GMS 640: Introduction to Biomedical Information Grants Handout. Grants. Grant facts (NIH)

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1 GMS 640: Intrductin t Bimedical Infrmatin Grants Handut Grants Grant facts (NIH) The NIH, cmprising 27 institutes and centers, prvides a significant amunt f funding fr US medical research. It awards nearly 50,000 cmpetitive grants t an estimated 325,000 researchers at mre than 3,000 universities, medical schls, and ther research institutins. Except industry spnsrs (pharmaceutical, bitechnlgy, and medical device firms), NIH is the largest financier f bimedical research. In 2003, funded 28% f all bimedical research. In 2007, NIH awarded ver 21 billin dllars in grant funding, but the amunt has decreased by 16% ver the past 5 years, when adjusted fr inflatin Massachusetts cnsistently ranks 2 nd, natinwide (behind Califrnia), in the amunt f funding awarded by NIH. In 2007, ver $2 billin was awarded t MA researchers and institutins. NIH awarded Bstn University ver $194 millin dllars in Tufts was awarded ver $97 millin, and MIT ver $196 millin. Open Access Intrductin t Open Access Open-access (OA) literature is digital, nline, available t all users free f charge, and mstly withut cpyright and licensing restrictins. Lked t as an alternative t cnventinal academic jurnals (the cst f which has risen 4x faster than inflatin since 1986), plus as a better way t deal with the infrmatin explsin caused by the internet. Tw types f literature that wrk well with pen access: 1. "Ryalty free literature" - authr gives the wrk nt expecting payment - wrks well with science and academic literature because mstly dne fr impact f research, nt financial reward - schlarly jurnals d nt pay authrs fr their articles.

2 2. Tax-payer supprted research. Leads t NIH public access plicy: The NIH Public Access Plicy ensures that the public has access t the published results f NIH funded research. It requires scientists t submit jurnal articles that arise frm NIH funds t the digital archive PubMed Central ( The Plicy requires that these articles be accessible t the public n PubMed Central t help advance science and imprve human health. PubMed Central PubMed Central is a free digital archive f bimedical and life sciences jurnal literature at the U.S. Natinal Institutes f Health (NIH), develped and managed by NIH's Natinal Center fr Bitechnlgy Infrmatin (NCBI) in the Natinal Library f Medicine (NLM). With PubMed Central, NLM is taking the lead in preserving and maintaining unrestricted access t the electrnic literature. PubMed Central aims t fill the rle f a wrld class library in the digital age. NLM believes that giving all users free and unrestricted access t the material in PubMed Central is the best way t ensure the durability and utility f the archive as technlgy changes ver time. Using PubMed Central Dem: Genetics Using the alphabet links select g and navigate t Genetics. This jurnal is available back t its first issue frm 1916 Similar t the majrity f PMC jurnals there is a 3 mnth embarg n the cverage. The verwhelming majrity f jurnals prvide access t their material within a year f publicatin. Click n the title link t demnstrate hw t navigate thrugh the jurnal Click n search: This ptin retrieves all f the articles available fr this jurnal.

3 Advanced Search: As mst searchers are nt simply lking t brwse a jurnal, but mre specifically fr a particular article students, dems the search feature at the tp f the page, which uses the same basic search interface as PubMed and perfrms a search similar t PubMed. Search fr breast cancer Retrieves: 23 citatins in PMC in Genetics Breast cancer is mapped t the MeSH term breast neplasm Ntice that the limits tab is selected. The limits available in PMC are different than PubMed Exprting int EndNte wuld be handled the same way as if using PubMed PubMed: Users can easily mve between PMC and PubMed using the pull dwn menu at the tp f the PMC page. Run a search fr medical librarian Pay attentin t PubMed icns (see belw) Limit t the PMC subset free articles is a setting fr the My NCBI tl bar Next case: After a great deal f searching, yu and yur clleague believe that there may be a link between yur asthmatic patients and their smking parents. Yu bth decide that yu wuld like t partner n a ptential grant t undertake further research. Yu are unsure where t start, but remember hearing that a clleague had received funding frm the US gvernment and decide t pursue federal funding. Searching fr Funding G t Grants and Funding Subject A-Z frm the library hme page: MedlinePlus Grants.gv Cmmunity f Science Funding Opprtunities (COS)

4 1) NIH Agencies Thrugh MedlinePlus Fr mst disrders and medical tpics, MedlinePlus lists the primary NIH rganizatin cnducting research in that area. Each NIH rganizatin will have a list f grants it is ffering. G t MedlinePlus and pull up the asthma subject page Scrll t the Natinal Institutes f Health n the right side f the page, and click n the crrespnding agency Natinal Heart, Lung, and Bld Institute On the left side click n Funding Opprtunites, then NHLBI grants and cntracts Brse the list f Prgram Annuncements n search capability. Yu can search by keywrd n grants.gv, where infrmatin n these grants is als available, alng with ther funding surces that may apply t yur tpic. 2) Grants.gv A central strehuse fr infrmatin n ver 1,000 grant prgrams. Prvides access t apprximately $400 billin in annual awards. Searches grants frm all f the grant-making federal agencies, including the Department f Health and Human Services, where the NIH is lcated. Click n "Find Grant Opprtunities," then basic search. A keywrd search is better than brwsing by categry r by agency, because these categries yield t many results ("health" r "Dept f Health and Human Services" can't be brken dwn int smaller sectins.) Search fr "tbacc AND asthma Find a grant and learn abut eligibility requirements The grants dn't necessarily have t be tailred t yur specific tpic, s the searches can be pretty brad G int advanced search and refine yur search by eligibility r type f agency (including NIH) 3) Cmmunity f Science (COS) Listed n 'Grants and Funding' subjects A-Z page. "The largest inventry f currently available grant infrmatin," riginally run by Jhns Hpkins, nw wned by CSA, a fr-prfit database vendr. Searches mre than 24,000 recrds fr federal grants as funding pprtunities frm private fundatins, public agencies, crpratins, and natinal and lcal gvernments. Internatinal in scpe and represents ver $33 billin in funding frm a brad range f disciplines. Free t search. Search Search smking AND child* In view results, ntice clustering and rll-vers with descriptin and eligibility Yu can save results (with yur wn tags) and alerts

5 G int Refine Yur Query (r Advanced search depending n whether yu are n a results page r the main search page) and learn the different ways yu can fcus yur search. Other resurces: CRISP CRISP (Cmputer Retrieval f Infrmatin n Scientific Prjects) is a searchable database f federally funded bimedical research prjects cnducted at universities, hspitals and ther research institutins. All f the research is funded by the Department f Health and Human Services (which includes the NIH). Search On frnt CRISP page, hit G t CRISP query frm buttn Search asthma children smking, making sure the Glbal lgic is AND and Expansin lgic is stem (will search fr wrds with the same stem r rt). Here yu can see what ther researchers are lking int, and what was successful getting federal funding. Fundatin Center Prvides backgrund, statistics, and updated infrmatin n grant-makers and grants, including a directry that we have in print (we d nt have a subscriptin t the nline versin). Designed t cnnect nn-prfit rganizatins with grant-making institutins. We can use it t find philanthrpic rganizatins that wuld be likely t ffer applicable grants. Search Frm Grants and Funding A-Z under recmmended websites On left side f the page, lk at check statistics G t Tp Funders The Gates and Wd fundatins bth fund a lt f health related research Ntice that each fundatin has infrmatin fr grant seekers. Take a lk at ther fundatins as well t see if there is a pssibility f getting grants frm the rganizatin in the future. We dn t have access t the nline fundatin directry, but we d have it available in print. There is ne brwseable sectin by subject g t Find Funders, then n right side, fllw the small link t Brwse RFP s then brwse health. Research resurces fr BUMC Site run by BUMC t bring tgether investigatrs wh are studying varius research tpics at BUMC. Students are encuraged t use the site fr research expertise and pprtunities. Yu can

6 search by research tpic, investigatr, funding agency, equipment and/r technique. Yu can als search fr individuals wh d nt necessarily have funded research prjects but wh have identified an interest in a particular tpic. Listed n 'Grants and Funding' subjects A-Z page G int Have expressed an interest in a particular research tpic. Search asthma Imagine yu'd like t spend even mre time n yur thesis tpic, and want t pursue further research with yur newfund expertise. Using the resurces abve, find a grant that yu culd apply fr in the future, r a researcher at BU yu'd like t cllabrate with.

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