Experiences from Peru; What have we learned? Dr. Martin Yagui Moscoso

Transcription

1 Experiences from Peru; What have we learned? Dr. Martin Yagui Moscoso

2 1. PERU Area: 1,285,215 Km Total population: 28 millions Average life expectancy:69years Population living in poverty: 54% TB incidence: 108 x 100,000 MDR TB among new patients: 3% National HIV prevalence: 0.6% TB among HIV patients: 30% HIV among TB patients: 3%

3 1. Health Services Health Services Hospitals Health Centers Post Centers TOTAL Number 486 1,778 5,237 7,501

4 2. Tasa de Morbilidad e Incidencia de Tuberculosis Perú

5 3. TB transmission in Health services in Peru 2000: A Study in Callao-Peru using tuberculin skin Test (TST) between residents measured incidence of TST conversion Of 98 residents that had been evaluated, 59% had a positive TST before the study Of 36 residents that were initially negative TST, 6 converted to positive TST (Annual rate of TST conversion: 17%) Bonifacio N.; Saito M., Gillman R et al. High Risk for Tuberculosis in Hospital Physicians, Peru. Letter in Emerg Infect. Dis. 8:

6 TB outbreak in Health services in Peru Outbreak in Almenara Hospital in health workers with TB suspects. TB incidence 1994: 167 x 100,000 TB incidence 1997: Laboratory: 6977 x 100,000 Medicine: 932 x 100,000 Alonso Echanobe J et al. Transmision of M Tuberculosis in Heahthcare workers University Hospital in Lima Peru Clin Infec Dis 2001;33:

7 TB outbreak in Health services in Peru 36 health workers had TB confirmed Multivariate analysis: independent risk factor for TB infection in laboratory health workers was the use of common areas Alonso Echanobe J et al. Transmision of M Tuberculosis in Heahthcare workers University Hospital in Lima Peru Clin Infec Dis 2001;33:

8 Susceptibility and resistance of M. tuberculosis in Health workers. Peru Results Pan-susceptible MDR Poli or monoresistance Non viable or contaminated TOTAL # %

9 4. Chronology of IC in Peru Beginning of Activities of General IC The first guideline of TB IC in Peru The first course for engineers/ Updated TB Guidelines Organization and improvement of NTP/ Biosafety Beginning of the TB IC trainings TB IC plans In 10 Health Centers and hospitals Global Fund finance TB IC Plans in 18 hospitals

10 5. Peruvian Guidelines of IC 1998: the first Infection Control Guidelines (in general): Surveillance of Nosocomial infections (NI) Control and prevention of NI Sterilization Hospital Solids residues

11 5. Peruvian Guidelines of TB-IC 2002: specific guidelines for TB-IC Isolation Guideline (2002) TB Infection Control for Health establishments: Training module (2004) Manual de doctrina de TB (2006)

12 6. Training in Infection Control : 70 hospitals were training in surveillance of Nosocomial infections, control and prevention, isolation and sterilization. More than 2000 health workers were training in general and specifics aspects of Infection control.

13 6. Training in Infection Control 2002: Training in TB-IC for health workers of Lima and Callao in courses to: Doctors and nurses of TB programs Laboratorists Hospital directors Doctors and nurses of emergency, ICU and medicine departments Engineers and architects

14 6. Training in Infection Control The content of those courses include: general concepts about TB transmission, administrative controls, environmental controls (natural and mechanical ventilation, UV Light, HEPA filters) and respiratory protection (fit test) Time: 3 or 4 days.

15 7. Implementation of TB-IC Plans TB-IC Plans were subsequent to the training courses. We help to participants to develop a TB-IC Plan in the last day of the course and then select the best TB-IC Plan

16 7. Implementation of TB-IC Plans Criteria for selection are: 3 controls (administrative, environmental, rp) political commitment of authorities of the hospital Health services that have high rates of TB and MDR Amount of money for each TB-IC Plan: Health centers: $5000 Hospitals: $15,000 20,000

17 8. Example of TB-IC Plans in Lima Before - After

18 9. Biosafety in Mycobacterium laboratory 1996: NHI of Peru has developed the norms of biosafety for TB laboratories 2006: these norms were updated

19 9. Biosafety in Mycobacterium laboratory With the support of the State Laboratory of Massachusetts courses have been developed to form certifiers of biosafety cabinets TB Laboratory network in Peru: 60 laboratories process cultures 6 laboratories process DST

20 9. Biosafety in Mycobacterium laboratories Since 2004 were remodeled and/or built intermediate laboratories for processing Rapid DST (Griess), conventional DST and cultures in Lima with the followings criteria: More than 12 air exchange/hour Negative pressure Functional distribution of the areas

21 10. Future activities in TB-IC The Global Fund TB Project has planned Infection Control activities for 18 hospitals at national level, this includes: Trainings for health workers in 18 hospitals Financing the implementation of 18 Infection Control Plans.

22 11. Infection Control in Latin America Since 2002, PAHO promoted some activities on General Infection Control this included the following: Elaboration of protocols (cost, supervision) Technical assistance Visits of supervision to hospitals

23 11. Isolation Rooms in Latin America hospitals 2006: evaluated 31 hospitals in 5 countries of Latin America. We used a Rapid Guideline of PAHO for IC Only 7 hospitals had respiratory isolation room (23%)

24 11. TB Infection Control in Latin America Courses in Bolivia, Paraguay and Ecuador during Approximately 40 participants for each course These courses included doctors, nurses and laboratorist of referal hospitals of each country

25 11. TB Infection Control in Latin America Included trainers from Peru and CDC Practice include: Administrative controls: identify risk areas for TB transmission Environmental controls: evaluation of natural and mechanical ventilation, measure of air flow and # of air exchange, etc Respiratory protection: Fit test

26 12. Lessons learned: Guidelines The existence of local and national guidelines on general aspects of Infection Control facilitates the introduction of TB-IC measures

27 12. Lessons learned: Guidelines It's important to be careful in adopting recommendations of other countries with different prevalence of TB, more resources, etc.

28 12. Lessons learned: Elaboration and implementation of TB-IC Plans In many hospitals aspects of environmental controls and respiratory protection are prioritized neglecting the implementation of administrative controls.

29 12. Lessons learned: Training Frequent rotation of health workers forces to National TB program to have constant trainings in infection control

30 12. Lessons learned: Training It is important to include to engineers and architects who work in health services in these trainings.

31 12. Lessons learned: donors National TB programs must be able to supervise construction or remodeling TB areas (inpatient, laboratories, etc) not to increase the risk of transmission Donors not necessarily know about IC

32 Acknowledgements Peruvian National Tuberculosis Program Peruvian National Institute of Health CDC PAHO/WHO Socios en Salud Harvard Medical School Brigham and Women s Hospital Massachusetts State Laboratory Institute

33 THANKS Martin Yagui Moscoso, MD