Preparedness for Deliberate Epidemics WHO Approach
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1 Meeting of the States Parties to the BWTC Geneva, 6-10 December 2004 Preparedness for Deliberate Epidemics WHO Approach Dr Ottorino Cosivi Project Leader, Preparedness for Deliberate Epidemics Department of Communicable Disease Surveillance and Response
2 Early WHO efforts on CBW early 1950s: UN approached WHO to investigate allegations of BW use during Korean War. The investigation was not carried out. 1959: WHO contributed to the First Pugwash International Conference of Scientists to assess chemical and biological weapons. 1968: UN requested WHO contribution for the UN report Chemical and Bacteriological (Biological) Weapons and the Effects of their Possible use. 1970: WHO publishes Health aspects of chemical and biological weapons Biological and Chemical Weapons Convention of 1972 and 1993
3 Deliberate use of BC agents: a threat to public health Low probability, high consequence event (mortality, morbidity, panic and fear). New technology biotechnology and genetic engineering contributes to combat CBW; however, it could also be potentially used for non-peaceful purposes. The BWC and CWC include provision for assistance in the event of attack or threat of attack. OPCW As yet there is no similar organization for BW. WHO, among other actors, can provide technical assistance Member States on public health aspects.
4 WHO s Mandate Basic Documents Preamble of the WHO Constitution of 1948 THE STATES Parties to this Constitution declare, in conformity with the Charter of the United Nations, that the following principles are basic to the happiness, harmonious relations and security of all peoples. article 2(d) WHO shall... furnish appropriate technical assistance and, in emergencies, necessary aid upon the request or acceptance of Governments; International Health Regulations Draft revised IHR: public health emergencies of international concern
5 Global public health response to natural occurrence, accidental release or deliberate use of biological and chemical agents or radionuclear material that affect health WHA55.16 (18 may 2002) URGES Member States - to treat any deliberate use as a global public health threat, and to respond to such a threat in other countries by sharing expertise, supplies and resources...; REQUESTS the Director-General - to strengthen global surveillance; - to provide tools and support for Member States, particularly developing countries, in strengthening their national health systems; - to continue to issue international guidance and technical information...; - to examine the possible development of new tools
6 Why deliberately caused epidemics are different? Fundamentally transform the context in which public health services must be delivered in order to ensure human safety and security. Need for national and international roles, responsibilities, and mechanisms to be clearly defined before such incidents occur as a prerequisite for responding with the requisite speed and effectiveness.
7 Deliberate Use of Biological Agents represents a challenge to both Public Health and Security Security Public Health Different roles and responsibilities, different mandates WHO differs fundamentally from the IAEA and the OPCW as it is not in any way empowered to monitor or to verify compliance with international disarmament or non-proliferation agreements
8 Managing risks to public health posed by the deliberate use of biological agents Prevention Preparedness Event Recovery Response
9 Managing risks to public health posed by the deliberate use of biological agents Prevention Preparedness Recovery Response
10 Alert and response operations WHO's Epidemic Intelligence WHO's Epidemiological Verification Public Health Response Follow-up
11 SARS: what we have learned In the world today an infectious disease in one country is a threat to all: infectious diseases do not respect international borders Information and travel guidance can contain the international spread of an infectious disease Experts in laboratory, epidemiology and patient care can work together for the public health good despite heavy pressure to publish academically Emerging infectious disease outbreaks often have an unnecessary negative economic impact on tourism, travel and trade Infectious disease outbreaks reveal weaknesses in public health infrastructure Emerging infections can be contained with high level government commitment and international collaboration if necessary Because it is a naturally-occurring disease, did not test the coordination and interaction between health authorities (such as WHO) and international security mechanisms
12 Managing risks to public health posed by deliberate use of biological agents Preparedness Prevention Recovery Response
13 Disease specific networks (selected BW agents from 2nd edition WHO publication) BACTERIA *Anthrax (Bacillus anthracis) *Brucellosis (Brucella abortus, B. suis and B. melitensis) Glanders (Burkholderia mallei) Melioidosis (Burkholderia pseudommallei) *Tularaemia (Francisella tularensis) *Plague (Yersinia pestis) Q Fever (Coxiella burnetii) Typhus Fever (Rickettsia prowazeki) FUNGI Coccidioidomycosis (Coccidiodes immitis) VIRUSES Venezuelan equine encephalomyelitis *Smallpox (Variola virus)
14 Objectives of activities on Anthrax To establish a global network of anthrax experts and laboratories with defined anthrax capabilities To establish standard procedures relating to anthrax and disseminate information To set up and implement training and quality assurance 1. Contact details Name of laboratory Address City Postal code Country Telephone Fax Web site Communicable Disease Surveillance and Response Global Alert and Response Disease-Specific Networks: Anthrax Questionnaire for Laboratories Global Alert and Response Communicable Disease Surveillance and Response Disease-Specific Networks: Anthrax Questionnaire for Laboratories Name of director of the laboratory Title Telephone Fax Name of person responsible for anthrax activities Title Telephone Fax 2. Your laboratory is affiliated to: Ministry of Health Ministry of Agriculture Other ministries (please specify) Universities Private laboratories Other (please specify) 1. Contact details Name of laboratory Address City Post code Country Telephone Fax Web site Director of the laboratory Title (Prof., Dr, Mr, Mrs, Miss) Telephone Fax Person responsible for anthrax activities Title (Prof., Dr, Mr, Mrs, Miss) Telephone Fax 2. Your laboratory is affiliated to: Ministry of Health Ministry of Agriculture Other ministries (please specify) Universities Private laboratories Other (please specify) Disease-specific networks: improving public health preparedness for and response to the threat of epidemics Mission statement To strengthen global disease-specific networks of experts and laboratories able to provide technical support to response activities in Member States, particularly developing countries, related to the natural occurrence, accidental release, or deliberate use of biological agents that affect health. Global Alert and Response Communicable Disease Surveillance and Response
15 Policy guidance to to Ministries of of Health of of Member States. More More than than experts from from all all WHO WHO regions which act act as as in in their their personal capacities. International Organizations, academia and and NGOs (FAO, ICRC, OIE, OIE, OPCW, WFP, WFP, UN, UN, Harvard-Sussex Program, Pugwash).
16 Elements of guidelines development Guidelines for Assessing National Health Preparedness Programmes for the Deliberate Use of Biological and Chemical Agents Country s assessment process how to organise and carry out an assessment and follow up final tool will help country's self assessment Risk assessment Definition of terms, methodology, process, role of the different partners. Prioritisation by comparison of risk assessment for preparedness planning for the deliberate use of BC agents with those for naturally and accidentally occurring diseases, chemical accidents and major natural and technological disasters. Emergency management Review of the elements of a preparedness programme. This will include the assessment of the following domains: National Policy Risk, Hazard and Vulnerability Preparedness Planning Capacity Building and Training Monitoring and Evaluation
17 Guidelines for Assessing National Health Preparedness Programmes for the Deliberate Use of Biological and Chemical Agents INTENT Group, Motivation, Organisational, Opportunity, Objective Set the Context Identify, Analyse, Evaluate THREAT Type, Character, Magnitude CAPABILITY Acquisition, Development, Testing, Target selection, Deployment PUBLIC HEALTH RISK Likelihood, Consequences, Scenario Specific Treat or Accept Risks RISK MANAGEMENT Ranked Priorities, Security Planning, Emergency Planning Health involved in consultation and support Health as a leading agency with other stakeholders
18 Guidelines for Assessing National Health Preparedness Programmes for the Deliberate Use of Biological and Chemical Agents Current field testing process PHASE I PHASE II PHASE III PHASE IV -6 Months -3 Months -2 Months 0 +1 Month Months Agreement Pre-visit Consolidate Documentation Preliminary Assessment Agree Action Plan Self Assessment and Development Review visit 3 Days 3 weeks 3 Days Introductory Workshop Field Visits Report Writing Debriefing Workshop Agree on Follow-up Process 2-3 Days 14 Days 2 days 1 Day 1 Day PHASE II
19 Assessment Domains POLICY RISK, and VULNERABILITY PREPAREDNES and PLANNING TRAINING and DEVELOPMENT MONITORING and EVALUATION
20 Guidelines for Assessing National Health Preparedness Programmes for the Deliberate Use of Biological and Chemical Agents Field testing programme Thailand, September 2003, with the Organisation for the Prohibition of Chemical Weapons (OPCW), the Asian Disaster Preparedness Centre (ADPC). In addition of MoH, 18 agencies participated. Jordan, March/April 2004, with the technical contribution of various Jordanian ministries (health, defence, interior, industry, etc.), Jordanian Red Crescent Society, AusAID, Health Canada, OPCW, UNICEF, as well as different technical programmes from WHO HQ and EMRO. More than 55 institutions/agencies participated. Canada, November-December 2004 (with contribution of OPCW, IAEA). The Philippines, February 2005 (confirmed) Moldova, 2005 (agreed, date to be confirmed) One African country, 2005 (under discussion)
21 Managing risks to public health posed by the deliberate use of biological agents Prevention Preparedness Recovery Response
22 WHO Biosafety Programme Coordination of global Biosafety networks WHO Biosafety Advisory Group (BAG) UN model regulations Transport of infectious substance Biosafety inspections: Smallpox repositories laboratories Laboratory Biosafety Manual 3 rd Edition (2004)
23 WHO s network on deliberate use CB agents The need for a global partnership More than 100 CBW experts from all WHO regions which have contributed to the 2nd edition of the Public health response to biological and chemical weapons: WHO guidance Informal network of CBW disarmament experts and diplomats CBW Working Group (in-house HQ and Regional Offices); CBW Scientific Advisory Group: Being established; Biosafety Advisory Group (BAG); Disease specific laboratory and expert networks (anthrax, smallpox); Global Network of Poisons Centres; Global Network of chemical incident and emergency experts; Inter-Organization Programme for the Sound Management of Chemicals (IOMC); Others, e.g. FAO, OIE, UN, OPCW, IAEA, ICGEB, UNICRI, etc. Others.
24 An address: has been created to answer questions relating to WHO's activities on chemical and biological weapons.
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