Searching for Clinical Guidelines, Algorithms, and Mixed Methods Studies: What s Wrong with PICO?

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1 Searching for Clinical Guidelines, Algorithms, and Mixed Methods Studies: What s Wrong with PICO? Janice M. Jones, PhD, CNS, RN University at Buffalo School of Nursing Buffalo, NY 43 rd BIENNIAL STTI CONVENTION

2 Disclosures Janice M. Jones, University at Buffalo, School of Nursing Objectives Assess the pros and cons of using the PICO format in conducting a search for evidence-based practices. Identify alternative search strategies in the retrieval of evidence, clinical guidelines, and clinically relevant evidence-based algorithms. The author declares no Conflict of Interest of any sort related to this presentation. The author is receiving no sponsorship or commercial support related to this presentation. 43 rd BIENNIAL STTI CONVENTION

3 PICO(T) format 4 dimensions P = Population of interest I = Intervention C = Comparison O = Outcome T = Time (optional) Specificity of keywords forms the basis for the literature search.

4 PICO Advantages and Challenges Promoted as the best method to formulate a clinical question for specific patient problems and populations. - Known interventions - Clear outcomes What about 3 or 4 comparisons? Reduce stress and BP: mediation, yoga, prayer, exercise - Able to do this in most databases Less useful for clinical guidelines, algorithms, mixed methods studies or qualitative research Adapt these clinical questions into PICO questions?

5 Evidence-Based Clinical Guidelines More prolific in the literature Generally comprised of a variety of evidence-based resources Meta-analyses RCTs Experimental and quasi experimental studies Published by notable organizations such as American Heart Association, Society for Gastroenterologists Example: A.S.P.E.N. Enteral Nutrition Practice Recommendations: acceptable residual volumes for ICU patients receiving enteral feedings

6 PICO lends itself to one or two aspects of the guidelines but not in total. C = Comparison Use guidelines or not Difficult to search in CINAHL or PubMed

7 Evidence-Based Bundles and Algorithms Need to know that a bundle exists e.g. ventilator associated pneumonia (VAP) background information I = use of VAP bundle gold standard C = not use the VAP bundle Search term bundle no results Search term algorithm no results PubMed, some results CINAHL

8 Qualitative and Mixed Methods Research PICO lends itself well to quantitative data PIO may or may not lend itself to qualitative data P = population I = interpretation or issue of interest O = outcome SPIDER method: Sample Phenomenon of Interest Design Evaluation Research Type Smith, D., & Booth, A. (2012). Beyond PICO: The SPIDER tool for qualitative evidence synthesis. Qualitative Health Research, 22(10),

9 Quality Improvement Studies Process improvement questions. Quality assurance or quality improvement questions. Healthcare delivery science questions. All are based on some level of evidence. Quality of Care or Donabedian model - Structure Process Outcomes Plan Do Study/Check - Act

10 Alternative to PICO(T) PICOT(T) Population Intervention Comparison or comparisons Outcome Type of study design Time may or may not be included

11 Type of Study Design Evidence-based guidelines Evidence-based algorithm Quality improvement evidence informed Systematic reviews, RCTs etc.

12 CINAHL and PubMed Allow for some of these variations in their search options PubMed clinical queries and special interest CINAHL - EBP

13 Treatment algorithm for the management of type II diabetes

14 Web browser search: ADA guidelines type II diabetes American Diabetes Association Clinical Practice Recommendations 2015 Is google better in finding some types of evidence?

15 What is or should be the expectation of students? Variations in levels of nursing students Train students to be mini librarians? Some literature related to EBP processes

16 Leveling in proficiency of search strategies Undergraduate Basic to advanced How advanced? AD/RN to BSN Traditional BSN Accelerated BSN Graduate MS and DNP Advanced search Learning the EBP process More advanced search methods Novice nurse with AD, diploma vs BSN? Expert nurse with AD, diploma or years from education?

17 More advanced search P = Population I = Intervention C = Comparisons (and, or, not) Boolean operators O = Outcomes T = Time (optional) T = Type of study design Systematic reviews, RCTs Guidelines and algorithms

18 What s in the future? New or different search strategies are needed. Most robust databases to support queries, user-friendly. Librarian consultation. Should all searches be done by librarians or in consultation with one? Can produce more complex search strategies. Can produce more precise searches. Can select best databases to answer the clinical question. Hospital or academic setting librarians available Clinic or primary care office? EBP consultant

19 Ultimate goal: guidelines and algorithms should be embedded into the clinical support system, computerized provide order entry system, the electronic health/medical record and nursing practice in all settings and at every level.

20 Select References Center for Evidence-Based Medicine. Retrieved from Center for Evidence-Based Practice (2014). Quality Management/Library, Medical University of South Carolina. Retrieved from Cook, A., Smith, D., & Booth, A. (2012). Beyond PICO: The SPIDER tool for qualitative evidence synthesis. Qualitative Health Research, 22(10), Duke Center for Nursing Research and Translational Science. Retrieved from Higgins, J.P.T., & Green, S. (Eds.). (2011, March). Cochrane Handbook for Systematic Reviews of Interventions. Retrieved January 17, 2014 from Huang, X., Lin, J., & Demner-Fushman, D. (2006). Evaluation of PICO as a knowledge representation for clinical questions. AMIA Annual Symposium Proceedings,

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