist to forgo traditional post-doctoral training Applicants must be within a year of their terminal research degree/clinical residency Up to $300K/yr for 5 years

36 Timeline: New R01 Applications Receipt Date Scientific Review Council Review Award Date February 5 June October December June 5 October January April October 5 February May July

37 This image cannot currently be displayed. Timeline: New K Series, R03, R21, R15 Applications Application Type Receipt Date Scientific Review Council Review Award Date K Series February, June, October, 12 th June/July Oct/Nov Feb/March Aug/Oct January May December April July R03, R21, R15 (25 th ) February, June, October 16th June/July Oct/Nov Feb/March Aug/Oct January May December April July F Series April, August, December 8th June/July Oct/Nov Feb/March Aug/Oct January May Sept/Dec April July

38 NINR Intramural Training Opportunities NINR Intramural Training Director Dr. Mary Engler Contact:

NINR Intramural Research Discovering the underlying biological mechanisms of a range of symptoms, their effect on patients, and how patients respond to interventions The Symptoms Management Branch

39 NINR Intramural Research Discovering the underlying biological mechanisms of a range of symptoms, their effect on patients, and how patients respond to interventions The Symptoms Management Branch and Research Training Opportunities: Summer Genetics Institute June 3-28 Summer Interns Postdoctoral Fellowships (and K99, F33) Graduate Partnerships Programs Methodologies Boot Camp Series-July 22-26

NINR News Supports doctoral students currently enrolled in a school of nursing Institutional partnership: Applicants must attend or be accepted to a school of nursing with an NINRfunded T32

40 NINR News Supports doctoral students currently enrolled in a school of nursing Institutional partnership: Applicants must attend or be accepted to a school of nursing with an NINRfunded T32 Institutional Training Grant Individual partnership also now available For questions about the NINR GPP, please contact: Send an with NINR Graduate Partnership Program in the subject line to NINRIRPTraining@mail.nih.gov

41 2013 NINR Summer Genetics Institute Intensive program featuring lecture and handson laboratory training; open to students, faculty and clinicians SGI application period: opened January 14, 2013, and closes March 8, SGI Dates: June 3-28 See NINR website for more details for the 2013 program:

42 2013 NINR Fatigue/Sleep Methodologies Boot Camp One-week intensive research training course featuring lectures, classroom discussion and lab training in fatigue and sleep research methods Open to grad students, faculty and clinicians Registration opens April 1, 2013 and closes May 20, Dates: July See NINR website for more details for the 2013 program: ntramural/bootcamp.htm

43 Your NIH Application: What Does it Mean?

44 Decoding Your NIH Grant Number Application Type Activity Code Institute Code Serial Number Support Year Extension 1 R01 NR A1 1 = new 2 = renewal 3 = supplement 5 = noncompeting continuation R = Research project P = Program project or Center T = Training (institutional) F = Fellowship (individual) K = Career Development U = Cooperative agreement NR = NINR Unique, up to six digits Years of Continuous Funding A1 = Resubmission

Overview NIH Scientific Review of Grant Applications Applicant Grant Application Kit Assignment Process - Where reviewed? - What study section? - Who reviews?

45 Overview NIH Scientific Review of Grant Applications Applicant Grant Application Kit Assignment Process - Where reviewed? - What study section? - Who reviews? Scientific Review Group Initial Review Process - Critique presentation - Discussion - Scoring of application - Confidentiality Communication Process - Release of scores - Release of of statements Summary Statement Funding Institute/Center Second Level Review Process - Council review - Council recommendations - Confidentiality Applicant Notice of Grant Award

46 Where are NIH Applications Reviewed? WHERE Center for Scientific Review (CSR) MECHANISM Research Projects (R01, R21, R03) AREA (R15) Small Business Innovation Research (R41, R42, R43, R44) NINR (Office of Review) Pre- and Post-doctoral Fellowships (F31, F32, F33) Career Development Awards (K s ) Institutional Training Grants (T 32) Special Initiatives (RFAs, PARs)

47 Enhanced Peer Review : Scores Score for each core criteria used to evaluate application (range 1-9) Score for Overall impact of application (range 10-20)

48 Enhanced Peer Review : F Scoring Criteria Core Criteria Fellowship Applicant Sponsors, Collaborators and Consultants Research Training Plan Training Potential Institutional Environment and Commitment Overall Impact Likelihood the fellowship will enhance the candidate s potential for, and commitment to, a productive independent research career in a health-related field

49 Enhanced Peer Review: K Criteria Core Criteria Candidate Career Development Plan Research Plan Mentors, Consultants and Collaborators Environment and Institutional Commitment Overall Impact Likelihood for the candidate to maintain a strong research program

50 Other Criteria: Factored into Overall Impact Protection of Human Subjects Vertebrate Animal Welfare Inclusion of Women, Minorities and Children Biohazards

51 Scoring of Criteria and Overall Impact Applications scored on each review core criterion using a scale of 1-9. The overall impact of the application is determined by using the same scale of 1-9 The impact score is not the average of the criterion scores

52 Scoring System Impact Score Descriptor 1 Exceptional High Impact 2 Outstanding 3 Excellent Moderate Impact Low Impact 4 Very Good 5 Good 6 Satisfactory 7 Fair 8 Marginal 9 Poor 52

53 NIH Scoring Scale Impact Score Descriptor 1 Exceptional High Impact Moderate Impact Low Impact 2 Outstanding 3 Excellent 4 Very Good 5 Good 6 Satisfactory 7 Fair 8 Marginal 9 Poor

54 NIH Scoring Scale: Additional Guidance Impact Score Descriptor Strengths/Weaknesses 1 Exceptional Exceptionally strong/no weaknesses High Impact 2 Outstanding Extremely strong/negligible weaknesses 3 Excellent Very strong/some minor weaknesses 4 Very Good Strong/numerous minor weaknesses Moderate Impact Low Impact 5 Good Strong/ at least 1 moderate weakness 6 7 Satisfactory Some strengths/some moderate weaknesses Fair Some strengths/ at least 1 major weaknesses 8 Marginal Few strengths/few major weaknesses 9 Poor Very few strengths/many major weaknesses

55 Additional Scoring Guidance Minor Weakness: Does not lessen impact Moderate Weakness: Lessens impact Major Weakness: Severely limits impact

56 Example of Scoring for a K Application Criterion Rev. 1 Rev. 2 Rev. 3 Overall Impact Score: Candidate Career plan Research plan Mentor(s) Environment IS Average score:

57 Study Section Meeting

58 There is no amount of Grantsmanship that will turn a bad idea into a good one but there are many ways to disguise a good idea Dr. William F. Raub Deputy and Acting Director NIH ( )

59 Scientific Review Criteria (Level 1 Review) Criteria factored into overall impact score Significance Investigators Innovation Approach Environment Human Subjects DSMB/P Additional considerations: Not factored into overall impact score Budget Foreign institutions Resource Sharing

60 Scientific Review Groups Make recommendations: Scientific and technical merit Bars to award human subjects, vertebrate animals, biohazards Overall Impact/Priority scores Written critiques (summary statements) Confidentiality: All materials, discussions, documents (except those in the public domain) All questions referred to Scientific Review Officer (SRO) Review is closed to the public Study Sections Do not make funding decisions

61 2 Level System for Application Review 1 st Level Scientific Review Group (SRG) Independent outside reviewers Evaluate scientific merit & significance Recommend length and level of funding 2 nd Level National Advisory Council Assesses Quality of SRG Review Makes Recommendation to Institute Staff on Funding Evaluates Program Priorities and Relevance Advises on Policy

62 National Advisory Council (Level 2 Review) National Advisory Council assesses quality of Level 1 review Cannot change overall impact/priority score from SRG Can designate application as High or Low program priority National Advisory Council s meet 3 times yearly: January, May, and September

63 NIH Peer Review Websites Enhancing Peer Review Initiative Office of Extramural Research Peer Review National Institute of Nursing Research Center for Scientific Review

64 Office of Extramural Programs: Program Director Contacts

65 Program Directors Section on Neuroscience, Genetics, & Symptom Management Dr. Susan Marden Portfolio includes: Symptom Management (e.g. Pain, Fatigue, Nausea) Dr. Lois Tully Portfolio includes: Genetics & Biology Interim Portfolio includes: Neuroscience (conditionscognitive function; diseases acute, rehabilitation, caregiving)

Lynda Hardy 301 594 5976 Portfolio includes: Child Health and Family Health (families and parenting/multigenerational; family health

66 Program Directors Section on Child & Family Health, & Health Disparities Dr. Paul Cotton Portfolio includes: Health Disparities Health and Risk Behaviors, Environmental Health, Men's Health. Dr. Lynda Hardy Portfolio includes: Child Health and Family Health (families and parenting/multigenerational; family health and illness; family interactions and networks). HIV/AIDS and Immune Function. Dr. Martha Matocha Portfolio includes: Preterm Birth/Infant Development, Sleep, Renal/Urinary Incontinence

67 Program Directors Section on Immunology, Infectious Disease, & Chronic Disorders Dr. Lynda Hardy Portfolio includes: HIV/AIDS and Immune Function.

Program Directors Section on Acute & Long Term Care, End of Life, & Training Dr. Noreen Aziz 301 594 2542 Portfolio includes: Palliative Care and End of Life, Long Term Care Dr.

68 Program Directors Section on Acute & Long Term Care, End of Life, & Training Dr. Noreen Aziz Portfolio includes: Palliative Care and End of Life, Long Term Care Dr. David Banks Portfolio includes: Training and Fellowships in All Science Areas Dr. Karen Huss Portfolio includes: Acute Care kh6 (cardiopulmonary and critical care) Institutional Care Dr. Donna Jo McCloskey Portfolio includes: Institutional Training Grants (T32) and Center Grants in All Science Areas

69 Current NINR Funding Opportunities

74 NIH Updates Resubmission Deadlines: For deadlines on/after January 25, 2011, applicants must submit their Resubmission application (A1) within thirty-seven months of the initial New, Renewal, or Revision application due date

75 NIH Updates New K page limits for due dates after Jan. 7, 2011 Mentoring Plan - 6 pages Statements by Mentors, Contributors - 6 pages Description of Institutional Environment - 1 page Commitment to Candidate's Research Career Development - 1 page html

76 Reminders Population tracking reports need to be complete and accurate Budgets over $500,000/ year in direct costs need prior approval Budgets over $350,000/year in direct costs are considered high budget and are reviewed by the NINR Council

77 NINR Program Directors Contact NINR Program Directors for Assistance Common Topics: o o o o o o Ideas for research proposals Questions regarding FOA s Guidance with application preparation Questions regarding population tracking Any issues regarding your funded application General concerns/comments

78 Resources Funding Opportunities: NIH Guide for Grants & Contracts: NINR Frequently Asked Questions: NINR Data Safety Monitoring Policy: Symptom Management Research at NINR: End of Life Research at NINR:

79 Funding Opportunities All current NINR Funding Opportunity Announcements, including RFAs and Program Announcements (PAs), as well as Notices of interest from NIH, are available on the NINR web site at: A/OEP/FundingOpportunities/default.htm

80 Investigator Initiated PA : Research Project Grant (Parent R01): Expires: September 8, 2014 PA : NIH Exploratory/Developmental Research Grant Program (Parent R21): Expires: September 8, 2014 Further investigator initiated opportunities are available by mechanism on our website.

81 ADM3 Funding Opportunities: RFA RFA-NR /003: The Influence of the Microbiome on Preterm Labor and Delivery (R01)/ (R21): & NR html Due date: 5/10/13

82 ADM4 Funding Opportunities: PAs PA : Maternal Nutrition and Pre-pregnancy Obesity: Effects on Mothers, Infants and Children (R01): Expires: January 8, 2015 PA /328/329: Healthy Habits: Timing for Developing Sustainable Healthy Behaviors in Children and Adolescents (R01)/ (R03)/ (R21): & & html Expires: September 8, 2014

83 ADM5 Funding Opportunities: PAs PA /331/332: mhealth Tools to Promote Effective Patient Provider Communication, Adherence to Treatment and Self Management of Chronic Diseases In Underserved Populations (R01)/ (R03)/ (R21): & & Expires: September 8, 2014 PA : Obesity and Asthma: Awareness and Management (R01): Expires: September 8, 2014

84 ADM6 Funding Opportunities: PAs PA /134: Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01)/ (R21): & Expires: January 8, 2016

Fundamentals of the NIH. Erica Brown, PhD Director, NIH AREA Program Extramural Policy Coordination Officer National Institutes of Health

Fundamentals of the NIH. Erica Brown, PhD Director, NIH AREA Program Extramural Policy Coordination Officer National Institutes of Health Fundamentals of the NIH Erica Brown, PhD Director, NIH AREA Program Extramural Policy Coordination Officer National Institutes of Health 1 Overview The big picture Finding funding opportunities Interacting