2014 Novartis Foundation Report CAMTech India: Technologies for RMNCH. 1 P age

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1 2014 Novartis Foundation Report CAMTech India: Technologies for RMNCH 1 P age

2 Table of Contents 1. Executive Summary 2. Key Initiatives 2.1. CAMTech India Clinical Summit 2.2. CAMTech India Technology Showcase 2.3. CAMTech India Jugaad- a- thon 2 P age

3 1. Executive Summary In July 2014, Novartis Foundation supported the CAMTech India initiative focused on accelerating affordable medical technologies to improve Reproductive, Maternal, Newborn and Child Health (RMNCH) outcomes. The CAMTech India Jugaad- a- thon marked a novel approach to innovation and development of new healthcare technologies to improve RMNCH care. In essence, it catalyzed the creation of more accessible, affordable solutions in a 48 hour period to healthcare problems while tapping into India s huge intellectual capital. Through this support, the Novartis Foundation: Participated in the CAMTech India Clinical Summit held on July 18 th 2014 and engaged with a diverse group of stakeholders to gain insight into pressing clinical challenges faced in the India around RMNCH care. Showcased Novartis Foundation s ICATT technology, an Innovative e- learning tool for training in childhood illnesses developed in collaboration with WHO to entrepreneurs, industry and public health experts. Inspired a global community of innovators at the CAMTech India Jugaad- a- thon (July 19-20, 2014) to work on the key challenges identified by Novartis Foundation in regards to access to information and early diagnosis of leprosy. Played a vital role at CAMTech India Jugaad- a- thon by engaging with highly- talented and motivated participants from reputed academic institutions and organizations and mentoring them to develop disruptive and scalable innovations. Gained access and exposure to global health experts and CAMTech network in India. Through CAMTech s judging counsel, the team addressing the challenge of early diagnosis of leprosy was selected as the winner of the Novartis Foundation Prize. A monetary prize of 50,000 INR was provided to the team. The winning team is continuing to receive mentorship from key personnel at Novartis Foundation. In addition, the team addressing the challenge of access to information won the CAMTech India Jugaad- a- thon first prize award and a monetary prize of 2,50,000 INR. This engagement with Novartis Foundation demonstrates a mutually beneficial collaboration between CAMTech and Novartis Foundation. CAMTech is actively seeking other opportunities to collaborate with Novartis Foundation that will enable both organizations to drive innovation and improve health outcomes in low- and middle- income countries. 3 P age

4 2. Key Initiatives Novartis Foundation engaged with CAMTech to primarily support the CAMTech India Jugaad- a- thon. This initiative was instrumental in driving affordable medical technology innovation to improve RMNCH outcomes in India. In addition, Novartis Foundation participated and contributed to the success of CAMTech India Clinical Summit and CAMTech India Technology showcase, two other key initiatives as part of the CAMTech India Program. This report outlines a summary of each of these events in detail. 2.1 CAMTech India Clinical Summit Ms. Elizabeth Bailey kicking off the CAMTech India Clinical Summit with the introductory panel on Co- Creation: Can it help drive technology innovation in RMNCH care? The CAMTech India Clinical Summit brought together over 120 physicians, nurses, ASHA workers, government and industry representatives and public health experts across India with the primary objective of identifying pressing clinical needs faced in RMNCH care. The event took place prior to the Jugaad- a- thon and served as a pivotal activity to provide insight into the Indian clinical environment and generated over 100 clinical challenges that then became the foundation for innovative ideas over the next 48 hours. Highlights: 95+ participants 25+ panelists 100+ clinical challenges identified 66 organizations represented CAMTech India Clinical Summit provided a platform to uncover pressing clinical challenges in delivering and accessing RMNCH care in India and served as a pivotal activity to drive affordable medical innovation. 4 P age

Left: RMNCH challenges were sourced through out the clinical summit on physical white boards at the event.

Narayana Health, Glocal Healthcare, Bangalore Medical College, National Health Systems Resource Center and Public Health Foundation of India

The clinical summit also provided key thought- leadership around Co- Creation by engaging healthcare provides across the continuum of care

This provided a very unique opportunity for a global community of innovators to understand the clinical needs at the frontline of healthcare

A total of 106 clinical challenges were identified during the course of the day and shared with the Jugaad- a- thon participants.

5 Left: RMNCH challenges were sourced through out the clinical summit on physical white boards at the event. Right: Critical insights into healthcare delivery at the last mile shared by an ASHA worker and translated by a volunteer. Narayana Health, Glocal Healthcare, Bangalore Medical College, National Health Systems Resource Center and Public Health Foundation of India were among the 66 organizations that contributed to identifying critical needs as well as best practices in RMNCH care. The clinical summit also provided key thought- leadership around Co- Creation by engaging healthcare provides across the continuum of care (ASHA workers to specialized surgeons). This provided a very unique opportunity for a global community of innovators to understand the clinical needs at the frontline of healthcare delivery not only in the city hospitals but also in remote villages across India. A total of 106 clinical challenges were identified during the course of the day and shared with the Jugaad- a- thon participants. CAMTech India Clinical Summit Panels: 1. Co- Creation: Can it help drive technology innovation in RMNCH? 2. RMNCH Needs in India: Perspectives from Healthcare Providers 3. Voice of the Patient: Challenges in Accessing Quality RMNCH Care 4. Problem Statement and Pitch Workshop 5. Lessons Learned about Medical Technology Innovation 6. Role of the Indian Government in Enabling Innovation for RMNCH 5 P age

Thoughts and direction from key opinion leaders expressed at the

Tweets The Clinical Summit also included an interactive Problem

Kris Olson, Medical Director of CAMTech and Ms.

successfully engaged every participant of the summit to identify

burden of disease, Who is currently impacted, and Why are the

This workshop alone sourced 75 clinical challenges from the

6 Thoughts and direction from key opinion leaders expressed at the CAMTech India Clinical Summit Image Source: GE Healthcare India Tweets The Clinical Summit also included an interactive Problem Statement and Pitch workshop led by Dr. Kris Olson, Medical Director of CAMTech and Ms. Smitha Gudapakkam, Business Development Manager of CAMTech, that successfully engaged every participant of the summit to identify problems and prioritize them based on three criteria: What is the burden of disease, Who is currently impacted, and Why are the current solutions failing? This workshop alone sourced 75 clinical challenges from the Clinical Summit attendees and provided a platform for Co- Creation. Teams working through the Problem Statement and Pitch workshop to identify prioritize and pitch RMNCH needs. 6 P age

2.2 Technology Showcase Participants at the Technology Showcase engaging with entrepreneurs and their novel technologies that make an impact in RMNCH care in India Following the Clinical Summit,

The Technology Showcase provided opportunities for both upcoming entrepreneurs, as well as established healthcare companies, to showcase their technology innovations addressing public health needs to

These cutting edge, impactful technologies included teams from fourteen different institutions across India, Uganda and the United States.

7 2.2 Technology Showcase Participants at the Technology Showcase engaging with entrepreneurs and their novel technologies that make an impact in RMNCH care in India Following the Clinical Summit, CAMTech held its first Technology Showcase, at which eighteen medical technologies addressing RMNCH needs in India were showcased. The Technology Showcase provided opportunities for both upcoming entrepreneurs, as well as established healthcare companies, to showcase their technology innovations addressing public health needs to a diverse group of stakeholders (end- users, government officials, and various multilaterals) and potential purchasers. These cutting edge, impactful technologies included teams from fourteen different institutions across India, Uganda and the United States. The technologies showcased included a low- cost patient monitoring system designed for ICUs in India from Glocal Healthcare, ICATT by Novartis which is an innovative software application to support the implementation of the WHO/UNICEF strategy on the Integrated Management of Childhood Illness (IMCI), the Lullaby Warmer series by GE Healthcare and Need- U- Ma, a Postpartum Hemorrhage Control Device developed by Vellore Institute of Technology. 7 P a g e

Teams at the Technology Showcase providing an overview and getting feedback on their novel technologies from a community of innovators attending the Clinical Summit/Jugaad- a- thon 2.

Private Systems Ltd (CAMTech s lead local implementation partner). The event was hosted by GE Healthcare India at the John Welch Technology Center in Bangalore, India.

8 Teams at the Technology Showcase providing an overview and getting feedback on their novel technologies from a community of innovators attending the Clinical Summit/Jugaad- a- thon 2.3 CAMTech India Jugaad- a- thon The CAMTech India Jugaad- a- thon marked the completion of a significant milestone in the CAMTech India program and was organized by CAMTech and Glocal Healthcare Private Systems Ltd (CAMTech s lead local implementation partner). The event was hosted by GE Healthcare India at the John Welch Technology Center in Bangalore, India. The Jugaad- a- thon marked a novel approach to innovation and development of new healthcare technologies to improve RMNCH care. In essence, it enabled the creation of more accessible, affordable solutions to healthcare problems while tapping into India s huge intellectual capital. In July of 2014, over 300 of India s best minds in medicine, engineering and business gathered at GE s John Welch Technology Center to develop innovative and affordable health technologies to save the lives of women and children across India. Ms. Elizabeth Bailey, Director of CAMTech addressing 240+ participants and 70 mentors, eagerly waiting to kick off the CAMTech India Jugaad- a- thon. 8 P age

Top Left: Terri Bresenham, President & CEO, GE Healthcare India & South Asia Managing Director, Wipro GE Healthcare welcomes the CAMTech India participants to GE s Jack Welch Technology Center Top

fetal life support system. Bottom Left: Dr. Ann Aerts, Head Novartis Foundation for Sustainable Development shares the challenges around diagnosing & treating leprosy in children.

The event was launched with inspiring keynotes from experts and thought- leaders in the healthcare field, who identified and presented challenges to a global community of innovators.

public health and business, to develop new tools to improve health. - Elizabeth Bailey, Director of the Consortium for Affordable Medical Technologies (CAMTech) at Massachusetts General Hospital.

9 Top Left: Terri Bresenham, President & CEO, GE Healthcare India & South Asia Managing Director, Wipro GE Healthcare welcomes the CAMTech India participants to GE s Jack Welch Technology Center Top Right: Syed Ahmed Mushtaque, Manager, Clinical Alliances, Covidien India Engineering Center presents challenges around three verticals: post- partum hemorrhage, maternal & fetal health monitoring & fetal life support system. Bottom Left: Dr. Ann Aerts, Head Novartis Foundation for Sustainable Development shares the challenges around diagnosing & treating leprosy in children. Bottom Right: Soura Bhattacharya, Glocal Healthcare s Chief of Medical Technology on behalf of AB InBev orients participants about the impact of road- safety challenges on child health in India. The event was launched with inspiring keynotes from experts and thought- leaders in the healthcare field, who identified and presented challenges to a global community of innovators. The Jugaad-a-thon (derived from the Hindi word for workaround, jugaad) is a new way of elevating the experience and know-how of local experts and using strategies from not just engineering, but also public health and business, to develop new tools to improve health. - Elizabeth Bailey, Director of the Consortium for Affordable Medical Technologies (CAMTech) at Massachusetts General Hospital. As a healthcare provider to those most at risk for poor health and early death in India, hackathons help us become a part of a unique community of innovators who share our vision of ensuring the best health care is available to all,... We see this effort (CAMTech India Jugaad-a-thon) as central to improving the lives of the millions we serve. - Soura Bhattacharyya, Glocal Healthcare s Chief of Medical Technology 9 P age

In addition to the 100+ clinical challenges identified at the preceding CAMTech clinical summit, participants pitched a total of 78 self- identified pain points at the Jugaad- a- thon.

medicine chose the Global Health Technology Track.

Cross- disciplinary teams formed and worked alongside mentors to hack technical solutions, develop rapid prototypes, and map early business models for widespread and sustainable public health impact.

4 Teams focused on the challenges posed by Novartis Foundation. CAMTech-USAID Medical Hack-athon is a great platform to innovate and showcase ideas among peer group.

This recognition gives us further impetus to develop a prototype of this design and thus take it to the next level. Dr.

10 In addition to the 100+ clinical challenges identified at the preceding CAMTech clinical summit, participants pitched a total of 78 self- identified pain points at the Jugaad- a- thon. Over 240 participants and 70 mentors participated in the CAMTech India Jugaad- a- thon (representing over 100 different organizations) with diverse backgrounds in engineering, business, design and medicine chose the Global Health Technology Track clinical challenges identified in the preceding CAMTech India Clinical Summit and 70+ pitches self- identified as pain points by participants sparked a significant motivation for innovation. Cross- disciplinary teams formed and worked alongside mentors to hack technical solutions, develop rapid prototypes, and map early business models for widespread and sustainable public health impact. In 48 hours, teams developed 31 breakthrough innovations that had the potential to transform women and child health in India and around the world. 4 Teams focused on the challenges posed by Novartis Foundation. CAMTech-USAID Medical Hack-athon is a great platform to innovate and showcase ideas among peer group. We are glad that our design has been recognized, especially aimed at addressing one of the pressing issues in the reproductive and maternal sciences. This recognition gives us further impetus to develop a prototype of this design and thus take it to the next level. Dr. Lavanya Kiran, Consultant, Obstetrics and Gynecocology at Narayana Health City (Bangalore, India) Hacking Store: CAMTech hack- a- thons encourage participants to explore building prototypes of their innovations when required. This methodology helps answer critical questions at each stage of the product development cycle and creates room for multiple rounds of iterations on product design based on end- user feedback. The CAMTech India Jugaad- a- thon provided participants with a comprehensive list of prototyping materials to be used during the 48 hours event. 10 P age

Mentors played a vital role by sharing their expertise in health, engineering and/or business to aid in the development of new tools and technologies.

11 Participants had access to a comprehensive set prototyping materials through an on- site hack- store. Mentorship CAMTech recruited 70 mentors to attend and support teams throughout the 48 hour duration of the hack- a- thon. Mentors played a vital role by sharing their expertise in health, engineering and/or business to aid in the development of new tools and technologies. Specifically, mentors: Provided insight to pressing clinical challenges in RMNCH care delivery in India. Co- created alongside engineers, entrepreneurs and other clinicians, technologies that reduce barriers to RMNCH care. Provided end- user input to design technologies that have high adoption potential. Advised on business models that will ensure commercial viability. I've been in Medicine for the last 24 years, and have been a Pediatrician for the last 15 years...but in all these years, I've never had the opportunity to participate (and mentor) in an event quite like the Jugaad-a-thon. As clinicians, the vast majority of us are ensconced in our work and our academics...and rarely look for (let alone find) opportunities for cross-disciplinary interactions. When I witnessed the co-creativity of people with different skills and talent, sitting together and solving these problems...and ACTUALLY coming-up with workable solutions. It was pretty awesome!! Dr. K. Mahesh, Clinical Professor, Department of Pediatric Cardiology, Pediatric CMR Services, Amrita Institute of Medical Sciences and Research Center It was wonderful to see the enthusiasm and energy among the young participants! We need more such platforms to bring the bright minds from different streams together. The proper follow through and transformation of these ideas into product in the market is the key to making a real difference to our world. - Dr. Nilima Kadambi, Executive Director - Pharma Div at Belle Sante - India 11 P a g e

Mentors representing expertise in health, business and engineering coach and guide teams with their ideas and innovations Awards CAMTech evaluates

technically- disruptive and commercially- viable.

CAMTech- MUST or a clear public health need Public Health Impact Demonstrates potential for widespread public health impact in LMICs Technology

12 Mentors representing expertise in health, business and engineering coach and guide teams with their ideas and innovations Awards CAMTech evaluates and measures all innovations based on a set criteria and rewards the most promising technologies that are not only clinically- impactful but also technically- disruptive and commercially- viable. The top three innovations were awarded monetary prizes along with 3 years of incubation support and office space at Mazumdar- Shaw Cancer Center at Narayana Health Hospitals. CAMTech Judging Criteria: Category Description of Category Challenge Addressed Shows innovation is addressing one of the challenges identified by CAMTech- MUST or a clear public health need Public Health Impact Demonstrates potential for widespread public health impact in LMICs Technology Innovation Offers new and creative technology solution ( better/faster/cheaper ) Provides convincing rationale for why this unique approach has the potential to work (if not already developed) Addresses significant technical issues relevant for low- resource settings (e.g., low- cost components, intermittent power supply, parts replacement, unskilled health workers, etc.) 12 P age

Sustainable Business Model Demonstrates strong demand (social, clinical and/or economic impact) Identifies a clear revenue model Demonstrates novelty of the technology in comparison to competitors

13 Sustainable Business Model Demonstrates strong demand (social, clinical and/or economic impact) Identifies a clear revenue model Demonstrates novelty of the technology in comparison to competitors Evaluates and demonstrates distribution and adoption of technology Team Brings cross- disciplinary expertise in technology development, clinical medicine and business Incorporates end- user input/feedback Pitch Demonstrates the prototype or solution Clearly articulates the problem the technology proposes to address Documents plan to work in the field and continually incorporate end- user feedback CAMTech India Jugaad-a-thon Judges: David Bangsberg (Director, MGH Center for Global Health) Soura Bhattacharyya (Chief Technology Officer, Glocal Healthcare) Rani Desai (Head - Strategy & Operations, Biocon Foundation) Elizabeth Bailey (Director, CAMTech) Archana Patel (Professor, Head of the Dpt. and Director of Clinical Epidemiology, Indira Gandhi Govt. Medical College. & Vice President, Lata Medical Research Foundation) Shirshendu Mukehrjee (Strategic Advisor, R&D Initiative - India, Wellcome Trust) Jasjit Mangat (Executive Chairman, Agni Energy) Judges representing a diverse range of expertise, deliberating during the final presentations at the CAMTech India Jugaadathon 13 P age

BabySteps, which aids in early diagnosis of

system developed to diagnose a condition

occurs when the baby s head is too large to

14 First prize (2,50,000 INR.) went to a mobile application called BabySteps, which aids in early diagnosis of developmental delays in children. The second place prize (1,50,000 INR.) was awarded to PEL- Dia, a measurement system developed to diagnose a condition called Cephalo Pelvic Disproportion (CPD occurs when the baby s head is too large to pass through the mother s pelvis). Third prize (75,000 INR) was awarded to Pregmatic, a wearable device that empowers pregnant women to remember important Antenatal care and immunization visit dates. 14 P age

The Novartis Foundation Prize (50,000 INR) was awarded to Team Leprosy

a person having leprosy using image processing, pressure sensing and neural

This mechanical, electricity free CPAP technology provides the opportunity for

$immediate first aid response to a bone fracture.$

15 The Novartis Foundation Prize (50,000 INR) was awarded to Team Leprosy Predictor who developed a novel mobile application that predicts the chances of a person having leprosy using image processing, pressure sensing and neural networks. The Covidien CARES Prize (50,000 INR) was awarded to Team Saans. This mechanical, electricity free CPAP technology provides the opportunity for distressed babies born in peripheral facilities to receive effective positive airway breathing support. The AB InBev Prize (50,000 INR) was awarded to Team Fxii, a cost effective, immediate first aid response to a bone fracture. It is modeled like a spray can that can be applied directly on the fractured area, and it solidifies into a hard mass, immobilizing the area till the patient reaches the hospital. 15 P a g e

16 Additional Awards WELLCOME TRUST MENTORSHIP AWARD: The Wellcome Trust committed to provide mentorship to three teams to develop grant and/or fundraising proposals. BabySteps: A unique and integrated mobile app for early diagnosis of developmental delays in children across India. Milky Way: A novel technique that aims to addresses any inability of babies to breast- feed naturally due to lack. This technique nurtures the bond between mother and child while facilitating feeding in the most natural way possible. Fxii: A cost effective, immediate first aid response to a bone fracture. It is modeled like a spray can that can be applied directly on the fractured area. It solidifies into a hard mass, immobilizing the area till the patient reaches the hospital. DAYANANDA SAGAR INCUBATOR PRIZE: Dayananda Sagar Institution s Incubator offered 3 months of incubation support, office space and possible scale up support after 3 months to: The Pneumaniacs: An easy to use device that detects early signs of respiratory distress in infants and alerts end users to trigger the right intervention. INNACCEL ACCELERATION PRIZE: InnAccel Inc offered a month of acceleration services to: Saans: A mechanical, electricity free CPAP technology that provides the opportunity for distressed babies born in peripheral facilities to receive effective positive airway breathing support. Press Highlights The following table highlights where CAMTech India has been featured in the press. Publication Headline Page Pre- Event announcement 2nd July 2014 Economic Times Bangalore 25th June 2014 The New Indian Express Bangalore 26th June 2014 Trinity Mirror Chennai Online 24th June 2014 India Blooms Online 24th June 2014 New Kerala Online 24th June 2014 Sify Online 25th June 2014 The New Indian Express Online 26th June 2014 Color Doppler Online 26th June 2014 Express Healthcare Online 26th June 2014 India Medical Times Online 16 P age

17 26th June 2014 Medical Buyer Online 26th June 2014 Hospital Management Online 26th June 2014 Affordable Stem Cells Therapy Online 26th June 2014 Press Release Watch Online 28th June 2014 Bangalore First Online During the Event 20th July 2014 Hindu Business Line National 21st July 2014 Hindustan Times National 24th July 2014 Economic Times National 25th July 2014 Nav Bharat Times National Post Event 24th July 2014 PharmaBiz Online 25th July 2014 DNA National 29th July 2014 DNA Bangalore 29th July 2014 DNA Bangalore 27th July 2014 Times of India Bangalore Online 20th July 2014 BusinessWeek Online 22nd July 2014 Beyond Jugaad Online 23rd July 2014 Pharmabiz Online 24th July 2014 Nextbillion.co Online 24th July 2014 Doc N Doc Online 24th July 2014 DigiMed Online 28th July 2014 Biospectrum Online 29th July 2014 Bangalore this week Online 29th July 2014 Webnews wire Online 29th July 2014 India Techonline Online 17 P age

IKP Knowledge Park. Deepanwita Chattopadhyay Chairman & CEO

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