Grants.gov Manual for Windows Users. NIH Applications o R01 Program Project Grants

Transcription

1 Grants.gov Manual for Windows Users NIH Applications o R01 Program Project Grants November 21, 2006 This workbook also contains information and original material from the PHS Grants.Gov application Guide SF 424 (R&R) which can be found at as well as the Grants.gov manual found at 0

2 The purpose of this handout is to assist with the preparation of applications submitted via the grants.gov system. The Federal Financial Assistance Management Improvement Act of 1999, also known as Public Law (P.L ), was enacted on November The purposes of the Act are to (1) improve the effectiveness and performance of Federal financial assistance programs, (2) simplify Federal financial assistance application and reporting requirements, (3) improve the delivery of services to the public, and (4) facilitate greater coordination among those responsible for delivering services. Grants.gov was developed in response to PL Reminders: The submits the final proposal application to Grants.Gov The application is a package of forms that have to be completed. It is NOT web based. When sharing the file with a collaborator you are giving the file to that person (just like a Word document). Be sure to keep track of the file versions! Use Internet Explorer You need to enable cookie support and pop-ups Complete the SF 424 R&R form first as it populates other forms. And when populating the NIH forms you need to override the information in the PI section. The file does NOT automatically save. You have to click on SAVE to save the data entered. Submitting the Application -- The following steps must be taken in order to submit a PHS (NIH) grant application through Grants.gov: 1. Registration of GTRC & GTARC are completed in both the Grants.Gov system and in the era Commons (NIH s system). 2. Ensure that you have an era Commons Account. 3. Find a Funding Opportunity Announcement (FOA) using the Grants.gov Apply feature that reflects use of the SF424 (R&R) forms and electronic submission through Grants.gov. 4. MAC users must download Citrix client or Windows Emulator (see Appendix for Emulator Instructions) (For MAC Users, the application package must be downloaded prior to downloading the Citrix Clients.) Grants.gov should release a MAC version in December 2006 (but it has limitation). 5. Download PureEdge Viewer (or upgrade) 6. Download the associated Application Package from Grants.gov. 7. Complete the appropriate application components, including all necessary PDF attachments. (All - PureEdge attachments MUST be in PDF format!) Upload all attachments into the appropriate application component. DO NOT: Use special characters in file names Write-protect the PDF file; you should disable all security features in the PDF Include headers or footers in the text pages Scan text attachments. Generate using word processing package and then convert to PDF. For more information: 1

3 8. Submit the completed application to the via the Proposal File Upload System at OSP asks for the completed application 5 business days prior to the deadline. Reminder: Both the Chair s and the Dean s signatures or their designee(s) are required on the routing form. The chair may sign for the Dean but his signature must be on the Dean s section of the routing form. The Submit button becomes active only after all mandatory elements of the grant application package have been completed including attachment of forms and mandatory fields. DO NOT submit via Grants.gov, the contracting officer does that! 9. Coordinate with your Contracting Officer (Anita McKinney for NIH) to submit the application by the date specified in the FOA. (Keep a copy locally at the Applicant Organization/Institution.) 10. After agency validation, receive the agency tracking number (accession number). 11. PD/PI and Signing Official (Anita) complete review the proposal in the era Commons. If no changes are made within 2 business days, the submission is automatically accepted into the system. The following sections explain each step in more detail. Grants.Gov The URL for grants.gov is The system can be utilized for both finding funding as well as submitting an application via grants.gov to a specific federal agency. The first step in utilizing the grants.gov system is to download the PureEdge Viewer (or upgrade if necessary). Note: GTRC is registered; PI/PDs do not need to register with the system. The application will be submitted by the Contracting Officer who is a registered user for grants.gov Click on the first Apply for Grants link on the left (red) part of the web site. 2

4 In the Apply for Grants portion IMPORTANT: In order to complete the application form, PureEdge Viewer will need to be downloaded onto your PC. You may need to coordinate with your department s CSR to download software. Click on the link Download PureEdge Viewer. See Appendix for handout on Downloading PureEdge Viewer for Windows Users. Download (and Install) the PureEdge Viewer (See website for directions) If you ve already downloaded the PureEdge Viewer, you still may need to upgrade your Viewer to a more recent release. Be sure to check before downloading the application file as you ll get an error message. 3

5 Downloading the Application From the screen with the APPLY FOR GRANT screen simply click on the link within STEP 1 Download a Grant Application Package and Instructions. Below is the Download Application Package Screen. You will already need to have searched for the funding opportunity that you are applying for. Simply key in the CFDA number or Funding Opportunity Number into the text field and click on Download Package If you do not know the FON then simply click on the link to Find Grant Opportunity. On the next screen click on Search, then click on Advance SEARCH to get to this screen. In the keyword search key in R01 parent and then click on search. 4

6 This application is ONLY for unsolicited applications. If applying for a solicited program, find that specific application (if you have the NIH summary there should be a link to the application within Grants.gov). 5

7 Click on the link How to Apply. Click on Download Some opportunities maybe have multiple listings, simply select the one that you want and click the download link. 6

8 You should key in your in the text field in case any changes or modifications are made to the application so that you can receive an update regarding those changes. The next steps involve downloading both the instructions for the solicitation and downloading the application package. You should key in your in the text field in case any changes or modifications are made to the application so that you can receive an update regarding those changes. The next steps involve downloading both the instructions for the solicitation and downloading the application package. To download the application, simply click on the link to Download Application Package. The application will open in the browser. Be sure to save the file to your desktop. Close your browser and then open the file from your PC. DO NOT work on the file within the browser. Be sure to save the application to your desktop (or where ever you want it saved) and then run the An application notice from regarding your computer a change and in not a through funding your opportunity browser. that had been previously downloaded (This is not the same CFDA number as the example we have been using). Be sure to download the Application Instructions, too! 7

9 When you are saving the file you may receive the above Warning message. Just click YES and then name the file. The next time you save the file you will get a message asking to over right the file. Click Yes. Close your browser and then open the file up from your PC. Find the application where it was saved (i.e., Desktop) and open the file. Be sure you ve downloaded the correct application as each application is SPECIFIC to the solicitation. You cannot change the info regarding the Opportunity Title, CFDA, etc. within the application package. (1) 8

10 Completing the Application Package When you select a funding opportunity in Grants.gov Apply, verify that the information shown in the Grant Application Package screen corresponds to the funding opportunity for which you wish to apply. Grants.gov autopopulates the following information: Opportunity Title Offering Agency CFDA Number CFDA Description Opportunity Number Competition ID Opportunity Open Date Opportunity Close Date Agency Contact Be sure you are using Version 2A Forms! Instructions for completing the specific application package are listed at the bottom of the screen (2 in blue). Use the scroll bar to move up and down the application package. Each Grants.gov application package has a cover page that lists all forms necessary to complete the package (3). Forms are divided into two groups mandatory and optional. The cover page also acts as the central point from which you will navigate through completion of all forms. Field level help is available within the PureEdge Viewer. Simply click on the symbol at the top of the form that looks like and arrow and a question mark? to turn it on (or off). (4) 9

11 Completing the Application Package (Continued) Begin the application by populating the field Application File Name with text. Since the field name needs to be unique, we suggest that you begin with your last name and then the title of your project. Use an underscore in between your last name and the title you want for proposal. For example, Powell_My NIH Proposal Title. Spell check is available within each form (1). You can save your application at any time by clicking the Save button at the top of the screen (2). Note: If you choose to save your grant application package before you have fully completed it you will receive an error message. This error message is used to warn the applicant that the grant application is not yet completed. Click OK and you will be able to save your grant application package and complete it at another time. 2 1 How a title should look Last Name of PI and then an _ (underscore) and then the title of the proposal. To open any form, click on it (1) and then click the Open Form button (2). We are opening the SF 424 (Research & Related) from. You should begin with the SF 424 R&R as it populates some of the other forms. 10

12 The yellow highlights are the mandatory fields that must be populated in order to complete the form. As you complete the mandatory sections, the yellow highlights will disappear. If you downloaded the R01 Parent from GT s OSP, then some of this information will already be populated. Click on the Next button to complete the rest of the forms. There may be a number of screens to click thorough before the form is completed. Once all data have been entered, click the Close Form button at the top of the form. You will be returned to the Grant Application Package screen. Item 1, Type of Submission Pre-application - do not use unless specifically noted in FOA Changed/Corrected Application To be used only when correcting an application that failed system validations. This is NOT a resubmission (amendment). Item 8, Type of Application--New Terminology New is the same Resubmission is equivalent to a Revision (a revised or amended application) Renewal is equivalent to a Competing Continuation Continuation is equivalent to a Progress Report. For the purposes of NIH and other PHS agencies, the box for Continuation will not be used and should not be checked. Revision is somewhat equivalent to a Competing Supplement Item 10, CFDA Number Ignore for NIH Item 11, Title Title for the federal agency and is limited to 81 characters including spaces between words and punctuation. Item 12, Areas Affected by Project Enter N/A if not applicable Item 13, Project Period Use the mm/dd/yyyy format Item 15, PI Info The info in this section needs to be the same as what is located in the NIH Commons database. This includes the spelling of your name to the title in the system. The above info from GTRC will populate this section delete it and key in your own information. 11

13 APPLICATION FOR FEDERAL ASSISTANCE SF 424 (R&R) 1. * TYPE OF SUBMISSION Pre-application Application Changed/Corrected Application 2. DATE SUBMITTED 3. DATE RECEIVED BY STATE 4. Federal Identifier Applicant Identifier State Application Identifier 5. APPLICANT INFORMATION * Organizational DUNS: * Legal Name: Department: Georgia Tech Research Corporation Division: * Street1: 505 Tenth Street NW Street2: * City: Atlanta County: Fulton * State: GA: Georgi Province: * Country: UNITED ST * ZIP / Postal Code: Person to be contacted on matters involving this application Prefix: * First Name: Middle Name: * Last Name: Suffix: Anita McKinney * Phone Number: Fax Number: anita.mckinney@osp.gatech.edu 6. * EMPLOYER IDENTIFICATION (EIN) or (TIN): 7. * TYPE OF APPLICANT: H: Public/State Controlled Institution of Higher Education 8. * TYPE OF APPLICATION: New Other (Specify): Small Business Organization Type Resubmission Renewal Continuation Revision Women Owned Socially and Economically Disadvantaged If Revision, mark appropriate box(es). A. Increase Award B. Decrease Award C. Increase Duration D. Decrease Duration E. Other (specify): 9. * NAME OF FEDERAL AGENCY: National Institutes of Health 10. CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBER: * Is this application being submitted to other agencies? Yes No What other Agencies? TITLE: 11. * DESCRIPTIVE TITLE OF APPLICANT'S PROJECT: 12. * AREAS AFFECTED BY PROJECT (cities, counties, states, etc.) 13. PROPOSED PROJECT: 14. CONGRESSIONAL DISTRICTS OF: * Start Date * Ending Date a. * Applicant b. * Project GA-005 GA PROJECT DIRECTOR/PRINCIPAL INVESTIGATOR CONTACT INFORMATION Prefix: * First Name: Middle Name: * Last Name: Suffix: Position/Title: Department: * Organization Name: Division: Georgia Tech Research Corporation * Street1: Street2: * City: Atlanta County: Fulton * State: GA: Georgi Province: * Country: UNITED ST * ZIP / Postal Code: * Phone Number: Fax Number: * OMB Number: Expiration Date: 04/30/2008

14 SF 424 (R&R) APPLICATION FOR FEDERAL ASSISTANCE Page ESTIMATED PROJECT FUNDING 17. * IS APPLICATION SUBJECT TO REVIEW BY STATE EXECUTIVE ORDER PROCESS? a. * Total Estimated Project Funding b. * Total Federal & Non-Federal Funds c. * Estimated Program Income a. YES THIS PREAPPLICATION/APPLICATION WAS MADE AVAILABLE TO THE STATE EXECUTIVE ORDER PROCESS FOR REVIEW ON: DATE: b. NO PROGRAM IS NOT COVERED BY E.O ; OR Anita PROGRAM HAS NOT BEEN SELECTED BY STATE FOR REVIEW 18.By signing this application, I certify (1) to the statements contained in the list of certifications* and (2) that the statements herein are true, complete and accurate to the best of my knowledge. I also provide the required assurances * and agree to comply with any resulting terms if I accept an award. I am aware that any false, fictitious, or fraudulent statements or claims may subject me to criminal, civil, or administrative penalties. (U.S. Code, Title 18, Section 1001) * I agree * The list of certifications and assurances, or an Internet site where you may obtain this list, is contained in the announcement or agency specific instructions. 19. Authorized Representative Prefix: * First Name: Middle Name: * Last Name: Suffix: McKinney * Position/Title: Contracting Officer * Organization: Georgia Tech Research Corporation Department: Division: * Street1: 505 Tenth Street NW Street2: * City: Atlanta County: Fulton * State: GA: Georgi Province: * Country: UNITED ST * ZIP / Postal Code: * Phone Number: Fax Number: * anita.mckinney@osp.gatech.edu * Signature of Authorized Representative * Date Signed Completed on submission to Grants.gov Completed on submission to Grants.gov 20. Pre-application Add Attachment Delete Attachment View Attachment 21. Attach an additional list of Project Congressional Districts if needed. Add Attachment Delete Attachment View Attachment OMB Number: Expiration Date: 04/30/2008

15 Project/Performance Site Locations Equivalent to the PHS 398 Form Page 2 Performance Site section Collects individual data for up to 8 locations >8 locations information is provided in an attachment (not structured data, just text) Format for the >8 attachment available on SF424 (R&R) Forms Page: 13

16 Other Project Information Other Project Information When you are finished entering the data in any of the forms, click the Close Form button. Your work will be temporarily saved. Note: In order to save your complete application package, you must click the Save button on the application cover page. 6. Project Summary PDF File No longer than 30 lines of text. Should be self-contained description of the project and should contain a statement of objectives and methods employed. 7. Project Narrative PDF File Include two-three sentences on the Relevance of this research to the public health. Be succinct and use plain language that can be understood by a general, lay audience. 8. Bibliography & Reference Cited Formally known as the Literature Cited section. PDF File Citations for references in the Project Narrative 9. Facilitates & Other Resources PDF File Identify the facilities to be used and if appropriate their capacities, capabilities, etc. If select agents, see notes in grants manual 10. Equipment PDF File List of major equipment ALREADY available for this project. As well as location and pertinent capabilities. 14

17 Credentials is a REQUIRED field for NIH for all Senior or Key Personnel. This is your Commons ID. Typically, first/last name combo. Call Nadia at to verify. Reminders: All of the PIs MUST be in the era Commons System (at NIH). Current and Pending Support isn t necessary. NIH uses a system called JIT or Just in Time for this information. 15

18 Attaching a File To attach a file to your application, simply click on the Add Attachment button. This will bring up a dialog box. Simply, find the file you want to attach. In this case, we are looking on the desktop for my project summary file. After the file is attached, you may view the file. If you want to make changes to the file, be sure to make the changes on the file on your desktop and delete and then replace the file with the modified one. Some folks have encountered problems by making changes while viewing the file (and the changes are not saved within PureEdge). 16

19 The document (SF 424 R&R) has now moved from the Mandatory Documents box to the Mandatory Completed Documents for Submission box. All Mandatory Documents must be moved to the Mandatory Completed Documents for Submission box in order to submit your application. (This process of completing the form and then moving it to the completion box must be done for all mandatory forms) All mandatory fields (yellow highlights) in all mandatory forms have been completed and moved to the mandatory completed documents for submission Optional forms have been completed and moved to the Optional Completed Documents for Submission. The Save button has be clicked AFTER all documents have been moved to the completed documents section (both the mandatory and the optional if applicable) R&R Budgets Use the budget wizard to assist with completing the budget section. The URL is Simply key in the text and the amounts for the budget. Click on the Next button to continue onto the next budget screen. You chose which Budget Form to use based upon NIH regulations. Choose EITHER the R&R Budget (if over $250,000 in direct costs per year) OR the Modular Budget. You DO NOT complete both! Move over the one that you ve completed. 17

20 Continue populating the form with your budget information. If you have more than one year, click on the Next Period. Note: ALL yellow fields need to be completed including the Budget Justification before you can launch the next budget period. The system will calculate your cumulative budget for you. 18

21 Be sure to upload your budget justification to the budget section. A. Senior/Key Person Allows 8 as named individuals & structured data 8 information is provided in an attachment (not structured data, just text) Info for PD/PI must be entered, even if $ = 0 B. Other Personnel Postdocs, Grad Students, Undergrads: captures # only NIH will request more detail in Budget Justification Change from Percent Effort to Person Months Must enter either Calendar, Academic and/or Summer for all Senior/Key Persons Incorporated this business process change throughout--see 4/2006 Interim change to PHS 398 & PHS 2590 Progress Report, including Budget Pages, Other Support documentation, Key Personnel Reports, etc. FAQs and Calculator available at: C. Equipment Allows itemization of up to equipment items: details provided in an attachment total funds requested in attachment are entered in Line 11 D. Travel R&R separates out Domestic & Foreign This will not change any NIH policy/practice. We will continue to award as a single category. E. Participant/Trainee Support Costs Will not be used by NIH unless specifically noted in an announcement Tuition Remission will continue to be included in Section F Other Direct Costs F. Other Direct Costs 19

22 Itemizes: Supplies, Publication Costs, Consultants, ADP/Computer Services, Consortium Costs, Equipment or Facility Rental/User Fees, Alterations & Renovations Have included agency-specific instructions to use this section to also account for patient care costs & tuition remission F5. Has total amount for all SubAwards Next Period Button: At the top of the last budget page. All required data fields in this component must be entered before this button is available. This includes the Budget Justification. R&R Subaward Budget Attachment Form Use for detailed budget from any consortium grantee only when the prime is submitting detailed budget Do not use if prime is submitting Modular Budget Consortium grantee(s) must have PureEdge installed Allows up to 10 separate budget attachments one for each consortium grantee Applicant sends the R&R budget component to the consortium grantee for completion; it is returned to the applicant; applicant attaches it in this component Applicant still needs to include the total costs for all consortiums in their own detailed budget, Section F.5 Over 10 SubAward Budgets? Include them in the main budget justification. 20

23 Clicking on the Select to Extract the R&R Additional Senior/Key Person Form button produces the PureEdge form shown on the right. Version 2A This is the only change in the forms for packages noted as Version 2A. Captures structured data for up to 40 Senior/Key Persons. Enter Senior/Key Person 1, click the Next Person button to display the fields for Profile Senior/Key Person 2. After the first 8 are entered (PI + 7 others), the Select to Extract the R&R Additional Senior/Key Person Form button becomes active. Click to open a new page that allows up to four additional Senior/Key Person (PureEdge) components to be attached (each containing another 8 individuals). 21

24 Research Plan Helpful Hints Create as a single document using any word processing software. Separate at the end before uploading. Do not include headers or footers Include a section heading as part of the text (i.e., Specific Aims, Background & Significance) Avoid 2-column format for text (difficult for reviewers to read electronically) Full-sized glossy photographs of material such as electron micrographs or gels must only be included within the page limitations of the Research Plan. The maximum size of images to be included should be approximately 1200 x 1500 pixels using 256 colors. Figures must be readable as printed on an 8.5 x 11 inch page at normal (100%) scale. 22

25 Investigators must use image compression such as JPEG or PMG. Do not include figures or photographs as separate attachments either in the Appendix or elsewhere in the application. Page Limitations for R01 Do not exceed 25 pages for Items 2 5. All tables, graphs, figures, diagrams, and charts must be included within the 25-page limit. Be succinct and remember that there is no requirement to use all 25 pages allotted to items 2-5 of the Research Plan. Appendix Material Allows up to 10 separate attachments Will be stored separately in the era Grant Folder, not as a part of the main application grant image Will be accessible to appropriate NIH staff and peer reviewers See recent changes in Appendix Material, Guide Notice NOT-OD : Begin each text section of the Research Plan with a section header (e.g., Introduction, Specific Aims, Background & Significance, etc). Field Name 1. Introduction to Application (for Resubmission or Revision only) Instructions Use only if you are submitting an R&R Resubmission or Revision (Cover Page Item 8). The Introduction may not exceed 1-3 pages for resubmissions (previously known as a revision or amendment) or one page for revisions (previously known as competing supplements). Page limits for the Introduction vary for specialized mechanisms (e.g., R03 and R21 applications). Applicants must follow the page limits that are outlined in the specific announcement. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. 2. Specific Aims List the broad, long-term objectives and the goal of the specific research proposed, for example, to test a stated hypothesis, create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop new technology. One page is recommended. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. 3. Background and Significance Briefly sketch the background leading to the present application, critically evaluate existing knowledge, and specifically identify the gaps that the project is intended to fill. State concisely the 23

26 Field Name 4. Preliminary Studies/Progress Report 5. Research Design and Methods Instructions importance and health relevance of the research described in this application by relating the specific aims to the broad, long-term objectives. If the aims of the application are achieved, state how scientific knowledge or clinical practice will be advanced. Describe the effect of these studies on the concepts, methods, technologies, treatments, services or preventative interventions that drive this field. Two to three pages are recommended. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. Preliminary Studies. For new applications, use this section to provide an account of the PD/PI s preliminary studies pertinent to this application, including his/her preliminary experience with and outreach to the proposed racial/ethnic group members. This information will also help to establish the experience and competence of the investigator to pursue the proposed project. Except for Exploratory/Development Grants (R21/R33), Small Research Grants (R03), and Phase I Small Business Research Grants (R41/R43), peer review committees generally view preliminary data as an essential part of a research grant application. Preliminary data often aid the reviewers in assessing the likelihood of the success of the proposed project. Progress Report for Renewal (previously known as Competing Continuation) and Revision (previously known as Supplemental) Applications. A Progress Report must be provided for renewal and revision applications. Provide the beginning and ending dates for the period covered since the project was last reviewed competitively. Summarize the previous application s specific aims and the importance of the findings. Provide a succinct account of published and unpublished results, indicating progress toward their achievement. Discuss any changes in the specific aims as a result of budget reductions. A list of publications, manuscripts accepted for publication, patents, and other printed materials will be included in Section 7; do not include that information here. Six to eight pages are recommended for the narrative portion of this section. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. Describe the research design conceptual or clinical framework, procedures, and analyses to be used to accomplish the specific aims of the project. Unless addressed separately in Item 17, include how the data will be collected, analyzed, and interpreted as well as the 24

27 Field Name 6. Inclusion Enrollment Report 7. Progress Report Publication List Instructions data-sharing plan as appropriate. Describe any new methodology and its advantage over existing methodologies. Describe any novel concepts, approaches, tools, or technologies for the proposed studies. Discuss the potential difficulties and limitations of the proposed procedures and alternative approaches to achieve the aims. As part of this section, provide a tentative sequence or timetable for the project. Point out any procedures, situations, or materials that may be hazardous to personnel and the precautions to be exercised. Although no specific number of pages is recommended for the Research Design and Methods section, be as succinct as possible. There is no requirement that all 25 pages allotted for items 2-5 be used. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. If the renewal or revision application involves clinical research, then you must report on the enrollment of research subjects and their distribution by ethnicity/race and sex/gender. See What Form Should PDs/PIs Use for Population Tracking? (New Versus Old) for more detailed instructions on which Target and Enrollment Report or Table to use. List the titles and complete references to all appropriate publications, manuscripts accepted for publication, patents, and other printed materials that have resulted from the project since it was last reviewed competitively. For publicly available citations, URLs or PMC submission identification numbers may accompany the full reference. Note copies of these publications are no longer accepted as appendix material. As part of the Appendix material you may include only up to 3 of the following types of publications: Manuscripts and/or abstracts accepted for publication but not yet published: The entire article should be submitted as a PDF attachment. Manuscripts and/or abstracts published, but a free, online, publicly available journal link is not available: The entire article should be submitted as a PDF attachment. Patents directly relevant to the project: The entire document should be submitted as a PDF attachment. (Do not include unpublished theses, or abstracts/manuscripts submitted (but not yet accepted) for publication.) 25

28 Field Name Instructions Note, publications and/or abstracts in press should no longer be included in the appendix material. Include the URL or PMC submission identification numbers along with the full reference in the Bibliography and References cited section, the Progress Report Publication List section, and/or the Biographical Sketch section. Human Subjects Sections Field Name 8. Protection of Human Subjects 9. Inclusion of Women and Minorities 10. Targeted/Planned Enrollment Table Instructions This section covers only the initial information regarding the Protection of Human Subjects. Follow the instructions in Part II, Supplemental Instructions for Preparing the Human Subjects Section of the Research Plan. See separate sections below for other human subjects related sections that may apply. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. Unless an explanation is necessary, if Human Subjects research is not involved, and you have checked the box marked No on the Other Project Information Component, you need not include any additional information in this section. To determine if Inclusion of Women and Minorities applies to this application, follow the instructions in Part II, Supplemental Instructions for Preparing the Human Subjects Section of the Research Plan. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. If this application involves the Inclusion of Women and Minorities, complete the Targeted/Planned Enrollment Table. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. 11. Inclusion of Children To determine if Inclusion of Children applies to this application, follow the instructions in the Supplemental Instructions for Preparing the Human Subjects Section of the Research Plan. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. Other Sections 26

29 Field Name Instructions 12. Vertebrate Animals If you indicated that Vertebrate Animals are involved in this project, address the following five key points. In addition, when research involving vertebrate animals will take place at collaborating site(s) or other performance site(s), provide this information before discussing the five points. Although no specific page limitation applies to this section of the application, be succinct. 1. Provide a detailed description of the proposed use of the animals in the work outlined in the Research Design and Methods section. Identify the species, strains, ages, sex, and numbers of animals to be used in the proposed work. 2. Justify the use of animals, the choice of species, and the numbers to be used. If animals are in short supply, costly, or to be used in large numbers, provide an additional rationale for their selection and numbers. 3. Provide information on the veterinary care of the animals involved. 4. Describe the procedures for ensuring that discomfort, distress, pain, and injury will be limited to that which is unavoidable in the conduct of scientifically sound research. Describe the use of analgesic, anesthetic, and tranquilizing drugs and/or comfortable restraining devices, where appropriate, to minimize discomfort, distress, pain, and injury. 5. Describe any method of euthanasia to be used and the reasons for its selection. State whether this method is consistent with the recommendations of the Panel on Euthanasia of the American Veterinary Medical Association. If not, present a justification for not following the recommendations. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. For those applicants familiar with the PHS398, please note that the Literature Cited section of the Research Plan is now captured as Bibliography & References Cited. Refer to Item 8 in the Other Project Information Component for instructions. 13. Select Agents Select Agents are hazardous biological agents and toxins that have been identified by HHS or USDA as having the potential to pose a severe threat to public health and safety, to animal and plant health, or to animal and plant products. CDC maintains a list of 27

30 Field Name Instructions these agents. See If the activities proposed in your application involve only the use of a strain(s) of Select Agents which has been excluded from the list of select agents and toxins as per 42 CFR 73.4(f)(5), the Select Agent requirements do not apply. Use this section to identify the strain(s) of the Select Agent that will be used and note that it has been excluded from this list. The CDC maintains a list of exclusions at If the strain(s) is not currently excluded from the list of select agents and toxins but you have applied or intend to apply to HHS for an exclusion from the list, use this section to indicate the status of your request or your intent to apply for an exclusion and provide a brief justification for the exclusion. If any of the activities proposed in your application involve the use of Select Agents at any time during the proposed project period, either at the applicant organization or at any other performance site, address the following three points for each site at which Select Agent research will take place. Although no specific page limitation applies to this section, be succinct. 1. Identify the Select Agent(s) to be used in the proposed research. 2. Provide the registration status of all entities* where Select Agent(s) will be used. If the performance site(s) is a foreign institution, provide the name(s) of the country or countries where Select Agent research will be performed. *An entity is defined in 42 CFR 73.1 as any government agency (Federal, State, or local), academic institution, corporation, company, partnership, society, association, firm, sole proprietorship, or other legal entity. 3. Provide a description of all facilities where the Select Agent(s) will be used. Describe the procedures that will be used to monitor possession, use and transfer of Select Agent(s). Describe plans for appropriate biosafety, biocontainment, and security of the Select Agent(s). If you are responding to a specific funding opportunity announcement (e.g., PA or RFA), address any requirements specified by the solicitation. Reviewers will assess the information provided in this Section, and any questions associated with Select Agent research will need to 28

31 Field Name 14. Multiple PD/PI Leadership Plan 15. Consortium/Contractual Arrangements Instructions be addressed prior to award. Save this file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. For applications designating multiple PDs/PIs, a leadership plan must be included. A rationale for choosing a multiple PD/PI approach should be described. The governance and organizational structure of the leadership team and the research project should be described, including communication plans, process for making decisions on scientific direction, and procedures for resolving conflicts. The roles and administrative, technical, and scientific responsibilities for the project or program should be delineated for the PDs/PIs and other collaborators. If budget allocation is planned, the distribution of resources to specific components of the project or the individual PDs/PIs should be delineated in the Leadership Plan. In the event of an award, the requested allocations may be reflected in a footnote on the Notice of Grant Award. Save this file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. Explain the programmatic, fiscal, and administrative arrangements to be made between the applicant organization and the consortium organization(s). If consortium/contractual activities represent a significant portion of the overall project, explain why the applicant organization, rather than the ultimate performer of the activities, should be the grantee. The signature of the authorized organizational official on the SF424 (R&R) cover component (Item 18) signifies that the applicant and all proposed consortium participants understand and agree to the following statement: The appropriate programmatic and administrative personnel of each organization involved in this grant application are aware of the agency s consortium agreement policy and are prepared to establish the necessary inter-organizational agreement(s) consistent with that policy. A separate statement is no longer required. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. 16. Letters of Support Attach appropriate letters here from all individuals confirming 29

32 Field Name 17. Resource Sharing Plan(s) Instructions their roles in the project and rate/charge for consulting services. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. This section includes Data Sharing Plan, when applicable, and Sharing Model Organisms. These descriptions are not included in the Research Plan page limits. 1) Data Sharing Plan: Investigators seeking $500,000 or more in direct costs in any year are expected to include a brief 1-paragraph description of how final research data will be shared, or explain why data-sharing is not possible. Specific funding opportunity announcements may also require that all applications include this information regardless of the dollar level. Applicants are encouraged to read the specific opportunity carefully and discuss their data-sharing plan with their program contact at the time they negotiate an agreement with the Institute/Center (IC) staff to accept assignment of their application. (2) Sharing Model Organisms: Regardless of the amount requested, all applications where the development of model organisms is anticipated are to include a description of a specific plan for sharing and distributing unique model organism research resources or state appropriate reasons why such sharing is restricted or not possible. Note unlike the data sharing requirement above, this requirement is for all applications where the development of model organisms is anticipated. See Sharing Model Organisms Policy. If model organisms are not planned as part of the research proposal, omit this section. Save this information in a single file in a location you remember. Click Add Attachment, browse to where you saved the file, select the file, and then click Open. 18. Appendix Only one copy of appendix material is necessary. Use filenames for these attachments that are descriptive of the content. Use the add attachments button to the right of this field to complete this entry. A maximum of 10 PDF attachments is allowed. If more than 10 are needed, combine the remaining information into attachment #10. A summary sheet listing all of the items included in the appendix is encouraged, but not required. When including a summary sheet, it should be included as the first appendix attachment. New, resubmission, renewal, and revision applications may include the following materials in the Appendix: Publications No longer allowed as appendix materials 30

33 Field Name Instructions except in the circumstances noted below. Applicants may submit up to 3 of the following types of publications: o o Manuscripts and/or abstracts accepted for publication but not yet published: The entire article should be submitted as a PDF attachment. Manuscripts and/or abstracts published, but a free, online, publicly available journal link is not available: The entire article should be submitted as a PDF attachment. o Patents directly relevant to the project: The entire document should be submitted as a PDF attachment. (Do not include unpublished theses, or abstracts/manuscripts submitted (but not yet accepted) for publication.) Note, publications and/or abstracts in press should no longer be included in the appendix material. Include the URL or PMC submission identification numbers along with the full reference in the Bibliography and References cited section, the Progress Report Publication List section, and/or the Biographical Sketch section. Surveys, questionnaires, data collection instruments, clinical protocols, and informed consent documents. Photographs or color images of gels, micrographs, etc., are no longer accepted as Appendix material. These images must be included in the Research Plan PDF. However, images embedded in publications are allowed. For materials that cannot be submitted electronically or materials that cannot be converted to PDF format (e.g., medical devices, prototypes, DVDs, CDs), applicants should contact the Scientific Review Administrator for instructions following notification of assignment of the application to a study section. Applicants are encouraged to be as concise as possible and submit only information essential for the review of the application. Do not use the Appendix to circumvent the page limitations of the Research Plan. An application that does not observe these limitation will be withdrawn from review. These Appendix limitations may not apply to specialized grant applications. Request and follow the additional instructions for those applications. Specific appendix requirements may also be listed in a specific funding opportunity announcement. The Appendix will be sent only to certain members of the 31

34 Field Name Instructions Scientific Review Group who will serve as the primary reviewers of the application. 32

35 PHS 398 Cover Page Supplement OMB Number: Expiration Date: 9/30/ Project Director / Principal Investigator (PD/PI) Prefix: Middle Name: * Last Name: Suffix: * First Name: * New Investigator? No Yes Degrees: 2. Human Subjects Clinical Trial? No Yes * Agency-Defined Phase III Clinical Trial? No Yes 3. Applicant Organization Contact Person to be contacted on matters involving this application Prefix: Middle Name: * Last Name: McKinney Suffix: * First Name: Anita * Phone Number: Fax Number: anita.mckinney@osp.gatech.edu * Title: Contracting Officer * Street1: Street2: * City: 505 Tenth Street NW Atlanta County: Fulton * State: GA: Georgia Province: * Country: UNITED ST * Zip / Postal Code:

36 Proposal Submission The Submit button becomes active only after all mandatory elements of the grant application package have been completed including attachment of forms and mandatory fields. That means you ve completed the forms and moved them into the section entitled Completed Documents for Submission. There is a Check Package for Errors button to assist you with the preparation of this proposal, too. DO NOT submit it directly through Grants.Gov! When you ve completed your application and saved all the information. Then simply upload the file as an attachment via the Proposal File Upload System at See appendix for uploading information. Remember an OSP Routing Form needs to be completed and our deadlines for an electronic submission are: 5 business days prior to the deadline release the file to the contracting officer! After You Submit Your Application Via Grants.gov Once an application has been submitted via Grants.gov, several s are generated by Grants.gov and sent to the Contracting Officer named in the grant application indicating a Grants.gov tracking number that is assigned to the submission: 1) Submission Receipt: An is sent indicating your application has been received by Grants.gov and is currently being validated. 2) Submission Validation Receipt: An is sent indicating your application has been received and validated by Grants.gov and is being prepared for Grantor agency retrieval and review. 3) Grant Agency retrieval Receipt: An is sent indicating your application has been retrieved by the Grantor agency and is currently being reviewed. Once an application package has been successfully submitted through Grants.gov, all errors are corrected and an application has been assembled by the era Commons, PDs/PIs and AORs/SOs will have two business days to view the application. If everything is acceptable, no further action is necessary. The application will automatically move forward to the Division of Receipt and Referral in the Center for Scientific Review for processing after two business days. If, however, it is determined that some part of the application was lost or did not transfer correctly during the submission process, the AOR/SO will have the option to Reject the application and submit a Changed/Corrected application. The Reject feature should also be used if you determine that warnings are applicable to your application and need to be addressed now. Remember, warnings do not stop further application processing. If an application submission results in warnings (but no errors), it will automatically move forward after two business days if no action is taken. Some warnings may need to be addressed later in the process. PIs should work with their AOR/SO to determine when the Reject feature is appropriate. 33

37 Correcting Errors Prior to a specified submission date, applicants may make corrections and resubmit an application through Grants.gov. After a specified submission date, if applicants make corrections and resubmit, the application will be considered late. In this case, applicants must include a cover letter explaining the reasons for the delay. Please be aware of the distinction between errors and warnings. The word error is used to characterize any condition which causes the application to be deemed unacceptable for further consideration. Generally, errors will indicate significant inaccuracies, inconsistencies, omissions, or incorrect formatting that have been identified in the body of the application. Conversely, the word warning characterizes any condition that is acceptable, but worthy of bringing to the applicant s attention. It is at the applicant s discretion, whether a warning condition requires any action. PI Check Status - Errors Errors must be fixed for the submission to be accepted into the era Commons system. PI Check Status No Errors An application may be check once you see the term Transmittal Sheet in Action. Simply click on the link to the application. (If the viewed application is NOT acceptable, be sure to notify OSP to Reject the Application. A corrected application will need to be submitted via Grants.gov again.) 34

38 pp Next, click on the e-application link to view the image

39 Appendix 2.15 Submission, Review and Award Cycles The PHS submission, review, and award schedule is provided in Table For specialized grant applications, consult with the appropriate PHS agency prior to the preparation of an application. Note, Table references all funding mechanisms, regardless of which application is currently used. Some of the mechanisms listed continue to use applications other than the SF424 (R&R). Applicants should refer to the OER Electronic Submission of Grant Applications website: for details on mechanisms that have transitioned to electronic submission using the SF424 (R&R) application. Table Submission Dates, Review, and Award Cycles New Schedule effective January 3, 2007 Program Project Grants and Center Grants all P Series*** new, renewal, resubmission, revision* Research Grants R10, R18, R24, R25 new, renewal, resubmission, revision* Research-Related and Other Programs all S and G Series, C06, M01 new, renewal, resubmission, revision* Institutional Ruth L. Kirschstein National Research Service T Series (Training)** new, renewal, resubmission, revision* Research Grants R01 new Research Career Development all K Series new Research Grants R03, R21, R33, R21/R33, R34, R36 new RECEIPT CYCLE I January 25 Feb. 1) January 25 Feb. 1, March 1) January 25 Feb. 1) January 25 Jan. 10) February 5 Feb. 1) Feb. 12 Feb. 1) February 16 Feb. 1) RECEIPT CYCLE II May 25 June 1) May 25 June 1, July 1) May 25 June 1) May 25 May 10) June 5 June 1) June 12 June 1) June 16 June 1) RECEIPT CYCLE III September 25 Oct. 1) September 25 Oct. 1, Nov. 1) September 25 Oct. 1) September 25 Sept. 10) October 5 Oct. 1) October 12 Oct. 1) October 16 Oct. 1) 36

40 New Schedule effective January 3, 2007 Academic Research Enhancement Award (AREA) R15 new, renewal, resubmission, revision* Research Grants R01 renewal, resubmission, revision* Research Career Development all K Series renewal, resubmission, revision* Research Grants R03, R21, R33, R21/R33, R34, R36 renewal, resubmission, revision* New Investigator R01 resubmission* for those applications involved in pilot ONLY ( Small Business Innovation Research (SBIR), Small Business Technology Transfer (STTR) Grants R41, R42, R43 and R44 new, renewal, resubmission, revision* Individual Ruth L. Kirschstein National Research Service Awards (Standard) all F Series Fellowships**** new, renewal, resubmission* Conference Grants and Conference Cooperative Agreements R13, U13 new, renewal, resubmission, revision* AIDS and AIDS-Related Grants All of the mechanisms cited above new, renewal, resubmission, revision* RECEIPT CYCLE I February 25 (no change) March 5 March 1) March 12 March 1) March 16 March 1) March 20 (no change) April 5 April 1) April 8 April 5) April 12 April 15) May 1 (no change) RECEIPT CYCLE II June 25 (no change) July 5 July 1) July 12 July 1) July 16 July 1) July 20 (no change) August 5 Aug. 1) August 8 August 5) August 12 Aug. 15) September 1 (no change) RECEIPT CYCLE III October 25 (no change) November 5 Nov. 1) November 12 Nov. 1) November 16 Nov. 1) November 20 (no change) December 5 Dec. 1) December 8 December 5) December 12 Dec. 15) January 2 (no change) 37

41 New Schedule effective January 3, 2007 RECEIPT CYCLE I RECEIPT CYCLE II RECEIPT CYCLE III NOTE for all applications: RFAs and some PARs have special receipt dates indicated in the specific NIH Guide Announcement. * Change in Terminology: The move to electronic applications has brought a change in terminology. The new Grants.gov terminology (included in the table above) corresponds to the traditional NIH terms as follows: New = New Resubmission = A Revised or Amended application Renewal = Competing Continuation Continuation = Noncompeting Progress Report Revision = Competing Supplement **Institutional Research Training Grants (T32) are accepted by many NIH Institutes and Centers (IC) for only one or two of the dates. ***Program Project and Center Grants Applicants should check with individual ICs since some ICs do not accept P series applications three times a year. ****Individual Pre-Doctoral Fellowships (F31) for Minority Students and Students with Disabilities has special receipt dates. All AIDS and AIDS-related applications (no matter the type) are submitted on the AIDS and AIDS-related dates. Review and Award Cycles: Cycle I Cycle II Cycle III Scientific Merit Review Advisory Council Review June - July September - October October - November January - February Earliest Project Start Date December April July February - March May - June Note: Awarding components may not always be able to honor the requested start date of an application; therefore, applicants should make no commitments or obligations until confirmation of the start date by the awarding component. Application Assignment Information Competing grant applications that have been successfully submitted through Grants.gov (including correcting all errors and the grant application assembled by the era Commons system) will be processed through the Division of Receipt and Referral, CSR, NIH unless otherwise stated. The application will be assigned to an appropriate Scientific Review Group and awarding component(s). Assignment is based on the scientific content of the application using established referral guidelines. Business rule validations are conducted by the system as well as NIH staff. Assignment to Review Group. The Center for Scientific Review (CSR) will assign appropriately completed applications to the Scientific Review Groups (commonly referred to as SRGs or 38

42 study sections ) that will perform the scientific/technical merit review. The CSR lists the recurring review panels ( and you may suggest a specific group in the PHS 398 Cover Letter component. Assignment to Relevant Potential Awarding Component(s) (ICs). In addition, CSR will assign each application to the agency awarding component that is the potential funding component. When the scientific areas and the research proposed in a grant application are sufficiently relevant to the program responsibilities of two or more awarding components, CSR may assign your application to all such components. The component that has the most relevant program responsibility is designated as the primary assignee. The other components that have an interest in your application are designated as secondary assignees. If your application is eligible for funding and the primary assignee does not intend to make an award, the secondary assignees will be given the opportunity to do so. Although these suggestions will be taken into consideration, the final determination will be made by the agencies participating in this solicitation. After the submission date, usually within four (4) weeks, the PD/PI and the applicant organization will be able to access in the era Commons the application s assignment number; the name, address, and telephone number of the Scientific Review Administrator of the Scientific Review Group to which the application has been assigned; and the assigned Institute contact and phone number. Review outcome and other important information is also available in the Commons. If assignment information is not available in the era Commons within four weeks of the submission date, contact the Division of Receipt and Referral, Center for Scientific Review (CSR), National Institutes of Health, Bethesda, MD , (301) ; TTY (301) If there is a change in assignment, you will receive a notification. Applicant investigators must not communicate directly with any review group member about an application either before or after the review. Failure to strictly observe this policy will create serious breaches of confidentiality and conflicts of interest in the peer review process. From the time of assignment to the time the review of your application is complete, applicant investigators must direct all questions to the Scientific Review Administrator. This individual is in charge of the review group and is identified in the assignment notice that is mailed to you. Format Specifications for Text (PDF) Attachments Designed to maximize system-conducted validations, multiple separate attachments are required for a complete application. When the application is received by the agency, all submitted forms and all separate attachments are concatenated into a single document that is used by peer reviewers and agency staff. NIH and other PHS agencies require all text attachments to the PureEdge forms to be submitted as PDFs and that all text attachments conform to the agency-specific formatting requirements noted below. Failure to follow these requirements may lead to rejection of the application during agency validation or delay in the review process. 39

43 Font Use an Arial, Helvetica, Palatino Linotype, or Georgia typeface, a black font color, and a font size of 11 points or larger. (A Symbol font may be used to insert Greek letters or special characters; the font size requirement still applies.) Type density, including characters and spaces, must be no more than 15 characters per inch. Type may be no more than six lines per inch. Page Margins Use standard paper size (8 ½" x 11). Use at least one-half inch margins (top, bottom, left, and right) for all pages. Page Headers & Footers Do not include any information in a header or footer of the attachments. A header will be systemgenerated that references the name of the PD/PI. Page numbers for the footer will be systemgenerated in the complete application, with all pages sequentially numbered. Figures, Graphs, Diagrams, Charts, Tables, Figure Legends, and Footnotes You may use a smaller type size but it must be in a black font color, readily legible, and follow the font typeface requirement. Color can be used in figures; however, all text must be in a black font color, clear and legible. Grantsmanship Use English and avoid jargon. If terms are not universally known, spell out the term the first time it is used and note the appropriate abbreviation in parentheses. The abbreviation may be used thereafter. Page Limits Although many of the sections of this application are separate text (PDF) or PureEdge attachments, page limitations referenced in these instructions and/or funding opportunity announcement must still be followed. Agency validations will include checks for page limits. Some accommodation will be made for sections that when combined must fit within a specified limitation. Note that while these computer validations will help minimize incomplete and/or noncompliant applications, they do not replace the validations conducted by NIH staff. Applications found not to comply with the requirements may lead to rejection of the application during agency validation or delay in the review process. All applications and proposals for NIH and other PHS agency funding must be self-contained within specified page limitations. Observe the page number limitations given in Table Only in cases involving interdependent multiple subprojects (e.g., Program Projects and Multi-Center Clinical Trials) will the PHS accept applications that exceed the page number limitations. However, specific page number limits may apply to each subproject. For information pertaining to page number limits for such projects, contact the awarding component to which the application may be assigned. (See Table below) The page number limitations may also be different for other specialized grant applications (e.g., R03 and R21 applications). Consult and follow the additional instructions for those applications. Table: Page Limitations and Content Requirements 40

44 Section Page Limit Content Introduction - New applications - Resubmission applications - Revision applications Research Plan Sections 2-5 Not required/not to be submitted * * Some exclusions for renewal applications See Instructions Text including all figures, charts, tables, and diagrams. Sections 6-14 none Biographical Sketches 4 No more than four pages for each person listed as Senior/Key Persons. Appendix none No more than 10 publications (including accepted manuscripts); photographs (include a copy in the Research Plan); questionnaires; and other materials that do not photocopy well. PAs and RFAs Page limitations specified in the PA and RFA announcement in the NIH Guide take precedence. See specific instructions in PAs and RFAs published in the NIH Guide. Submissions! Note, on-time submission of an application is a 2-step process: 1) accepted by Grants.gov on or before deadline; and 2) verified within two business days of the image being available in Commons. Note, the image is available only once all errors are corrected. For this initial transition period, NIH provides a one week window for correction of any validation errors after initial submission. 41

45 NIH Announces Interim Changes to the PHS398 Application and Instructions Notice Number: NOT-OD Key Dates Release Date: April 7, 2006 Issued by National Institutes of Health (NIH), ( Body The PHS398 has been revised to incorporate a number of business process changes that have been implemented since the publication of the 9/2004 revision. This Guide Notice describes the particular business process change and the corresponding changes to the PHS398 application forms and instructions. Applicants should also review several other companion announcements: NOT-OD : NIH Announces Change in Business Process: Replacing the Principal Investigator Signature on Grant Applications, Progress Reports, and Prior Approval Requests with an Institutional Compliance Requirement NOT-OD : NIH/AHRQ Announce Change in Business Process Concerning era Commons Verification of Electronically Submitted Applications NOT-OD : NIH Announces Changes to the SF424 (R&R) Instructions NOT-OD : NIH Announces Interim Changes to the PHS2590 Noncompeting Progress Report Forms and Instructions. Revised forms (dated rev. 4/06) and instructions are available for immediate use and are required for paper applications being prepared for submission/receipt dates on/after May 10, After this date, applications submitted using previous versions of form pages that have been updated, may be delayed in the review process. Applicants Preparing Applications for Submission/receipt Dates Prior to May 10, 2006 : During the transition, form pages for both PHS398 (Revised 9/2004) and PHS398 (Interim Revision 4/2006) will be posted at: Use only form pages with the (Rev. 9/04) date. While you will continue to use the 9/2004 version of the 42

46 Instructions, do not use any of the form-page hyperlinks within those instructions; they will misdirect you to the new forms. Applicants Preparing Applications for Submission/receipt Dates On/After May 10, 2006 : During the transition, form pages for both PHS398 (Revised 9/2004) and PHS398 (Interim Revision 4/2006) will be posted at: Use only form pages with the (Rev. 4/06) date. Use the Instructions labeled Interim Revision 4/2006, which include hyperlinks to the appropriate new forms. Change in Business Process: Replacing PI Signature on the Application with an Institutional Compliance Requirement A new business practice is being implemented by replacing the signature of the Principal Investigator (PI) as a part of competing applications with an institutional compliance requirement where applicant organizations will capture and retain the PI signature as part of their institutional review/approval process. Effective with PHS398 applications prepared for submission/receipt dates on/after May 10, 2006, the signature of the Principal Investigator is no longer required as a part of a submitted application. Instead, a new compliance requirement is now implemented whereby the applicant organization agrees to secure and retain at the organization a written assurance from the Principal Investigator (PI) prior to submitting an application to the PHS. While this assurance is no longer required as part of the submitted application, it remains a compliance requirement. Therefore, organizations must retain a unique signature and date for each submitted application. This assurance must be available to the sponsoring agency or other authorized HHS or Federal officials upon request. Such an assurance must include at least the following certifications: (1) that the information submitted within the application is true, complete and accurate to the best of the PI's knowledge; (2) that any false, fictitious, or fraudulent statements or claims may subject the PI to criminal, civil, or administrative penalties; and (3) that the PI agrees to accept responsibility for the scientific conduct of the project and to provide the required progress reports if a grant is awarded as a result of the application. When multiple PIs are proposed in an application, this assurance must be retained for all named PIs. Specific Changes include: Face Page (Form Page 1 ): Has been revised to remove the PI signature item. Corresponding instructions have also been deleted. Checklist Form Page: Section II. Assurances has been revised to include the PI Assurance. Part III Policy/Assurances/Definitions: Section II/Assurances has been revised to include the PI Assurance as an institutional compliance requirement. 43

47 See NIH Guide Notice NOT-OD for additional information on this particular business process change. Change in Business Process: Including Publications as Appendix Material As described in NIH Guide Notice NOT-OD and clarified in Notice NOT-OD , effective for applications for submission/receipt dates of May 10, 2006 and beyond, the instructions for including paper publications as appendix material has changed. The new process is: Publications in press : Include only a publication list with a link to the publicly available on-line journal article or the NIH PubMed Central (PMC) submission identification number. Do not include the entire article. Manuscripts accepted for publication but not yet published : The entire article should be submitted and may be stapled. Manuscripts published but an online journal link is not available : The entire article should be submitted and may be stapled. Revised Requirements for Select Agent Research The requirements of the Research Plan have been revised to include a new section dedicated specifically to Select Agent Research. This new section (G. Select Agent Research) is only required when applicable. Additionally, the Resource Format Page instructions have been revised to request specific information on the biocontainment resources available when applicable. Finally, the Select Agent Research section in Part III Policy/Assurance/Definitions has been revised to include additional informational websites. Change in Business Process: Eliminating Biographical Sketch Subsection Limits The requirements for the biographical sketch have been changed to eliminate the 2-page subsection limit for sections A&B. The entire biographical sketch continues to have a 4-page limit (including the table at the top of the first page); however, the 2-page subsection limit for sections A&B has been eliminated. Removal of all Instructions and Data Requirements Specifically for Programs Transitioned to the SF424 (R&R) As NIH continues to transition all funding mechanisms to electronic submission and the SF424 (R&R) application, the data requirements and instructions to the PHS398 will be changed accordingly. With this revision, all 44

48 instructions and data requirements specific to SBIR and STTR applications (R43/R44 & R41/R42), AREA applications (R15s); and Conference applications (R13/U13s) have been removed. A consolidated list of changes to each Form or Format Page follows: Form Page 1 : Face Page (Rev. 4/06) New form page developed (Form Page 1-continued) to capture PI information for multiple PIs. Item 3h. The era Commons User Name (the unique name used to log into the system) is now a required for all PIs. Item 14, PI Signature Assurance has been removed. Form Page 2 (Rev. 4/06): Instructions for Key Personnel have been revised to incorporate multiple PIs. The Disclosure Permission Statement applicable for SBIR/STTR applicants has been removed Form Page 3 : Table of Contents (Rev. 4/06) The Table of Contents for the Research Plan has been revised to include 2 new sections Select Agents Research and Multiple PI Leadership Plan The Commercialization Plan item specific to SBIR/STTR applicants has been removed Form Page 4 : Detailed Budget (Rev. 4/06) The Personnel Section has been revised to replace Type of Appointment & Percent Effort columns with Person Month columns (calendar, academic, and summer) The budget item for SBIR/STTR Fee has been removed Form Page 5 : Budget for Entire Proposed Period of Support (Rev. 4/2006) The budget item for SBIR/STTR Fee has been removed Modular Budget Format Page (Rev. 4/06): Instructions have been modified for the Personnel Justification section to request effort devoted to the project using person months (calendar, academic, and summer) The budget justification section for SBIR/STTR Fee has been removed. 45

49 Resources Format Page (Rev. 4/06): Instructions revised to request information concerning biocontainment resources when Select Agent Research is proposed. Checklist Form Page (Rev. 4/06): All SBIR/STTR-specific data fields and information have been removed Section 2. Assurance has been revised to include new PI Assurance Key Personnel Format Page (Rev. 4/06) : The column requesting annual effort has been modified to now reflect person months (calendar, academic, summer) Personal Data Form Page (Rev. 4/06) : Instructions have been revised to cover the collection of this demographic information for all PIs. Biographical Sketch Format Page (Rev. 4/06): Instructions have been revised to eliminate the 2-page subsection page limit for sections A&B. The entire biographical sketch still has a 4-page limit, including the table at the top of page one. Other Support Format Page Example (Rev 4/06) : Instructional text and the example have been modified to reflect effort measurements in person months (calendar, academic, summer). 1. Will additional material be allowed before review but after the application is verified? ["Supplemental Information" new data, new publications, etc.] Yes. NIH is not changing that process. The applicant needs to contact the Scientific Review Administrator before submitting additional material. 2. What happens to page limits if the formatting changes when a PDF is generated? (Regarding the 25 page limitation )<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /> From the NIH FAQ... ( 46

50 ) NIH validations include checks for page limits. Some accommodation will be made for sections that when combined must fit within a specified limitation. For example, applicants are encouraged to construct the Research Plan as a single document, separating sections into distinct PDF attachments just before uploading the files. In this way the applicant can better monitor formatting requirements such as page limits. When validations for page limits are applied, the era Commons will make allowances for the white space created by breaking the text into separate files for uploading. Additional Information from NIH when asked for clarification... As to your questions, as the Q&A notes, our system validations accommodate for white space created when combining PDFs. So there is already some latitude built into the validation. The applicant may get a warning if they run slightly over, and then an error if it exceeds a particular threshold. Thresholds will be somewhat dependent on the particular program mechanism. (However I'm pretty certain that a few sentences over won't trigger even a warning.) Specific validations can be found in a (rather huge and technical) document found at: As for modifying the page limits, there is always discussion on various ways to improve an application; the size of the research plan is just one of many ideas that is discussed from time to time. But there are no concrete plans to change anything at this time. Should there be a change in that particular business process, it would be announced in a GUIDE notice. 3. Next, our faculty members are also concerned about the Research Plan 47

51 Component specifically the compliance information being broken out into multiple sections. Since much of the information will be a couple of sentences... Is there any plans to modify this section or can the faculty upload one file with all the sections on it in all of the sections? As for the separate uploads, we are taking advantage of technology to allow us to also bookmark the PDF grant images once the application is constructed by our system. The only way to accomplish the bookmarking is to have each of the sections uploaded separately. The bookmarking is particularly critical for our reviewers so that they can easily navigate to salient parts of an application. Since most reviewers receive only an electronic version of the applications to review, this technology has become key. At this time there is no plan to change this business model. Establishment of Multiple Principal Investigator Awards for the Support of Team Science Projects Notice Number: NOT-OD Key Dates Release Date: November 20, 2006 Issued by National Institutes of Health (NIH), ( Implementing the Multiple Principal Investigator Policy: Beginning with research grant applications submitted for February 2007 receipt dates, the NIH will allow applicants and their institutions to identify more than one Principal Investigator (PI). The Multiple PI option will be extended to most research grant applications submitted electronically through Grants.gov ( using the SF424 R&R application package. Grant applications that will accommodate more than one PI beginning in February include: R01, R03, R13/U13, R15, R18/U18, R21, R21/R33, R25, R33, R34, R41, R42, R43, R44, and C06/UC6 (see Some types of applications including individual career awards (K08, K23, etc.), individual fellowships (F31, F32, etc.), Dissertation Grants (R36), Director s Pioneer Awards (DP1), and Shared Instrumentation Grants (S10) will not accommodate more than a single PI. The restriction to a single PI will be described in announcements for those programs. 48

52 The NIH will extend the multiple PI option to most research grant applications when they transition to an electronic format. Some paper applications submitted on PHS 398 application forms also will allow inclusion of more than one PI, but only when the multiple PI option is clearly specified in the soliciting Request for Applications (RFA) or Program Announcement (PA). Other paper applications listing more than one PI may be delayed in the review process or returned to the applicant. The decision to apply for a single PI or a multiple PI grant will be the responsibility of the investigators and the applicant organization. Those decisions should be consistent with and justified by the scientific goals of the project. As described in the Background section below and on the Multiple Principal Investigator website at the NIH expects the availability of the Multiple PI option to encourage interdisciplinary and other team approaches to biomedical research. Features of the Multiple PI Option: The Multiple PI option will include the following features beginning in February 2007: o o Applications NIH Grant Applications Forms including the PHS 398 and SF424 R&R will accommodate more than one PI (see application forms at Applications that involve more than one PI must include a Leadership Plan that describes the roles, the responsibilities, and the working relationship of the identified PIs (see application instructions below) Principal Investigators All PIs are designated by the applicant institution (see definition of PI below) All PIs share the responsibility and authority for leading and directing the project (see definition of PI below) All listed PIs must be registered in era Commons with a PI role type. All listed PIs will have access to Status on the era Commons at The first PI listed must be affiliated with the institution submitting the application and will serve as the contact PI. The contact PI will be responsible for communication between the NIH and the rest of the leadership team. Being named contact PI does not imply any particular role within the leadership team. 49

53 o o o When requested by the grantee institution at the time of a non-competing application, another member of the leadership team may assume the role of contact PI. All PIs will be listed on summary statements All PIs will be listed on the Notice of Grant Award (NOGA) All PIs will be listed in CRISP (see Any requested allocation of funds to components of the project or the associated PIs must be included in the Leadership Plan (see below). If an award is made, the requested allocation will be acknowledged in the NOGA. Unless limited by a specific term of award, the acknowledgment of the requested allocation will not limit institutional authority to manage the funds nor will it impose additional prior approval requirements. The role type, Co-PI will not be used by the NIH New Investigator Policies NIH policies related to New Investigators will be applied to applications only when all PIs involved are classified as New Investigators (see The New Investigator Box on the application may be checked only when all PIs involved are classified as New Investigators (see instructions for Section 5.3 of the SF 424 R&R application at For the purpose of classification as a New Investigator, serving as a PI on a multiple PI grant will be equivalent to serving as a PI on a single PI grant. Review Criteria Standard NIH review criteria have been modified to accommodate both single PI and multiple PI applications (see below) Awards Involving More Than One Institution Awards involving PIs at different institutions will be managed using subcontracts until options involving linked awards have been developed. Features of the Multiple PI Option Still Under Development: The following Multiple PI options are still being developed or assessed: o o The ability to manage research projects using linked awards involving PIs located at more than one institution is being developed. The ability to recognize non-pi key contributors to the project is being developed. 50

54 o The desirability of formally apportioning funds under a grant to various components of a project or the PIs associated with those components will be assessed. Background and Purpose: The NIH announced a pilot initiative involving applications that permitted more than one PI on February 7, 2006 (see As indicated in that announcement, it is believed that the multiple PI option will offer a new and important opportunity for investigators seeking support for projects or activities that require a team science approach and which do not fit the single-pi model. The multiple-pi model is intended to supplement, and not to replace, the traditional single PI model. The goal is to encourage collaboration among equals when that is the most appropriate way to address a scientific problem. Although the number of applications submitted with more than one PI is expected to be relatively small compared with those that continue to use the traditional single-pi format, the ability to submit applications with more than one PI should encourage multidisciplinary efforts. This effort was undertaken in response to recommendations from the 2003 NIH Bioengineering Consortium (BECON) Symposium, Catalyzing Team Science (see as a 2005 Roadmap initiative to stimulate interdisciplinary science (see and in response to a directive from the Office of Science and Technology Policy (OSTP) issued to all federal research agencies in January 2005 (see ). The policies have been shaped by responses to a Request for Information (RFI) issued by OSTP (see and a second RFI issued by the NIH (see The NIH also conducted a pilot, receiving more than 60 applications that included multiple PIs in response to nine different Requests for Applications (RFAs) and Program Announcements (PAs). In addition, the NIH has held detailed discussions with the Council on Governmental Relations, the National Council of University Research Administrators, the Association of American Medical Colleges, the Federation of American Societies for Experimental Biology and other organizations to discuss the features and the policies associated with the multiple PI option. Findings from the Pilot: During the period of the pilot a number of applicants and peer reviewers were interviewed. Nearly everyone expressed support for the concept and offered constructive comments that have been incorporated into the instructions and review criteria shown below. During the Pilot, peer reviewers expressed the following reservations about applications that included teams of scientists: In some cases, applications described projects that included PIs that did not have an identified function within the leadership team based on their expertise and the nature of the project. In some cases applications identified PIs who seemed too junior to function in a leadership role and in other cases it appeared that senior PIs were included in what might be a considered a courtesy role. 51

55 In other cases, it appeared that the leadership team had been expanded only to justify additional salary support for involved personnel. In each of these cases, reviewers felt that the multiple PI approach detracted from the perceived merit of the application. Reviewers expressed hope that NIH would provide sufficient guidance to future applicants so that the decision to use a team approach was driven by the nature of the project and carefully justified in the Leadership Plan section of the application. Although the multiple PI option can facilitate interdisciplinary and other types of team research, PIs should take care to explain how the members of the leadership team will function on the project and how their inclusion will facilitate the accomplishment of the identified aims of the project. Based on information received, the NIH developed the following definitions and instructions for the initial roll-out of the multiple PI option. It is expected that the NIH will continue to learn about collaborative approaches. Future input will lead to additional refinement of instructions and policies. The following information has been incorporated into the templates for RFAs and PAs as well as the instructions for completing the PHS 398 and the SF424 R&R application forms. In addition, the standard five NIH review criteria have been modified to accommodate both single-pi and multiple-pi applications and are shown below. To adjust to electronic applications and the SF424 R&R, the PI is referred to as the Program Director/Principal Investigator (PD/PI) in these instructions to accommodate a broader range of application types. Additional information including Frequently Asked Questions (FAQs) has been updated on the NIH Multiple Pi website at NIH Definition of a Principal Investigator: The individual(s) judged by the applicant organization to have the appropriate level of authority and responsibility to direct the project or program supported by the grant. The applicant organization may designate multiple individuals as PD/PIs who share the authority and responsibility for leading and directing the project, intellectually and logistically. Each PD/PI is responsible and accountable to the applicant organization, or, as appropriate, to a collaborating organization, for the proper conduct of the project or program including the submission of all required reports. The presence of more than one identified PD/PI on an application or award diminishes neither the responsibility nor the accountability of any individual PD/PI. Deciding to Use the Multiple PI Option: The decision to apply for a single PD/PI or multiple PD/PI grant is the responsibility of the investigators and the applicant organization and should be determined by the scientific goals of the project. Applications for multiple PD/PI grants will require additional information, as outlined in the instructions. The NIH review criteria for approach, investigators, and environment have been modified to accommodate applications involving either a single PD/PI or multiple PD/PIs. When considering multiple PD/PIs, please be aware that the organizational structure and governance of the PD/PI leadership team as well as the knowledge, skills and experience of the individual PD/PIs will be factored into the assessment of the overall scientific merit of the application. Multiple PDs/PIs on a project share the authority and responsibility for leading 52

56 and directing the project, intellectually and logistically. Each PD/PI is responsible and accountable to the grantee organization, or, as appropriate, to a collaborating organization, for the proper conduct of the project or program, including the submission of required reports. For further information on multiple PD/PIs, please see Multiple PD/PI Leadership Plan: For applications designating multiple PD/PIs, a new section of the research plan, entitled Multiple PD/PI Leadership Plan (section 14 of the Research Plan Component in the SF424 R&R or Section I of the Research Plan in the PHS 398), must be included. A rationale for choosing a multiple PD/PI approach should be described. The governance and organizational structure of the leadership team and the research project should be described, including communication plans, process for making decisions on scientific direction, and procedures for resolving conflicts. The roles and administrative, technical, and scientific responsibilities for the project or program should be delineated for the PD/PIs and other collaborators. If budget allocation is planned, the distribution of resources to specific components of the project or the individual PD/PIs must be delineated in the Leadership Plan. In the event of an award, the requested allocation may be reflected in a footnote on the NOGA. Standard Review Criteria Modified to Accommodate Applications with and without Multiple PIs: Significance: Does this study address an important problem? If the aims of the application are achieved, how will scientific knowledge or clinical practice be advanced? What will be the effect of these studies on the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field? Approach: Are the conceptual or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? For applications designating multiple PD/PIs, is the leadership approach, including the designated roles and responsibilities, governance and organizational structure consistent with and justified by the aims of the project and the expertise of each of the PD/PIs? Innovation: Is the project original and innovative? For example: Does the project challenge existing paradigms or clinical practice; address an innovative hypothesis or critical barrier to progress in the field? Does the project develop or employ novel concepts, approaches, methodologies, tools, or technologies for this area? Investigators: Are the PD/PI(s) and other key personnel appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the PD/PI(s) and other researchers? Do the PD/PI(s) and the investigative team bring complementary and integrated expertise to the project (if applicable). 53

57 Environment: Do(es) the scientific environment(s) in which the work will be done contribute to the probability of success? Do the proposed studies benefit from unique features of the scientific environment(s), or subject populations, or employ useful collaborative arrangements? Is there evidence of institutional support? Inquiry For additional information please visit the Multiple Principal Investigator website at and feel free to send to 54

58 New Limits on Appendix Materials for All NIH/AHRQ/NIOSH Grant Applications Beginning with Receipt Dates On or After January 3, 2007 Notice Number: NOT-OD Key Dates Release Date: November 17, 2006 Effective Date: January 3, 2007 Issued by National Institutes of Health (NIH), ( Agency for Healthcare Research and Quality (AHRQ), National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (NIOSH/CDC; The purpose of this Notice is to announce a change in policy limiting Appendix materials that may be submitted with grant applications to NIH/AHRQ/NIOSH. The goal of changing the guidelines for grant application Appendix materials is to encourage applications to be as concise as possible while containing the information needed for expert scientific review. These changes take advantage of electronic access to many publications and should make application preparation and handling easier for both applicants and reviewers. It is important to note that the Appendix may not be used to circumvent the page limitations of the Research Plan. The following changes apply to applications in response to any funding opportunity announcement (FOA) with submission/receipt dates on or after January 3, Information that May Be Included in the Application Published manuscripts and/or abstracts that are publicly available in a free, online format may be referenced in the application. These publications may not be included in the appendix. URLs or NIH PubMed Central (PMC) submission identification numbers may be included along with the full reference in the Bibliography and References Cited section (SF 424RR)/Literature Cited (PHS 398) section, the Progress Report Publication List section and/or the Biographical Sketch section. While there is no limit to the number of URLs or PMC submission identification numbers that can be cited, applicants should be both judicious and concise. 55

59 Applications requiring electronic submission on the SF424 (R&R) may include graphic images of gels, micrographs, photographs, etc. in the Research Plan PDF; however these images may not be included in the Appendix (except when part of a qualifying publication). See the SF 424 (R&R) Application Guide for guidance as to size and resolution of images. Materials Allowed in the Appendix Publications: Applicants may submit up to 3 of the following types of publications. Any exceptions will be noted in specific FOAs. o o o Manuscripts and/or abstracts accepted for publication but not yet published. Published manuscripts and/or abstracts only when a free, online, publicly available journal link is not available. Patents materials directly relevant to the project. Other: Surveys, questionnaires, data collection instruments, clinical protocols, and informed consent documents may be submitted in the Appendix as necessary. Paper PHS398 applications only may include full-sized glossy photographs of material such as electron micrographs or gels in the Appendix; however, an image of each (may be reduced in size but readily legible) must also be included within the page limitations of the Research Plan. Format of Appendix Materials For electronic submission using the SF 424 (R&R) forms and Grants.gov, Appendix materials must be submitted in PDF format. For paper submission using the PHS 398, Appendix materials may be submitted in paper format; five collated sets are needed. Applicants are encouraged to send Appendix materials submitted with paper PHS 398 applications on a CD in PDF format in lieu of the five collated sets. See application instructions for details on preparing CDs. Only a single CD need be sent. 56

60 For materials that cannot be submitted electronically or materials that cannot be converted to PDF format; (e.g., medical devices, prototypes, DVDs, CDs), applicants should contact the Scientific Review Administrator for instructions following notification of assignment of the application to a study section. If the SRA is listed in the FOA, they should be contacted in advance to address acceptability of materials. Funding Opportunity Announcement (FOA) Details Any FOAs that currently disallow publications in the Appendix will continue to do so. FOAs currently allowing more than three publications will only allow three for receipt dates on or after January 3. FOAs allowing fewer than three publications will now allow three. In the case of multi-project applications up to three publications will be allowed for each project. FOAs may have additional appendix requirements specified other than publications. In these cases, follow the FOA instructions, which prevail. Inquiry Inquiries regarding this Notice should be directed to: Grants Info Office of Extramural Research National Institutes of Health Phone: TTY: grantsinfo@nih.gov 57

61 Change in Business Process: Measuring Effort Devoted to Projects Transitioning to the SF424 Research and Related (R&R) has introduced a new business practice for measuring effort devoted to a project person months. Personnel working on projects now indicate effort by indicating the number of calendar, academic, and/or summer months. To keep a consistent business practice in place for all applications, regardless of which set of forms is being used, the PHS398 has also been revised to reflect this new effort measure. Specific changes include: Form Page 4 (Detailed Budget Page): The Personnel section of the budget has been revised to replace Type of Appointment and Percent Effort, with the 3 columns of person months calendar, academic, and summer. Key Personnel Format Report: This format page has been revised to replace the Percent Effort column with the 3 columns of person months calendar, academic, and summer. Modular Instructions, Budget Justification: The Personnel Budget Justification instructions have been revised to reflect person months (calendar, academic, and summer) as the measure for effort. Other Support Instructions: The Other Support instructions have been revised to reflect person months (calendar, academic, and summer) as the measure for effort. Note, Other Support information continues to be required as a Just-In-Time submission. General Instructions Changes: Changes have been made throughout the instructions to include appropriate guidance for measuring effort in terms of person months. FAQ - Person Months - Excel Spreadsheet to assist with conversion. 58

62 Grants.gov Georgia Institute of Technology 9/2006 Section I: Login In order to submit Grants.gov files to OSP, we request that you use the proposal file upload system which is located at instead of ing them to us. Login using your GT Account (aka Kerberos) login. Click on Login. Click on the Upload Proposal link. If you are the PI, click on Yes and the system will then jump to the next section on uploading!

63 Grants.gov Georgia Institute of Technology 9/2006 If you are not the PI click on NO. Next, type in as much of the PI s last name in the text box and then click on continue. The system will then display a list of names that match the information. Click on the appropriate name and then click on Continue. The next screen is the Upload screen.

64 Grants.gov Georgia Institute of Technology 9/2006 Section II: Upload PI INFORMATION: The PI s information should be pre-populated on this screen. [If it isn t do not type it in. If you do, you will receive error messages when trying to upload.] OTHER AGENCY and CONTRACTING OFFICER INFORMATION: Next, click on the drop down box to choose the Agency and Contracting Officer (CO) to submit the proposal. The CO s information will then populate the section. [This is a REQUIRED field.] NOTE: Fields marked with a red (*) asterisk is required fields.

65 Grants.gov Georgia Institute of Technology 9/2006 OTHER PROPOSAL UPLOAD INFORMATION: Announcement Link Announcement Link is a required field. Please include the solicitation number, Funding Opportunity Number, Request for Proposal, Program Announcement or Broad Agency Announcement for the proposal being submitted. You may also include the URL to the program announcement. If it is an unsolicited proposal, put unsolicited proposal the text box. NOTE: Fields marked with a red (*) asterisk is required fields. Additional Addresses If a PI wants additional folks to be notified of the submission to OSP, include their s in the Additional Addresses. CFDA If the Catalog of Federal Domestic Assistance Numbers (CFDA) is known, please include it. Comments for GTRC Include any additional comments for the Contracting Officer regarding the proposal. PROPOSAL DOCUMENTS to UPLOAD At least one attachment is required for the submission to work properly. IMPORTANT! Files uploaded with the same name by the same PI (or on behalf of the same PI) will be overwritten. If you wish to preserve the earlier version be sure to change the file name! NOTE: Fields marked with a red (*) asterisk is required fields.

66 Grants.gov Georgia Institute of Technology 9/2006 Upload the files to submit to your Contracting Officer. Click on Browse, then navigate to the file and select the file and click open (or double click). Note: There is a ½ GB limitation for an individual file or the total amount of all of the files that are uploaded at one time. The file location will then populate this field. Add up to two additional files. Click on Submit. You will then receive a message indicating whether or not the file was uploaded. If it was successful, the PI and the Contracting Officer and any additional s list on this page will be notified of the uploaded file. Click Logout to do so. Questions: Contact grants.gov@osp.gatech.edu or contact your Contracting Officer.