GYNAECOLOGY CANCER RESEARCH FUND ANNUAL REPORT AND ACCOUNTS

Transcription

1 GYNAECOLOGY CANCER RESEARCH FUND ANNUAL REPORT AND ACCOUNTS Company Registration Number: Registered Charity Number (England and Wales): Registered Charity Number (Scotland): SC042612

2 Contents Page Chair s Statement 2 Report of the Trustees: Achievement and Performance 3 Objectives for Financial Review 12 Structure, Governance and Management 13 Legal and Administrative Information 15 Statement of Trustees Responsibilities 16 Independent Auditors Report 17 Consolidated Statement of Financial Activities 19 Charity Statement of Financial Activities 20 Balance Sheet 21 Notes to the Accounts Reasons to Support The Eve Appeal 33

3 Chair s Statement This year has been a significant one in that we have now fully funded one of our flagship research projects PROMISE PROMISE stands for Predicting Risk of Ovarian Malignancy, Improved Screening and Early Detection and whilst this research project is coordinated from the Department of Women s Cancer at UCL it does involve four other centres of research excellence: Harvard, the Universities of Cambridge, Manchester and Southern California. Whilst this project will not report for another two years, early results suggest that new biomarkers for ovarian cancer are being identified and that a number of algorithms are being considered, both these things will help to inform a future ovarian cancer screening programme. This is all very exciting and as the lead funder of PROMISE 2016 The Eve Appeal is quite rightly proud to be working with such an expert and dedicated international team of scientists. It is a truth widely acknowledged that early diagnosis of cancer has a massive impact on outcome, in particular, survival rates at 5 years. With this in mind the next large project that The Eve Appeal is planning to fund at UCL is centred on epigenetics and the way genes are turned on or off by inherited, environmental or lifestyle factors - EpiFem. EpiFem is a project which aims to understand, predict, prevent and detect women s cancers long before there are any physiological changes within the body and could, really, totally change the cancer landscape and The Eve Appeal is working with the leaders in the field. So there is much to play for as we move forward into a new era. Of course, none of this could happen without the generosity of donors large and small who through their loyal support help our talented scientists to unlock the secrets of this dreadful set of diseases. And all of us who are involved with The Eve Appeal would like to thank them most sincerely. Helena Morrissey Chair

4 Achievement and Performance: Research Objective 1 - Fund world-class research into early diagnosis, risk prediction and prevention of the five gynaecological cancers We aimed to: Raise at least 600,000 to fund further research into the five gynaecological cancers. We achieved: 450,491 was allocated to fund research. Although below the target set for the year, funding on research as a percentage of total expenditure increased from 35% in 2013 to 39% in Report on all published research that The Eve Appeal has funded. The Eve Appeal reported the results of three scientific papers authored by Professor Martin Widschwendter and his team. Widespread coverage in key national and regional broadcast and print remind us of the importance of this research. Prepare for the next Quinquennial Review on the research funded at University College London to assess the progress made since the last review and the impact achieved. Preparations are progressing well for the next Quinquennial Review which will be held at University College London on 3rd November 2014 chaired by Sir John Pattison. The Eve Appeal s core research unit is the Department of Women s Cancer at University College London (UCL). UCL was recently highlighted as a top five university in the QS world university rankings. The team at UCL is led by Professor Martin Widschwendter, whose own research work focuses on translational research translating research from the lab-bench into tools which are able to eradicate cancer. The backbone to Professor Widschwendter s vision is to UNDERSTAND the nature of cancer development in order to make a real difference in the following three areas: PREDICT who is most likely to develop women s cancers Identify tools and biomarkers that will enable doctors to DETECT the diseases earlier when they are most easily treated Develop medical and surgical strategies to PREVENT women s cancers In its early stages, EpiFem has already demonstrated its value with the researchers having identified one epigenetic signature present in BRCA mutation carriers These principles form the basis of Professor Widschwendter s EpiFem project, which The Eve Appeal is seeking to fund. The team at UCL is multi-disciplinary and always working on a plethora of work at any given time, in addition to the epigenetics work detailed above, the team are currently: Investigating proteins and their role in the causation of women s cancers (proteomics) Conducting and analysing clinical research trials investigating screening, early diagnosis and risk prediction of women s cancers (Gynaecological Cancer Research Centre) Analysing patient care by examining the psychology of women s cancer, including examining the costs and benefits of treatments on quality of life and the psychological effects of cancer on gastrointestinal and sexual health The greater the funding that The Eve Appeal receives, the more of this vital work that we can facilitate.

5 Achievement and Performance: Research continued PROMISE 2016 The PROMISE team commence year four of five of this ground-breaking programme in September The Eve Appeal is delighted to have now raised the funds needed for this flagship programme. Key work that has already taken place includes the identification of biomarkers, initial development of algorithms and statistical analysis. We will continue to update The Eve Appeal s website to ensure that all key achievements are shared with our supporters. UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) Over 200,000 women across the UK participated in an ovarian cancer screening trial that spanned over 10 years. The results are expected in 2015 and The Eve Appeal and the team at UCL look forward to sharing these with our supporters, many of whom were involved in UKCTOCS trial. The results will show whether or not screening for the CA125 biomarker and/or regular transvaginal scans is an effective tool for ovarian cancer screening. The impact of these results will inform and have the potential to transform the current NHS screening protocol for ovarian cancer. Ugandan Women s Health Initiative (UWHI) Cervical cancer is the biggest women s cancer killer in Uganda, with nearly 2,500 women dying from the disease each year. There is currently no national screening programme for cervical cancer in Uganda. The Eve Appeal is funding UWHI, in their efforts to instigate screening and to save lives.

6 Achievement and Performance: Fundraising Objective 2 - Increase income generation through continuous development and diversification of fundraising including: We aimed to: Develop the major donor programme. Continue to raise money through appropriate applications to trusts, foundations and potential corporate partners. Continue to develop interesting and profitable events and community fundraising activities that supporters wish to take part in. We achieved: During the year systems were developed to enable The Eve Appeal to identify potential major donors who might be supportive of the charity. The number of successful trust and foundation applications increased by over 21% compared to the previous year and corporate donations rose by 35%. A new event, the Trekathon, proved to be very successful and there were a record number of teams at our charity shoot. Our community supporters took part in an even wider range of events ranging from runs to bathing in baked beans. Maximise the engagement of existing supporters through timely and relevant communications and a focus on regular giving. The generosity of our supporters in response to our newsletters and mailings was unprecedented and far exceeded expectations. A new programme of raising income from regular giving was also successfully started. Develop and maximise online fundraising and giving opportunities that appeal to existing and new supporters. Our biannual newsletters and mailings were adapted for online giving. Work started at the end of the year on developing new ways to donate on our website. The Eve Appeal relies completely on voluntary income and as such is very grateful to all of our wonderful supporters for their hard graft and generosity. It is impossible to include everyone in this report, but here are a few key highlights of our fundraising year: Trekathon 120 brave women and men tackled a marathon length trek along the iconic Hadrian s Wall. In total, this intrepid group raised 64,000 in the reporting period far exceeding all expectations and despite some grim weather and a challenging route. Due to the success of this event, future Trekathons will take place, with one already planned for September 2014 from Avebury to Stonehenge. Amanda took part with her husband Paul; I signed up to take part in the Trekathon in memory of my Mum, Maureen, who was just 54 when we lost her to ovarian cancer. Paul and I found the experience extraordinary! It was incredibly hard going, but we were delighted to raise over 1,500! I would recommend the experience to anyone!

7 Achievement and Performance: Fundraising continued Bravissimo The lingerie brand for bigger boobed women selected The Eve Appeal as their chosen charity from Autumn 2012 to Spring From skydiving to bake sales, and sample sales to bra recycling, the partnership was a fantastic success with the team raising a total of 33,454. Christmas PROMISE Supporters from all over the UK took part in our Christmas PROMISE appeal, whereby we asked for messages of hope and funds to complete the PROMISE 2016 appeal. This appeal brought an unprecedented response, raising 62,775. We have now fulfilled our fundraising pledge to the PROMISE team, and this would not have been possible without our supporters. I am forever grateful to the team who saved my life 7 years ago and my hope is that PROMISE will save the lives of many more women with ovarian cancer. Christmas PROMISE supporter, Carol Make Time for Tea Once again our supporters surpassed themselves with their baking skills to help raise funds for The Eve Appeal. 177 tea parties were held up and down the country raising 74,374. The tea party was honestly the best thing I have done since losing my mum. Not only has it raised money for a charity and a cause that I believe in, but it has helped me to come to terms with losing her. Cancer has been a huge part of my life, my mum was sick for nine years, and when she died I felt useless and powerless but The Eve Appeal has given me a way to keep on fighting so thank you for that. supporter, Felicity THANK YOU to everyone who has fundraised for or given to The Eve Appeal. Without your support, The Eve Appeal s funding of vital research into women s cancers simply could not continue

8 Achievement and Performance: Profile Objective 3 - Increase profile of The Eve Appeal We aimed to: Continue to exploit all media opportunities. Develop communications platforms in new media (e.g. Twitter, Facebook). We achieved: Another successful year in the media with 752 Eve Appeal branded articles spanning all five gynaecological cancers. A media partnership with Hello! Magazine resulting in 4 full page advertorials. Social media presence continued to rise with Facebook likes increasing from 3041 to 3923 this year an increase of almost 30% and Twitter followers increasing by 31% to Traffic to our website increased by 150% as a result of increased media profile with website views per month increasing from 6600 in 2012/13 to 16,083 in 2013/14. The Eve Appeal was joined by TRHs Prince Nikolaos and Princess Tatiana of Greece on 27th September 2013 to open trading on the London Stock Exchange Website views per month: 18,000 16,000 14,000 12,000 10,000 8,000 6,000 4,000 2,000 - Jul-13 Aug-13 Sep-13 Oct-13 Nov-13 Dec-13 Jan-14 Feb-14 Mar-14 Apr-14 May-14 Jun-14

9 Achievement and Performance: Awareness Objective 4 - Raise awareness of the five gynaecological cancers We aimed to: Build upon Gynaecological Cancer Awareness Month activity in order to promote awareness of all five gynaecological cancers. We achieved: Significant press and broadcast coverage across all gynaecological cancers with this year s focus on womb cancer. Work collaboratively with other charities working to combat women s cancers to maximise awareness raising opportunities. Successfully collaborated with Target Ovarian Cancer, Ovarian Cancer Action, Ovacome, Weight Concern and Cancer Research UK regarding collaborative reporting of co-funded research. Work collaboratively with other organisations with whom we might be able to leverage our message. Worked with the Health and Social Care Information Centre regarding reporting of cervical screening data and Public Health England on Be Clear on Cancer ovarian cancer pilots. Be the Globe-athon partner for the UK. Globe-athon is a world movement aimed at raising awareness of Extensive promotion via social media and The Eve Appeal website. Gynaecological Cancer Awareness Month (GCAM) - September 2013 This year our GCAM awareness activity focused on womb cancer. 50% of cases in post-menopausal women are due to being overweight, so to help us address this we joined forces with Weight Concern, a charity dedicated to promoting maintenance of healthy weight. Cervical Cancer Prevention Week - January 2014 This campaign focused on PREVENTION. Cervical cancer can be prevented! Our brave case study Jacqui Egan shared her very personal story to encourage all women to stay safe from cervical cancer by attending regular screening. Thank you to The Eve Appeal for all their continuous hard work into raising money for research into gynaecological cancers. For someone like me it s good to know that there is someone on our side fighting our corner for a cure. supporter Jacqui Egan. Ovarian Cancer Awareness Month (OCAM) - March 2014 This year s Make Time for Tea campaign was launched at a tea time photoshoot at the House of Commons with David Lammy MP, Sharon Hodgson MP and Robert Marsh former CEO of The Eve Appeal. For many years I have campaigned on behalf of the 3,500 women who die each year from ovarian cancer. I urge you all to support The Eve Appeal s campaign and hold a tea party in March with your friends or colleagues, have fun and make a difference. Sharon Hodgson MP I lost my dear mother and grandmother to ovarian cancer and so am delighted to help The Eve Appeal to support this important event and ask as many people as possible to host a tea party to raise awareness and funds to fight this devastating disease. David Lammy MP

10 Achievement and Performance: Awareness continued As co-founders of for the fourth year we joined forces with other ovarian cancer charities to provide a web-based central portal of information during Ovarian Cancer Awareness Month (OCAM). The site gained further recognition this year with hits during the first quarter of 2014 (run up to OCAM) reaching 5,200 versus 508 for the same period in 2012/13 an impressive increase of 923%. Cervical Screening Awareness Week - June 2014 In the UK, cervical screening is estimated to save over 4,500 lives each year yet 22% of eligible women still don t attend screening when invited. The Eve Appeal worked with print, online and broadcast media, providing case studies and information to address this issue. This resulted in coverage by 40 newspapers, including a double spread in The Sun, 22 news websites, 5 radio stations and countless other websites and blogs, reaching well over 20 million readers/viewers. BE CLEAR ON CANCER In collaboration with Target Ovarian Cancer, Ovarian Cancer Action and Ovacome, we worked with Public Health England (PHE) to launch the Be Clear on Cancer regional ovarian cancer awareness pilot campaign which took place in North West England during February and March As part of this campaign we worked with PHE s multicultural media agency to raise awareness among ethnic communities and especially the South Asian community in North West England. We secured the support of Professor Usha Menon, Head of the Gynaecological Cancer Research Centre, whose interview was featured in South Asian press, TV and radio. Eve Champions Our network of Eve Champions and Public Speakers who represent The Eve Appeal in their local area has grown by 75% this year and we now have 70 volunteers raising awareness and building relationships in their communities. Our thanks to all our volunteers for their valuable time. As an Eve Champion I can help The Eve Appeal but they have also helped me; not only in supporting my family through the darkest and most difficult time of their lives but also in building my self-confidence and feelings of being able to do something to help others, so that the loss of my mum and aunty has not been in vain. Eve Champion, Helen Kay

11 Achievement and Performance: Awareness continued Information Leaflets We have now produced an information leaflet for women on vulval/vaginal cancers. This latest addition joins information leaflets on womb, ovarian and cervical cancers to complete the set. This year we have distributed 12,576 leaflets. General Womb Ovarian Cervical Vaginal/Vulval Total 3,899 1,209 5,108 1,243 1,117 12,576 Achievement and Performance: Governance Objective 5 - Ensure that governance, finance, HR and IT structures are fit for purpose We aimed to: Ensure that governance, finance, HR and IT structures are fit for purpose. We achieved: Achievements in the year included an updated employee and Trustee handbook, new monthly management account reports and review of potential cyber attack risks.

12 Objectives for Research Continue to fund world-class research into early diagnosis, risk prediction and prevention of the five gynaecological cancers Fund the final year of PROMISE 2016 Focus on seeking new funding for EpiFem Report on and disseminate the results of the UKCTOCS trial in conjunction with UCL and Cancer Research UK Help support the work of the Ugandan Women s Health Initiative Report on the second Quinquennial Review of the research funded at UCL to assess the progress made since the last review and in particular the impact of The Eve Appeal funding. Nurse-Led Information Service Secure funding for the pilot of the Nurse-Led Information Service and successfully recruit a gynaeoncology nurse to roll out the service one day a week for a pilot period of 6 months The pilot project will aim to develop and implement methods of delivering comprehensive information and support in a range of formats, for people affected by gynaecological cancers, their families, friends, and health and social care professionals Evaluate and report on the success of the pilot project and, subject to satisfactory performance and measurable outcomes, seek funding to secure the future of the Nurse-Led Information Service Awareness Work closely with the Department of Women s Cancer at UCL to communicate the latest science news and successes to our target audience Plan and facilitate awareness campaign for Gynaecological Cancer Awareness Month in September 2014 Support and communicate awareness of World Ovarian Cancer Day, 8th May 2015, as widely as possible Collaborate with Target Ovarian Cancer, Ovarian Cancer Action and Ovacome to produce a guide for women under 45 diagnosed with ovarian cancer Collaborate with other cancer charities and organisations to deliver awareness messages to our target audience Fundraising Increase income generation for the charity as a whole Introduce new events to reach new audiences and bring new supporters into the charity Seek new partnerships with companies that could also raise the profile of the charity and awareness of women s cancers Increase regular giving from core supporters Develop our long-term legacy programme Governance, finance, HR and IT Ensure that governance, finance, HR and IT structures continue to be fit for purpose

13 Financial Review Review of Financial Position Income for the year ended 30th June 2014 fell by 255,090 (19%). The Eve Appeal holds a biennial ball and this was last held in 2013 which had an income of 266,597. Removing the effect of this income there was a modest increase in income from 2013 to 2014 of 11,507. There were several areas of income which saw significant growth and these included donations from individuals (an increase of 14%). The response to the Christmas PROMISE 2016 Appeal and other mailings was very strong. Other areas of growth included income from corporates (an increase of 35%) and events income which, excluding the biennial ball, increased by almost five times. The most significant decreases were seen in community income and trusts, although the number of trust donations rose the average amount of the donations fell. A breakdown of income by area can be found on page 25 of the notes and in the chart below. Individuals (36.5%) Community (31.2%) Events (11.0%) Trusts and foundations (10.0%) Corporate (5.9%) Donated services (2.4%) Legacies (1.9%) Trading subsidiary (0.9%) Interest (0.2%) Expenditure before research fell by 156,916. The fall in expenditure was mostly due to not holding the biennial ball and also a reflection of the focus placed on reducing the running costs of the charity in line with income. Expenditure on research grants was 450,491 in 2014 leading to net outgoings for the year of 58,005, compared to 474,200 of research expenditure in 2013 and net incoming resources of 16,460. The percentage of expenditure spent on charitable activities was 61%in 2014 compared to 59% in Reserves Policy The Trustees reviewed the reserves policy of the charity at their Board meeting on 27th June The Trustees considered the nature of the charity s restricted income, budgets, future plans and unexpected calls on the charity s funds and decided to amend the policy to be a minimum of four months budgeted expenditure, excluding expenditure on research grants. It was agreed that the amount should be altered each year in-line with the annual budget. Free reserves as at 30th June 2014 were 635,281, however this was offset by deficit restricted reserves of 343,702 leading to net free reserves of 291,579. The deficit restricted reserves occurred where grant expenditure was committed to PROMISE 2016 before the restricted income was received. Given the clear commitment of major donors to funding PROMISE 2016, the Trustees allowed restricted expenditure in advance or receiving the donations. 100,000 of these committed donations was received in September The net free reserves were the equivalent of just over four and half months budgeted running costs for the charity. Going Concern The Trustees have reviewed the charity s financial position, taking into account the levels of reserves, cash, committed income that has not been included in the accounts, future plans and its systems of financial and risk management. The Trustees believe that the charity is well placed to manage operational and financial risks successfully. Accordingly, the Trustees have a reasonable expectation that the charity have adequate resources to continue in operation for the foreseeable future and therefore adopt the going concern basis of accounting in preparing the annual accounts.

14 Structure, Governance and Management Gynaecology Cancer Research Fund is a company limited by guarantee and is a registered charity which is governed by its Memorandum and Articles of Association. The charity is also know as The Eve Appeal. The company was incorporated on 8th February 2002 and gained charitable status on 23rd April Principal Activity The charity was established exclusively to advance research into gynaecological cancers, and to relieve the suffering of women with gynaecological cancer by providing, educating and training the public in the methods of diagnosis and care of women suffering from a gynaecological cancer. Board of Trustees The charity is governed by a Board of Trustees who are both members and directors of the charity. As at 30th June 2014 there were 11 Trustees chaired by Helena Morrissey. The company may by ordinary resolution appoint a person who is willing to act as a trustee either to fill a vacancy or as an additional Trustee. Under clause 24 of the Articles of Association, the minimum number of Trustees shall be three, with no maximum number, unless otherwise determined by ordinary resolution at a general meeting. No Trustee can serve for more than three years and must retire by rotation. On retirement, a Trustee shall be, if willing to act, eligible for reappointment to the Board of Trustees. The office of a Trustee shall be vacated if he or she resigns by notice to the company or if he or she is disqualified under clause 42 of the Articles of Association. Under clause 27 of the Articles of Association, the Board of Trustees may delegate any of their powers to any specifically formed committee. Such committees can be composed of any mix of Trustees and non Trustees as deemed appropriate by the passing of a resolution. Any such committees report regularly direct to the Board of Trustees. Delegated powers are revocable by the Trustees at any time. The charity ensures that it complies with minimum requirements in its selection, induction and training of Trustees. Specifically, the overall policy is to: Have a clear written role description and person specification for Trustees Have an induction process for Trustees, including an induction pack Provide training as part of this where a need is identified on an individual basis Undertake a review of Trustee training on an annual basis and provide appropriate training if requested as part of this Ensure that the CEO flags with the Trustees any training opportunities that arise during the year in addition to this annual review Public Benefit We have referred to the guidance contained in the Charity Commission s general guidance on public benefit when reviewing our aims and objectives and in planning our future activities. The Eve Appeal has two principal activities which directly demonstrate public benefit. These are the funding of world-class research into the five gynaecological cancers and the raising of awareness of these cancers in the United Kingdom. The research funded has a potential to benefit all those affected by gynaecological cancers globally through improved risk prediction, early diagnosis and improved treatment. Through awareness raising The Eve Appeal increases knowledge in the wider general public of gynaecological cancers, and in particular, their signs and symptoms. Women who are able to recognise the signs and symptoms of these cancers early stand a better chance of being diagnosed more quickly and we know that early diagnosis saves lives.

15 Structure, Governance and Management: continued Risk Management The Trustees have assessed and reviewed the major strategic, business and operational risks which the charity faces and confirm that systems are established to mitigate the charity s exposure to those risks. Grant Making Policy The policy of the Trustees is to fund world-class research into the five gynaecological cancers. The Pattison Review (undertaken June 2009) stated that the Gynaecology Cancer Research Centre (GCRC) at UCL leads the field in the UK and that elements of the work are truly of the highest international standard. Trustees took the view in January 2010 the Trustees confirmed that the research being undertaken at the GCRC is within its remit and will therefore continue to prioritise its grant giving to UCL. The Trustees have commissioned a new review to take place in November In June 2012 the Trustees agreed to fund the Uganda Women s Health Initiative s (UWHI) cervical cancer project. Funding for UWHI is directed via UCL. The Trustees meet as necessary, and at least quarterly, to review the cash available and approve requests made by UCL and the PROMISE 2016 programme to fund their research. UCL and the PROMISE 2016 programme provide, in advance of these meetings, prioritised applications for research funding including details of the project to be funded. The charity s policy is to make funds available to support the research programmes. Investment Policy The policy of the charity is to adopt a low risk strategy at present and therefore it maintains excess funds in a deposit account, which allows ready access to funds. In addition the current policy is to realise any equity investments received by way of gift or legacy as soon as the charity is able. Auditor A resolution to reappoint Chantrey Vellacott DFK LLP as auditor for the ensuing year will be proposed at the Annual General Meeting in accordance with section 485 of the Companies Act Small Company Provisions This report has been prepared in accordance with the special provisions for small companies under Part 15 of the Companies Act Authorised by the Trustees on 26th September 2014 and signed on their behalf by: Helena Morrissey CBE Chair

16 Legal and Administrative Information Charity Name Gynaecology Cancer Research Fund trading as The Eve Appeal Royal Patron Trustees HM Queen Anne-Marie Sally Bailey (appointed 27th June 2014) Alexander Fitzgibbons Emma Gervasio (appointed 28th March 2014) Professor Ian Jacobs Angus MacLennan (Vice Chairman) Helena Morrissey CBE (Chair) David Oram Melanie Richards Anthony Silverstone Per Troen Peter Vagn-Jensen (resigned 28th March 2014) Anne Watts CBE Chief Executive Robert Marsh (resigned 30th May 2014) Company Secretary Cosec Direct Limited Registered Charity Number (England and Wales): Registered Charity Number (Scotland): SC Registered Company Number: Principal office of charity and registered office 15B Berghem Mews, Blythe Road, London, W14 0HN Auditor Chantrey Vellacott DFK LLP, Russell Square House, Russell Square, London, WC1B 5LF Bankers CAF Bank Limited, 25 Kings Hill Avenue, Kings Hill, West Malling, Kent, ME19 4JQ Solicitors Bates Wells Braithwaite, Scandinavian House, 2-6 Cannon Street, London, EC4M 6YH

17 Statement of Trustees Responsibilities The Trustees (who are also directors of Gynaecology Cancer Research Fund for the purposes of company law) are responsible for preparing the Trustees Report and the financial statements in accordance with applicable law and United Kingdom Accounting Standards (United Kingdom Generally Accepted Accounting Practice). Company and charity law requires the Trustees to prepare financial statements for each financial year. Under company law the Trustees must not approve the financial statements unless they are satisfied that they give a true and fair view of the state of affairs of the charitable company and the group and of the incoming resources and application of resources, including the income and expenditure, of the charitable group for that period. In preparing these financial statements, the Trustees are required to: Select suitable accounting policies and apply them consistently Observe the methods and principles in the Charities SORP Make judgements and estimates that are reasonable and prudent State whether applicable UK Accounting Standards have been followed, subject to any material departures disclosed and explained in the financial statements Prepare the financial statements on the going concern basis unless it is inappropriate to presume that the charitable company will continue in business The Trustees are responsible for keeping adequate and proper accounting records that are sufficient to show and explain the charitable company s transactions and disclose with reasonable accuracy at any time the financial position of the charitable company and enable them to ensure that the financial statements comply with the Companies Act 2006 and the Charities and Trustee Investment (Scotland) Act 2005 and the Charities Accounts (Scotland) Regulations 2006 (as amended). They are also responsible for safeguarding the assets of the charitable company and the group and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities. In so far as the Trustees are aware: There is no relevant audit information of which the charitable company s auditor is unaware The Trustees have taken all steps that they ought to have taken to make themselves aware of any relevant audit information and to establish that the auditor is aware of that information The Trustees are responsible for the maintenance and integrity of the corporate and financial information included on the charitable company s website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements may differ from legislation in other jurisdictions.

18 Independent Auditor s Report to the Members and Trustees of the Gynaecology Cancer Research Fund We have audited the financial statements of the Gynaecology Cancer Research Fund for the year ended 30th June 2014 which comprise the consolidated Statement of Financial Activities, the parent statement of Financial Activities, the consolidated and parent Balance Sheets and the related notes. The financial reporting framework that has been applied in their preparation is applicable law and United Kingdom Accounting Standards (United Kingdom Generally Accepted Accounting Practice). This report is made solely to the company s members, as a body, in accordance with Chapter 3 of Part 16 of the Companies Act 2006 and to the company's Trustees, as a body, in accordance with regulations made under section 44 of the Charities and Trustee Investment (Scotland) Act Our audit work has been undertaken so that we might state to the Company s members those matters we are required to state to them in an auditors report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the Company and the Company s members as a body, for our audit work, for this report, or for the opinions we have formed. Respective responsibilities of Trustees and auditor As explained more fully in the Trustees' Responsibilities Statement, the Trustees are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view. We have been appointed as auditor under section 44(1)(c) of the Charities and Trustee Investment (Scotland) Act 2005 and under the Companies Act 2006 and report in accordance with those Acts. Our responsibility is to audit and express an opinion on the financial statements in accordance with applicable law and International Standards on Auditing (UK and Ireland). Those standards require us to comply with the Auditing Practices Board's Ethical Standards for Auditors. Scope of the audit of the financial statements An audit involves obtaining evidence about the amounts and disclosures in the financial statements sufficient to give reasonable assurance that the financial statements are free from material misstatement, whether caused by fraud or error. This includes an assessment of: whether the accounting policies are appropriate to the company's circumstances and have been consistently applied and adequately disclosed; the reasonableness of significant accounting estimates made by the directors; and the overall presentation of the financial statements. In addition, we read all the financial and non-financial information in the Annual Report to identify material inconsistencies with the audited financial statements and to identify any information that is apparently materially incorrect based on, or materially inconsistent with, the knowledge acquired by us in the course of performing the audit. If we become aware of any apparent material misstatements or inconsistencies we consider the implications for our report. Opinion on financial statements In our opinion the financial statements: Give a true and fair view of the state of the group s and the parent company s affairs as at 30th June 2014 and of the group s incoming resources and application of resources, including its income and expenditure, for the year then ended Have been properly prepared in accordance with United Kingdom Generally Accepted Accounting Practice Have been prepared in accordance with the Charities and Trustee Investment (Scotland) Act 2005 and regulations 8 of the Charities Accounts (Scotland) Regulations 2006 (as amended) and with the requirements of the Companies Act 2006

19 Independent Auditor s Report to the Members and Trustees of the Gynaecology Cancer Research Fund: continued Opinion on other matter prescribed by the Companies Act 2006 In our opinion the information given in the Annual Report for the financial year for which the financial statements are prepared is consistent with the financial statements. Matters on which we are required to report by exception We have nothing to report in respect of the following matters where regulations made under the Charities and Trustee Investment (Scotland) Act 2005 and where the Companies Act 2006 requires us to report to you if, in our opinion: Adequate and proper accounting records have not been kept, or returns adequate for our audit have not been received from branches not visited by us; or The financial statements are not in agreement with the accounting records and returns; or Certain disclosures of Trustees' remuneration specified by law are not made; or We have not received all the information and explanations we require for our audit; or The trustees were not entitled to prepare the financial statements in accordance with the small companies regime and take advantage of the small companies exemption in preparing the Trustees Annual Report (incorporating a Directors Report) and take advantage of the small companies exemption from the requirement to prepare a strategic report. STEPHEN CORRALL (Senior Statutory Auditor) for and on behalf of CHANTREY VELLACOTT DFK LLP Chartered Accountants and Statutory Auditor London, UK Date: CHANTREY VELLACOTT DFK LLP is eligible to act as an auditor in terms of section 1212 of the Companies Act 2006

20 Consolidated Statement of Financial Activities (incorporating an income and expenditure account) for the year ended 30th June 2014 Notes Unrestricted Funds Restricted Funds Total 2014 Total 2013 Incoming resources Incoming resources from generated funds Voluntary income 663, , , ,588 Activities for generating income 197,910 1, , ,271 Investment income 2,057-2,057 3,435 Total incoming resources 4 863, ,786 1,100,204 1,355,294 Resources expended Costs of generating funds Costs of generating voluntary income 7 298, , ,417 Cost of activities for generating funds 7 121, , ,472 Charitable activities 7 262, , , ,413 Governance costs 7 29,853-29,853 20,532 Total resources expended 711, ,296 1,158,209 1,338,834 Net incoming/(outgoing) resources, before transfers 151,505 (209,510) (58,005) 16,460 Transfers 16, Total funds at 1st July ,776 (134,192) 349, ,124 Total funds at 30th June ,17 635,281 (343,702) 291, ,584 All the above amounts relate to continuing activities. The notes on pages 22 to 32 form part of these accounts. There are no recognised gains or losses other than the income and expenditure for the year.

21 Charity Statement of Financial Activities (incorporating an income and expenditure account) for the year ended 30th June 2014 Incoming resources Incoming resources from generated funds Notes Unrestricted Funds Restricted Funds Total 2014 Voluntary income 663, , , ,588 Activities for generating income 187,647 1, , ,576 Investment income 8,430-8,430 16,990 Total incoming resources 4 859, ,786 1,096,314 1,351,154 Total 2013 Resources expended Costs of generating funds Costs of generating voluntary income 7 298, , ,417 Cost of activities for generating funds 7 117, , ,332 Charitable activities 7 262, , , ,413 Governance costs 7 29,853-29,853 20,532 Total resources expended 708, ,296 1,154,319 1,334,694 Net incoming/(outgoing) resources, before transfers 151,505 (209,510) (58,005) 16,460 Transfers 16, Total funds at 1st July ,776 (134,192) 349, ,124 Total funds at 30th June ,17 635,281 (343,702) 291, ,584 All the above amounts relate to continuing activities. The notes on pages 22 to 32 form part of these accounts. There are no recognised gains or losses other than the income and expenditure for the year.

22 Balance Sheet as at 30th June 2014 Fixed assets Notes 2014 Group Charity Tangible assets 12 26,616 40,706 26,616 40,706 Investments ,617 40,707 26,618 40,708 Current assets Debtors 14 93, , , ,517 Cash in bank and in hand 655, , , , , , , ,649 Creditors: amounts falling due within one year 15 (484,614) (512,551) (481,899) (507,771) Net current assets 264, , , ,878 Total assets 291, , , ,586 Funds Unrestricted , , , ,776 Restricted 17 (343,702) (134,192) (343,702) (134,190) Total funds 291, , , ,586 These accounts are prepared in accordance with the special provisions of Part 15 of the Companies Act 2006 relating to small entities. These financial statements were approved by the Trustees and authorised for issue on 26th September 2014 and were signed on its behalf by: Helena Morrissey CBE Chair Company registration number: The notes on pages 22 to 32 form part of these financial statements.

23 Notes to the Accounts 1. ACCOUNTING POLICIES (a) Accounting Convention The financial statements are prepared on the historical cost basis and in accordance with applicable accounting standards, The Companies Act 2006, the Charities Act 2011, the Charities Accounts (Scotland) Regulations 2006 and the Charities and Trustee Investment (Scotland) Act 2005, the Statement of Recommended Practice, SORP 2005 Accounting and Reporting by Charities, issued in 2005 (SORP 2005), and updated in July (b) Group Financial Statements These financial statements consolidate the results of the charity and its wholly owned subsidiary, Eve Appeal Limited, on a line by line basis. (c) Funds Unrestricted funds comprise accumulated surpluses and deficits on general funds. They are available for use at the discretion of the Trustees in furtherance of the general charitable objectives. Restricted funds are funds subject to specific restrictions imposed by the donors. (d) Incoming Resources Incoming resources represent amounts receivable by the charity during the year from all sources. All incoming resources are included in the Statement of Financial Activities when the charity is legally entitled to the income and the amount can be quantified with reasonable accuracy. Legacies are accounted for when the charity has entitlement, is reasonably certain of receipt and the amount is measurable. Donations are accounted for on a receivable basis. Activities for generating funds are accounted for on a receivable basis and in the year to which they relate. Donated services and facilities are included in the Statement of Financial Activities at a valuation which is an estimate of the financial cost borne by the donor where such a cost is qualified and measurable. No amounts are recognised when there is no financial cost borne by a third party. Interest is included on a receivable basis. (e) Resources Expended Resources expended are accounted for on an accruals basis and are inclusive of irrecoverable VAT. Grants payable are charged to the Statement of Financial Activities when authorised by the Board of Trustees and communicated to the recipient. Charitable expenditure comprises those costs incurred by the charity in the delivery of its objectives. It included both costs that can be allocated directly to such activities and the costs of an indirect nature as necessary to support them. Cost of generating funds comprise fundraising costs and the costs incurred in the subsidiary trading activities. Fundraising costs include advertising, producing publications, printing and mailing fundraising materials, associated staff costs and an appropriate allocation of support costs.

24 Notes to the Accounts: continued Support costs are those costs incurred in support of the charity s primary objectives and allocated on the basis of staff time spent on those objectives. Governance costs are those costs relating to compliance with constitutional and statutory requirements and the structure and governance review. (f) Fixed Assets and Depreciation Fixed assets are recorded at cost. Depreciation is provided on all tangible fixed assets in order to write off their cost by equal annual instalments over their expected useful lives. The rate adopted is as follows:- Fixtures and Fittings 25% on cost (g) Tax Status Gynaecology Cancer Research Fund (Limited by Guarantee) is a registered company, number and is exempt from corporation tax under the provisions of Sections of the Corporation Taxes Act (h) Operating Leases Rentals payable under operating leases are charged to the Statement of Financial Activities as incurred over the period of the lease. (i) Pension The charity operates a defined contribution pension scheme. The contributions to the defined contribution scheme are charged to the Statement of Financial Activities as they become payable. (j) Cash Flow Statement The charity has taken advantage of the exemptions available and not produced a cash flow statement on the grounds of its size. 2. NET MOVEMENT IN FUNDS Total Funds 2014 Total Funds 2013 Net movement in funds is stated after charging: Auditor s Remuneration - current year 7,320 7,240 Depreciation 16,258 16,855 Operating leases: - Land and buildings 13,146 14,302 - Other 8,882 10,415

25 Notes to the Accounts: continued 3. RESEARCH GRANTS AWARDED Included in Charitable Activities were the following research grants: Grants were awarded to the University College London (UCL) and the University of Manchester for the PROMISE 2016 programme University College London - Core Unit Translational research and epigenetics - 55,000 Predictive test development - 112,800 Small cell gynaecological cancers 5,820 16,400 Total grants awarded to UCL - Core Unit 5, ,200 PROMISE 2016 The University of Manchester core management and research assistant 44,223 67,028 University College London: Core management 27,000 3,000 Risk stratification Early detection and discovery 200, ,755 Total University College London 227, ,239 University of Cambridge - risk stratification 44,132 - University of Harvard - early detection and discovery 52,000 31,000 University of Southern California - risk stratification 48,143 15,733 Total grants awarded to PROMISE , ,000 Uganda Women s Health Initiative 28,710 - Total grants awarded 450, ,200

26 Notes to the Accounts: continued 4. INCOMING RESOURCES Community 332, ,928 Major donors 155, ,314 Direct marketing 151,136 93,310 Special events 121, ,903 Trusts and foundations 110, ,636 General individual giving including 500 Club and regular giving 67,078 95,201 Corporate 64,486 47,799 In memory/in celebration 28,055 42,800 Donated services 26,514 82,374 Legacies 21,000 8,527 Regional 10,765 11,372 Gift Aid from trading subsidiary 6,373 13,555 Interest 2,057 3,435 Charity income 1,096,314 1,351,154 Less: Gift Aid from trading subsidiary (6,373) (13,555) Trading subsidiary 10,263 17,695 Consolidated income 1,100,204 1,355, STAFF COSTS Wages and salaries 326, ,797 Social security costs 30,765 31,431 Staff pensions 13,335 10,479 Charity income 370, ,707 Cost of contracts 36,099 36,635 Total staff costs 407, ,342 Pension contributions totalling 2,019 (2013: 1,004) were payable to the fund at the balance sheet date and are included in creditors. The number of employees of the Charity paid with in the following range was: 90,000 to 100, ,001 to 110, Pension contributions of 4,125 (2013: 4,500) were payable to higher paid staff.

27 Notes to the Accounts: continued 5. STAFF COSTS: continued The average number of employees, calculated on a full time equivalent basis, analysed by function was: Charitable activities 1 1 Fundraising and support 7 6 The number of employees who accrued benefits under company pension schemes was as follows: 6. TRUSTEES REMUNERATION AND REIMBURSED EXPENSES None of the Trustees received any remuneration during the year. During the year 367 (2013: 831) was paid in respect of Trustees Indemnity Insurance. No Trustees claimed for any expenses during the year (2012: none). 7. ANALYSIS OF EXPENDITURE Direct Costs Support Costs Total 2014 Costs of generating voluntary income 239,721 58, , ,417 Cost of activities for generating funds 94,823 23, , ,332 Charitable activities 630,967 77, , ,413 Governance costs 25,777 4,076 29,853 20,532 Charity 991, ,031 1,154,319 1,334,694 Total 2013 Trading company expenditure 3,890-3,890 4,140 Consolidated 995, ,031 1,158,209 1,338,834

28 Notes to the Accounts: continued 8. ANALYSIS OF SUPPORT COSTS Staff costs 71,975 36,962 Temporary staff, contractors and professional fees 9,576 19,300 Recruitment ,576 Information Technology 9,681 12,401 Depreciation and dilapidations 14,633 15,230 Office running costs 49,096 50,458 Other overheads 4,184 3,255 Bank charges 2,985 2, , , DIRECT COSTS OF GENERATING VOLUNTARY INCOME Community 81, ,250 General individual giving including 500 Club and regular giving 63,273 76,687 Central 26,377 49,390 Corporate 24,699 18,943 Trusts and foundations 23,452 14,458 Major donors 19,904 15,005 Legacies 775 2, , , DIRECT CHARITABLE ACTIVITIES Research grants 450, ,200 Staff costs 102, ,940 Information, awareness and profile 78, , , , DIRECT GOVERNANCE COSTS Staff costs 13,890 11,962 Directors insurance Audit fee 7,320 7,200 Other costs 4, ,777 20,532

29 Notes to the Accounts: continued 12. TANGIBLE FIXED ASSETS - Charity and group As at 30th June 2014 Total cost At 1st July ,006 Additions 2,168 Disposals - At 30th June ,174 Depreciation At 1st July ,300 Disposals - Charge for the year 16,258 At 30th June ,558 Net book value at 30th June ,616 Net book value at 30th June , INVESTMENTS Shares in Subsidiary Undertakings Cost at 1st July 2013 and 30th June Holdings of more than 20% The company holds more than 20% of the share capital of the following companies: Company Country of registration or incorporation Class % shares held Nature of Activity Eve Appeal (UK) Limited England and Wales Ordinary 100 Dormant 1 Eve Appeal Limited England and Wales Ordinary 100 Trading 1 2

30 Notes to the Accounts: continued 13. INVESTMENTS HELD AS FIXED ASSETS Charity continued Net income from trading activities of subsidiary The Charity has a wholly owned subsidiary incorporated in England, Eve Appeal Limited, which raises funds through trading activity including cause related marketing and sales of goods. The company pays its profits under Gift Aid to the Gynaecological Cancer Research Fund. Audited accounts will be filed with the Registrar of Companies. A summary of its trading results (included within Costs of generating funds ) for the year ended 30th June 2014 is as follows: Turnover 10,263 17,695 Administration expenses (3,890) (4,140) Net profit 6,373 13,555 Income transferred by Gift Aid (6,373) (13,555) Retained profit - - Reserves Called up share capital 1 1 Profit and loss account - - Members funds/net assets DEBTORS 2014 Group Charity Trade debtors 1,903 2, Other debtors 1, , Prepayments and accrued income 90, ,777 90, ,777 Amounts owed from subsidiary undertaking - - 8,110 11, , , , ,517

31 Notes to the Accounts: continued 15. CREDITORS: amounts falling due within one year 2014 Group Charity Trade creditors 23,894 15,815 23,895 15,815 Other creditors 3,396 1,544 3,396 1,544 Accruals 7,174 9,250 5,124 7,200 Social security and other taxes 6,885 11,742 6,219 9,012 Grants 443, , , , , , , , UNRESTRICTED FUNDS At 1st July 2013 Incoming resources Outgoing resources Transfers At 30th June 2014 General funds 203, ,418 (711,913) 34, ,176 Designated funds: Emergency fund 280, (34,895) 245,105 Emergency fund 483, ,418 (711,913) - 635,281 The reserves policy for the charity, as agreed by the Trustees, is to maintain a minimum of four months budgeted expenditure, excluding expenditure on research grants.

32 Notes to the Accounts: continued 17. RESTRICTED FUNDS At 1st July 2013 Incoming resources Outgoing resources At 30th June 2014 PROMISE 2016 (138,061) 203,870 (411,016) (345,207) Uganda Women s Health Initiative 2,710 26,300 (28,710) 300 Small Cell Gynaecological Cancers 994 4,841 (5,820) 15 Predictive Test Development (EpiFem) 165 1,025-1,190 Awareness (750) - (134,192) 236,786 (446,296) (343,702) Grants All grants are given to one of the three following programmes: Core Research at the Department of Women s Cancer at University College London. This includes the work on Small Cell Gynaecological Cancer, Predictive Test Development and Translational Research and Epigenetics PROMISE 2016 being undertaken at University College London, the universities of Manchester, Harvard and Cambridge and the University of Southern California The Uganda Women s Health Initiative The PROMISE 2016 negative reserve represents grant expenditure committed in the financial year which will be funded from future restricted income already committed but not yet received and so not accounted for in 2013/2014. More information on the research and grants can be found in the research review on pages 3 and ANALYSIS OF NET ASSETS BETWEEN FUNDS Unrestricted funds Restricted funds Total Fixed assets 26,616-26,616 Current assets 1,093,279 (343,702) 749,577 Creditors: amounts falling due within one year (484,614) - (484,614) 635,281 (343,702) 291,579

33 Notes to the Accounts: continued 19. COMPANY STATUS The charity is limited by guarantee and therefore does not have a share capital. The liability of the members is limited to the sum of 1 per member, and the number of members was 11 (2013: 10). 20. RELATED PARTY TRANSACTONS During the year under review, the charity received incoming resources totalling 154,750 in donations from 8 of its Trustees and 2 Trustee spouses or associated organisations (2013: 210,205 from 9 Trustees and 2 Trustee spouses). The charity received company secretariat services from Cosec Direct Ltd, a company of which Per Troen was a director during the previous financial year (up to February 2013). An amount of 600 (2013: 600) was included in donated services for these services. A total of nil was paid for these services (2013: nil). In the previous financial year the charity received legal services from Corren Troen, a law firm for which Per Troen was Senior Partner. A total of 1,320 was paid for these services in COMMITMENTS UNDER OPERATING LEASES At the date of signing the financial statements, the charity had aggregate annual commitments under noncancellable operating leases as set out below: Land and buildings Other items Land and buildings Other items Operating leases which expire: Within one year - 2, Within two to five years 19,410 5,216 13,146 8,780 19,410 7,889 13,146 8,780

34 10 Reasons to Support The Eve Appeal 1. Every day in the UK 55 women are diagnosed with a gynaecological cancer and 21 will die. Over 1 million women worldwide will be diagnosed with a gynaecological cancer this year and almost half a million will die, The Eve Appeal is determined to change this 2. We are the only national gynaecological cancer research charity in the UK 3. Awareness of gynaecological cancers is very low and many women do not even know there are five gynaecological cancers 4. In recent years there has been a rise in the number of younger women being diagnosed with gynaecological cancers 5. 40% of women with a gynaecological cancer will not survive; despite these grim statistics, gynaecological cancer is not a well-funded cause 6. The Eve Appeal shares in a united vision with the Department of Women's Cancer at University College London to significantly reduce the current 40% mortality rate from gynaecological cancers 7. We fund world-class research at University College London, University of Cambridge, University of Manchester, University of Southern California and Harvard Medical School 8. Our core research unit at the University College London has already achieved major breakthroughs towards improving survival rates of women with gynaecological cancers through pioneering research into screening, early diagnosis and risk prediction 9. People are often too embarrassed to discuss gynaecological cancers or the signs and symptoms, helping us to raise awareness will change this and help save women's lives 10. Although we are a small charity our contribution is disproportionately large as we fund innovative new research and cover gaps in funding which allows cutting edge research to be launched Address The Eve Appeal 15B Berghem Mews Blythe Road London W14 0HN Telephone office@eveappeal.org.uk Twitter twitter.com/theeveappeal Facebook The Eve Appeal