Pediatric Orthopaedic Society of North America 9400 W Higgins Road, Suite 500 Rosemont, IL (847)

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1 Pediatric Orthopaedic Society of North America 9400 W Higgins Road, Suite 500 Rosemont, IL (847) APPLICATION FOR POSNA RESEARCH GRANTS AND AWARDS (To be completed by Principal Investigator) REMINDER: THE INVESTIGATOR/DEPARTMENT CHAIRMAN/INSTITUTIONAL AUTHORIZATION FORM FOLLOWS ON THE NEXT PAGE AND MUST BE COMPLETED IN FULL Please select the research grant(s) you are applying for to fund this proposal. If you also qualify for the one of the POSNA Awards, you may apply for that award by checking the appropriate award box and submitting any other documents required for that particular award. See award descriptions online for eligibility criteria and submission requirements. Each grant and award will be for up to 30,000, unless otherwise stated below. GRANTS POSNA Directed Research Grant (2 available up to 50,000 each) POSNA Research Grant (4 available) Clinical Trials Planning Grant Zimmer Biomet Spine Research Grant AWARDS Angela S. M. Kuo Award Arthur Huene Memorial Award St. Giles Award POSNA Research Start Up Grant (3 available up to 10,000 each) Type of Study: Basic Science Clinical Research Spine-Basic Science Spine-Clinical Research Is this application: New Application Re-submission Date: Total Amount Requested for Project: TITLE OF PROJECT: This request is made by the undersigned who also agrees to comply with the following: It is understood and agreed to by the applicant: (1) that funds granted as a result of the request are to be expended for the purposes set forth herein; (2) that the grant may be terminated in whole, or in part, at any time, by the Pediatric Orthopaedic Society of North America but that such termination shall not affect obligations made pursuant to the approved application prior to the effective date of such termination; (3) that all reports of original investigations supported by any grant made as a result of this request shall acknowledge such support provided by the Pediatric Orthopaedic Society of North America; (4) that the applicant will request that the project be revised whenever the approved plan of operation, or method of financing, is materially changed; (5) that any invention arising out of the activities assisted by this grant will be promptly and fully reported to the Pediatric Orthopaedic Society of North America; (6) that where the grant activity results in a book or other copyrightable material, the author is free to copyright, but the Pediatric Orthopaedic Society of North America reserves a royalty-free, nonexclusive, and irrevocable license to reproduce, publish, translate, or otherwise use, and to authorize others to use, all copyrightable or copyrighted material resulting from the grant-supported activity; (7) that reports will be made as required and necessary records and accounts, including financial and property controls, will be maintained and made available to the Pediatric Orthopaedic Society of North America. PRINCIPAL INVESTIGATOR NAME: CO-PRINCIPAL INVESTIGATOR NAME(S): INSTITUTION NAME: The POSNA Research Committee reserves the right to consider your application for a grant in a different category, if deemed beneficial to you. Revised: 8/31/13 1

2 Pediatric Orthopaedic Society of North America 9400 W Higgins Road, #500 Rosemont, IL (847) INVESTIGATOR/DEPARTMENT CHAIRMAN/INSTITUTIONAL AUTHORIZATION TO SUBMIT APPLICATION PRINCIPAL AND CO-PRINCIPAL INVESTIGATOR INFORMATION: PRINICIPAL INVESTIGATOR: Name: Title: Department: Address: Signature: Phone: FAX : CO-PRINCIPAL INVESTIGATOR (if Applicable) Name: Title: Department: Phone: FAX: Signature: DEPARTMENT CHAIRMAN INFORMATION: Name: Title: Department: Phone: FAX: Signature: OTHER INVESTIGATORS ASSOCIATED WITH PROJECT Name: Signature: Title: Department: Name: Title: Department: FINANCIAL OFFICER INFORMATION: Name: Title: Address: Signature: Signature: Phone: FAX: Mailing Address for Check: NAME OF MEDICAL INSTITUTION/ORGANIZATION SIGNATURE OF OFFICIAL AUTHORIZED TO SIGN FOR INSTITUTION/ORGANIZATION: 2

3 BUDGET FOR ENTIRE PROJECT: DIRECT COSTS ONLY SALARIES AND WAGES % of Time (OMIT CENTS) (List all personnel for whom money is requested) on This Project Amount % % % % Fringe Benefits % of Salaries and Wages Subtotals: Subtotals: Salaries and Wages plus Fringe Benefits PERMANENT EQUIPMENT (Justification required) Amount Subtotals: CONSUMABLE SUPPLIES (Exclude animals and animal care) Amount Subtotals: ANIMALS AND ANIMAL CARE Amount Subtotals: ALL OTHER EXPENSES Amount Subtotals: Total Direct Costs: PROVIDE BUDGET JUSTIFICATION FOR THE YEAR AND STATE WHAT EACH PERSON ON THE GRANT WILL BE DOING: (Use Page 4) 3

4 Pediatric Orthopaedic Society of North America 9400 W. Higgins Road, Suite 500 Rosemont, IL (847) BUDGET JUSTIFICATION Provide Budget Justification for the Year and State What Each Person on the Grant Will be Doing: 4

5 BIOGRAPHICAL SKETCH Provide the following information for the Senior/key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FIVE (5) PAGES PER PERSON. NAME era COMONS USER NAME POSITION EDUCATION/TRAINING (Begin with baccalaureate or other professional education, such as nursing, include postdoctoral training and residency training, if applicable). INSTITUTION AND LOCATION DEGREE(circle highest degree) COMPLETION DATE FIELD OF STUDY. PERSONAL STATEMENT: POSITIONS AND HONORS: 5

6 CONTRIBUTIONS TO SCIENCE: ADDITIONAL INFORMATION: Research Support and/or Scholastic Performance: 5a

7 FACILITIES LABORATORY SPACE AND MAJOR EQUIPMENT AVAILABLE: RESEARCH SUPPORT (Please show recipient of funding with P for Principal or CP for Co-Principal Investigator) RESEARCH SUPPORT TO PRINCIPAL INVESTIGATOR OR CO-P.I. RELEVANT TO THIS PROJECT PAST 5 YEARS (INCLUDE SUPPORT FROM OWN INSTITUTION): SOURCE RECIPIENT TITLE OF PROJECT AMOUNT PERIOD OF SUPPORT SUPPORT TO PRINCIPAL INVESTIGATOR OR CO-P.I. FOR OTHER RESEARCH PROJECTS FOR PAST 5 YEARS (INCLUDE ALL CURRENT RESEARCH GRANTS attach additional pages as necessary): SOURCE RECIPIENT TITLE OF PROJECT AMOUNT PERIOD OF SUPPORT CURRENT RESEARCH FUNDING WITH OVERLAP WITH THIS PROPOSAL: SOURCE RECIPIENT TITLE OF PROJECT AMOUNT PERIOD OF SUPPORT PENDING GRANTS WHICH HAVE OVERLAP WITH THE CURRENT PROPOSAL: SOURCE RECIPIENT TITLE OF PROJECT AMOUNT PERIOD OF SUPPORT 6

8 ABSTRACT OF RESEARCH PLAN NAME TITLE INSTITUTION LAY AND PROJECT SUMMARY OF RESEARCH PLAN: PLEASE PROVIDE 15 LINE LAY SUMMARY AND A 35 LINE PROJECT SUMMARY. SEE BELOW FOR RESEARCH PLAN AND SUPPORTING DATA FOR INSTRUCTIONS. LAY SUMMARY: PROJECT SUMMARY: 7

9 RESEARCH PLAN AND SUPPORTING DATA Grants should emphasize the following: a. Potential to have a profound effect on the quality and/or safety of the orthopaedic care of children. b. Potential applicability on a global level. c. Clear and measurable outcomes. d. Ability to successfully complete the funding proposal as measured by past experience, preliminary data and pilot work. e. Potential for expanded research, future publications and continued (extramural) grant funding. f. Collaborative nature of the grant (number of investigators and institutions involved. IMPORTANT: Please take note that some of the POSNA grant format has changed. This is to align with the standards of the NIH RO3 and R21 granting mechanisms to facilitate applicants to apply for federal funding without restructuring their grants. If the proposal does not comply with the following specifications, it will be returned to the applicant. 1) Required Documents: 1) Lay Summary 2) Project Summary 3) Specific Aims 4) Research Strategy 5) References 6) Role of Orthopaedic Surgeon 7) Animal IACUC or Human IRB Statement if applicable 8) Supplemental material if applicable 2) Document Descriptions: 1) Lay Summary: Lay summary is a brief summary of a research project or a research proposal that has been written for members of the public, rather than researchers or professionals. It should be written in plain English, avoid the use of jargon and explain any technical terms that have to be included. These summaries are essential to communicate to the public the focus of POSNA research. 2) Project Summary Include the project s broad, long-term objectives and specific aims. Include a description of the research design and methods for achieving the stated goals. Write in plain language, so even a non-scientist can understand the importance of the project. This summary most contain a statement of relevance of the project to the mission of the Pediatric

10 Orthopaedic Society of North America. This is a condensed version of the specific aims. These summaries are essen-tial to communicate to the scientific community the focus of POSNA research. 3) Specific Aims Briefly state: Significance, Hypothesis, Innovation and Impact if hypothesis is proven true and delineate the specific aims for the project with brief description of methods. This is the blue-print of the proposed project. It serves as an overview for reviewers of your grant and allows others who were not assigned to read your grant gain a quick overview of your proposal so that they can participate in discussion of your grant. 4) Research Strategy Background: Significance: Explain the epidemiology, morbidity, mortality and cost of the clinical problem. Provide the context of the proposed work and summarize the relevant literature regarding historical and current treatments and why they are limited. Hypothesis: Clearly state a hypothesis and provide rationale for the hypothesis. Innovation: Explain how the hypothesis is innovative. Immediate and Long Term Impact: Explain what part of clinical significance would change if your hypothesis is proven true both a) from the work proposed witching and b) from future work stemming off of the broader theory of your work. Approach: Give details of your research plan, including how the results will be analyzed. For each specific aim mentioned in "A", show how your plan is expected to fulfill the aim. Sample Size: Power studies justifying sample sizes, and therefore cost of the grant, are required. If not applicable, an explanation as to being exempt is required. Timeline: Delineate a plan as to when the research will be completed. Be sure that the plan is not overly ambitious. 5) References Not counted against research strategy listed immediately after research strategy 6) Role of Orthopaedic Surgeon Provide statement, clarifying role of orthopaedic surgeon, stating significant part taken in the planning and/or execution of the design and analysis of model. Simple technical roles such as obtaining tissue samples at surgery or providing patients for analysis are not generally considered to be substantial roles. 7) Animal IACUC or Human IRB

11 8) Supplemental Material: (Pilot Study, Figures, and/or Appendices if necessary) On projects where human subjects are placed at some risk, in some cases where animals are used for experimentation, or where there is a laboratory methodology with which the applying institution has not had well documented experience, the investigator may submit a pilot study. In some cases, the applicant may want to provide a copy of a questionnaire or outcomes instrument as supplementary information for the grant reviewers, especially if the instrument is not readily available in the literature. Figures may be submitted in the supplementary material, rather than in the body of the grant. Please be advised, however, that the reviewers will be primarily assessing the main body of the proposal (sections A through E). Material that is crucial for the assessment of the proposal should be included in the main body of the grant, not in the supplementary information. 3) Page Limits: 1) Lay Summary: 15 lines of text or less 2) Project Summary: 35 lines of text or less 3) Specific Aims: 1 Page 4) Research Strategy: 6 Pages including figures and media 5) References: 2 pages 6) Role of Orthopaedic Surgeon: 15 lines of text 7) Animal IACUC or IRB: Unlimited 8) Supplemental Material: Unlimited however, this section may not include material essential for grant review, i.e. methodology etc. 4) Paper Size and Margins Use paper size no larger than standard letter paper size (8 ½" x 11 ). Provide at least one-half inch margins (top, bottom, left, and right) for all pages. No applicant-supplied information can appear in the margins. 5) Font (size, color, type density) and Line Spacing Adherence to font size, type density, line spacing and text color requirements is necessary to ensure readability and fairness. Although font requirements apply to all attachments, they are most important and most heavily scrutinized in attachments with page limits. Text in your attachments must follow these minimum requirements: Font size: Must be 11 points or larger. Smaller text in figures, graphs, diagrams and charts is acceptable, as long as it is legible when the page is viewed at 100%.

12 Some PDF conversion software reduces font size. It is important to confirm that the final PDF document complies with the font requirements. Type density: Must be no more than 15 characters per linear inch (including characters and spaces). Line spacing: Must be no more than six lines per vertical inch. Text color: No restriction. Though not required, black or other high-contrast text colors are recommended since they print well and are legible to the largest audience. We recommended the following fonts, although other fonts (both serif and non-serif) are acceptable if they meet the above requirements. Arial Georgia Helvetica Palatino Linotype Legibility is of paramount importance. Applications that include PDF attachments that do not conform to the minimum requirements listed above may be withdrawn from consideration. 11

West Virginia Clinical and Translational Science Institute Small Grants RFA

West Virginia Clinical and Translational Science Institute Small Grants RFA Part 1. Overview Information Limited funds are available for the WVCTSI Small Grants Program to support small, welldefined projects