How to Conduct Robust Root Cause Investigations for CAPA (Corrective and Preventive Action)
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1 How to Conduct Robust Root Cause Investigations for CAPA (Corrective and Preventive Action) Celebrating 50 YEARS March 27-28, 2017 Burlingame, CA Course Topics Include: Describing the Problem / Deviation Gathering Pertinent Facts Tools and Techniques to Identify Possible Causes Determining Effective Corrective/Preventive Actions How to verify the Corrective/Preventive Actions Real Case Studies & Break Out Sessions course description One of the most common FDA 483 and Warning Letter citations continues to be inadequate investigations. The FDA uses the investigation reports and investigation trends to identify potential quality problems in all areas of the company. Ultimately, inadequate investigations can lead to 483 citations, Warning Letters, release of sub-standard product, or product recall. Furthermore, costly and time-consuming system remediation may be required. Having a procedure on Deviation Investigations is not enough. It is the content and conclusions of the investigations themselves that truly count. Doing a proper root cause analysis, gathering evidence and ensuring a sustainable corrective action is key to a proper deviation investigation. This seminar will help attendees understand the fundamental investigation steps and skill sets. Key focus will be placed on identification and initial reporting of deviations, fact/evidence gathering, and arriving at the correct root cause and CAPA. The importance of investigation planning, critical thinking skills and effective preventative action plans will also be discussed. Root Cause Analysis (RCA) is an important technique practiced by many successful companies. It is used to determine the Corrective Action and Preventive Action CAPA procedures that are mandatory for the Quality Management Systems (QMS). This training improves the way you analyze, document, and verify the root causes of a problem so that you can prevent their recurrence. This course will also include discussions on proper CAPA system maintenance, documentation of the Corrective and Preventative Actions and developing a robust CAPA plan. It will give tips on how to develop CAPAs pertaining to longer term projects and ensure they stay on track. SAVE $200-Register & Pay by February 13
2 who should attend This is an informative and interactive seminar for professionals in the pharmaceutical, biological, and medical device industries who conduct deviations, Root Cause Analysis (RCA) and Corrective and Preventive Action (CAPA) investigations, especially for professionals in the following disciplines: Quality Control Analysts R&D Quality Assurance Manufacturing Product/Process Development Engineering learning objectives Upon completion of this course, you will be able to: Discuss what to do when problems occur Outline the requirements of the Deviation and procedure including the deviation report Choose the most appropriate Root Cause Analysis methods for the situation Discuss how to conduct the deviation and the tools to be used in the process Review and discuss an example deviation using the tools suggested Outline the requirements of the CAPA process and procedure including building a CAPA file Establishing a CAPA plan: project summary, individual responsibilities and expected completion dates Management and Oversight of the CAPA system and its documentation course outline First Day 8:00 a.m.: Registration/Continental Breakfast 8:30 10:00 a.m.: Review of Learning Objectives/ Introduction Review of FDA and Regulatory Requirements for Investigations, Root Cause and CAPA FDA and EU requirements What is the definition of a deviation? Types of Deviations Identification of Deviations Classifications of deviations Break out session Classifying Deviations 10:15 12:00 noon: Conducting the Investigation Interviews dos and don ts Source Documents/Evidence Break out session Using tools to conduct the investigation 1:00 2:30 p.m.: Determining Root Cause and Corrective/ Preventative Action Methods of Root Cause Review of case studies using root cause Break out session Using Root Cause Tools 2:45 5:00 p.m.: Key Elements of the Investigation Report Documentation Product Impact Training Expectations from Regulators Break Out session Finding the errors in real life industry deviations Second Day 8:00 9:30 a.m.: Definition of a CAPA When a CAPA is needed Development of the essential pieces of a robust CAPA plan Break out session Determining which deviations require a CAPA 9:45 12:00 noon: Establishment of the CAPA Plan Project Summary development Responsibilities of individuals involved Establishing Completion Dates Creating meaningful effectiveness checks Break out session What is an effective CAPA? 1:00 3:30 p.m.: Management of the CAPA System Maintaining proper documentation of the CAPA plans Ensuring CAPA plans are progressing Proper close out of CAPA plans Break out session writing your own CAPA Assessment Opportunity course director Louis Angelucci is a pharmaceutical professional with over 20 years experience in Quality Assurance, Quality Control, Regulatory Affairs, Validation, consent decree remediation as well as cgmp Compliance in the Medical Device and Pharmaceutical industries. He has worked for several wellknown companies including Johnson & Johnson, Bristol-Meyer Squibb, Pfizer, Schering Plough and Merck. His experience has been either as a direct employee or as a contracting consultant while employed at Foster Wheeler and Aker Kvaerner. As a consultant Mr. Angelucci has worked at various project locations domestically and in Europe and Asia. Mr. Angelucci is a degreed engineer with two master s degrees in engineering, holds industry certifications with ASQ as a CQE, CQA and CPGP. He is currently the ASQ Philadelphia chapter Education Chair. In addition, he holds a PMP certification through the Project Management Institute. He has published numerous articles on the subjects of Validation and compliance and has been a speaker to industry groups such as ISPE, IVT, DIA, PDA and ASQ. For assistance contact Customer Service at 1/ or us at: info@cfpa.com For More Information or to Register Go to
3 course location This course will be held in the San Francisco Bay area. Specific hotel information will be sent to you in your final confirmation package which will be ed to you approximately three (3) weeks prior to the course start date. Please note that participants must make their own hotel reservations; the cost of the hotel accommodations is not included in the course fee. We recommend that travel/hotel arrangements not be made until final confirmation package is received. Easy access to downtown San Francisco Bay Area attractions accreditations/recertifications for this course The Center for Professional Advancement (CfPA) has been approved as an Accredited Provider by the International Association for Continuing Education and Training (IACET), Sunset Hills Rd., Suite 130, Reston, VA In obtaining this approval, CfPA has demonstrated that it complies with the ANSI/IACET Standards which are widely recognized as standards of good practice internationally. CfPA is therefore authorized to offer IACET CEUs for its programs that qualify under the ANSI/IACET Standards. CEUs will be awarded for participation in CfPA s courses at the rate of.1 CEU per contact hour upon successful completion of the entire course and 70% accuracy in the required Learners Assessment. This course offers a total of 12 contact hours, or 1.2 CEUs. SME Certified Manufacturing Engineers (CMfgE) and Technologists (CMfgT) may earn 12 recertification credits for attending this program. Certification is valuable to everyone in industry. It is a recognized method of maintaining knowledge and skills in your field. For complete details on SME Certification, contact service@sme.org One SME Drive, Dearborn, MI 48121, This course has been approved by the AACE International Certification Board/The Association for Total Cost Management for 1.2 credits toward meeting the continuing education requirements for recertification as a Certified Engineer/Certified Cost Consultant. who we are Celebrating 50 Years The Center for Professional Advancement (CfPA) is the largest accredited technical training organization in the world with a curriculum of approximately 450 short courses in 15 industries including Pharmaceutical, Biotechnology, Medical Device, Chemical, Cosmetics, Food and more. Since our founding in 1967, we have successfully trained nearly a half million people worldwide in topics ranging from basic and introductory concepts to new advances and cutting-edge technology, and current U.S. and European regulations. CfPA courses are offered in a variety of formats to fit you or your company s training needs: In Person: Away from responsibilities, participants are immersed without distraction Client Site: Training at your site and at your convenience. For further information, please contact Client Site Programs: +1/ , ext or clientsite@cfpa.com Online: A convenient and cost-effective way to experience our accredited training. For a list of upcoming courses visit we also offer Client Site: Training at your site and at your convenience. This course and any of our other courses are available to be customized and brought to your location. For more information visit Online Training: A convenient and cost-effective way to experience our accredited training. Easily access the knowledge you need through the Internet. For a list of upcoming courses visit tuition Early Bird Save $200 (Must register and pay by February 13, 2017) $1970 Regular Tuition $2170 Group Discount: Register 2 or more from the same company, at the same time, for this course and receive a 10% discount off each registration. Tuition payable in US funds net of all charges includes continental breakfast, luncheon, breaks and course notes. Note: Payment is due 2 weeks prior to course or at time of registration. For assistance contact Customer Service at 1/ or us at: info@cfpa.com For More Information or to Register Go to
4 how to register Online: enter Course ID# into Search. Click Register Now button. Group Rates Available: Save 10% on 2 or more attendees. Call Customer Service at or info@cfpa.com Fill out the registration form and it to: info@cfpa.com registration form How to Conduct Robust Root Cause Investigations for CAPA course id# 2089 /course offering# CA2089 instructions: Please complete Registrant Information, Course Information and Payment Sections. Submit one form per individual registrant. o Check here if group discount applies (two or more enrollments for the same course, from the same company) All fields MUST be completed in order for registration to be accepted. registrant information Registration Type: o In Person Attendee o Virtual Attendee (Live or Recorded) Prefix: o Ms o Miss o Mrs o Mr o Dr o Prof First Name Last Name Designation (i.e.phd, Jr) Address Alternate (copy sent here as well) Title Your position in the organization is (please check one) o Corporate o Line Operational o Managerial/Supervisory o Staff o Consultant Your primary job function is (please check one) o Clinical Practice o Project Management o Design Engineering o Quality Control Assurance o Environmental Safety o Research & Development o Legal or Regulatory Affairs o Technical Information Services o Manufacturing & Operations o Training and/or Education o Marketing or Sales o Other *Primary industry that best describes your area of interest (select maximum of 2) o Analytical Chemistry o Biopharmaceuticals/ Biotechnology o Chemical/ Process Engineering o Clinical/ Non-Clinical o Cosmetics/ Personal Care/ Household Products o Environmental and Safety Technology o Mechanical/ Design Engineering o Medical Devices/ Diagnostics o Packaging Technology o Petroleum Technology o Pharmaceutical Technology o Technical/ Project Management o Food Technology
5 contact information Company Name Address Zip/Postal Code City Country Phone Fax course information Course Title Course ID#/Offering# Tuition Tuition *How did you hear about us? o o Postcard o Colleague o Google Search o Social Media o Trade Show o Advertisement o Course Director o Course Brochure o Other discount code Discount Code payment information o Credit Card o Visa o Mastercard o American Express o Discover Card #: Exp. Date: Security Code: Cardholder Name: Signature: Billling Addess (if different from above) Address Zip/Postal Code City Country o Wire Transfer o Purchase order (PO# if applicable ) o Send Invoice o Check: Payable in US funds to: The Center for Professional Advancement terms and conditions Payment: Tuition payable in US funds net of all charges. Payment is due at time of registration or upon receipt of invoice. If payment has not been received two weeks before the course, a credit card will be required to guarantee registration. Discounts/Rates: To receive the Early Bird tuition rate, payment is required at time of registration and/or BEFORE early registration tuition expires or the regular tuition rate will apply. The Virtual Attendee Option does not qualify for Early Bird pricing. If choosing invoice/wire transfer, payment must be received prior to expiration of early registration tuition or the regular tuition rate will apply. All tuition prices are a per person rate. To qualify for the Group Rate discount, registration must be for two or more enrollments registering at the same time, from the same company, for the same course. Please note: Group Rate Discount cannot be combined with any other discount. Multiple discounts not applicable. Cancellations/Substitutions/FEES: ALL cancellations must be in writing and ed to: info@cfpa.com. All cancellations are subject to a $ cancellation fee. Applicants may cancel up to four (4) weeks prior to the course start date for a refund less cancellation fee. Applicants that cancel less than four (4) weeks prior to the course will be issued a credit less cancellation fee that can be used towards a future course up to one year from the date of issuance. If you do not cancel and do not attend you are still responsible for the full payment. If for any reason, CfPA decides to cancel this course, we are not responsible for airfare, hotel or other costs incurred by the registrant. Program content, schedule and instructors are subject to change without notice. Substitutions are permitted at any time, must be in writing and ed to Customer Service at info@cfpa.com. Confirmation Letters: Before each course begins, all registrants will receive written Final confirmation including detailed information regarding course location VIA . We recommend that travel/hotel arrangements not be made until final confirmation package is received. If confirmation is not received two weeks prior to the course please contact Customer Service at info@cfpa.com. Course photography / video: By registering and attending a CfPA course, you agree to have your photograph and/or video taken at the course venue, and you do not have any objections to CfPA using these photos and/or videos for marketing or any other CfPA Course and/or promotional purposes. You agree to release CfPA from any kind of claims arising out of copyright or privacy violations. All questions regarding this matter should be sent to Customer Service at info@cfpa.com. Please note: English will be used in all lectures and course notes. For questions/more information contact Customer Service at or info@cfpa.com. o I have read and agree to CfPA s Terms and Conditions
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